TCONS_00051193-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00051193-protein
Unique NameTCONS_00051193-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1883

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00051193-protein ID=TCONS_00051193-protein|Name=TCONS_00051193-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1883bp
MQDTKVKLGFLKKFLEKILSERDLKKKDYAQLKKLCEETLDKVGNVSGGE
SEDADLEQFFPAIEMACQQTKSPKIVCSALDCLQKMIAYGYTNGPDSQRP
GKQIIDKIIETVCGCFNGTLTDEGVQLQIIKALLTAVTSPACEVHEGTLL
QSVRTCYNIYLASKNLINQTTAKATLTQMISVIFVKMEAQGNVGQTNNLV
VSEPSGEAPEPQKPSEHQETNENVDVTVNGEASDKNDDDRVDQNESSINT
QDSDSGIEVKAAITENNENQVEENIVTTDNTSHQEIENSDSAPLQSPKSL
KELSDHVVRSNSASSPDDDGESSGSTNKGDEDGSEFANFESAFPEAEEIK
TEQSEKQEEAKQDEGHEDASEKKADDENSNDSTSKEAPPETDNTSLPPSE
ETDNESVKQDDDAQTVVSEDGVESANYAKSAVSFPHILQKDAFLVFRSLC
KLSMKQLPDAPYDPKSHELRSKVLSLELLLACLQNAGEVFKTSEMFISAI
KQYLCVALSKNGVSSIPQVFELSLSLFLTLLSDFKTHLKMQIEVFFREIF
LNILETSTSSFQHKWMVMQALTKICQDAQTVVDVYVNYDCDLQSANIFER
LVYDLSKIAQGRHAMELGATPAQEKKIRVIGIECLVSILKCMVTWSKDLY
MNPYNQVSHTPEGGLLDKPDSKPSSTLEENSHGGSQQSLNSTNTVSSASD
NPEQIIVQKQRKELVEEGIKRFNNKSPMKGVKYLQEQGLLESTPIAVAEF
VMSDDRLDKTMVGELLGDFSDFAKEVMYRYVDMMDFEGVDFVSSLRMFLE
NFRLPGEAQKIDRLMEKFASRYCECNIEDEVFTSADAAYVLAYSIIMLTT
DLHSSQVKRKMTKEQYITMNRGINDGKDLPQEYLEAIYEDIQENEIQMKH
PQKAQNQRPATLFLMTEKQRRMLYLQEMESMAQIAKSMMEDISHVQTSFI
QATHIQHAKPMFKIAWTPVLAAFSIGLQDNEDANLINLCLDGMRCAIRIS
CIFQLQLERDAYIQALCQFSMLMANAVITEMKAKNIDTIKTLISVAYTDG
NYLAHSWLEIMQCISHLELLQLIGTGIRPRYVTGGSSNAPVVNVGGLAGS
ASTGLQSNGVIDSKKFSSIQESMGETSSQSVVVAVDRIFTGSIRLDGDAI
VDFVTALVSVSQDELVAPSQPRMYSLQKIVEIAYYNMGRIRLQWSRIWNV
LGDYFNKVGCSPNEEIAFFCVDSLRQLSMKFLEKGELSNFHFQKDFLRPF
EYIMKKSGSSTIRDMVVRCVAQMVNSQAKNIKSGWKNVFSVFHLAASDLD
EGIVELAFQTTAIIFEKHFSATVDSFQDAVKCLSEFACNAAFPDTSMEAI
RLIRHCAKHVYENPNMFKEHFAEDAGISDTDRVWVRGWFPVIFELSCIIN
RCKLDVRTRALTVMFEILKIYGHTYHKHWWKEVFKVVFRIFDGMKLPDLS
IEWAEKAEWMTTTCNHALYAIIDVFTQYFEDLADVLLDDMYGHLVWCVKQ
DNEQLARSGVNCLENLVVSNGQKFTPEIWTKTTKCIRLIFESSVPHNLIS
WKPENYTPPEHPVGTPTHHAKSPSTPSGTGHVRRPSRTPSRLTVDSVPEG
DFHYDVSEGDDISLHNFPQYPAHLQRFDSNTSLNAITRQKISPEKTMFNS
MLIKCVVQLELIQTIDNIVFFPTTSKKEDADNMAAAQAFFDNIFPEGNFK
STEAEQVSSLLDVGMFPHLSSEQLLLFATCLHEAHIFARDFNCNYEQRNL
LLKAGFTKGKSLPNLLKQETTSLASLLRILFRIYSEESRQEAWESVEEKL
KRVTAEAFEYFHNLESSSHRKAWTSVLVLILTKLLKLDDQRFSRHVNSFY
SRLCDLLVHELESELRVVIRKIFLRFGQVHSVS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_032445XLOC_032445Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00051193TCONS_00051193Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000904Sec7_dom
IPR032629DCB_dom
IPR023394Sec7_alpha_orthog
IPR011989ARM-like
IPR032691Sec7_N
IPR015403Sec7_C
IPR016024ARM-type_fold
Vocabulary: Biological Process
TermDefinition
GO:0032012regulation of ARF protein signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005086ARF guanyl-nucleotide exchange factor activity
GO:0005488binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0032012 regulation of ARF protein signal transduction
molecular_function GO:0005086 ARF guanyl-nucleotide exchange factor activity
molecular_function GO:0005488 binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000904Sec7 domainSMARTSM00222sec7_5coord: 708..896
e-value: 4.9E-91
score: 318.4
IPR000904Sec7 domainPFAMPF01369Sec7coord: 711..896
e-value: 2.3E-65
score: 219.7
IPR000904Sec7 domainPROSITEPS50190SEC7coord: 704..894
score: 42.148
IPR000904Sec7 domainSUPERFAMILY48425Sec7 domaincoord: 702..898
IPR032629Mon2, dimerisation and cyclophilin-binding domainPFAMPF16213DCBcoord: 25..189
e-value: 1.3E-31
score: 109.5
IPR023394Sec7 domain, alpha orthogonal bundleGENE3D1.10.1000.11coord: 786..906
e-value: 1.6E-47
score: 159.7
IPR011989Armadillo-like helicalGENE3D1.25.10.10coord: 1037..1552
e-value: 2.6E-24
score: 85.0
IPR011989Armadillo-like helicalGENE3D1.25.10.10coord: 8..651
e-value: 1.5E-7
score: 30.1
IPR032691Guanine nucleotide exchange factor, N-terminalPFAMPF12783Sec7_Ncoord: 439..597
e-value: 5.9E-49
score: 165.9
NoneNo IPR availableGENE3D1.10.220.20coord: 690..785
e-value: 7.5E-25
score: 86.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 197..257
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 660..702
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 278..421
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1555..1598
NoneNo IPR availableCDDcd00171Sec7coord: 711..896
e-value: 3.79261E-82
score: 268.707
IPR015403Sec7, C-terminalPFAMPF09324DUF1981coord: 1230..1311
e-value: 1.0E-34
score: 118.1
IPR016024Armadillo-type foldSUPERFAMILY48371ARM repeatcoord: 31..154
coord: 510..645
coord: 1198..1542
coord: 707..726

Blast
BLAST of TCONS_00051193-protein vs. Swiss-Prot (Human)
Match: BIG1 (Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens GN=ARFGEF1 PE=1 SV=2)

HSP 1 Score: 2030.76 bits (5260), Expect = 0.000e+0
Identity = 1098/1960 (56.02%), Postives = 1344/1960 (68.57%), Query Frame = 0
Query:    5 KVKLGFLKKFLEKILSERDLKKKDYAQLKKLCEETLDKV-----------GNVSGGESE-----------DADLEQFFPAIEMACQQTKSPKIVCSALDCLQKMIAYGYTNG--PDSQRPGKQIIDKIIETVCGCFNGTLTDEGVQLQIIKALLTAVTSPACEVHEGTLLQSVRTCYNIYLASKNLINQTTAKATLTQMISVIFVKMEAQG----------NVGQTNNLVVSEPSGEAPE-------PQKPSEHQETNENVDVTVNGEASDKN-DDDRVDQNESSINTQDSDSGIEVKAAITENNENQVEENIVTTDNTSHQEIENSDSAPLQSPKSLKELSDHVVRSNSASSPDDDGESSGSTNKGDEDGSEFANFESAFPEAEEIKTEQSEKQEEAKQDEGHEDASEKKADDENSNDSTSKEAPPETDNT-SLPPSEETDNESVKQDDDAQTVVSEDGVESANYA--KSAVSFPHILQKDAFLVFRSLCKLSMKQLPDAPYDPKSHELRSKVLSLELLLACLQNAGEVFKTSEMFISAIKQYLCVALSKNGVSSIPQVFELSLSLFLTLLSDFKTHLKMQIEVFFREIFLNILETSTSSFQHKWMVMQALTKICQDAQTVVDVYVNYDCDLQSANIFERLVYDLSKIAQGRHAMELGATPAQEKKIRVIGIECLVSILKCMVTWSKDLYMNPYNQVSHTPEGGLLDKPDSKPSSTL---EENSHGGSQQSLNST--------NTVSSASDNPEQIIVQKQRKELVEEGIKRFNNKSPMKGVKYLQEQGLLESTPIAVAEFVMSDDRLDKTMVGELLGDFSDFAKEVMYRYVDMMDFEGVDFVSSLRMFLENFRLPGEAQKIDRLMEKFASRYCECNIEDEVFTSADAAYVLAYSIIMLTTDLHSSQVKRKMTKEQYITMNRGINDGKDLPQEYLEAIYEDIQENEIQMKH------PQKAQNQRPATLFLMTEKQRRMLYLQEMESMAQIAKSMMEDISHVQTSFIQATHIQHAKPMFKIAWTPVLAAFSIGLQDNEDANLINLCLDGMRCAIRISCIFQLQLERDAYIQALCQFSMLMANAVITEMKAKNIDTIKTLISVAYTDGNYLAHSWLEIMQCISHLELLQLIGTGIRPRYV-----------TGGSSNAPVVNVG-GLAGSASTGLQSNGVIDSKKFSSIQESMGETSSQSVVVAVDRIFTGSIRLDGDAIVDFVTALVSVSQDELVAPSQPRMYSLQKIVEIAYYNMGRIRLQWSRIWNVLGDYFNKVGCSPNEEIAFFCVDSLRQLSMKFLEKGELSNFHFQKDFLRPFEYIMKKSGSSTIRDMVVRCVAQMVNSQAKNIKSGWKNVFSVFHLAASDLDEGIVELAFQTTA----IIFEKHFSATVDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKHVYENPNMFKEHFAEDAGISDTDRVWVRGWFPVIFELSCIINRCKLDVRTRALTVMFEILKIYGHTYHKHWWKEVFKVVFRIFDGMKLPDLSIEWAEKAEWMTTTCNHALYAIIDVFTQYFEDLADVLLDDMYGHLVWCVKQDNEQLARSGVNCLENLVVSNGQKFTPEIWTKTTKCIRLIFESSVPHNLISWKP---ENYTPPEHPVGTPTHHAKSPSTPSGTGHVRRPSRTPSRLTVDSVPEGDFHYDVSEGDDISLHNFPQYPAHLQRFDSNTSLNAITRQKISPEKTMFNSMLIKCVVQLELIQTIDNIVFFPTTSKKEDADNMAAAQAFFDNIFPEGNFKSTEAEQVSSLLDVGMFPHLSSEQLLLFATCLHEAHIFARDFNCNYEQRNLLLKAGFTKGKSLPNLLKQETTSLASLLRILFRIYSEESRQEAWESVEEKLKRVTAEAFEYFHNLESSSHRKAWTSVLVLILTKLLKLDDQRFSRHVNSFYSRLCDLLVHELESELRVVIRKIFLRFGQVHSVS 1883
            K K  FL + LEKIL+++++KK  ++QL+K CE  L+++           G    G S            +AD  ++F   E+ACQ +K P+IV ++LDCLQK+IAYG+  G  PDS  PGK++ID+IIET+CGCF G  TDEGVQLQIIKALLTAVTS   E+HEGT+LQ+VRTCYNIYLASKNLINQTTAKATLTQM++VIF +ME Q              Q ++L+ S  S   PE       P +  +H       D+ ++    DK+  DD   +N S I++ +++     +A   E     + +N V  D  +H    + +  P       +++  ++V         D GE  G+T     DG+              I T               ED S    D EN   +     P     T SLP             DD  +V S D  ES N +       F HILQKDAFLVFRSLCKLSMK L D P DPKSHELRSK+LSL+LLL+ LQNAG +F+T+EMFI+AIKQYLCVALSKNGVSS+P+VFELSLS+FLTLLS+FKTHLKMQIEVFF+EIFL ILETSTSSF HKWMV+Q LT+IC DAQ+VVD+YVNYDCDL +ANIFERLV DLSKIAQGR + ELG +  QE  +R  G+ECLVSILKCMV WSKD Y+NP +Q +   E     KP  +  S +   E  +  GS  SL ST        +T  S +DNPEQ  V KQ+KE++E+GI  FN K P +G++YLQEQG+L +TP  +A+F+  ++RLD T VGE LGD   F KEVMY YVD  DF G DFVS+LRMFLE FRLPGEAQKIDRLMEKFA+RY ECN    +F SAD AYVLAYSIIMLTTDLHS QVK KMTKEQYI MNRGIND KDLP+EYL AIY +I   +I MK       P K+  Q  A     +EKQRR+LY  EME MA+ AK++ME +SHVQ  F  ATH++H +PMFK+AWTP LAAFS+GLQD +D  + +LCL+G+RCAIRI+CIF +QLERDAY+QAL +F++L  ++ ITEMK KNIDTIKTLI+VA+TDGNYL +SW EI++CIS LEL QLIGTG++PRY+           TG    AP   VG GL G         G +D K+ +SIQES+GETSSQSVVVAVDRIFTGS RLDG+AIVDFV  L +VS DEL++ + PRM+SLQKIVEI+YYNMGRIRLQWSRIW V+GD+FNKVGC+PNE++A F VDSLRQLSMKFLEKGEL+NF FQKDFLRPFE+IMK++ S TIRDMVVRC+AQMVNSQA NI+SGWKN+FSVFHLAASD DE IVELAFQTT     ++FEKHF AT+DSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAK+V + P  FKE+ ++D  ++  DRVWVRGWFP++FELSCIINRCKLDVRTR LTVMFEI+K YGHTY KHWW+++F++VFRIFD MKLP+   +  EKAEWMTTTCNHALYAI DVFTQY E L+DVLLDD++  L WCV+QDNEQLARSG NCLEN+V+ NG+KFT EIW KT  C   IF++++PH L++W+P   E   PP  PV                    +P  T S+ +V      D H  +      S+ N PQ P  +     N  ++ I      PE+ +F ++LIKCVVQLELIQTIDNIVFFP TSKKEDA+N+AAAQ             + + +      D GM+  L+S+QL     CL E+H FA+ FN N EQR  L KAGF KGKS PNLLKQET+SLA  LRILFR+Y +ESR  AWE V+++L  V +EA  YF  L S SHR+AWT++L+L LTK+LK+ D RF  H + +Y  LC+++  +L  ELR V+R+ FLR G V  +S
Sbjct:    6 KTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKAETEKQSPPHGEAKAGSSTLPPVKSKTNFIEAD--KYFLPFELACQ-SKCPRIVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFARMENQALQEAKQMEKERHRQHHHLLQSPVSHHEPESPQLRYLPPQTVDHISQEHEGDLDLHTNDVDKSLQDDTEPENGSDISSAENEQTEADQATAAET----LSKNEVLYDGENH----DCEEKP-------QDIVQNIVEEMVNIVVGDMGE--GTTINASADGN--------------IGT--------------IEDGS----DSENIQANGIPGTPISVAYTPSLP-------------DDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPIFRTNEMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQE-----KPSEQEMSEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKK-PKRGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQVGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRMFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSSKQNVA-----SEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTEVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSLTGTKDQAPDEFVGLGLVG---------GNVDWKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLSTTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTTGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYTSDDMNVAPEDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFRIVFRIFDNMKLPE---QQTEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPNSGETAPPPPSPVS------------------EKPLDTISQKSV------DIHDSIQPR---SVDNRPQAPL-VSASAVNEEVSKIKSTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQR-----------DAVDFDVRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGF-KGKSKPNLLKQETSSLACGLRILFRMYMDESRVSAWEEVQQRLLNVCSEALSYFLTLTSESHREAWTNLLLLFLTKVLKISDNRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGVVFQIS 1837          
The following BLAST results are available for this feature:
BLAST of TCONS_00051193-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
BIG10.000e+056.02Brefeldin A-inhibited guanine nucleotide-exchange ... [more]
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