TCONS_00047908-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00047908-protein
Unique NameTCONS_00047908-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length898

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00047908-protein ID=TCONS_00047908-protein|Name=TCONS_00047908-protein|organism=Clytia hemisphaerica|type=polypeptide|length=898bp
NFRHSRHSNMNRINYLKRCYRLNIKRSYQSQGVTHGVLRSRLEKTTKQKD
PVIQNKEDAHNYLRKNSQFIATVDPLGLRGREDGIMSTIFKEFSSQEAEH
LKNTYCQNVAFDLEHLNDEDEKAWLYHQIENSLFELTKEKQKEICAHLLK
SQVFENFLAKRFPTLKRYSGEGAESMLAMFEELFHISSKSGTNEVMISIP
HRGRLALLTGMLNYPTKALFSKLKGNPEFHSSFRFIGDVSSHLTSSTDLN
YNDKNIHVTMVPNPSHLEASHPVIMGKARSRFLTKQQAYYNEENENSEDE
LLNILSIQVHGDAAMAGQGIVMETFALASLPHFEVGGSVHLVVNNQLGFT
TPHERASTAGHSSDIAKMISAPIIHVNGDSPEDVAKVTKLAVDYRNKFKK
DVVINMLCFRRWGHNELDDPTFTNPAMYDVIHQRESVPDLYKKKLVQDGV
VTETEIESIESEYYALLDEQLKDADRQVEPAWKPFEDNWKGIQQASHQSA
STWDTGCDIDLLKFVGARSTCFPDQFNIHQHLEKTFCEARMKKIESGENI
DWATAEALAIGSLLMQGHHVRISGQDVGRGTFSHRHSMLVDQKNNELYIP
LNHMSEQQSGCLEVVNSLLSEEAVLAYEYGMSIENPKHLVIWEAQFGDFF
NGAQIIIDTYIANAEAKWLLQSGLVMLLPHGMDGAGPDHSSSKIERFLQM
SDSKEDGVDSDDVNMQIVNPTTAAQYFHLLRRQQIRNFRKPLIVASPKLI
LRMSAASSTLSDLVPGTHFKPVIGDLSPGMDKIDTVVFCSGKHYYELAKQ
RTKQSKQNVAIIRLESLSPFPAEELKEEVKKYKNAQNFIWSQEEHRNQGA
WSFVSPRFQNILNVKLSYNGRPVLCASAIGVNKWHAQEVDDLTKSMFT
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_030484XLOC_030484Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00047908TCONS_00047908Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR005475Transketolase-like_Pyr-bd
IPR031717KGD_C
IPR0116032oxoglutarate_DH_E1
IPR001017DH_E1
IPR029061THDP-binding
Vocabulary: Molecular Function
TermDefinition
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0030976thiamine pyrophosphate binding
GO:0016624oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Vocabulary: Biological Process
TermDefinition
GO:0006099tricarboxylic acid cycle
GO:0055114oxidation-reduction process
GO:0008152metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0008152 metabolic process
biological_process GO:0055114 oxidation-reduction process
biological_process GO:0006099 tricarboxylic acid cycle
molecular_function GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
molecular_function GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity
molecular_function GO:0030976 thiamine pyrophosphate binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR005475Transketolase-like, pyrimidine-binding domainSMARTSM00861Transket_pyr_3coord: 550..753
e-value: 5.2E-49
score: 178.8
IPR005475Transketolase-like, pyrimidine-binding domainPFAMPF02779Transket_pyrcoord: 549..753
e-value: 1.6E-58
score: 197.2
IPR031717Multifunctional 2-oxoglutarate metabolism enzyme, C-terminalPFAMPF16870OxoGdeHyase_Ccoord: 758..897
e-value: 2.9E-46
score: 156.8
NoneNo IPR availableGENE3D3.40.50.970coord: 108..478
e-value: 1.3E-74
score: 250.8
NoneNo IPR availableGENE3D3.40.50.970coord: 546..765
e-value: 7.1E-54
score: 181.5
NoneNo IPR availableCDDcd02016TPP_E1_OGDC_likecoord: 154..428
e-value: 2.73899E-139
score: 416.93
IPR0116032-oxoglutarate dehydrogenase E1 componentTIGRFAMTIGR00239TIGR00239coord: 92..895
e-value: 2.8E-250
score: 830.9
IPR0116032-oxoglutarate dehydrogenase E1 componentPIRSFPIRSF000157Oxoglu_dh_E1coord: 23..898
e-value: 0.0
score: 1037.0
IPR001017Dehydrogenase, E1 componentPFAMPF00676E1_dhcoord: 186..480
e-value: 1.9E-48
score: 164.9
IPR029061Thiamin diphosphate-binding foldSUPERFAMILY52518Thiamin diphosphate-binding fold (THDP-binding)coord: 105..489
IPR029061Thiamin diphosphate-binding foldSUPERFAMILY52518Thiamin diphosphate-binding fold (THDP-binding)coord: 534..758

Blast
BLAST of TCONS_00047908-protein vs. Swiss-Prot (Human)
Match: DHTK1 (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial OS=Homo sapiens GN=DHTKD1 PE=1 SV=2)

HSP 1 Score: 910.212 bits (2351), Expect = 0.000e+0
Identity = 433/803 (53.92%), Postives = 573/803 (71.36%), Query Frame = 0
Query:  100 HLKNTYCQNVAFDLEHLNDEDEKAWLYHQIENSLFE-LTKEKQKEICAHLLKSQVFENFLAKRFPTLKRYSGEGAESMLAMFEELFHISSKSGTNEVMISIPHRGRLALLTGMLNYPTKALFSKLKGNPEFHSSFRFIGDVSSHLTSSTDLNYNDKN-IHVTMVPNPSHLEASHPVIMGKARSRFLTKQQAYYNEENENSEDELLNILSIQVHGDAAMAGQGIVMETFALASLPHFEVGGSVHLVVNNQLGFTTPHERASTAGHSSDIAKMISAPIIHVNGDSPEDVAKVTKLAVDYRNKFKKDVVINMLCFRRWGHNELDDPTFTNPAMYDVIHQRESVPDLYKKKLVQDGVVTETEIESIESEYYALLDEQLKDADRQVEPAWKPFEDNWKGIQQASHQSASTWDTGCDIDLLKFVGARSTCFPDQFNIHQHLEKTFCEARMKKIESGENIDWATAEALAIGSLLMQGHHVRISGQDVGRGTFSHRHSMLVDQKNNELYIPLNHMSEQQSGCLEVVNSLLSEEAVLAYEYGMSIENPKHLVIWEAQFGDFFNGAQIIIDTYIANAEAKWLLQSGLVMLLPHGMDGAGPDHSSSKIERFLQMSDSKEDGVDSDDVNMQIVNPTTAAQYFHLLRRQQIRNFRKPLIVASPKLILRMSAASSTLSDLVPGTHFKPVIGDLSPGMDKIDTVVFCSGKHYYELAKQRTK--QSKQNVAIIRLESLSPFPAEELKEEVKKYKNAQNFIWSQEEHRNQGAWSFVSPRFQNILNVKLSYNGRPVLCASAIGVNKWHAQEVDDLTKSMFT 898
            +L   YC  ++ +   L  +DEK W   + E    E  T E++K +   +L+SQ F++FLA +F T+KRY GEGAESM+  F EL  +S+ SG  +V+I +PHRGRL LLTG+L +P + +F K++G  EF  +F   GDV SHLTSS DL +   + +HVTM+PNPSHLEA +PV +GK R R  ++Q   Y+ +N     +   ++ +QVHGDA+  GQGIV ETF L++LPHF +GGSVHL+VNNQLG+TTP ER  ++ + SDI K++   IIHVNGDSPE+V + T+LA +Y+ +F+KDV+I++LC+R+WGHNELD+P +TNP MY +I  R+S+PD Y + L+  G++T+ E+  I+S YYA L++ L +      PA    + +W+G+ Q   Q  +TW TG  +DLL+FVG +S   P +  +H HL KT  ++RM+K+  G  +DWATAEALA+GSLL QG +VR+SGQDVGRGTFS RH+++V Q+ ++ YIPLNHM   Q G LEV NS LSEEAVL +EYGMSIE+PK L +WEAQFGDFFNGAQII DT+I+  EAKWLLQSG+V+LLPHG DGAGPDHSS +IERFLQM DS E+GVD D VNM +V+PTT AQYFHLLRRQ +RNFRKPLIVASPK++LR+ AA STL ++ PGT F PVIGD S    K+ T+VFCSGKH+Y L KQR      K + AIIR+E L PFP + L++E+ KYK+ ++ IWSQEE +N G WSFVSPRF+  L  KL   GRP L   A+G+   H  + +D+    F 
Sbjct:  121 YLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGD--RVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALN-LQAHWQGLAQPEAQ-ITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDILAKTFA 919          
The following BLAST results are available for this feature:
BLAST of TCONS_00047908-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
DHTK10.000e+053.92Probable 2-oxoglutarate dehydrogenase E1 component... [more]
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