TCONS_00004312-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004312-protein
Unique NameTCONS_00004312-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length977

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004312-protein ID=TCONS_00004312-protein|Name=TCONS_00004312-protein|organism=Clytia hemisphaerica|type=polypeptide|length=977bp
EKQIAKYYKTNNYPSEKKRLHKTLMVTQAKSKNMYLVFCILALFVCHSLQ
QCTNSDFYEKQIKNHNIETRLTYLENGNYTIQALLVFSEMNTKCGQISKS
GLISMFSIRYAIGKFNDDPFYGSRARIGLQLDDSCGQLPTTMARGIEVVS
FHRNNSVCRSDFIRCNKDDVKNVDIKEASALIGTLMSFTTIPLSSLMSLY
DIPQVSPSASSRLLSKKELYKSFFRTISSDTNQIKAMLDIFKKFKWNYIF
AVGSDDDYGKLGVSDLKQLTSSLEGKEKICIYKDEYIPYQSEKTESKIKE
VVSKIKEGKDAKVVVLFLYVESIGERIIAEAQRQGVERIWLTSEAWNPAA
ATIFSKKLNLQNQTHGILSVSLQSHKLPKLQNYIKKEVLTNYKCNKWLQQ
YIQNMWGCQIDTLRQSDKAFTCQGSSEVVNSSIVIRELVTELPGGTDRLI
DAGYALGLAMNTVLNQTCPRGGSKCQIPKLRPADITDAMEKISFINDQGK
NITFNKDGEPTTAFYTIENLVHDGEKMVYQPIGNWSEKNLQLDVDAIQWP
YWFEKNTTVGEIDFPSSRCSRECQPGEFVVGRTGCCWNCHKCLSYKNYTD
TPMLDKCKTCQKYYHTLDNKVCIPTEIKWLEINDPAGMSIVIISAIGFLA
TFATTIFIAKYNALVTLYDSSKHMLSFVCVLLFLTFIYGPLHILEPNDAL
CKFRNGYFFILLMMYCAFVLVQTQAMTSYLKGHADRTFGGILLATQLLVL
LMFFLLELVSVIAWLYVDGYQLKEDRDTTSQVILKQCEVEFTAARLVSTF
IPCIILIIATFCAFRERNADHSFYEPKFLSFSCIALCIIIVAFLPTFRYV
VGIYKAIVLAYTMNVFGFTFLVCLILPKVYVGVIRKRRGKDEYPLKKSAT
KRKKNKKEDKKKQNDTQLETTSVIETTMTRPLGTVDNSTSEVSDTADIRL
DEKQLNGKQHSEQLTFSNGGNSQGEKC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002392XLOC_002392Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004312TCONS_00004312Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000337GPCR_3
IPR011500GPCR_3_9-Cys_dom
IPR017978GPCR_3_C
IPR001828ANF_lig-bd_rcpt
IPR028082Peripla_BP_I
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004930 G-protein coupled receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 896..916
NoneNo IPR availableGENE3D3.40.50.2300coord: 75..337
e-value: 1.2E-35
score: 122.4
NoneNo IPR availableGENE3D3.40.50.2300coord: 439..513
e-value: 2.7E-4
score: 19.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 895..977
IPR000337GPCR, family 3PRINTSPR00248GPCRMGRcoord: 101..116
score: 22.66
coord: 214..233
score: 47.97
coord: 801..824
score: 21.09
coord: 746..769
score: 24.74
coord: 249..266
score: 33.33
coord: 824..845
score: 39.35
coord: 181..207
score: 33.22
coord: 116..135
score: 30.31
coord: 233..249
score: 44.49
IPR011500GPCR, family 3, nine cysteines domainPFAMPF07562NCD3Gcoord: 565..613
e-value: 5.1E-7
score: 29.5
IPR017978GPCR family 3, C-terminalPFAMPF000037tm_3coord: 649..881
e-value: 2.6E-18
score: 66.6
IPR017978GPCR family 3, C-terminalPROSITEPS50259G_PROTEIN_RECEP_F3_4coord: 636..888
score: 22.793
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 107..523
e-value: 1.2E-46
score: 159.4
IPR028082Periplasmic binding protein-like ISUPERFAMILY53822Periplasmic binding protein-like Icoord: 92..550

Blast
BLAST of TCONS_00004312-protein vs. Swiss-Prot (Human)
Match: GRM8 (Metabotropic glutamate receptor 8 OS=Homo sapiens GN=GRM8 PE=2 SV=2)

HSP 1 Score: 239.195 bits (609), Expect = 5.335e-66
Identity = 206/912 (22.59%), Postives = 402/912 (44.08%), Query Frame = 0
Query:   48 SLQQCTNSDFYEKQIKNHNIETRLTYLENGNYTIQALLVFSEMNTKCGQISKS-GLISMFSIRYAIGKFNDDPFYGSRARIGLQLDDSCGQLPTTMARGIEVVSFHRNNSVCRSDFIRCNKDDVKNVDIKEASALIGTLMSFTTIPLSSLMSLYDIPQVSPSASSRLLSKKELYKSFFRTISSDTNQIKAMLDIFKKFKWNYIFAVGSDDDYGKLGVSDLKQLTSSLEGKEKICIYKDEYIPYQSEKTESKIKEVVSKIKEGKDAKVVVLFLYVESIGERIIAEAQR--QGVERIWLTSEAWNPAAATIFSKKLNLQNQTHGILSVSLQSHKLPKLQNYIKKEVLTNYKCNKWLQQYIQNMWGCQIDTL-RQSDKAFTCQGSSEVVNSSIVIRELVTELPGGTDRLIDAGYALGLAMNTVLNQTCPRGGSKCQIPKLRPAD---ITDAMEKISFINDQGKNITFNKDGEPTTAFYTIENLVHDGEKMVYQPIGNWSEKNLQLDVDAIQWPYWFEKNTTVGEIDFPSSRCSRECQPGEF--VVGRTGCCWNCHKCLSYKNYTDTPMLDKCKTCQKYYHTLDNKVCIPTEIKWLEINDPAGMSIVIISAIGFLATFATTIFIAKYNALVTLYDSSKHMLSFVCVLLFLTFIYGPLHILEPNDALCKFRNGYFFILLMMYCAFVLVQTQAMTS-YLKGHADRTFGG-ILLATQLLVLLMFFLLELVSVIAWLYVD--------GYQLKEDRDTTSQVILKQCEVEFTAARLVSTFIPCIILIIATFCAFRERNADHSFYEPKFLSFSCIALCIIIVAFLPTF----RYVVGIY-KAIVLAYTMNVFGFTFLVCLILPKVYVGV------IRKRRGKDEYPLKKSATKRKKNKKEDKKKQNDTQLETTSVIETTMT 929
            ++ Q T+S  Y      H+I      +  G + + A     E    CG++ K  G+  + ++ YAI + N DP   S   +G+++ D+C +    + + +  V          SD    N D        + S +IG   S  +I +++++ L+ IPQ+S ++++  LS    Y  F R +  D+ Q +AM+DI     WNY+  + S+ +YG+ GV    Q++  + G   +CI + + IP +    E   ++++ ++ E  +A+ V++F   + I  RI+  A++  Q    +W+ S++W    A ++ +    +    G +++  +   +     Y +   L N + N W  ++ +  +GC++ +  +++     C G   +       R+   E  G    +IDA Y++  A++ +    CP     C  P++   D   +   +  ++F    G  +TFN++G+     Y I       +   Y+ IG+W+ + L L V+ +QW +         E   P+S CS  C+PGE    V    CCW+C +C  Y    D    + C   Q+    ++   C    I  LE + P  +  V ++ +G +AT    +   +YN    +  S + +   +   +FL +    L I  P+  +C FR  +  + +    A +L +T  +   + +G    T    I  A+QL++      ++L+ V  W  VD        G Q   D +    V+  +C++    + + S     ++++  T  A + R    +F E K + F+    CII +AF+P F    +    +Y +   L  +M++     L  L +PKVY+ +      ++KR+   +  +  +  + K  +K + +   + + E    +ET  +
Sbjct:   26 TMMQRTHSQEYA-----HSIRVDGDIILGGLFPVHAK---GERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDA--SDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGG---VCIAQSQKIPREPRPGE--FEKIIKRLLETPNARAVIMFANEDDI-RRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQ----EEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIA------RDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLC--PRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGD-APGRYDIFQYQITNKSTEYKVIGHWTNQ-LHLKVEDMQWAH--------REHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQR--PNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVL--KCDIS-DLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTS 894          
The following BLAST results are available for this feature:
BLAST of TCONS_00004312-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GRM85.335e-6622.59Metabotropic glutamate receptor 8 OS=Homo sapiens ... [more]
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