TCONS_00005779-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00005779-protein
Unique NameTCONS_00005779-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1012

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00005779-protein ID=TCONS_00005779-protein|Name=TCONS_00005779-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1012bp
MLIKILSHIILVSSLFIVVQAKESLLFDSDEVGFRNWTVHLNDVNSPKNF
KNIHYPNKTSALTILYSDVPKYLIFVSFMSPSIDVQPAWKVFIQAEILVD
SKLSTAPYTFRMGHTSRETPDLDDDPIEDRLNDHNLHFKPSDKVEIDLTS
KSRTETFKYLYLDIWFGWGTLFEKHHPGVENVTLSSLKISYLNCPAETRN
LAFYPNTPASREKLQPVYDDGLCVTNAVKLEENLPLQRTCDDKANAKFET
GECVCDATFEKDSTGENCQLCEEGYYKSIKGHAQCQKCGKNSFNDRSTRY
ECRCGNVESGPTFRLKEEEEKKNWAADCFSYPTKVRDVKTDASSLTNDTI
GLSWSTPSNIGELKPVIYVVECIHPVAVCNLFTEYGGRREMERTQNETVI
LQNLTSHTNFTVRVCTHNEASLSNLGSDIGGKPACSAEIQDDKMTFTQDG
YPTKVLGLIVNPATVTNTISVTWQKPLSTGSNSYEYLVRYAGITEKVPEQ
NTVNKKHSFTVDDPDPERLLLDVEVLVSAKPNNGPFAGQTITGPSEIRQV
PLKAPYVDEWRTLKIALGVVGGIFGFILIIMAIVYFYRWYERKIKLHEEE
LIRIEYENRIHVNKIELLERKIDLQQEHTNLYVSMETRLGHEDPMKKIYD
SEPIYEEIPQVYNFKKFKDIQTLGEGEFGFVIKARASNICGHYGDSWVAV
KRLKVKCSAIDKEDFIGELNLLKELGHHQNVVRLLGECNDPSCIILEYLP
GGDLLGFLKKSRGYRKGSDGSEESFLTTSDLLNFSLEICEGMKHIASNGI
VHRDLAARNVLVGYNKICKISDLGLARKLNDKGYYHRNRQAKLPVRWMPL
ESIKNNIASEKSDVWSFGITLYEIFTIGGMPYPGLKSKEIPDHLATGRRM
KKPDIKTCTPEIYSLMLDCWEHRDVERPTFTQLVERIQSLQEATNDNYKN
LDIVNECDAYLDFVGDEMLGEDTVFIDPRVGSHYDVEKKLQIEISDREYL
KAEPQMNAYDKC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003279XLOC_003279Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00005779TCONS_00005779Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR011641Tyr-kin_ephrin_A/B_rcpt-like
IPR020635Tyr_kinase_cat_dom
IPR003961FN3_dom
IPR013783Ig-like_fold
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005515protein binding
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 794..812
score: 56.97
coord: 746..759
score: 44.58
coord: 862..884
score: 63.17
coord: 843..853
score: 48.7
coord: 908..930
score: 44.14
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 670..936
e-value: 1.3E-82
score: 276.9
IPR011641Tyrosine-protein kinase ephrin type A/B receptor-likeSMARTSM01411GCC2_GCC3_2coord: 257..302
e-value: 0.0065
score: 25.7
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 667..937
e-value: 1.4E-110
score: 383.3
IPR003961Fibronectin type IIISMARTSM00060FN3_2coord: 452..536
e-value: 13.0
score: 10.5
coord: 332..423
e-value: 0.0017
score: 27.6
IPR003961Fibronectin type IIIPFAMPF00041fn3coord: 342..421
e-value: 2.1E-5
score: 24.7
IPR003961Fibronectin type IIICDDcd00063FN3coord: 332..423
e-value: 0.00115635
score: 37.4759
IPR003961Fibronectin type IIICDDcd00063FN3coord: 452..513
e-value: 0.00374824
score: 35.9351
IPR003961Fibronectin type IIISUPERFAMILY49265Fibronectin type IIIcoord: 342..516
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 445..541
e-value: 5.2E-5
score: 22.9
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 330..443
e-value: 2.1E-5
score: 24.2
NoneNo IPR availableGENE3D1.20.5.510coord: 542..589
e-value: 2.2E-4
score: 20.5
NoneNo IPR availableGENE3D1.10.510.10coord: 753..1006
e-value: 1.8E-44
score: 151.4
NoneNo IPR availableGENE3D2.10.50.10coord: 255..318
e-value: 0.0014
score: 18.4
NoneNo IPR availableGENE3D2.60.40.1770coord: 193..253
e-value: 2.6E-6
score: 27.0
NoneNo IPR availableGENE3D3.30.200.20coord: 660..752
e-value: 4.1E-17
score: 61.5
NoneNo IPR availableCDDcd00192PTKccoord: 673..938
e-value: 3.26712E-113
score: 351.456
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 800..812
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 673..701
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 667..940
score: 36.343
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 648..935

Blast
BLAST of TCONS_00005779-protein vs. Swiss-Prot (Human)
Match: EPHA5 (Ephrin type-A receptor 5 OS=Homo sapiens GN=EPHA5 PE=1 SV=3)

HSP 1 Score: 230.72 bits (587), Expect = 1.463e-62
Identity = 200/778 (25.71%), Postives = 339/778 (43.57%), Query Frame = 0
Query:  182 VTLSSLKISYLNCPAETRNLAFYPNTPASREKLQPVYDDGLCVTNAVKLEENLPLQRTCDDKANAKFETGECVCDATFEKDSTGENCQLCEEGYYKSIKGHAQCQKCGKNSFNDRSTRYECRCGNVESGPTFRLKEEEEKKNWAADCFSYPTKVRDVKTDASSLTNDTIGLSWSTPSNIGELKPVIYVVECIHPVAVCNLFTEYGGR-REMERT---QNETVILQNLTSHTNFTVRVCTHNEASLSNLGSDIGGKPACSAEIQDDKMTFTQDGYPTKVLGLIVNPATVTNTISVTWQKPLSTGSNSYEYLVRYAGITEKVPEQNTVNKKHSFTVDDPDPERLLLDVEVLVSAKPNNGPFAGQTITGPSEIRQVPLKAPYVDEWRTLKIALGVVGGIFGFILIIMAIVYFY-------RWYERKIKLHEEELIRIEYENRIHVNKIELLERKIDLQQEHTNL-----YVSMETRLGHEDPMKKIYDSEPIYEEIPQVYNFKKFKDIQTLGEGEFGFVIKARASNICGHYGDSWVAVKRLKVKCSAIDKEDFIGELNLLKELGHHQNVVRLLGEC--NDPSCIILEYLPGGDLLGFLKKSRGYRKGSDGSEESFLTTSDLLNFSLEICEGMKHIASNGIVHRDLAARNVLVGYNKICKISDLGLARKL-NDKGYYHRNRQAKLPVRWMPLESIKNNIASEKSDVWSFGITLYEIFTIGGMPYPGLKSKEIPDHLATGRRMKKPDIKTCTPEIYSLMLDCWEHRDVERPTFTQLVERIQSL 940
            + L S+++ Y  CP+  R+LA +P+T    +  Q +   G CV ++V  E   P +  C  +       G+C+C A +E+ +    CQ+C  G++K+      C KC  +S+        C C           + E +    A  C   P+  R+     S++   ++ L W  P++ G  K V Y + C    +   +  E GG  R + R    +N +V++ +L +HTN+T  +   N   +S+L    G +   S  +       T    P+ V   +       N+IS++WQ+P        EY ++Y    ++       +K+ + T +   P  + +  ++        G F+ +      E    P+ A   D+ +   IA+ V  G+    ++I  ++          R        H   + R  Y       K +  E K+     H  L     Y+   T   +EDP + ++       E  +          + +G GEFG V   R   + G   +  VA+K LKV  +   + DF+GE +++ +   H N++ L G    + P  I+ EY+  G L  FLKK+ G             T   L+     I  GMK+++  G VHRDLAARN+L+  N +CK+SD GL+R L +D    +  R  K+P+RW   E+I     +  SDVWS+GI ++E+ + G  PY  + ++++   +  G R+  P    C   +Y LMLDCW+     RP F ++V  +  L
Sbjct:  221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDE---PPKMHCSAEGEWLVPIGKCMCKAGYEEKNG--TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVC------EKDYFRRESDPPTMA--CTRPPSAPRNA---ISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVN--GVSDLSP--GARQYVSVNVT------TNQAAPSPVTN-VKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYV-FQIRARTAAGYGVFSRRF-----EFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKA----KQDPEEEKMHFHNGHIKLPGVRTYIDPHT---YEDPNQAVH-------EFAKEIEASCITIERVIGAGEFGEVCSGRL-KLPGKR-ELPVAIKTLKVGYTEKQRRDFLGEASIMGQF-DHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQ-----------FTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP--MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKL 935          
The following BLAST results are available for this feature:
BLAST of TCONS_00005779-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
EPHA51.463e-6225.71Ephrin type-A receptor 5 OS=Homo sapiens GN=EPHA5 ... [more]
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