Sequence
The following sequences are available for this feature:
polypeptide sequence
>TCONS_00056152-protein ID=TCONS_00056152-protein|Name=TCONS_00056152-protein|organism=Clytia hemisphaerica|type=polypeptide|length=486bp KMTYFKKLLQSLSKTIQRGDLGEYGQHYMIAPMTNEEVINVQTCFTLNGT QDAVVEPQQALPDTSKFIHKGMKNWDNRNVDVWELVDTHGIKINRYTLYV DSQTLHPVFYEMLGYNSLLGSHFDEYKLYYTIFAEDFPVDVFNIPTDMKC SGFPGPGHEARIVANPMKEFIYPEDHSHLHQMYSDFVKKFSKQNVGEEKK HTFKHNLRYINSMNRKRLTYRLAVNHFADNSPSELRRLRGRLSGSNNKKH IKSNAKKFVSAVNVKDLPTQINWRLRGGVTPVKDQAVCGSCWSFGTTGTI EGAVFMKTGHLIRLSQQNLMDCSWGFGNNGCDGGEEFRAYEWIIKHGGIA TELNYGQYLGVDSFCHFNQSQAGAVLSGYVNVTSGSEDALKEAIATKGPT SVGIDAAHLSFVFYANGVYYEPKCGNGPDDLDHAVLAAGYGTLDGEDYWL VKNSWSTHWGNDGYVLMSRKDNNCGVATAATYVELK Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following
gene feature:
This polypeptide derives from the following
transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term Definition
GO:0006508 proteolysis
Vocabulary: Molecular Function
Term Definition
GO:0008234 cysteine-type peptidase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category
Term Accession
Term Name
biological_process
GO:0006508
proteolysis
molecular_function
GO:0008234
cysteine-type peptidase activity
InterPro
Analysis Name:
InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
50 100 150 200 250 300 350 400 450 Score = 51.08 Score = 54.15 Score = 75.76 Expect = 1.8E-96 / Score = 336.5 Expect = 6.4E-70 / Score = 235.6 Expect = 5.0E-10 / Score = 49.3 Expect = 1.2E-7 / Score = 32.0 Expect = 2.5E-94 / Score = 315.8 Expect = 3.27156E-100 / Score = 301.465 Score = Score = Score = Score = Sequence PR00705 SM00645 PF00112 SM00848 PF08246 G3DSA:3.90.70.10 cd02248 SSF54001 PS00640 PS00139 PS00639
IPR Term IPR Description Source Source Term Source Description Alignment
IPR000668 Peptidase C1A, papain C-terminal PRINTS PR00705 PAPAIN coord: 448..454 score: 75.76 coord: 433..443 score: 54.15 coord: 285..300 score: 51.08
IPR000668 Peptidase C1A, papain C-terminal SMART SM00645 pept_c1 coord: 267..484 e-value: 1.8E-96 score: 336.5
IPR000668 Peptidase C1A, papain C-terminal PFAM PF00112 Peptidase_C1 coord: 267..482 e-value: 6.4E-70 score: 235.6
IPR013201 Cathepsin propeptide inhibitor domain (I29) SMART SM00848 Inhibitor_I29_2 coord: 183..235 e-value: 5.0E-10 score: 49.3
IPR013201 Cathepsin propeptide inhibitor domain (I29) PFAM PF08246 Inhibitor_I29 coord: 185..234 e-value: 1.2E-7 score: 32.0
None No IPR available GENE3D 3.90.70.10 coord: 179..486 e-value: 2.5E-94 score: 315.8
None No IPR available CDD cd02248 Peptidase_C1A coord: 268..483 e-value: 3.27156E-100 score: 301.465
None No IPR available SUPERFAMILY 54001 Cysteine proteinases coord: 178..483
IPR025661 Cysteine peptidase, asparagine active site PROSITE PS00640 THIOL_PROTEASE_ASN coord: 448..467
IPR000169 Cysteine peptidase, cysteine active site PROSITE PS00139 THIOL_PROTEASE_CYS coord: 285..296
IPR025660 Cysteine peptidase, histidine active site PROSITE PS00639 THIOL_PROTEASE_HIS coord: 431..441
Blast
BLAST of TCONS_00056152-protein vs. Swiss-Prot (Human)
Match:
CATL2 (Cathepsin L2 OS=Homo sapiens GN=CTSV PE=1 SV=2)
HSP 1 Score: 228.409 bits (581), Expect = 6.848e-71
Identity = 120/293 (40.96%), Postives = 180/293 (61.43%), Query Frame = 0
Query: 199 KKHTFKHNLRYINSMN----RKRLTYRLAVNHFADNSPSELRRLRGRLSGSNNKKHIKSNAKKFVSAVNVKDLPTQINWRLRGGVTPVKDQAVCGSCWSFGTTGTIEGAVFMKTGHLIRLSQQNLMDCSWGFGNNGCDGGEEFRAYEWIIKHGGIATELNYGQYLGVDSFCHFNQSQAGAVLSGYVNVTSGSEDALKEAIATKGPTSVGIDAAHLSFVFYANGVYYEPKCGNGPDDLDHAVLAAGYG----TLDGEDYWLVKNSWSTHWGNDGYVLMSR-KDNNCGVATAATY 482
++ ++ N++ I N + + + +A+N F D + E R++ G +K K F + + DLP ++WR +G VTPVK+Q CGSCW+F TG +EG +F KTG L+ LS+QNL+DCS GN GC+GG RA++++ ++GG+ +E +Y Y+ VD C + + A +G+ V G E AL +A+AT GP SV +DA H SF FY +G+Y+EP C + +LDH VL GYG + YWLVKNSW WG++GYV +++ K+N+CG+ATAA+Y
Sbjct: 48 RRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRK-----GKVFREPLFL-DLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESY-PYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSS--KNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASY 331
The following BLAST results are available for this feature:
BLAST of TCONS_00056152-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (
Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens) )
Total hits: 1
K M T Y F K K L L Q S L S K T I Q R G D L G E Y G Q H Y M I A P M T N E E V I N V Q T C F T L N G T Q D A V V E P Q Q A L P D T S K F I H K G M K N W D N R N V D V W E L V D T H G I K I N R Y T L Y V D S Q T L H P V F Y E M L G Y N S L L G S H F D E Y K L Y Y T I F A E D F P V D V F N I P T D M K C S G F P G P G H E A R I V A N P M K E F I Y P E D H S H L H Q M Y S D F V K K F S K Q N V G E E K K H T F K H N L R Y I N S M N R K R L T Y R L A V N H F A D N S P S E L R R L R G R L S G S N N K K H I K S N A K K F V S A V N V K D L P T Q I N W R L R G G V T P V K D Q A V C G S C W S F G T T G T I E G A V F M K T G H L I R L S Q Q N L M D C S W G F G N N G C D G G E E F R A Y E W I I K H G G I A T E L N Y G Q Y L G V D S F C H F N Q S Q A G A V L S G Y V N V T S G S E D A L K E A I A T K G P T S V G I D A A H L S F V F Y A N G V Y Y E P K C G N G P D D L D H A V L A A G Y G T L D G E D Y W L V K N S W S T H W G N D G Y V L M S R K D N N C G V A T A A T Y V E L K 50 100 150 200 250 300 350 400 450 Expect = 6.85e-71 / Id = 40.96 Sequence CATL2
Match Name E-value Identity Description
CATL2 6.848e-71 40.96 Cathepsin L2 OS=Homo sapiens GN=CTSV PE=1 SV=2 [more]
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