TCONS_00052979-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00052979-protein
Unique NameTCONS_00052979-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1293

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00052979-protein ID=TCONS_00052979-protein|Name=TCONS_00052979-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1293bp
MAWLGNIFGGGGTAATGGTEFVGQYVDIGQQKLRIKKVIAEGGYGFVFIA
QDSSSGKDYALKRLMSSDESSNKEIVREISFLRKLRGHPNIIQYIAAAAG
GEKQSTGLKEYLILTELCTGQLIQYLNSKPQISLNVCLQIFGQTCKAVAH
MHKQNPPIIHRDLKIENLLISDKGVIKLCDFGSATTDALYPDDSWSALQR
SMAEDEIQRNTTPMYRAPEMVDLYSNSSITVKADVWALGCVLYVLCFTRH
PFEDSAKLKIMNANYTIPEFDRTFQSIHHLIKSMLQVNPDKRPSVEDIHA
EIVALAADRQIDLKSPIMEQVSPTQVTTPEQEGTPVGSSFNVNSSQILGN
VVNKAGSLFSNIKDVSTKMMSSVAGYVNKDLDISYITPRLVVMSFPADGI
EGTYKNNIDDVRMYLDTKHPESYVVINISQRTYRTAKLNDRVYELGWNPK
RAPPLDKLVSLCRKLNNFLKQSKKNVVVVHCLDGRMASALMVSSFLLFTK
LFTKVSMAEDLFNNKRFHLQQYQQQQQQNQQNSTTSPTPPQTVELLPSQR
RYAGYVGRLVGTPRYLPHKNVVFLKSFTMSTVPIFNKARTGCRPFIEIYE
GDKRILSTAQEVEQMREYTQHDGKILFNTHIKICGDITIQVHHGRSTLGG
KVQGKLTSINILTVQFHTGFLDKETPTIKFAMSQLDIQESADKYPPSFGV
VMNLKVTNETPDNTYTEPWEKMNVEKLSPYGCFYSREEYWKLYEEYGLSE
EKTPLSTKRSTSSVSDSDNVDLPAGFKSGPPLRPKAPSPASSQAKANGSV
SIEPITTHTQDIPSKNDVANDQGGFSSLIDIGTPSPAHNAKEPFSDFQQQ
DVFNNQNIKPSNNKVDQEQLIDPFASLATSRTEGDGSSNNDVLLNFGSSQ
PTTPSTTQQPLFQTGPDILNTNSEMTQSNTPDLLQSGHFMGGLSSPTATS
GASTASNSLNDINSDDFFSRLGEPAASPQVAPSSKFGAAGSPFMGSHSPS
KQSGPRKSNSESNLLEMGDSFSQGDTLQPEMQPAMHHASSSGAVNNPQQT
SYDPFGDFGNFGSSSAQSNSASNLFSGGGMASARSSSARSSPTFNKNPTS
TTRPQQQQQRPTATQQSRQSTAPNYNVFVSNKQDSVFGKGTATPTGSGTW
GSKPMKNNDFSDILNAQGFTSANKQSATGQTLKQMKNEAETVEMDPVKRA
VREWSDGKERNIRALISSLQSILWEEAKQKWKPIGLHDIMQGNKVKTYYR
KACLAVHPDKHMGTENEQLARAIFLELNEAMTLFEEKGSQNMF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033454XLOC_033454Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00052979TCONS_00052979Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR014020Tensin_C2-dom
IPR001623DnaJ_domain
IPR029021Prot-tyrosine_phosphatase-like
IPR008271Ser/Thr_kinase_AS
IPR029023Tensin_phosphatase
IPR011009Kinase-like_dom
IPR000008C2_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 33..311
e-value: 8.1E-59
score: 211.4
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 35..299
e-value: 1.2E-49
score: 169.0
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 33..302
score: 40.23
IPR014020Tensin phosphatase, C2 domainSMARTSM01326PTEN_C2_2coord: 567..706
e-value: 4.2E-34
score: 129.3
IPR014020Tensin phosphatase, C2 domainPFAMPF10409PTEN_C2coord: 568..702
e-value: 5.8E-21
score: 74.6
IPR014020Tensin phosphatase, C2 domainPROSITEPS51182C2_TENSINcoord: 569..707
score: 18.259
NoneNo IPR availableGENE3D1.10.510.10coord: 135..333
e-value: 5.7E-44
score: 149.3
NoneNo IPR availableGENE3D2.60.40.1110coord: 566..710
e-value: 8.6E-25
score: 86.5
NoneNo IPR availableGENE3D3.30.200.20coord: 21..134
e-value: 1.2E-22
score: 79.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 751..798
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 897..957
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 970..1159
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 522..544
IPR001623DnaJ domainGENE3D1.10.287.110coord: 1160..1288
e-value: 2.7E-16
score: 59.4
IPR001623DnaJ domainPROSITEPS50076DNAJ_2coord: 1229..1293
score: 9.236
IPR001623DnaJ domainSUPERFAMILY46565Chaperone J-domaincoord: 1153..1287
IPR029021Protein-tyrosine phosphatase-likeGENE3D3.90.190.10coord: 360..540
e-value: 1.6E-22
score: 79.4
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILY52799(Phosphotyrosine protein) phosphatases IIcoord: 380..528
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 158..170
IPR029023Tensin-type phosphatase domainPROSITEPS51181PPASE_TENSINcoord: 372..563
score: 15.992
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 26..300
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 570..704

Blast
BLAST of TCONS_00052979-protein vs. Swiss-Prot (Human)
Match: GAK (Cyclin-G-associated kinase OS=Homo sapiens GN=GAK PE=1 SV=2)

HSP 1 Score: 712.22 bits (1837), Expect = 0.000e+0
Identity = 346/770 (44.94%), Postives = 501/770 (65.06%), Query Frame = 0
Query:   11 GGTAATGGTEFVGQYVDIGQQKLRIKKVIAEGGYGFVFIAQDSSSGKDYALKRLMSSDESSNKEIVREISFLRKLRGHPNIIQYIAAAAGGEKQS-TGLKEYLILTELCTGQLIQYL---NSKPQISLNVCLQIFGQTCKAVAHMHKQNPPIIHRDLKIENLLISDKGVIKLCDFGSATTDALYPDDSWSALQRSMAEDEIQRNTTPMYRAPEMVDLYSNSSITVKADVWALGCVLYVLCFTRHPFEDSAKLKIMNANYTIPEFDRTFQSIHHLIKSMLQVNPDKRPSVEDIHAEIVALAADRQIDLKSPIMEQVSPTQVTTPEQEGTPVGSSFN--------------------VNSSQILGNVVN--KAGS--LFSNIKDVSTKMMSSVAGYVNKDLDISYITPRLVVMSFPADGIEGTYKNNIDDVRMYLDTKHPESYVVINISQRTYRTAKLNDRVYELGWNPKRAPPLDKLVSLCRKLNNFLKQSKKNVVVVHCLDGRMASALMVSSFLLFTKLFTKVSMAEDLFNNKRFHLQQYQQQQQQNQQNSTTSPTPPQTVELLPSQRRYAGYVGRLVGTPRYLPHKNVVFLKSFTMSTVPIFNKARTGCRPFIEIYEGDKRILSTAQEVEQMREYTQHDGKILFNTHIKICGDITIQVHHGRSTLGGKVQGKLTSINILTVQFHTGFLDKETPTIKFAMSQLDIQESADKYPPSFGVVMNLKVTNETPDNTYTE--PWEKMNVEKLSPYGCFYSREEYWKLYEEYGLSE 750
            GG +    ++FVGQ V++G+ +LR+++V+AEGG+ FV+ AQD  SG++YALKRL+S++E  N+ I++E+ F++KL GHPNI+Q+ +AA+ G+++S TG  E+L+LTELC GQL+++L    S+  +S +  L+IF QTC+AV HMH+Q PPIIHRDLK+ENLL+S++G IKLCDFGSATT + YPD SWSA +R++ E+EI RNTTPMYR PE++DLYSN  I  K D+WALGC+LY+LCF +HPFED AKL+I+N  Y+IP  D  +   H LI++MLQVNP++R S+ ++  ++  +AA R ++ KSPI E +        EQ G    ++ +                        Q  G  ++  + G+  LF+N+KD S+K++ SVA Y   DLDISYIT R+ VMSFPA+G+E   KNNI+DVR++LD+KHP  Y V N+S RTYR ++ ++RV E GW  +RAP L  L ++CR ++ +L+Q  KNV VVHC+DGR ASA+ V SFL F +LF+    A  +F+ KR                      PP    + PS +RY  Y+  +V      PH   + +++  M+ VP+F+K R+GCRPF E+Y GD+R+ ST+QE ++MR++   DGK +    + + GD+ I ++H RSTLGG++Q K+ S+ +  +QFHTGF+ +   T+KFA   LD  +  +KYP  F V  NL+V  E  D    E  PWE  ++  L+P   F SREE   +  ++G  E
Sbjct:   18 GGASGRDQSDFVGQTVELGELRLRVRRVLAEGGFAFVYEAQDVGSGREYALKRLLSNEEEKNRAIIQEVCFMKKLSGHPNIVQFCSAASIGKEESDTGQAEFLLLTELCKGQLVEFLKKMESRGPLSCDTVLKIFYQTCRAVQHMHRQKPPIIHRDLKVENLLLSNQGTIKLCDFGSATTISHYPDYSWSAQRRALVEEEITRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFRQHPFEDGAKLRIVNGKYSIPPHDTQYTVFHSLIRAMLQVNPEERLSIAEVVHQLQEIAAARNVNPKSPITELL--------EQNGGYGSATLSRGPPPPVGPAGSGYSGGLALAEYDQPYGGFLDILRGGTERLFTNLKDTSSKVIQSVANYAKGDLDISYITSRIAVMSFPAEGVESALKNNIEDVRLFLDSKHPGHYAVYNLSPRTYRPSRFHNRVSECGWAARRAPHLHTLYNICRNMHAWLRQDHKNVCVVHCMDGRAASAVAVCSFLCFCRLFSTAEAAVYMFSMKR---------------------CPPG---IWPSHKRYIEYMCDMVAEEPITPHSKPILVRAVVMTPVPLFSKQRSGCRPFCEVYVGDERVASTSQEYDKMRDFKIEDGKAVIPLGVTVQGDVLIVIYHARSTLGGRLQAKMASMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLFQV--NLEVEVEPRDRPSREAPPWENSSMRGLNPKILFSSREEQQDILSKFGKPE 753          
The following BLAST results are available for this feature:
BLAST of TCONS_00052979-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GAK0.000e+044.94Cyclin-G-associated kinase OS=Homo sapiens GN=GAK ... [more]
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