TCONS_00048284-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00048284-protein
Unique NameTCONS_00048284-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length471

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00048284-protein ID=TCONS_00048284-protein|Name=TCONS_00048284-protein|organism=Clytia hemisphaerica|type=polypeptide|length=471bp
MDTESIIIKLFEIEAIKFGEFKLKTGILSPIYINLRVIIGYPKLLRQLSE
LLYKSASDGSSFDLTCGVPYTALPLATCMTLDHDIPMVIRRREAKDYGTR
QMIEGVYKSGDVCLIVEDVVTSGGSVLETAKELNNVDLIVKDAVVLLDRC
QGGKERLQENGIKLHSVMKLDQVLETLRKHNKIDQTLYNTVKQFLTTNQF
QPAKKDTPETLSYSARKDLVKNTVAKRILDIMETKKTNLAFSADITNCSE
LLKMVDLVGPHCCMVKTHVDILDDFNEEFVAKLKELSQKHNFIIFEDRKF
ADIGNTVKNQFSKGVYKINDWADLTNAHAVPGQGVIDGLESCTENMSRAC
LLIAQMSSAGALTDSKYIKSTVEMAKKKNDYVIGFISTSQVCTDDPRYLH
FTPGVSLQSSGDSLGQQYTSPEEVIRNRNCDVIIVGRGIYKAEDPVEAAK
AYQTAGYQAYLDKLDRMLNEE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_030731XLOC_030731Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00048284TCONS_00048284Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001754OMPdeCOase_dom
IPR004467Or_phspho_trans_dom
IPR000836PRibTrfase_dom
IPR013785Aldolase_TIM
IPR014732OMPdecase
IPR018089OMPdecase_AS
IPR023031OPRT
IPR011060RibuloseP-bd_barrel
IPR029057PRTase-like
Vocabulary: Molecular Function
TermDefinition
GO:0004590orotidine-5'-phosphate decarboxylase activity
GO:0004588orotate phosphoribosyltransferase activity
GO:0003824catalytic activity
Vocabulary: Biological Process
TermDefinition
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process
GO:0009116nucleoside metabolic process
GO:0044205'de novo' UMP biosynthetic process
GO:0006221pyrimidine nucleotide biosynthetic process
GO:0008152metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
biological_process GO:0044205 'de novo' UMP biosynthetic process
biological_process GO:0008152 metabolic process
biological_process GO:0009116 nucleoside metabolic process
biological_process GO:0006221 pyrimidine nucleotide biosynthetic process
molecular_function GO:0003824 catalytic activity
molecular_function GO:0004588 orotate phosphoribosyltransferase activity
molecular_function GO:0004590 orotidine-5'-phosphate decarboxylase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001754Orotidine 5'-phosphate decarboxylase domainSMARTSM00934OMPdecase_2coord: 238..452
e-value: 2.1E-34
score: 130.3
IPR001754Orotidine 5'-phosphate decarboxylase domainPFAMPF00215OMPdecasecoord: 237..452
e-value: 7.4E-67
score: 225.1
IPR004467Orotate phosphoribosyl transferase domainTIGRFAMTIGR00336TIGR00336coord: 10..172
e-value: 4.0E-36
score: 122.3
IPR000836Phosphoribosyltransferase domainPFAMPF00156Pribosyltrancoord: 43..155
e-value: 1.3E-6
score: 28.0
IPR000836Phosphoribosyltransferase domainCDDcd06223PRTases_typeIcoord: 50..167
e-value: 2.62666E-16
score: 74.3544
IPR013785Aldolase-type TIM barrelGENE3D3.20.20.70coord: 207..466
e-value: 3.1E-80
score: 268.7
IPR014732Orotidine 5'-phosphate decarboxylaseTIGRFAMTIGR01740TIGR01740coord: 239..453
e-value: 2.4E-59
score: 198.6
NoneNo IPR availableGENE3D3.40.50.2020coord: 1..204
e-value: 7.6E-35
score: 119.9
NoneNo IPR availableCDDcd04725OMP_decarboxylase_likecoord: 239..452
e-value: 1.57117E-51
score: 174.286
IPR018089Orotidine 5'-phosphate decarboxylase, active sitePROSITEPS00156OMPDECASEcoord: 294..307
IPR023031Orotate phosphoribosyltransferaseHAMAPMF_01208PyrEcoord: 1..239
score: 20.142
IPR011060Ribulose-phosphate binding barrelSUPERFAMILY51366Ribulose-phoshate binding barrelcoord: 211..463
IPR029057Phosphoribosyltransferase-likeSUPERFAMILY53271PRTase-likecoord: 6..197

Blast
[Close]
BLAST of TCONS_00048284-protein vs. Swiss-Prot (Human)
Match: UMPS (Uridine 5'-monophosphate synthase OS=Homo sapiens GN=UMPS PE=1 SV=1)

HSP 1 Score: 494.582 bits (1272), Expect = 5.185e-173
Identity = 237/469 (50.53%), Postives = 332/469 (70.79%), Query Frame = 0 
Query:    6 IIIKLFEIEAIKFGEFKLKTGILSPIYINLRVIIGYPKLLRQLSELLYKSASD-GSSFDLTCGVPYTALPLATCMTLDHDIPMVIRRREAKDYGTRQMIEGVYKSGDVCLIVEDVVTSGGSVLETAKELNNVDLIVKDAVVLLDRCQGGKERLQENGIKLHSVMKLDQVLETLRKHNKIDQTLYNTVKQFLTTNQFQPAK--------KDTPETLSYSARKDLVK-NTVAKRILDIMETKKTNLAFSADITNCSELLKMVDLVGPHCCMVKTHVDILDDFNEEFVAKLKELSQKHNFIIFEDRKFADIGNTVKNQFSKGVYKINDWADLTNAHAVPGQGVIDGLESCTENMSRACLLIAQMSSAGALTDSKYIKSTVEMAKKKNDYVIGFISTSQVCTDDPRYLHFTPGVSLQSSGDSLGQQYTSPEEVIRNRNCDVIIVGRGIYKAEDPVEAAKAYQTAGYQAYLDKL 464
            ++  L++++A KFG+F LK+G+ SPIYI+LR I+  P+LL Q++++L+++A + G SFD  CGVPYTALPLAT +   + IPM+IRR+E KDYGT++++EG    G+ CLI+EDVVTSG SVLET + L    L V DA+VLLDR QGGK++LQ +GI+LHSV  L ++LE L +  K+D      VK+F+  N F  A         K+ P+ LS+ AR +L + + VA ++L +M+ K+TNL  SAD++   ELL++ D +GP  CM+KTHVDIL+DF  + + +L  L++ H F+IFEDRKFADIGNTVK Q+  G++KI  WADL NAH VPG GV+ GL+     + R CLLIA+MSS G+L    Y ++ V MA++ +++V+GFIS S+V    P +LH TPGV L++ GD+LGQQY SP+EVI  R  D+IIVGRGI  A D +EAA+ Y+ A ++AYL +L
Sbjct:   11 LVTGLYDVQAFKFGDFVLKSGLSSPIYIDLRGIVSRPRLLSQVADILFQTAQNAGISFDTVCGVPYTALPLATVICSTNQIPMLIRRKETKDYGTKRLVEGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAHGIRLHSVCTLSKMLEILEQQKKVDAETVGRVKRFIQENVFVAANHNGSPLSIKEAPKELSFGARAELPRIHPVASKLLRLMQKKETNLCLSADVSLARELLQLADALGPSICMLKTHVDILNDFTLDVMKELITLAKCHEFLIFEDRKFADIGNTVKKQYEGGIFKIASWADLVNAHVVPGSGVVKGLQEVGLPLHRGCLLIAEMSSTGSLATGDYTRAAVRMAEEHSEFVVGFISGSRVSM-KPEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGKRGSDIIIVGRGIISAADRLEAAEMYRKAAWEAYLSRL 478
The following BLAST results are available for this feature:
BLAST of TCONS_00048284-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
UMPS5.185e-17350.53Uridine 5'-monophosphate synthase OS=Homo sapiens ... [more]
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