TCONS_00049254-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049254-protein
Unique NameTCONS_00049254-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length822

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049254-protein ID=TCONS_00049254-protein|Name=TCONS_00049254-protein|organism=Clytia hemisphaerica|type=polypeptide|length=822bp
MYKLSIIVIIGLTIIPDLALSADKKIQIGLYNPDEDGKDRSVAATVLTAI
DVIKEQNKILKGYQIEAYLYYAQQHTFGSAVWAALNNLGLNLTNYPMELK
KAEANNQSKVRVNYQGPKEFGTTLNPIAMLGPRSTFDTRTMYPVYTTRNI
LHISFDAAGESLSVVKDYPYLFNSAPPVFLYVKALVQYLVHFNLDKIAFI
HYSDQSKSFNSNKLTADRFEREAAENGINIVYVGEIRFDEFTDKSQYSSY
FSNAFNAIKKNDIRVIVFSLTDEAMRTMICEAYRLGLYGSKYQFISILAE
GMTSWVKEWKTVNCSEETQRFMSRNIIGLSRSPREKVETITEVGLTKKEI
WTRIQNKMTEILSQPIPYDEWLAYVFDSVLAFALALDKILKRDPSFVENH
KVGTLDPARMNTMLNEIRQLDFIGASGRFKYKQDGDFLYRDGNIRYRKLK
FKGNETKSGLEAIGLFDKDTSKITMNFSQLYYKQIPRAGPEHIENIVLLP
QSVVYTMWILSGLGIIISLIFLTVNIYYRDVTYIKLSSPNINSLTCIGSI
LLYGAVICYGFDSRYVSEHSVAYMCNITTFMLSMGFTLTFGSLFSKTWRI
YRIFTRAEAARYVVIKDIHLFTVVFLMLVVDAVLCFTWMGVSPFTLTSQL
LSSLRDVKADTIENDIIHRCQCEYQSHFIFATFAYKGILMVFGLFVAYET
KRIKVAAINDSKHIGLAVYNVCLFSALGSIVVFCLYDTDRFQEGYIFFGA
CILEITTVTLCLVFVPKVLMLLTNFEDPNFKKGRPVFNPTAQPSADDTNT
NSQWSTTNSQCAMTTSTKSLNF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031269XLOC_031269Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049254TCONS_00049254Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000337GPCR_3
IPR002456GPCR_3_GABA_rcpt_B1
IPR001828ANF_lig-bd_rcpt
IPR017978GPCR_3_C
IPR028082Peripla_BP_I
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004965G-protein coupled GABA receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004965 G-protein coupled GABA receptor activity
molecular_function GO:0004930 G-protein coupled receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000337GPCR, family 3PRINTSPR00248GPCRMGRcoord: 583..604
score: 35.23
coord: 620..643
score: 20.18
NoneNo IPR availablePRINTSPR01176GABABRECEPTRcoord: 542..563
score: 39.26
coord: 709..732
score: 36.36
coord: 503..526
score: 33.33
coord: 624..649
score: 27.62
coord: 594..611
score: 34.34
coord: 575..594
score: 40.0
coord: 169..188
score: 25.0
NoneNo IPR availableGENE3D3.40.50.2300coord: 24..437
e-value: 5.9E-25
score: 87.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 791..822
IPR002456GPCR family 3, gamma-aminobutyric acid receptor, type B1PRINTSPR01177GABAB1RECPTRcoord: 371..389
score: 36.84
coord: 544..565
score: 36.36
coord: 502..527
score: 34.62
coord: 713..735
score: 30.43
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 43..438
e-value: 1.3E-34
score: 119.8
IPR017978GPCR family 3, C-terminalPFAMPF000037tm_3coord: 515..769
e-value: 3.9E-45
score: 154.4
IPR017978GPCR family 3, C-terminalPROSITEPS50259G_PROTEIN_RECEP_F3_4coord: 510..776
score: 24.333
IPR028082Periplasmic binding protein-like ISUPERFAMILY53822Periplasmic binding protein-like Icoord: 24..91
coord: 124..439

Blast
BLAST of TCONS_00049254-protein vs. Swiss-Prot (Human)
Match: GABR2 (Gamma-aminobutyric acid type B receptor subunit 2 OS=Homo sapiens GN=GABBR2 PE=1 SV=1)

HSP 1 Score: 249.98 bits (637), Expect = 1.556e-70
Identity = 179/672 (26.64%), Postives = 323/672 (48.07%), Query Frame = 0
Query:  149 NILHISFDAAGESLSVVKDYPYLFNSAPPVFLYVKALVQYLVHFNLDKIAFIHYSDQSKSFNSNKLTADRFEREAAENGINIVYVGEIRFDEFTDKSQYSSYFSNAFNAIKKNDIRVIVFSLTDEAMRTMICEAYRLGLYGSKYQFISILAEGMTSWVKEWKTVNCSEETQRFMSRNI-------IGLSRSPREKVETITEVGLTKKEIWTRIQNKMTEILSQPIPYDEWLAYVFDSVLAFALALDKILKRDPSFVENHKVGTL---DPARMNTMLNEIRQLDFIGASGRFKYKQDGDFLYRDGNIRYRKLKFKGNETKSG-LEAIGLFDKDTSKITMNFSQLYYKQIPRAGPEHIENIVLLPQSVVYTMWILSGLGIIISLIFLTVNIYYRDVTYIKLSSPNINSLTCIGSILLYGAVICYGFDSRYVSEHSVAYMCNITTFMLSMGFTLTFGSLFSKTWRIYRIFTRAEAARYVVIKDIHLFTVVFLMLVVDAVLCFTWMGVSPFTLTSQLLSSLRDVKADTIE-NDIIHRCQCEYQSHFIFATFAYKGILMVFGLFVAYETKRIKVAAINDSKHIGLAVYNVCLFSALGSIVVFCLYDTDRFQEGYIFFGACILEITTVTLCLVFVPKVLMLLTNFEDPNFKKGRPVFNPTAQPSADDTNTNSQWSTTN 808
            N++ +SF A    L+  K YPY F + P       A+++ L H+   ++  +    Q  S   N LT              ++Y  +I   E +D   +S+    +   +K ND+R+I+          + C AY   +YGSKYQ+I I      SW   W+ V+    + R + +N+       IG+   P    +  T  G T ++      NK + +        ++  Y +D +   A  L + ++   +   + ++      D      +LN + + +F G +G+  ++ +G+   R G I++ + +    E K G   A+     DT +I  +  +    + P+     +E +  +   +   +  L+ LG+I++  FL  NI  R+   IK+SSP +N+L  +G +L Y ++  +G D  +VSE +   +C + T++L++G+T  FG++F+KTWR++ IF   +  +  +IKD  L  +V  ML++D  +   W  V P   T +  S   D     I    ++  C+  + + ++   +AYKG+LM+FG F+A+ET+ + + A+NDSK+IG++VYNV +   +G+ V F   D    Q  +      I+  +T+TLCLVFVPK++ L TN   P+       F  T     +D+ T++  ++ N
Sbjct:  150 NLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTG-------------VLYGEDI---EISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWI-IPGWYEPSW---WEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGP-----SKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFR-NGE---RMGTIKFTQFQ-DSREVKVGEYNAVA----DTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKK-IIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQ--FCIVALVIIFCSTITLCLVFVPKLITLRTN---PDAATQNRRFQFTQNQKKEDSKTSTSVTSVN 781          
The following BLAST results are available for this feature:
BLAST of TCONS_00049254-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GABR21.556e-7026.64Gamma-aminobutyric acid type B receptor subunit 2 ... [more]
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