TCONS_00054268-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00054268-protein
Unique NameTCONS_00054268-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length494

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00054268-protein ID=TCONS_00054268-protein|Name=TCONS_00054268-protein|organism=Clytia hemisphaerica|type=polypeptide|length=494bp
MLFFLETIFIFSALLYVQDSEAVLSCGDPGPIYNGTIIGKANFNNGGIIR
YKCNKCYDRKGPSTLMCSRWGHWSGDVPKCLPKECPPLVVSDNEKTLTGK
RYGFEYQFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQP
PIHEGYCPPPEPLHNGIIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTY
RECGWHGKWDHDNPYCQKKKDEDTEPDNVASVFNLVEYCSRLFPPIDGEV
MGSNQVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKCKPACSVHEC
PSNKKCVLDAITQRPTCECNLKNKCPNYRSAVCADDGRTYRNECRMKLAA
CTMNKDLKILHDGPCEPIPSCHIQPNKQCTKQLKKPVYRYNEEKGICEQT
TQSTCHKTGFNGYWKKQDCEYYCGKTGVCTLDKDKGPCRNARPMMRWHYV
PKFKTCRRFIYFGCYGNANNFATGHECFTFCTDNQVKKKRKSLA
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_034232XLOC_034232Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00054268TCONS_00054268Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002223Kunitz_BPTI
IPR002350Kazal_dom
IPR000436Sushi_SCR_CCP_dom
IPR020901Prtase_inh_Kunz-CS
Vocabulary: Molecular Function
TermDefinition
GO:0004867serine-type endopeptidase inhibitor activity
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005515 protein binding
molecular_function GO:0004867 serine-type endopeptidase inhibitor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002223Pancreatic trypsin inhibitor Kunitz domainPRINTSPR00759BASICPTASEcoord: 456..466
score: 55.64
coord: 466..481
score: 47.16
coord: 426..440
score: 34.85
IPR002223Pancreatic trypsin inhibitor Kunitz domainSMARTSM00131KU_2coord: 427..482
e-value: 1.8E-14
score: 64.1
IPR002223Pancreatic trypsin inhibitor Kunitz domainPFAMPF00014Kunitz_BPTIcoord: 428..481
e-value: 3.4E-14
score: 52.7
IPR002223Pancreatic trypsin inhibitor Kunitz domainGENE3D4.10.410.10coord: 370..494
e-value: 4.8E-21
score: 74.6
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 429..481
score: 14.023
IPR002223Pancreatic trypsin inhibitor Kunitz domainSUPERFAMILY57362BPTI-likecoord: 427..483
IPR002350Kazal domainSMARTSM00280kazal_3coord: 318..365
e-value: 2.5E-13
score: 60.3
IPR002350Kazal domainPFAMPF07648Kazal_2coord: 322..365
e-value: 2.4E-11
score: 43.5
IPR002350Kazal domainPROSITEPS51465KAZAL_2coord: 318..367
score: 11.556
IPR002350Kazal domainSUPERFAMILY100895Kazal-type serine protease inhibitorscoord: 316..366
IPR000436Sushi/SCR/CCP domainSMARTSM00032CCP_2coord: 85..137
e-value: 0.0011
score: 28.2
coord: 157..216
e-value: 2.0E-10
score: 50.7
coord: 26..80
e-value: 1.6E-9
score: 47.6
coord: 239..291
e-value: 2.6E-9
score: 46.9
IPR000436Sushi/SCR/CCP domainPFAMPF00084Sushicoord: 26..80
e-value: 9.1E-7
score: 29.3
coord: 157..216
e-value: 4.9E-8
score: 33.4
coord: 98..137
e-value: 0.0013
score: 19.2
coord: 252..291
e-value: 6.9E-8
score: 32.9
IPR000436Sushi/SCR/CCP domainPROSITEPS50923SUSHIcoord: 24..82
score: 10.136
IPR000436Sushi/SCR/CCP domainPROSITEPS50923SUSHIcoord: 155..218
score: 10.157
IPR000436Sushi/SCR/CCP domainPROSITEPS50923SUSHIcoord: 83..139
score: 9.38
IPR000436Sushi/SCR/CCP domainPROSITEPS50923SUSHIcoord: 237..293
score: 10.167
IPR000436Sushi/SCR/CCP domainCDDcd00033CCPcoord: 26..80
e-value: 1.26734E-7
score: 47.8428
IPR000436Sushi/SCR/CCP domainCDDcd00033CCPcoord: 85..138
e-value: 5.77448E-6
score: 42.8352
IPR000436Sushi/SCR/CCP domainCDDcd00033CCPcoord: 239..292
e-value: 3.07197E-7
score: 46.6872
IPR000436Sushi/SCR/CCP domainCDDcd00033CCPcoord: 157..217
e-value: 3.39672E-9
score: 52.4652
IPR000436Sushi/SCR/CCP domainSUPERFAMILY57535Complement control module/SCR domaincoord: 25..90
IPR000436Sushi/SCR/CCP domainSUPERFAMILY57535Complement control module/SCR domaincoord: 77..138
IPR000436Sushi/SCR/CCP domainSUPERFAMILY57535Complement control module/SCR domaincoord: 156..218
IPR000436Sushi/SCR/CCP domainSUPERFAMILY57535Complement control module/SCR domaincoord: 237..295
NoneNo IPR availableGENE3D2.10.70.10coord: 153..219
e-value: 1.8E-12
score: 47.2
NoneNo IPR availableGENE3D2.10.70.10coord: 25..81
e-value: 1.3E-13
score: 50.9
NoneNo IPR availableGENE3D3.30.60.30coord: 302..366
e-value: 7.7E-16
score: 58.0
NoneNo IPR availableGENE3D2.10.70.10coord: 246..301
e-value: 4.2E-11
score: 42.4
NoneNo IPR availableGENE3D2.10.70.10coord: 82..139
e-value: 7.3E-10
score: 38.8
NoneNo IPR availableCDDcd00104KAZAL_FScoord: 325..365
e-value: 3.36677E-9
score: 51.887
NoneNo IPR availableCDDcd00109KUcoord: 428..481
e-value: 7.47532E-13
score: 62.6526
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 459..477

Blast
BLAST of TCONS_00054268-protein vs. Swiss-Prot (Human)
Match: SVEP1 (Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 OS=Homo sapiens GN=SVEP1 PE=1 SV=3)

HSP 1 Score: 108.612 bits (270), Expect = 9.937e-25
Identity = 79/272 (29.04%), Postives = 119/272 (43.75%), Query Frame = 0
Query:   24 LSCGDPGPIYNGTIIGKANFNNGGIIRYKCNKCYDRKGPSTLMCSRWGHWSGDVPKCLPKEC--PPLVVSDNEKTLTGKRYGFEYQFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQPPIHEGYCPPPEPLHNGIIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTYRECGWHGKWD-HDNPYCQKKKDEDTEPDNVASVFNLVEYCSRLFPPIDGEVMGSNQVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKCK 292
            + CG+P  I NG   G +N++ G ++ Y CNK +  KG     C   G WS  +P C P  C  PP V +   +  TG+ +  E ++ C  G   +G  +  C  N  W S+ P+  VP+               C  P P+ NG ++       E ++VG +V F CN  Y L+G +   C   GKW+   NP C   K    EP  + +   L E               + +VG  + F C +G+ + G +   CL + QW+   P CK
Sbjct: 2144 VRCGEPPSIMNGYASG-SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLD--------------CGKPPPIQNGFMKG------ENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAK--CPEPPLLENQLVLKEL--------------TTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2377          

HSP 2 Score: 100.908 bits (250), Expect = 2.803e-22
Identity = 72/259 (27.80%), Postives = 104/259 (40.15%), Query Frame = 0
Query:   40 KANFNNGGIIRYKCNKCYDRKGPSTLMCSRWGHWSGDVPKCLPKECP-PLVVSDNEKTLTGKRYGFEYQFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQPPIHEGYCPPPEPLHNGIIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTYRECGWHGKWDHDNPYCQKKKDEDTEPDNVASVFNLVEYCSRLFPPI--DGEVMGSN-QVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKCKPA 294
             +NF  G ++ Y CN  Y+  G   L+C   G W+G  P C+  EC  P    +     T    G   Q++C+ G +L G  +  C+ N +WS   P C                   C  P P+ NG I+         Y     +Y+ C+  Y L G   R C     WD D P C         P + +S            PP+  +G+V G        +E+ C++G+ + GA   +CL NG WS  TP C P 
Sbjct: 2672 SSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAIS---------------CKKPNPVMNGSIKG------SNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICI--------PVDCSS------------PPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPV 2889          

HSP 3 Score: 98.2117 bits (243), Expect = 1.990e-21
Identity = 78/273 (28.57%), Postives = 113/273 (41.39%), Query Frame = 0
Query:   23 VLSCGDPGPIYNGTIIGKANFNNGGIIRYKCNKCYDRKGPSTLMCSRWGHWSGDVPKCLPKECPPLVVSDNEKTLTGKRYGF--EYQFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQPPIHEGYCPPPEPLHNGIIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTYRECGWHGKWDHDNPYCQKKKDEDTEPDNVASVFNLVEYCSRLFPPIDGEVMGSNQVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKCKP 293
             +SC  P P+ NG+I G +N+     + Y+C+  Y   G     C    +W  D P C+P +C    VS N + + G  Y F  E ++TC  G +L G     C+ NG WS   P C VP+               C  P  L NG+ + + +G  ++      V F C+  Y L G     C   G WD + P C+        P N     +L       F  I G           ++++C  GY + G +   CL NG WS  +P C P
Sbjct: 2772 AISCKKPNPVMNGSIKG-SNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ-VRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC-VPVR--------------CATPPQLANGVTEGLDYGFMKE------VTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCK--------PVNCGPPEDLAHGFPNGFSFIHG---------GHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLP 3004          

HSP 4 Score: 93.9745 bits (232), Expect = 5.079e-20
Identity = 79/275 (28.73%), Postives = 116/275 (42.18%), Query Frame = 0
Query:   24 LSCGDPGPIYNGTIIGKANFNNGGIIRYKCNKCYDRKGPSTLMCSRWGHWSGDV-PKCLPKECPPLVVSDNEKTLTGKRYGFEY---QFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQPPIHEGYCPPPEPLHNGIIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTYRECGWHGKWDHDNPYCQKKKDEDTE--PDNVASVFNLVEYCSRLFPPIDGEVMGSNQVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKCK 292
            L CG P PI NG + G+ NF  G  +++ CN+ Y+  G S+  C + G W+    PKC+P +CP   + +N+  L  K    E     F+C+ G VL G ++ +C+ + +W+   PVC++ + T PP     I  G   P   LH        FG+  KY         C   + L G +   C   G W    P C   +    E  P+ +  V  L    + L                   + C  G+ +VG   TLC  NG W    P CK
Sbjct: 2262 LDCGKPPPIQNGFMKGE-NFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVL--KELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPL----ISFGVPIPSSALH--------FGSTVKYS--------CVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTAL-------------------YTCKPGFELVGNTTTLCGENGHWLGGKPTCK 2494          

HSP 5 Score: 90.5077 bits (223), Expect = 6.767e-19
Identity = 71/273 (26.01%), Postives = 105/273 (38.46%), Query Frame = 0
Query:   23 VLSCGDPGPIYNGTIIGKANFNNGGIIRYKCNKCYDRKGPSTLMCSRWGHWSGDVPKCLPKECP-PLVVSDNEKTLTGKRYGFEYQFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQPPIHEGYCPPPEPLHNGIIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTYRECGWHGKWDHDNPYCQKKKDEDTEPDNVASVFNLVEYCSRLFPPIDGEVMGSN-QVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKCKP 293
            ++ C  P  I  G  I  +  + G  ++Y C   +  +G ST +C   G WS  +P+C+P ECP P  + +    + G  Y     +TC+ G  L+G   T C  NG W    P C+                  C  P+ + NG               G  V + CN  +RL GP+   C   G WD D P C                     +C    P  +G V G++   G+ + + C  G+ + G     C  +G WS   P C P
Sbjct: 2378 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIE---------------CLKPKEILNGKFSYTDL------HYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAI------------------HCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMP 2610          

HSP 6 Score: 90.1225 bits (222), Expect = 7.262e-19
Identity = 77/296 (26.01%), Postives = 114/296 (38.51%), Query Frame = 0
Query:   23 VLSCGDPGPIYNGTIIGKANFNNGGIIRYKCNKCYDRKGPSTLMCSRWGHWSGDVPKCLPKECP-PLVVSDNEKTLTGKRYGFEYQFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQPPIHEGYCPPPEPLHNGIIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTYRECGWHGKWDHDNPYCQKKK-DEDTEPDNVASVFNLVEYCSRLFPPIDGEVMGSNQVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKCKPACSVHEC---PSNKKCVLDAITQ 313
             +SCG P    NG I   A F  G  + Y+CNK Y   G     C     WS   P C P +C  P  +++ +  L+G  Y     ++C+ G  L G +I  C  +G W   PP C               H  +C  P  + + +I      T   +   + V + C   Y L G    EC   GKW   +  C     DE    D+ +      E   RLF             G    + C DGY++   ++ LC   G+W     +  P C  H C   PS    +L+++++
Sbjct: 1844 AVSCGKPAIPENGCIEELA-FTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC---------------HLVFCGEPPAIKDAVI------TGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASP-----ETAHRLF-------------GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSK 2099          

HSP 7 Score: 83.5741 bits (205), Expect = 9.378e-17
Identity = 67/275 (24.36%), Postives = 107/275 (38.91%), Query Frame = 0
Query:   24 LSCGDPGPIYNGTIIGKANFNNGGIIRYKCNKCYDRKGPSTLMCSRWGHWSGDVPKCLPKECPPLVVSDN----EKTLTGKRYGFEYQFTCEAGTVLIGRAITRCMCNGRWSSKPPVCRVPMATVPPTTQPPIHEGYCPPPEPLHNG--IIQAVRFGTEEKYQVGDRVYFLCNIRYRLIGPTYRECGWHGKWDHDNPYCQKKKDEDTEPDNVASVFNLVEYCSRLFPPIDGEVMGSN-QVGSFMEFRCHDGYTMVGANKTLCLRNGQWSKITPKC 291
            + C  PG   NG   G+  +  G  + + C + Y   G + + C   G W+  +P C    C    + +N    E   T   +G +  + C  G  L G   + C+ N  WS  PPVC             P+    C  PE ++NG  I+  + + +   Y         C+  Y L GP+  EC   G WD   P C                   + +C       D  + G+N    + + + C +GYT+ G +   CL +G+WS+   +C
Sbjct: 1787 IKCKAPGNPENGHSSGEI-YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT---FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCE------------PVK---CSSPENINNGKYILSGLTYLSTASYS--------CDTGYSLQGPSIIECTASGIWDRAPPACH------------------LVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2016          
The following BLAST results are available for this feature:
BLAST of TCONS_00054268-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
SVEP19.937e-2529.04Sushi, von Willebrand factor type A, EGF and pentr... [more]
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