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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00049754-protein ID=TCONS_00049754-protein|Name=TCONS_00049754-protein|organism=Clytia hemisphaerica|type=polypeptide|length=684bp
MKVISCCYKTSGRRRSSKMVDTTSSNKNDILNTLKRRGALKEPKLFIVMQ
HKFIPHYFKEPTYCAHCKSFIWGVVGNNGYQCKVCSFGVHKRCHEYVSFK
CPGADTGPDDAPQNPHRFKVHTYGSPTFCDHCGTLLYGLFKQGLKCQACD
MNVHKRCEQSGCIPKLCGADHTEKRGRIQVKIFFEPKAKDEGRLTVQIKE
AKNLIPMDPTGMSDPYVKIKLQPHKKKTKIMKKNLNPTWGETFSFDITPA
EKDKRLSVEVWDYDFATSNDFMGSMSFGISELLKEPIEGWFKLLNQEEGE
FYNVPIQDDAAVAALAKKFQFMSPSERDNIQAPPTTPHQPPQEVISDMER
FKLEDFTFLKVIGKGSFGKVMLAEKKGSDRVYAIKILKKDVVLQNDDLEC
VMTEKRVLALQGKPPFLTALQSCFTTQDRLYFVMEFVNGGDLMFHIQQVG
KFKEPQAVFYAAEIVEGLLFLHKRGIIYRDLKLDNVLLDQSGHIKIADFG
MCKENIFAPKTTRTFCGTPDYIAPEIIAYQPYGASVDWWALGVLIYEMLA
GQPPFDGEDEDELFNSVLEQTVSFPRSLSREAISIIKGFLTKNPSRRLGS
GETGEQDIRDHQFFKYIDWVKLYKMEIQPPYKPKVKSKRSHDNFDPEFTE
EATRLTPIDRNFIQHVDQRVFENFSYINNTFVGQ Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
| GO:0035556 | intracellular signal transduction |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0005524 | ATP binding |
| GO:0004672 | protein kinase activity |
| GO:0008270 | zinc ion binding |
| GO:0004697 | protein kinase C activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
| molecular_function |
GO:0004697 |
protein kinase C activity |
| molecular_function |
GO:0004674 |
protein serine/threonine kinase activity |
| molecular_function |
GO:0008270 |
zinc ion binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR000008 | C2 domain | PRINTS | PR00360 | C2DOMAIN | coord: 233..246
score: 51.08
coord: 256..264
score: 57.36
coord: 209..221
score: 57.96 |
| IPR000008 | C2 domain | SMART | SM00239 | C2_3c | coord: 193..291
e-value: 2.0E-26
score: 103.8 |
| IPR000008 | C2 domain | PFAM | PF00168 | C2 | coord: 192..293
e-value: 4.3E-29
score: 100.7 |
| IPR000008 | C2 domain | GENE3D | 2.60.40.150 | | coord: 175..304
e-value: 5.7E-40
score: 135.7 |
| IPR000008 | C2 domain | PROSITE | PS50004 | C2 | coord: 193..276
score: 19.795 |
| IPR000008 | C2 domain | SUPERFAMILY | 49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | coord: 172..297 |
| IPR020454 | Diacylglycerol/phorbol-ester binding | PRINTS | PR00008 | DAGPEDOMAIN | coord: 64..73
score: 53.96
coord: 90..102
score: 38.69
coord: 48..62
score: 36.77
coord: 78..89
score: 42.9 |
| IPR000961 | AGC-kinase, C-terminal | SMART | SM00133 | pkinase_C_6 | coord: 615..678
e-value: 4.5E-22
score: 89.3 |
| IPR000961 | AGC-kinase, C-terminal | PROSITE | PS51285 | AGC_KINASE_CTER | coord: 615..684
score: 15.742 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SMART | SM00109 | c1_12 | coord: 116..167
e-value: 3.0E-12
score: 56.7
coord: 51..101
e-value: 7.4E-12
score: 55.4 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PFAM | PF00130 | C1_1 | coord: 51..103
e-value: 4.2E-15
score: 55.3
coord: 116..159
e-value: 2.2E-13
score: 49.8 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 116..167 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 50..101
score: 15.256 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 115..167
score: 14.577 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 116..167
e-value: 2.07792E-14
score: 67.9023 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 51..101
e-value: 2.22357E-14
score: 67.9023 |
| IPR000719 | Protein kinase domain | SMART | SM00220 | serkin_6 | coord: 356..614
e-value: 7.7E-104
score: 361.0 |
| IPR000719 | Protein kinase domain | PFAM | PF00069 | Pkinase | coord: 357..612
e-value: 9.2E-67
score: 225.1 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 356..614
score: 49.587 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 113..174
e-value: 1.6E-20
score: 72.2 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 453..670
e-value: 4.6E-60
score: 202.3 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 322..452
e-value: 2.6E-24
score: 84.9 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 48..112
e-value: 1.1E-20
score: 72.8 |
| None | No IPR available | CDD | cd05587 | STKc_cPKC | coord: 359..678
e-value: 0.0
score: 651.38 |
| None | No IPR available | CDD | cd04026 | C2_PKC_alpha_gamma | coord: 175..305
e-value: 9.84272E-68
score: 218.67 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 110..160 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 35..102 |
| IPR017892 | Protein kinase, C-terminal | PFAM | PF00433 | Pkinase_C | coord: 635..676
e-value: 1.5E-6
score: 28.7 |
| IPR014375 | Protein kinase C, alpha/beta/gamma types | PIRSF | PIRSF000550 | PKC_alpha | coord: 15..684
e-value: 0.0
score: 1086.6 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 362..385 |
| IPR008271 | Serine/threonine-protein kinase, active site | PROSITE | PS00108 | PROTEIN_KINASE_ST | coord: 476..488 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 332..657 |
Blast
BLAST of TCONS_00049754-protein vs. Swiss-Prot (Human)
Match: KPCA (Protein kinase C alpha type OS=Homo sapiens GN=PRKCA PE=1 SV=4) HSP 1 Score: 865.529 bits (2235), Expect = 0.000e+0 Identity = 418/670 (62.39%), Postives = 513/670 (76.57%), Query Frame = 0
Query: 21 DTTSSNKNDILNTLKRRGALKEPKLFIVMQHKFIPHYFKEPTYCAHCKSFIWGVVGNNGYQCKVCSFGVHKRCHEYVSFKCPGADTGPD-DAPQNPHRFKVHTYGSPTFCDHCGTLLYGLFKQGLKCQACDMNVHKRCEQSGCIPKLCGADHTEKRGRIQVKIFFEPKAKDEGRLTVQIKEAKNLIPMDPTGMSDPYVKIKLQP-----HKKKTKIMKKNLNPTWGETFSFDITPAEKDKRLSVEVWDYDFATSNDFMGSMSFGISELLKEPIEGWFKLLNQEEGEFYNVPI--QDDAAVAALAKKFQFMSPSERDNIQAPPTTPHQPPQEVISDMERFKLEDFTFLKVIGKGSFGKVMLAEKKGSDRVYAIKILKKDVVLQNDDLECVMTEKRVLALQGKPPFLTALQSCFTTQDRLYFVMEFVNGGDLMFHIQQVGKFKEPQAVFYAAEIVEGLLFLHKRGIIYRDLKLDNVLLDQSGHIKIADFGMCKENIFAPKTTRTFCGTPDYIAPEIIAYQPYGASVDWWALGVLIYEMLAGQPPFDGEDEDELFNSVLEQTVSFPRSLSREAISIIKGFLTKNPSRRLGSGETGEQDIRDHQFFKYIDWVKLYKMEIQPPYKPKVKSKRSHDNFDPEFTEEATRLTPIDRNFIQHVDQRVFENFSYINNTFV 682
D+T+S D+ N R+GAL++ + V HKFI +FK+PT+C+HC FIWG G G+QC+VC F VHKRCHE+V+F CPGAD GPD D P++ H+FK+HTYGSPTFCDHCG+LLYGL QG+KC CDMNVHK+C + +P LCG DHTEKRGRI + + + DE +L V +++AKNLIPMDP G+SDPYVK+KL P K+KTK ++ LNP W E+F+F + P++KD+RLSVE+WD+D T NDFMGS+SFG+SEL+K P GW+KLLNQEEGE+YNVPI D+ L +KF+ N P+ + P ++++R KL DF FL V+GKGSFGKVMLA++KG++ +YAIKILKKDVV+Q+DD+EC M EKRVLAL KPPFLT L SCF T DRLYFVME+VNGGDLM+HIQQVGKFKEPQAVFYAAEI GL FLHKRGIIYRDLKLDNV+LD GHIKIADFGMCKE++ TTRTFCGTPDYIAPEIIAYQPYG SVDWWA GVL+YEMLAGQPPFDGEDEDELF S++E VS+P+SLS+EA+S+ KG +TK+P++RLG G GE+D+R+H FF+ IDW KL EIQPP+KPKV K + +NFD FT LTP D+ I ++DQ FE FSY+N FV
Sbjct: 9 DSTASQ--DVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF-GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVIN--VPSLCGMDHTEKRGRI----YLKAEVADE-KLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPS---NNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGA-ENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFV 664
The following BLAST results are available for this feature:
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