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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00057210-protein ID=TCONS_00057210-protein|Name=TCONS_00057210-protein|organism=Clytia hemisphaerica|type=polypeptide|length=881bp
MEEEVATLEMLQKVVDMKIQHLKGVRDKQHHEARSEIITSEISDLEGKLM
VLFASQIKSKSKIVNQEHAARFYPKLSQFLYVVDIDEEMRETLVNRCSLV
EELFEFSNERLAGIFYVHDDDEMKKKKLDGQYKRLRAARNIVKDYVVRLQ
NGEKRSELPWNSQWHEMAPDSPASVRSSIASVGHLSVFNYGPNEDLSNFK
SRSIPPSPSPARSVSSIPRSRSDDANVGQRIHRGSTSSAGSSSSTSRYMV
KSEKIRRKNKPGIITIPPSTDGETDSDHSKSRSSSITSSQSPRTPTLPSN
SNMGHSIKHRFSGKQLLISIACDYCTRVMLFGLKCKHCGFKCHKKCSRKV
PPSCSLPPQMLDYFKKKVDNESRAQVDDRKKLSLPPNLMLGKDSLVPIKR
TNSEPSNFANRVRSIDKHMSSSHGSLMHNTVGNGASSSMVGAGSHRGASA
DTYSTASSTSSISSSTFHSDSPLGTPGVGGDGHEMGNNERFPFFPDGDNL
VGEISLVNSLISTTSTVSEASTNTLIDSKCSSDTKSSSTLSIQEEENSVD
DLDDQISDIRKHVKLRNHGSLMSEWVIPFSQIEIGDHIGVGRVGKVYKAK
WHGECALKVLYLENPTTEEKNDFKYKVQVLRRTRHENLVLFMGACMEPAT
LAIVCSFIKGMSLYSHIHVHETKFDDVKIISIVQQIAQGMSYLHARKIVH
KDLKTKNVFLEHNQNRIVITDFGLISIADVKVTNTRKNHLMLPKGWLCYQ
APEIIRHLSAHDPGCEVLYYTRESDIYAFGTIWFELLAGDWPFAKQSNQS
IIWQIGKGVKQSLSDPKLTREGLYVTRETKDIISMTWALDPENRPQFSAL
LKAFERLPKKRLIRSPSQPTYLTRTANALLI Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0035556 | intracellular signal transduction |
| GO:0006468 | protein phosphorylation |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004672 | protein kinase activity |
| GO:0005524 | ATP binding |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 542..562 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 656..869
e-value: 1.4E-37
score: 128.0 |
| None | No IPR available | GENE3D | 3.30.60.20 | | coord: 301..360
e-value: 1.0E-9
score: 37.6 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 562..655
e-value: 1.1E-19
score: 69.7 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 527..551 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 199..306 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 419..486 |
| None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 298..358 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SMART | SM00109 | c1_12 | coord: 309..354
e-value: 1.6E-6
score: 37.7 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PFAM | PF00130 | C1_1 | coord: 309..355
e-value: 5.5E-7
score: 29.3 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 309..354 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 308..354
score: 12.239 |
| IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 309..354
e-value: 1.4797E-10
score: 57.1168 |
| IPR000719 | Protein kinase domain | SMART | SM00220 | serkin_6 | coord: 582..854
e-value: 2.6E-35
score: 133.3 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 582..857
score: 38.025 |
| IPR025561 | Kinase suppressor of RAS, SAM-like domain | PFAM | PF13543 | KSR1-SAM | coord: 8..124
e-value: 8.6E-14
score: 51.7 |
| IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | PFAM | PF07714 | Pkinase_Tyr | coord: 582..853
e-value: 5.8E-50
score: 169.9 |
| IPR008271 | Serine/threonine-protein kinase, active site | PROSITE | PS00108 | PROTEIN_KINASE_ST | coord: 698..710 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 572..867 |
Blast
BLAST of TCONS_00057210-protein vs. Swiss-Prot (Human)
Match: KSR2 (Kinase suppressor of Ras 2 OS=Homo sapiens GN=KSR2 PE=1 SV=2) HSP 1 Score: 279.641 bits (714), Expect = 1.725e-80 Identity = 141/335 (42.09%), Postives = 209/335 (62.39%), Query Frame = 0
Query: 543 QEEENSVDDLDDQISDIRKHVKLRNHGSL-MSEWVIPFSQIEIGDHIGVGRVGKVYKAKWHGECALKVLYLENPTTEEKNDFKYKVQVLRRTRHENLVLFMGACMEPATLAIVCSFIKGMSLYSHIHVHETKFDDVKIISIVQQIAQGMSYLHARKIVHKDLKTKNVFLEHNQNRIVITDFGLISIADVKVTNTRKNHLMLPKGWLCYQAPEIIRHLSAHDPGCEVLYYTRESDIYAFGTIWFELLAGDWPFAKQSNQSIIWQIGKGVKQSLSDPKLTREGLYVTRETKDIISMTWALDPENRPQFSALLKAFERLPKKRLIRSPSQPTYLTRTA 876
+E E+ ++++ + R + + S+ + EW IPF Q+EIG+ IG GR G+VY +WHGE A++++ +E ++ FK +V R+TRHEN+VLFMGACM P LAI+ S KG +LYS + + D K I Q+I +GM YLHA+ I+HKDLK+KNVF ++ ++VITDFGL SI+ V R++ L + GWLC+ APEIIR LS D + L +++ SD++A GTIW+EL A +WPF Q ++IIWQ+G G+K +LS + + +E DI+ WA + E RP F+ L+ E+LPK+ R S P + ++A
Sbjct: 626 EESEDDFEEMNLSLLSARSFPRKASQTSIFLQEWDIPFEQLEIGELIGKGRFGQVYHGRWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVF--YDNGKVVITDFGLFSISGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSP-DTEEDKLPFSKHSDVFALGTIWYELHAREWPFKTQPAEAIIWQMGTGMKPNLSQ-------IGMGKEISDILLFCWAFEQEERPTFTKLMDMLEKLPKRN--RRLSHPGHFWKSA 948
The following BLAST results are available for this feature:
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