TCONS_00048912-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00048912-protein
Unique NameTCONS_00048912-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1432

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00048912-protein ID=TCONS_00048912-protein|Name=TCONS_00048912-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1432bp
MADQGVIVAHDSLLKHACHWTITAQNLSHNEIIYNTQSSDHNILLHITKL
KTSCFDSYLNIFDGVPPNPRTSSSIQNSPFKLLASLCGPDLDDKESYFRS
QTGVLTIVYEGNIISSQRTHPLNANDRGFQAIFQTLKCEDDCMAPFVCDV
SNECLCPTHLTGHHCQFKACPHDCNAATNQGICDQETKLCRCKFGFTGVD
CANESLPFHLQLHHLASLQLPEHSPFTMYGSSMEYYDNKLYLFGNTGLSD
SSGYFTVFDLNSTSWSSIDSGIDAQPNNRIFHCSFIFQDLMYIHGGVDKG
GPSDDLWTFNFTSSTWKQVPLKKSFDLDVRLSGHTCTKVELFVYLIGGYA
PSDGLSEFVYYIDLASHRINVIKFNDLEPVGIYLHVAIYDKETDYIYLHG
GVSFYDDEIKPSNQMYAFRPGNDPTWNYIEALPDDTVPTLVGHAAIKREE
DIYVLSGYDDLLGFNKEVYVWKFHCNRWFKYENENVTDTFDGLASIFASV
TLDNNNTFYVFTGYQPLSINGGELFSLLLPNKPCSLFDGLQTGCLKSFGC
RWCPANQSCADQSVPCENSTLSQQCNLNTMHSRGCDTFSTCSTCLSKYAQ
NNDRCHWCKCGKGAERVCLSNNQPCPCALSQGLSANMSIVECHKGPCYTS
TCMNCHNQCFWGTHFQYITETDRRYDDKGNLPYNCFTKVLVDHVVSHPGY
LKVKDQSEGQCPATCDTFKTCTACIASRGDLSGSTTCVWSEKLSQCMSTA
ILPLYCPIARCGSVSSTTCPVKGVCSRQQDCASCSQYTNCGWCSKGDQGY
GTCMEGDFLEPFNEICGSGLSSNGRVVDSGNSANYTWAYMQCPLENECTN
GHSNCTKSEVCRDLIEGYQCTCKVGYKRVKGLCEPVCDPECENGECVTPN
QCHCSFGWTGQQCNVSCMCNGHSNCLNETFPDVCLACQNDTQGAQCTRCK
PLFVGSPRDGGSCQTCQHFCNGNSDICLYQTQQQEVERLGISNNRSALLE
WITENVGDGPKFPSEAVCLMCGKLSSGETCDECVEGYYKDKKSNVCVKCN
CNGHGNVCNKDGLDCQCLHNTRSNTACEVDCQNDQCSKCIEKDDYIGNPV
SGNQCYKRINAKSSETVTLSGSNKLAFFAVAPSFTNVNIRINIDVLQGSL
ELFIADENQIFKLEMNGTQPRLTITRDTNRARRSMEASTNFLPSRSAFKD
RITTFENFETDILWIYNIEKRVVIKIDHTQHNLRTKKFYFVLLPTNKTGS
DTTKFHVYFRQDLPRIDLLLFFLVLSVILLFILSGFIIGMKVRIDFIRNT
QNQIQQLEMNAMQSRPLASYPLLFTKDDQKPHHAQSSFKNENRINKKKNE
KLRTKEARLVLPLAEQETEDGQAAIVSVVVQFPKNEISEWNCAIGSGLCQ
VQNQHLLHIRASESSSGGRKVQTIYHATQIHS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031074XLOC_031074Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00048912TCONS_00048912Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001881EGF-like_Ca-bd_dom
IPR016201PSI
IPR000742EGF-like_dom
IPR015915Kelch-typ_b-propeller
IPR013032EGF-like_CS
IPR002049Laminin_EGF
IPR000152EGF-type_Asp/Asn_hydroxyl_site
IPR000859CUB_dom
IPR011043Gal_Oxase/kelch_b-propeller
Vocabulary: Molecular Function
TermDefinition
GO:0005509calcium ion binding
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005509 calcium ion binding
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001881EGF-like calcium-binding domainSMARTSM00179egfca_6coord: 845..884
e-value: 0.0098
score: 18.0
IPR016201PSI domainSMARTSM00423psinew7coord: 584..643
e-value: 19.0
score: 2.8
coord: 774..843
e-value: 5.6
score: 8.4
coord: 714..770
e-value: 0.61
score: 18.3
IPR000742EGF-like domainSMARTSM00181egf_5coord: 847..884
e-value: 0.13
score: 21.3
coord: 169..202
e-value: 140.0
score: 3.0
coord: 924..964
e-value: 20.0
score: 12.6
coord: 137..166
e-value: 59.0
score: 7.2
coord: 886..914
e-value: 18.0
score: 13.1
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 134..166
score: 7.219
IPR000742EGF-like domainPROSITEPS50026EGF_3coord: 844..884
score: 9.212
NoneNo IPR availableGENE3D2.10.25.10coord: 1049..1107
e-value: 0.035
score: 14.0
NoneNo IPR availableGENE3D2.10.25.10coord: 843..893
e-value: 1.1E-5
score: 25.2
NoneNo IPR availableGENE3D2.10.25.10coord: 915..966
e-value: 4.3E-6
score: 26.5
NoneNo IPR availableGENE3D2.170.300.10coord: 110..207
e-value: 7.0E-5
score: 22.5
NoneNo IPR availableGENE3D2.10.25.10coord: 969..1048
e-value: 4.9E-6
score: 26.2
NoneNo IPR availablePFAMPF13418Kelch_4coord: 279..320
e-value: 6.6E-5
score: 22.7
NoneNo IPR availableCDDcd00055EGF_Lamcoord: 916..964
e-value: 0.00574402
score: 35.4078
NoneNo IPR availableCDDcd00055EGF_Lamcoord: 1049..1106
e-value: 0.00402675
score: 35.793
NoneNo IPR availableSUPERFAMILY57196EGF/Laminincoord: 917..967
IPR015915Kelch-type beta propellerGENE3D2.120.10.80coord: 211..368
e-value: 1.5E-24
score: 86.2
IPR015915Kelch-type beta propellerGENE3D2.120.10.80coord: 369..768
e-value: 3.5E-7
score: 28.9
IPR013032EGF-like, conserved sitePROSITEPS00022EGF_1coord: 902..913
IPR013032EGF-like, conserved sitePROSITEPS00022EGF_1coord: 154..165
IPR013032EGF-like, conserved sitePROSITEPS01186EGF_2coord: 870..883
IPR002049Laminin EGF domainPROSITEPS01248EGF_LAM_1coord: 1018..1051
IPR000152EGF-type aspartate/asparagine hydroxylation sitePROSITEPS00010ASX_HYDROXYLcoord: 861..872
IPR000859CUB domainPROSITEPS01180CUBcoord: 1..136
score: 10.694
IPR011043Galactose oxidase/kelch, beta-propellerSUPERFAMILY50965Galactose oxidase, central domaincoord: 227..511

Blast
BLAST of TCONS_00048912-protein vs. Swiss-Prot (Human)
Match: MEGF8 (Multiple epidermal growth factor-like domains protein 8 OS=Homo sapiens GN=MEGF8 PE=1 SV=2)

HSP 1 Score: 528.865 bits (1361), Expect = 1.754e-157
Identity = 419/1537 (27.26%), Postives = 646/1537 (42.03%), Query Frame = 0
Query:   52 TSCFDSYLNIFDGVPPNPRTSSSIQNSPFKLLASLCGPDLDDKESYFRSQTGVLTIVYEGNIISSQRTHPLNANDRGFQAIFQTLKCEDDCMAPFVCDVSNECL------------CPTHLTGHHCQFKACPHDCNAATNQGICDQETKLCRCKFGFTGVDCANESLPFHLQLHHLASLQLPEHSP---FTMYGSSM-EYYDNKLYLFGNTGLSDSSGYFTV-FDLNSTSWSSIDSGID---AQPNNRIFHCSFIF---QDLMYIHGGVDKGGPSDDLWTFNFTSSTWKQVPLKKSFDLDVRLSGHTCT-KVELFVYLIGGYAPSDGLSEFVYYIDLASHRINVIKFNDLEPVGIYLHVAIYDKETDYIYLHGGVSFYDDEIKPSNQMYAFR---------------------------------PGNDP-TWNYIE---------------ALPDDTVPTL------VGHAAIKREEDIYVLSGYDDLLGFNKEVYVWKFHCNRWFKYENENVTDTFDGLASIFASVTLDNNNTFYVFTGYQPLSINGGELFSLLLPNKPCSLFDGLQTGCLKSFGCRWCPANQSCADQS--VPCENSTLSQQCNLNTMHSRGCDTFSTCSTCLSKYAQ---------NNDRCHWC-KCGKGAERVCLSNNQPCP----CALSQGLSANMSIVECHKGPCYTSTCMNC--HNQCFWGTHFQYITETDRRYDDKGNLPYNCFTKVLVDHVVSHPGYLKVKDQSEGQCPATCDTFKTCTACIASRGDLSGSTTCVWSEKLSQCMSTAILPLYCPIARCGSVSSTTCPVKGVCSRQQDCASCSQYTNCGWCSKGDQ-GYGTCMEGDFLEPFNEI-CGSGLSSNGRVVDSGNSANYTWAYMQCPLENECTNGHSNCTKSEVCRDLIEGYQCTCKVGYK--RVKGLCEPVCDPECENGECVTPNQCHCSFGWTGQQCNVSCMCNGHSNCLNETFPDVCLACQNDTQGAQCTRCKPLFVGSPRDGGSCQTCQHFCNGNSDICLYQTQQQ--EVERLGISNNRSALLEWITENVGDGPKFPSEAVCLMCGKLSSGETCDECVEGYY-KDKKSNVCVKCNCNGHGNVCN-KDGLDCQCLHNTRSNT------ACEVDCQNDQCSKCIEKDDYIGNPVSGNQCYKRINAK-------SSETVTLS-------GSNKLAFFAVAPSFTNVNIRINIDVLQGSLELFIADENQIFKLEMNGTQPRLTITRDTNRARRSMEASTNFLPS----------------------RSAFKDRITTFENF--ETDILWIYNIEKRVVIKIDHTQHNLRTKKFYFVLLPT------NKTGSDTTKFHVYFRQDLPRIDLLLFFLVLSVILLFILSGFIIGMKVRIDFIRNTQNQIQQLEMNAMQSRPLASYPLLFTKDDQKPHHAQSSFKNENRINKKKNEKL-------------------------RTKEARLVLPLAEQETEDGQAAIVSVVVQFPKNEISEWNCAIGSGLCQVQNQHLLH 1408
            T C  SY+  FDG P      + +  S   L+A+ CG    D+    ++ +G+L + +E N  SS           GF A   + +C      P  C V  EC+            CP    G HC+   CP +CNA T  G C+Q   +C C  GF G DCA +     L    L   +L   +        G +M +  D  L++FG  GL          + ++   W+ + +G +     P+ R FH +      +  MY+ GG+  GG + D W  N T+  W+Q    ++ +L   ++GHT T +  L + L+GGY+P +G ++ +    LA+        +   P G+Y H A+Y + TD +Y+ GG  F+ +   PS ++Y+                                   PG  P +W + E                  ++  P L      + HA+    + + VL G  D   F+ +V +++ +CN W   +          +    A       +  Y+  G+  +++  G L +L LP  PC L    +  C +S  C WC       DQ+  + C  S     C+        C    TCS CL+++ +         +  RC WC  C +GA   C+  N  C     C ++Q          C +  C  + C  C    +C W   F+   ET R    +    + CF+  L++  VS    + V+      CP  C     CT+C+ S+G   G   CVWS  L QC+S + LPL C    CG +          C++   CA C +  +CGWC+ G Q G G CMEG    P + + CG                  +WA++ CP E+EC NGH +C +++ C D   GY+C+CK GY    + GLC PVC   C NG CV P+ C C FG+ G+ C+  C CN HS C      D CL C+N T+G+ C +C PLFVGS   GG+C+ C  FC GNS IC+ + + Q  + E    S +   +  W+TE   +      EAVC+ C   S GE C+ C++GY+  D K   C KC CNGH + CN +DG  C C +NT + T      +   DC   QC+KC  ++ + G+P+ G QCY+ I+ +       +S+T           G  +   F V P FTNV+IR+ +DV  G+++L+++     F + +       T+      A        +  P                       R  +   + T+      + +L +  +  R+VI   H  H L++ +FY +LL           GS  ++  ++FRQD   IDL +FF V        LS  ++  K +    +  + +    EM  M SRP A   + F  D   P  A           ++    L                          T       P+  + TEDG A + ++++Q P    +     +GS L  V  +H LH
Sbjct: 1334 TPCTLSYVLAFDGFPRF--LDTGVVQSDRSLIAAFCG-QRRDRPLTVQALSGLLVLHWEANGSSSW----------GFNASVGSARCGSG--GPGSCPVPQECVPQDGAAGAGLCRCPQGWAGPHCRMALCPENCNAHTGAGTCNQSLGVCICAEGFGGPDCATKLDGGQLVWETLMDSRLSADTASRFLHRLGHTMVDGPDATLWMFGGLGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGPGPSPRSFHAAAYVPAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKAPQTVELPA-VAGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTWVSGAQSGTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRGLGQVPGEQPGSWGFREVRKKMALWAALAGTGGFLEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLLPDLTRSASVGPPMEESVAHAVAAVGSRLYISGGFGGVAL--GRLLALTLPPDPCRLLSSPEA-CNQSGACTWCHGACLSGDQAHRLGCGGSP----CSPMPRSPEECRRLRTCSECLARHPRTLQPGDGEASTPRCKWCTNCPEGA---CIGRNGSCTSENDCRINQ--REVFWAGNCSEAACGAADCEQCTREGKCMWTRQFKRTGETRRILSVQPTYDWTCFSHSLLN--VSP---MPVESSPPLPCPTPCHLLPNCTSCLDSKGADGGWQHCVWSSSLQQCLSPSYLPLRCMAGGCGRLLRGPESCSLGCAQATQCALCLRRPHCGWCAWGGQDGGGRCMEGGLSGPRDGLTCGR--------------PGASWAFLSCPPEDECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCVNGSCVEPDHCRCHFGFVGRNCSTECRCNRHSECAGVGARDHCLLCRNHTKGSHCEQCLPLFVGSAVGGGTCRPCHAFCRGNSHICISRKELQMSKGEPKKYSLDPEEIENWVTEGPSE-----DEAVCVNCQNNSYGEKCESCLQGYFLLDGK---CTKCQCNGHADTCNEQDGTGCPCQNNTETGTCQGSSPSDRRDCYKYQCAKC--RESFHGSPLGGQQCYRLISVEQECCLDPTSQTNCFHEPKRRALGPGRTVLFGVQPKFTNVDIRLTLDVTFGAVDLYVSTSYDTFVVRVAPDTGVHTVHIQPPPAPPPPPPPADGGPRGAGDPGGAGASSGPGAPAEPRVREVWPRGLITYVTVTEPSAVLVVRGVRDRLVITYPHEHHALKSSRFYLLLLGVGDPSGPGANGSADSQGLLFFRQDQAHIDLFVFFSVFFSCFFLFLSLCVLLWKAKQALDQRQEQRRHLQEMTKMASRPFAKVTVCFPPDPTAPASAWKPAGLPPPAFRRSEPFLAPLLLTGAGGPWGPMGGGCCPPAIPATTAGLRAGPITLEPTEDGMAGVATLLLQLPGGPHAPNGACLGSAL--VTLRHRLH 2811          

HSP 2 Score: 100.908 bits (250), Expect = 4.461e-21
Identity = 107/390 (27.44%), Postives = 142/390 (36.41%), Query Frame = 0
Query:  692 DHVVSHPGYLKVKDQSEGQCPATCDTFKTCTACIASRGDLSGSTTCVWSEKLSQCMSTAILPLYCPIARC----GSVSSTTCPVKGVCSRQQDCASCSQYTNCGWCSKGDQG-YGTCMEGDFLEPFNEICGSGLSSNGRVVDSGNSANYTWAYMQCPLENECTNGHSNCTKSEVCRDLIEGYQCTCKVGYKRVKGL--CEPVCDPECENGECVTPNQ--CHCSFGWTGQ-------------QCNVSCMCNGHSNCLNETFPDVCLACQNDTQGAQCTRCKPLFVGSPRDGGSCQTCQHFCNGNSDICLYQTQQQEVERLGISNNRSALLEWITENVGDGPKFPSEAVCLMCGKLSSGETCDECVEGYYKDKKSNVCVKCNCNGHGNVCN 1059
            D   S  G  +   +S  +CP  C    TC  C+A+      S+ C W +    C   A      P   C     SV S   P    C     C  C Q   CGWC   D    G C++GDF  P      S     G  +     A   WAY +CP  +EC  G + C     C +    Y+C C+ GY+   G+  C   C  +C +G C  P    C C  GWT               +C+  C C+ HS+C  +  P  C  CQ+ T G  C RC+P   G+      C+ CQ  CNG+ D            R G  +N S L                      C   + G  C  C  GYY D ++       C G   + N
Sbjct:  927 DAACSRRGRGRGALKSPEECPPLCSQRLTCEDCLAN------SSQCAWCQSTHTCFLFAAYLARYPHGGCRGWDDSVHSE--PRCRSCDGFLTCHECLQSHECGWCGNEDNPTLGRCLQGDFSGPLGGGNCSLWVGEGLGLPVALPAR--WAYARCPDVDECRLGLARCHPRATCLNTPLSYECHCQRGYQG-DGISHCNRTCLEDCGHGVCSGPPDFTCVCDLGWTSDLPPPTPAPGPPAPRCSRDCGCSFHSHC-RKRGPGFCDECQDWTWGEHCERCRPGSFGNATGSRGCRPCQ--CNGHGD-----------PRRGHCDNLSGL--------------------CFCQDHTEGAHCQLCSPGYYGDPRAGGSCFRECGGRALLTN 1271          
The following BLAST results are available for this feature:
BLAST of TCONS_00048912-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MEGF81.754e-15727.26Multiple epidermal growth factor-like domains prot... [more]
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