TCONS_00049004-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049004-protein
Unique NameTCONS_00049004-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length905

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049004-protein ID=TCONS_00049004-protein|Name=TCONS_00049004-protein|organism=Clytia hemisphaerica|type=polypeptide|length=905bp
MTPIPSYDDGDSIQNYEVMEILGQGAFASAYRAFNRKTGQEVAIKKIDKT
KLQRGNMIKRVKNEVEIHCQLKHPSILEMYSFFEDSHYVYLVLELCHNGE
LQRYLKSSSNGLPEKDARKIILQVVIGLLYLHSHGILHRDLSLGNLLLTK
SMDVKIADFGLAAKLNMPSEKHYTMCGTPNYISPEIATRSPHGLESDVWS
LGCLLYTLLVGTPPFDTEAVKTTLNKVVLADYVIPEHVSHEARDLIQQLL
KKNPNDRITLAGILDHPFMKSTKTKGNYGVGSLDSGVSTLHTTTTANSLN
IFSSLSTASSSGNQMNYSESRGQNHLTKHPPSPPVRLRSSNRQNYSPQKS
IHQRSHEFRKSLDFQHDENRLVDRSSTNSILSSLRNEKPLFSQPSDSGLD
YQGQQRGLDLIGSSYQTSSNVIGSRQPDSNIIGSQQTNSSLIGSRVLREV
NGNREFGTVLPNQFQRSHSTSGKENSNPSKSYENKENDRHRSAGSTSSKP
DCKINPLNSERLRPIRQRTRNAVVSILENESVVLEFLQKKNGEDLVVEVL
IISNDGIKVTQFHPNGRQGVRLSDAPPPIDSSSAVSYAFSALPTKLWKKY
QYAEKFVRLVKMKTPKVTYYSDRTKFSLMENDPADFEAVFYDGSKISLSS
NTYKLIDSNGTNIKFNDDESSKVLSTPQLDLFQHAKECHSHCKELENAVG
KLNTLNSLDEGRTAASYFPLIIGRRPSTSTVTSANEKPSKPPEIKGYVRD
VKNATVSSPSAPVSVSVMSYDGTLLSDIKQTTPLRGTKMSQPALPSRPKG
PVRASSTSSLDRISEEKKTVDGGGSISVKECFMQGVGWASQLKSGEIQIQ
YNDGSQMKFHPTLLVVHHTNATGETNRYSKTDALPCHVKTKLAQLPNAIE
ELSEK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031128XLOC_031128Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049004TCONS_00049004Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000959POLO_box_dom
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008266Tyr_kinase_AS
IPR033696POLO_box_Plk4_C
IPR033699POLO_box_Plk4_1
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000959POLO box domainGENE3D3.30.1120.30coord: 833..905
e-value: 0.11
score: 12.4
IPR000959POLO box domainPROSITEPS50078POLO_BOXcoord: 832..905
score: 9.032
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 35..358
e-value: 3.1E-14
score: 50.0
NoneNo IPR availableGENE3D1.10.510.10coord: 113..405
e-value: 1.3E-59
score: 200.8
NoneNo IPR availableGENE3D3.30.200.20coord: 6..112
e-value: 3.6E-33
score: 113.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 457..509
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 384..403
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 778..821
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 310..359
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 418..437
NoneNo IPR availableSUPERFAMILY82615Polo-box domaincoord: 832..902
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 16..269
e-value: 7.6E-72
score: 241.7
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 16..269
score: 52.838
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 22..46
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 136..148
IPR033696Plk4, C-terminal polo-box domainCDDcd13116POLO_box_Plk4_3coord: 829..903
e-value: 1.166E-21
score: 89.957
IPR033699Plk4, first cryptic polo-box domainCDDcd13114POLO_box_Plk4_1coord: 506..612
e-value: 1.57445E-46
score: 161.664
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 13..348

Blast
[Close]
BLAST of TCONS_00049004-protein vs. Swiss-Prot (Human)
Match: PLK4 (Serine/threonine-protein kinase PLK4 OS=Homo sapiens GN=PLK4 PE=1 SV=3)

HSP 1 Score: 395.201 bits (1014), Expect = 1.103e-122
Identity = 173/282 (61.35%), Postives = 227/282 (80.50%), Query Frame = 0 
Query:   10 GDSIQNYEVMEILGQGAFASAYRAFNRKTGQEVAIKKIDKTKLQRGNMIKRVKNEVEIHCQLKHPSILEMYSFFEDSHYVYLVLELCHNGELQRYLKSSSNGLPEKDARKIILQVVIGLLYLHSHGILHRDLSLGNLLLTKSMDVKIADFGLAAKLNMPSEKHYTMCGTPNYISPEIATRSPHGLESDVWSLGCLLYTLLVGTPPFDTEAVKTTLNKVVLADYVIPEHVSHEARDLIQQLLKKNPNDRITLAGILDHPFMKSTKTKGNYGVGSLDSGVSTLH 291
            G+ I++++V  +LG+G+FA  YRA +  TG EVAIK IDK  + +  M++RV+NEV+IHCQLKHPSILE+Y++FEDS+YVYLVLE+CHNGE+ RYLK+      E +AR  + Q++ G+LYLHSHGILHRDL+L NLLLT++M++KIADFGLA +L MP EKHYT+CGTPNYISPEIATRS HGLESDVWSLGC+ YTLL+G PPFDT+ VK TLNKVVLADY +P  +S EA+DLI QLL++NP DR++L+ +LDHPFM    +  +  +G+++  + + H
Sbjct:    6 GEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGTVEDSIDSGH 287

HSP 2 Score: 221.09 bits (562), Expect = 6.581e-60
Identity = 142/403 (35.24%), Postives = 219/403 (54.34%), Query Frame = 0 
Query:  506 PLNSERLRPIRQRTRNAVVSILENESVVLEFLQKKNGEDLVVEVLIISNDGIKVTQFHPNGRQGVRLSDAPP-PIDSSSAVSYAFSALPTKLWKKYQYAEKFVRLVKMKTPKVTYYSDRTKFSLMENDP-ADFEAVFYDGSKISLSSNTYKLIDSNGTNIKFNDDESSKVLSTPQLDLFQHAKECHSHCKELENAVGKLNTLNSLDEGRT-AASYFPLIIGRRPSTSTVTSANEKPSKPPEI---------KGYVRDVKNATVSSPSAPV-SVSVMSYDGTLLSDIKQTTPLRGTKMSQPALPSRPKGPVRASSTSSLDRISEEKKTVDGGGSISVKECFMQGVGWASQLKSGEIQIQYNDGSQMKFHPTLLVVHHTNATGETNRYSKTDALPCHVKTKLAQL 895
            PL + RL+PIRQ+T+ AVVSIL++E V +E +++   ++ V EVL IS+DG  +T ++PNG +G  L+D PP P D+ S   Y+F  LP K W+KYQYA +FV+LV+ K+PK+TY++   K  LMEN P ADFE  FYDG KI  + +  ++I+  G +     +     L         HA E H  C  LE+ +       S +E +T +A +FP+IIGR+P +   TS+ +  S PP +           + R V ++  S   AP+ + S+++ +G  L     TT   GT +S  +L                      K  +     + +K  F++ VGWA+QL SG + +Q+NDGSQ+     +  + +T+  G+T RY + + LP ++K KL  L
Sbjct:  593 PLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKEVLQISSDGNTITIYYPNGGRGFPLADRPPSPTDNIS--RYSFDNLPEKYWRKYQYASRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDFIQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESII-------SEEERKTRSAPFFPIIIGRKPGS---TSSPKALSPPPSVDSNYPTRERASFNRMVMHSAASPTQAPILNPSMVTNEGLGL-----TTTASGTDISSNSL----------------------KDCLPKSAQL-LKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCL 955
The following BLAST results are available for this feature:
BLAST of TCONS_00049004-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PLK41.103e-12261.35Serine/threonine-protein kinase PLK4 OS=Homo sapie... [more]
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