TCONS_00005618-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00005618-protein
Unique NameTCONS_00005618-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length756

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00005618-protein ID=TCONS_00005618-protein|Name=TCONS_00005618-protein|organism=Clytia hemisphaerica|type=polypeptide|length=756bp
MIFKALYSSKMLQILTILFICVNLYSCGEDKDVSTLANDENDGICKDNHC
VRVADYMKKGLNDAYDPCENFYEYACGGWKKSHKIPEKKEEYSAINELSD
NNDKLLRQFLEGTYKGELCDKKHPTDSPTIMKVKDFYTSCMNEELIEKRG
SKPIRDFIDKLGGWDVDDDFDVDTWDWKKTLQRVHAEYPAEIFFTIDVDV
DPKNKKKNIITIDQAKLSMPQIAYFTNKEALVKLVEYSTEIAMKTLKEKP
DDEVDKKKEVHQKMKAVFEFETAISKIFIPKSAKRFTRVTLEKLNEATKV
TQFNWTEHITTIFKDYDIEISKDTHVVVLSSDSYIEEMINLIKATPKNVL
SNYIMWKMVKDMVAFLDKNFTDRNNVFRKELTGVPHKKSRKEMCFKYTDE
ILGPLVGALFIRYAFCLADKQEVEEMMELIIDEFIQNVDDVNWISEHTKN
AIIKKAKAVVMKVGYPNYLFDETVFSQRYKEIEIHDNKFFENVVSIDRFS
NHRTFKKITLDVDPHQWVSVPHMANAFYVVTKNEIVIPAGILQPPFFYAK
PLPRSISYGAIGHVLGHELTHGFDTLGRKFNKNGELIAKRSLQPLMRATV
LAKNKDDQWSKESIARFSSRTNSLKEQFNKYRITDEHSDKNSLQIDGENT
LGENIADAGGVKMAYKAYRNWVKDNGEEYVLPKLNKTSDELFFIGYAQKE
CHLSTMKALTDAIKDDVHAPSMFRITGTMSNSVEFAKAFKCSATSTMNPQ
NKTSIW
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003185XLOC_003185Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00005618TCONS_00005618Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR018497Peptidase_M13_C
IPR008753Peptidase_M13_N
IPR024079MetalloPept_cat_dom
IPR000718Peptidase_M13
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 88..108
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 44..756
IPR018497Peptidase M13, C-terminal domainPRINTSPR00786NEPRILYSINcoord: 517..529
score: 41.38
coord: 557..573
score: 64.71
coord: 535..547
score: 74.54
IPR018497Peptidase M13, C-terminal domainPFAMPF01431Peptidase_M13coord: 525..754
e-value: 3.2E-55
score: 186.8
IPR008753Peptidase M13, N-terminal domainPFAMPF05649Peptidase_M13_Ncoord: 67..466
e-value: 3.1E-94
score: 316.7
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 386..756
e-value: 1.5E-98
score: 329.6
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 43..317
e-value: 2.6E-22
score: 78.8
IPR000718Peptidase M13CDDcd08662M13coord: 66..752
e-value: 0.0
score: 582.34

Blast
BLAST of TCONS_00005618-protein vs. Swiss-Prot (Human)
Match: ECE1 (Endothelin-converting enzyme 1 OS=Homo sapiens GN=ECE1 PE=1 SV=2)

HSP 1 Score: 432.565 bits (1111), Expect = 9.128e-141
Identity = 237/723 (32.78%), Postives = 391/723 (54.08%), Query Frame = 0
Query:   44 ICKDNHCVRVADYMKKGLNDAYDPCENFYEYACGGWKKSHKIPEKKEEYSAINELSDNNDKLLRQFLEGTYKGELCDKKHPTDSPTIMKVKDFYTSCMNEELIEKRGSKPIRDFIDKLGGWDVDDDFDVDTWDWKKTLQRVHAEYPAEIFFTIDVDVDPKNKKKNIITIDQAKLSMPQIAYFTNK----EALVKLVEYSTEIAMKTLKEKPDDEVDKKKEVHQKMKAVFEFETAISKIFIPKSAKRFTRVTLEKLNEA---TKVTQFNWTEHITTIFKDYDIEISKDTHVVVLSSDSYIEEMINLIKATPKNVLSNYIMWKMVKDMVAFLDKNFTDRNNVFRKELTGVPHKKS---RKEMCFKYTDEILGPLVGALFIRYAFCLADKQEVEEMMELIIDEFIQNVDDVNWISEHTKNAIIKKAKAVVMKVGYPNYLFDETVFSQRYKEIEIHDNKFFENVVSIDRFSNHRTFKKITLDVDPHQWVSVPHMANAFYVVTKNEIVIPAGILQPPFFYAKPLPRSISYGAIGHVLGHELTHGFDTLGRKFNKNGELIAKRSLQPLMRATVLAKNKDDQWSKESIARFSSRTNSLKEQFNKYRITDEHSDKNSLQIDGENTLGENIADAGGVKMAYKAYRNWVKDNGEEYVLPKLNKTSDELFFIGYAQKECHLSTMKALTDAIKDDVHAPSMFRITGTMSNSVEFAKAFKCSATSTMNPQNKTSIW 756
            +C    CV V   +   ++   DPC +F+ YACGGW K++ +P+    +   + L ++N  +++  LE +           + S    K + +Y +CMNE  IE+  +KP+ + I++LGGW++   +  D  +++ TLQ V A Y    FF++ V  D KN   N+I +DQ+ L +P   Y+ NK    + L   + Y  ++    L    D+E      +  +M+ + +FETA++ I IP+  +R   +   K+  A   T     NW   + TIF  Y +EI++   +VV   + Y+E++  LI  T + +L+NY++W +V+   +FLD+ F D +  F + + G   KK+   R + C   T+  LG  +G +F++  F    K    E++  I   F +++  + W+ E T+ +  +KA A+   +GYPN++ D     + + +     + +FEN +    FS   T  ++    +  QW   P M NA+Y  TKNEIV PAGILQ PF Y +  P+++++G IG V+GHELTH FD  GR+++K+G      +L+P              W   S+  F  +T  + EQ++ Y +  E        ++G +TLGENIAD GG+K AY+AY+NWVK NG E+ LP L  T+++LFF+G+AQ  C + T ++  + +  D H+PS FR+ G++SNS EF++ F+C   S MNP +K  +W
Sbjct:   98 VCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA---------SVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKD--NFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLG--KLLGGGDEEA-----IRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF--YPVEINESEPIVVYDKE-YLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGT--KKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPF-YTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDG------NLRPW-------------WKNSSVEAFKRQTECMVEQYSNYSVNGE-------PVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770          
The following BLAST results are available for this feature:
BLAST of TCONS_00005618-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ECE19.128e-14132.78Endothelin-converting enzyme 1 OS=Homo sapiens GN=... [more]
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