TCONS_00051508-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00051508-protein
Unique NameTCONS_00051508-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1080

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00051508-protein ID=TCONS_00051508-protein|Name=TCONS_00051508-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1080bp
MRFKEKSETTWFTSVSSQSGGNQGGTMEKARKRQKIARCMVRFNALNESR
PRTDVGQPVLSEKRRCVTLYHPREPPELHRTASDPDLYRRSQENLAGPDP
SDNGDHSGTEDEKFTEYTAVGSHEDIHALAKQISVQEILTNFEDKNHHGI
RKPIPKPRKSIPSIFQELNTNKNGDTTTVANEQKSDDSDNGKTESHKSKR
PKPPPRPPSEDKPNIRPDEKPTIATKPKVLPKPSSKPPSPPVPDTPSLDQ
NCVKEDQASDKREPATDKKEPATDTRESATTINIEYKVSGGVTPNNKDSK
KDKTKLKQKSTKPKSFDSMPEAVPYEVVNICTPQPTSDDLYTEIPTGSKV
YEDPEEEYLSPVDGNSSSPEPPETPPATSTNHYATPSNSGTTSKSSTLRQ
LKEKRQRFNKSKYSKSMVGGSDKKKPAYDPNRRRTLPDLPASLADEMGAR
DRRLSEQQEIPIYGNSDVVSPSPSDDECWNSDEFESTDDEDDADFSINDG
DETQESGVTEEPIPKLPHLEGVKKKLYNIVTEILTTERAYVKRLFLLNQI
FNKRFIEASKEDSNIITDKAVADIFPFLQPIYEFHTKTLLPAIEERIKDW
EEKEQIGDIFLRLGAFLLLYQEYVKKFDNATSTLSHWLKKSPKFNTIVEE
LQKDPRSEHLSLQHHMLEPIQRVPRYKLLLADYLKRLPEDSNDQKDTRAA
LTIISKAAESSNNSMKENKKFTRLLEIEDRIVEGLREGLVLASREFLKEG
ELAKLAARSGNKNKRILILFNDMLLCCIQTPTGKLRVRQRLDLHHLCIMN
EEPDLPENSFSIKGKQKVLDFQASDEDEMNEWMSSIRNAVHEFERKRGTY
IEARMGEEEGSIVIGQQAPKWVKDDNVSMCMLCAFKFGLINRKHHCRGCG
RVVCGKCSAYKAHLSYADALLRVCYSCAVKMGVASEKDKVNEKLNNNVGK
RDSGSTSDMHGEMYWKAPNKEYKKQWIFLSNFALYIQKKRQDPKALQTLP
VPGYTVDLHNQAEDSENPYPHYIKIHKNNKKEFSYYIASDNKESIKLWYN
HLKCAINLETYKGQQNEDPKEEIEQPTPST
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_032643XLOC_032643Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00051508TCONS_00051508Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000219DH-domain
IPR000306Znf_FYVE
IPR001849PH_domain
IPR011993PH_dom-like
IPR013083Znf_RING/FYVE/PHD
IPR017455Znf_FYVE-rel
IPR011011Znf_FYVE_PHD
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO:0046872metal ion binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0046872 metal ion binding
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 529..713
e-value: 6.1E-48
score: 175.2
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 529..712
e-value: 2.0E-41
score: 142.1
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 525..714
score: 33.281
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 516..731
IPR000306FYVE zinc fingerSMARTSM00064fyve_4coord: 866..933
e-value: 4.1E-23
score: 92.8
IPR000306FYVE zinc fingerPFAMPF01363FYVEcoord: 870..929
e-value: 6.7E-17
score: 61.3
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 957..1059
e-value: 1.3E-8
score: 44.6
coord: 746..843
e-value: 2.8E-14
score: 63.4
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 747..840
e-value: 1.9E-7
score: 31.4
coord: 959..1055
e-value: 1.5E-7
score: 31.8
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 745..841
score: 11.349
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 956..1057
score: 10.782
IPR011993PH domain-likeGENE3D2.30.29.30coord: 723..849
e-value: 2.3E-24
score: 85.1
IPR011993PH domain-likeGENE3D2.30.29.30coord: 955..1078
e-value: 4.4E-12
score: 45.3
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 723..848
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 892..1056
NoneNo IPR availableGENE3D1.20.900.10coord: 522..722
e-value: 2.7E-51
score: 173.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..116
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 143..513
NoneNo IPR availableCDDcd00160RhoGEFcoord: 526..712
e-value: 7.21445E-42
score: 151.682
IPR013083Zinc finger, RING/FYVE/PHD-typeGENE3D3.30.40.10coord: 860..938
e-value: 5.9E-20
score: 70.4
IPR017455Zinc finger, FYVE-relatedPROSITEPS50178ZF_FYVEcoord: 874..932
score: 12.486
IPR011011Zinc finger, FYVE/PHD-typeSUPERFAMILY57903FYVE/PHD zinc fingercoord: 869..931

Blast
[Close]
BLAST of TCONS_00051508-protein vs. Swiss-Prot (Human)
Match: FGD4 (FYVE, RhoGEF and PH domain-containing protein 4 OS=Homo sapiens GN=FGD4 PE=1 SV=2)

HSP 1 Score: 349.747 bits (896), Expect = 3.351e-106
Identity = 200/569 (35.15%), Postives = 319/569 (56.06%), Query Frame = 0 
Query:  523 KKKLYNIVTEILTTERAYVKRLFLLNQIFNKRFIEASKEDSNIITDKAVADIFPFLQPIYEFHTKTLLPAIEERIKDWEEKEQIGDIFLRLGAFLLLYQEYVKKFDNATSTLSHWLKKSPKFNTIVEELQKDPRSEHLSLQHHMLEPIQRVPRYKLLLADYLKRLPEDSNDQKDTRAALTIISKAAESSNNSMKENKKFTRLLEIEDRIVEGLREGLVLASREFLKEGELAKLAARSGNKNKRILILFNDMLLCCI---QTPTGKLRVRQRLDLHHLCIMNEEPDLPENSFSIKGKQKVLDFQASDEDEMNEWMSSIRNAVHEFERKRGTYIEA-----RMGEEEGSIVIGQQAPKWVKDDNVSMCMLCAFKF-GLINRKHHCRGCGRVVCGKCSAYKAHLSY-ADALLRVCYSCAVKMGVASEKDKVNEKLNNNVGKRDSGSTSDMHGEMYWKAPNKEYKKQWIFLSN---FALYIQKKRQDPKALQTLPVPGYTVDLHNQAEDSENPYPHYIKIHKNNKKEFSYYIASDNKESIKLWYNHLKCAINLETYKGQQNEDPKEEIEQPTP 1078
            ++KL+ I  E+L TERAYV RL LL+Q+F  + +E +   S     + V  IF  +  I  FH+K LLP +E+R+++WE   +IGDI  +L  FL +Y EYVK FDNA   + +  ++ P+F ++VEE+QK      L+LQHHMLEP+QR+PRY++LL DYL++LP DS D  D + +L IIS AA  SN+++++ +   +LLEI + +  G  E +V  S E +KEG++ KLAAR+ +  +R L LFN+MLL C+        K  VR R+ +  + I+  + +   ++F + GK++ L+ QAS   +  EW+ +++  +  F ++  T+  A      +  E  +  +G++AP+W++D+ V+MCM C   F  L  R+HHCR CG VVC KCS YKA L Y    L +VC  C   +   ++ ++   K    +   +    S +   + +   +K ++K W  +       LY+    QD +A  T+P+ GY VD   ++ D     PH  K+ ++      +  A+D++E  + W   +  A+  ET  G  NE P    + P P
Sbjct:  204 EQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEANRGS--FPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEML--GEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIAKDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEKSKPWQKAWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDEMPRSAD----LPHSFKLTQSKS---VHSFAADSEELKQKWLKVILLAVTGET-PGGPNEHPATLDDHPEP 760
The following BLAST results are available for this feature:
BLAST of TCONS_00051508-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FGD43.351e-10635.15FYVE, RhoGEF and PH domain-containing protein 4 OS... [more]
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