TCONS_00054846-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00054846-protein
Unique NameTCONS_00054846-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1265

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00054846-protein ID=TCONS_00054846-protein|Name=TCONS_00054846-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1265bp
MDKMLRIVLFLVGCFGLGSCLPPNNASLEFVAKDWAPPWPYPFPRPPNLP
SRKMVFKGVRFTVNCTTNDPDAVVQLFERVKNENSKNSEIEKGGRIQKVN
QTFVIDPVESIDIRDYECIAEDARGQEKILKLGFLNVNRLSVLDPIELYP
RENPTFIHEDEKKAINCSSEGHPGFQEKDLILSWYRLVNGKEVKITDGVI
HRDYTDNNRGGTLDYADLVFTKFSKNDEGVYICKRILDKHVKAKNVTLKL
ITPYKPKVALPQLPSGKFSRPTGYRATVVCELISSPPPSVKKWMKGSTVI
EDCSPYTASDCILSIGATQHSKDSGDYYCVGENKMGETKVKLDLQITEKV
ELDKPTTTIAVIYEEDRELVCNVAKANPPPTIVWEYQVDTCEKADDNCVP
LDNEWKRVTEQTPESETPTMKSKIISKATQKNHFYRCVATNKVASIQLNQ
FETASDTYNFKVIRTERSKVQFVFLAESTAINENDKINISCIVDMTKYKK
PRISKIGDNRLLTVTQTSGANNIDTFTYWKPISELTDSGSYICEAENQRG
TNSNSQTLEINIEPLVKAEITDFEDMSVSQNDRKNLRIFCNATGNPAPVI
TWTKDGKLLDDLTVINGINQCRTLKKGIYIRKKKRSLVICNLNFKDHGGT
YECCAKNALADVKESLELLVYAKPVIRDLPAERTFGVGDGDSIFCTSVAN
PPANVTWERVTNNSTVQIGFTAVEKVPLDFAKVSKDDAGPYRCTATNEFG
TVSETVDVIVKGTTGGLLGSDQKSTIIGIVVAFALLLIIIIIFVCWYRRH
LKAKYAKYLEPNETFILDPDRTLFDQSNDLPYDMSWEFPRERVTFIKTLG
SGAFGQVWLAEAEGLHSFKPRENTPDARRRRKSIQKGRNRYHSMSFRYKK
QTQNFEMSLEKMMVAVKTLKDGAAESEYKDLASELKILIHLGEHKNIVNL
LGACTTGGKLCVILECCPHGSLLNFLRSKRDVFKPAWAKHEVDMEKECSY
IDLAMTAWQVSKGMDFLQTKKLIHRDLAARNVLVGDDYIMKIADFGLARD
IYADEFYLKNTTGLLPIKWMAPESIFDRVYTTSSDVWSYGILLWEIFTLG
GSPYPGLPTENLRDYLESGRRMECPEQCPKDIYEIMLDCWAKSPYERPLF
AQITERLNNCMKQNISTGDAPQNYLDFTDAQDNYLQPEKAANQPPPEYLQ
ASAGDDNLKDDADRPLLAKGGNDYLEDDFANHPPPPPPPDNDYPEDRYVS
SDQHYKVPKSNAERV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_034547XLOC_034547Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00054846TCONS_00054846Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR003598Ig_sub2
IPR020635Tyr_kinase_cat_dom
IPR003599Ig_sub
IPR013783Ig-like_fold
IPR013098Ig_I-set
IPR001824Tyr_kinase_rcpt_3_CS
IPR008266Tyr_kinase_AS
IPR007110Ig-like_dom
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
molecular_function GO:0004714 transmembrane receptor protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 1016..1034
score: 59.97
coord: 1065..1075
score: 65.7
coord: 1128..1150
score: 46.26
coord: 1084..1106
score: 68.59
coord: 964..977
score: 45.95
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 844..1157
e-value: 4.1E-90
score: 301.5
IPR003598Immunoglobulin subtype 2SMARTSM00408igc2_5coord: 581..660
e-value: 7.4E-5
score: 32.1
coord: 271..336
e-value: 0.036
score: 20.9
coord: 688..750
e-value: 0.026
score: 22.3
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 843..1157
e-value: 1.5E-129
score: 446.4
IPR003599Immunoglobulin subtypeSMARTSM00409IG_3ccoord: 265..347
e-value: 7.0
score: 12.8
coord: 680..761
e-value: 0.0033
score: 26.7
coord: 573..671
e-value: 0.0081
score: 25.4
coord: 50..140
e-value: 5.6
score: 13.6
coord: 152..251
e-value: 0.35
score: 19.9
coord: 476..563
e-value: 6.7
score: 13.0
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 41..135
e-value: 2.5E-4
score: 20.3
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 250..343
e-value: 1.9E-9
score: 37.2
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 344..465
e-value: 3.6E-5
score: 23.2
coord: 670..765
e-value: 6.7E-12
score: 44.8
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 593..669
e-value: 2.7E-9
score: 36.6
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 548..592
e-value: 1.2E-5
score: 25.0
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 466..547
e-value: 7.8E-7
score: 28.9
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 138..249
e-value: 2.0E-5
score: 24.0
NoneNo IPR availableGENE3D1.20.5.100coord: 769..805
e-value: 3.4E-5
score: 22.9
NoneNo IPR availableGENE3D3.30.200.20coord: 825..971
e-value: 5.6E-21
score: 74.1
NoneNo IPR availableGENE3D1.10.510.10coord: 972..1217
e-value: 2.0E-47
score: 161.0
NoneNo IPR availablePFAMPF13927Ig_3coord: 580..657
e-value: 6.0E-10
score: 39.5
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 905..1007
e-value: 2.7E-31
score: 106.5
coord: 317..451
e-value: 2.6E-6
score: 23.7
coord: 444..871
e-value: 8.0E-34
score: 114.8
coord: 44..322
e-value: 2.8E-7
score: 26.9
coord: 988..1225
e-value: 2.5E-76
score: 255.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 870..889
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1187..1265
NoneNo IPR availablePROSITEPS51257PROKAR_LIPOPROTEINcoord: 1..20
score: 6.0
NoneNo IPR availableCDDcd00096Igcoord: 276..341
e-value: 1.11791E-4
score: 40.9355
NoneNo IPR availableCDDcd00096Igcoord: 692..756
e-value: 3.21423E-6
score: 45.5579
NoneNo IPR availableCDDcd00096Igcoord: 586..667
e-value: 2.59521E-8
score: 51.7211
IPR013098Immunoglobulin I-setPFAMPF07679I-setcoord: 674..760
e-value: 2.8E-8
score: 33.6
IPR001824Tyrosine-protein kinase, receptor class III, conserved sitePROSITEPS00240RECEPTOR_TYR_KIN_IIIcoord: 942..955
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 1022..1034
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 256..347
score: 9.664
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 468..559
score: 6.851
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 355..449
score: 7.159
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 674..759
score: 10.281
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 564..669
score: 10.517
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 150..233
score: 7.976
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 670..761
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 280..346
coord: 226..233
coord: 147..193
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 357..448
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 582..674
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 471..560
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 843..1161
score: 39.58
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 821..867
coord: 908..1156

Blast
[Close]
BLAST of TCONS_00054846-protein vs. Swiss-Prot (Human)
Match: FGFR3 (Fibroblast growth factor receptor 3 OS=Homo sapiens GN=FGFR3 PE=1 SV=1)

HSP 1 Score: 346.28 bits (887), Expect = 2.920e-103
Identity = 222/658 (33.74%), Postives = 334/658 (50.76%), Query Frame = 0 
Query:  585 NLRIFCNATGNPAPVITWTKDGKLLDDLTVINGINQCRTLKKGIYIRKKKRSLVICNLNFKDHGGTYECCAKNALADVKESLELLVYAK----PVIR-DLPAERTFGVGDGDSIFCTSVANPPANVTWERVTNNSTVQIG-----FTAVEKVP-----------LDFAKVSKDDAGPYRCTATNEFGTVSETVDVIVKGTTGGLLGSDQKSTIIGIVVA-----FALLLIIIIIFVCWYRRHLKA--------KYAKY-------LEPNETF-----ILDPDR-------TLFDQSN-DLPYDMSWEFPRERVTFIKTLGSGAFGQVWLAEAEGLHSFKPRENTPDARRRRKSIQKGRNRYHSMSFRYKKQTQNFEMSLEKMMVAVKTLKDGAAESEYKDLASELKILIHLGEHKNIVNLLGACTTGGKLCVILECCPHGSLLNFLRSKRDVFKPAWAKHEVDM----EKECSYIDLAMTAWQVSKGMDFLQTKKLIHRDLAARNVLVGDDYIMKIADFGLARDIYADEFYLKNTTGLLPIKWMAPESIFDRVYTTSSDVWSYGILLWEIFTLGGSPYPGLPTENLRDYLESGRRMECPEQCPKDIYEIMLDCWAKSPYERPLFAQITERLNNCMKQNISTGDAPQNYLDFTDAQDNY 1184
             +R  C A GNP P I+W K+G+       I GI           +R ++ SLV+ ++   D G  Y C  +N    ++++  L V  +    P+++  LPA +T  +G      C   ++   ++ W +    +  ++G     +  V K             L    V+ +DAG Y C A N  G    +  ++V      L+ +D+  ++   +++     F  +L++  + +C  R   K         K +++       LE N +      ++   R       TL + S  +LP D  WE  R R+T  K LG G FGQV +AEA G+          D  R  K +                             VAVK LKD A + +  DL SE++++  +G+HKNI+NLLGACT GG L V++E    G+L  FLR++R    P    +  D     E++ ++ DL   A+QV++GM++L ++K IHRDLAARNVLV +D +MKIADFGLARD++  ++Y K T G LP+KWMAPE++FDRVYT  SDVWS+G+LLWEIFTLGGSPYPG+P E L   L+ G RM+ P  C  D+Y IM +CW  +P +RP F Q+ E L+  +   +++ D    YLD +   + Y
Sbjct:  171 TVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIK----------LRHQQWSLVMESVVPSDRG-NYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGI----------DKDRAAKPV----------------------------TVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARR----PPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVL--TVTSTD---EYLDLSAPFEQY 770
The following BLAST results are available for this feature:
BLAST of TCONS_00054846-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FGFR32.920e-10333.74Fibroblast growth factor receptor 3 OS=Homo sapien... [more]
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