TCONS_00052078-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00052078-protein
Unique Name	TCONS_00052078-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	472

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00052078-protein ID=TCONS_00052078-protein|Name=TCONS_00052078-protein|organism=Clytia hemisphaerica|type=polypeptide|length=472bp
RWKDIMMTYKSLMICLALSLIVNINIVTAGGKRRGSKDVMVEREIVDTIL
DGYNLDIRPEIKHGEPLHVHFEMKLQKIVRLDVKHQLFTINSFVRMKWID
TQLSWNKTEFENIDKTNVGTDMIWTPDVVLYNSATEESFAHTDLYKTKAL
VFHDGLVLWTAPVTWQVSCSFDVTWFPIDRQICTLTFGSWSYMSSQLKLS
FYENISPGEINHEQFSVKSGEWEIEDIEMSSGTVKYSCCPDPFSVIKYRF
SLRRMALYYFLYIILPLVSQVFLFLMVFHIPCENGERMGFGVTILLSITV
YLLVISEKLPEKSDDRPMLGICFIIEFYILSFALVVAAIIVKLSNRTSTP
PHFLLRFCGTSKSICCGAGHQTTTKNHANKKESIEMHEANGYLHSKDEGT
RFLHQRKTQPVAEQQPPVVAQPLEMDEEEINRKLWRKICNSLDRMCFYGF
GFISIFAPVLVVALLDHRMMGV

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_032984	XLOC_032984	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00052078	TCONS_00052078	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 122..133 score: 50.72 coord: 89..105 score: 34.15 coord: 250..262 score: 34.15 coord: 169..183 score: 47.78
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 263..416 e-value: 1.2E-17 score: 64.7
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 257..462
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 38..259 e-value: 2.0E-64 score: 216.5
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 43..254 e-value: 3.1E-57 score: 193.4
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 42..254
None	No IPR available	GENE3D	1.20.58.390		coord: 260..469 e-value: 3.1E-25 score: 88.1
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 169..183

Blast

[Close]

BLAST of TCONS_00052078-protein vs. Swiss-Prot (Human)
Match: ACHA6 (Neuronal acetylcholine receptor subunit alpha-6 OS=Homo sapiens GN=CHRNA6 PE=1 SV=1)

HSP 1 Score: 202.216 bits (513), Expect = 2.843e-59
Identity = 103/316 (32.59%), Postives = 181/316 (57.28%), Query Frame = 0

Query:   34 RGSKDVMVEREIVDTILDGYNLDIRPEIKHGEPLHVHFEMKLQKIVRLDVKHQLFTINSFVRMKWIDTQLSWNKTEFENIDKTNVGTDMIWTPDVVLYNSATEESFAHTDLYKTKALVFHDGLVLWTAPVTWQVSCSFDVTWFPIDRQICTLTFGSWSYMSSQLKLSFYENISPGEINHEQFSVKSGEWEIEDIEMSSGTVKYSCCPDPFSVIKYRFSLRRMALYYFLYIILPLVSQVFLFLMVFHIPCENGERMGFGVTILLSITVYLLVISEKLPEKSDDRPMLGICFIIEFYILSFALVVAAIIVKLSNRTST 349
            +G      E  +   +   YN  IRP     +P+ VHFE+ + ++  +D  +Q+   N ++R  W D +L W+  E++ I+   V  D IW PD+VLYN+A  +        KTKAL+ ++G++ WT P  ++ SC  D+T+FP D Q C+L FGSW+Y  +++ L     I   +++   F  ++ EWEI D       +KY+CC + ++ I Y F +RR+ ++Y + +I+P +   FL ++VF++P + GE++   +++LLS+TV+LLVI+E +P  S   P++G   +     ++ ++VV   ++ +  RT T
Sbjct:   26 KGCVGCATEERLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEG---KTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLL----IIGSKVDMNDFW-ENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPT 333

The following BLAST results are available for this feature:

BLAST of TCONS_00052078-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00052078-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA6	2.843e-59	32.59	Neuronal acetylcholine receptor subunit alpha-6 OS...	[more]

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TCONS_00052078-protein (polypeptide) - C. hemisphaerica