TCONS_00057574-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00057574-protein
Unique Name	TCONS_00057574-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1264

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00057574-protein ID=TCONS_00057574-protein|Name=TCONS_00057574-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1264bp
MPYMNSGAPDHDLATQFRRLLATPKDLRSREEVQTIYGHLREIKVVSKLP
EGEVRKMAENARYEVHESNQTIYQAQDIATCWYILLSGSLYLEGAIYHPG
CSFGQVTQTGRRISDCLILERSEMIVIDYPQNAVQLPFGTKPNNLGDDKS
LTHQDPNLAEMSQMLVNNEPYFNQMARKQEQRPSKQHQKQHRGSRLDEPD
LDLSGMKETIVDLDSDDEDDVMPSESAVVRDIVRDCLEKEPSERTENDIH
ILMDFMQHLPAFNSLSHNIKLEMCKVMVFAVVEKAGATVMSDKEEMDSWS
VILNGSVDILIEGEAPVSLHLGDAFGVHTEKKKMYHKGTMRTRVDDCQFV
CIAQEDYWRIFSQGEASCRKVEEEGEVVMVTEHRVTDGGSRQGQVVIKGT
PDRLLDHLMEDHSVIDPTYVEDFLLTYVVFFNKPHDIASKLLKWFERPQL
KDKVTRVMLLWVNNHYADFEGDVYMETSMQRFEYLLEAKKMVGQLRLLNM
ACSAKSKPRIITLQRPSKDSRLDFSICGGKDRGFPIFVSKVDTVSKASDL
GLKRGDQILEVNGHSFENITGPKAIDVLMSHAHLCVIVKTNTIGFKEVIQ
PSIKKTKSNSSLTKSNGTLEVPKGQASVQRSSSAVSSSNSKQSGKSMTME
DHHHQSHRGSKGHDWTDFSGSQTLPKKAFKRFKLNPFQRSPSNTDLTRTQ
FQSEAGEEIIRYAKSGQEKVNQSNQMFGQLPNAYGEDSLDLNSQVIKVYR
GDHTSRFFVLTKDTSAREVVQTAIDAFGITDHSTKSYFLCQVTVTEDGLI
KQRRLNDALNNLANRISLNGRYYIKSSISEGPLPDEVAQEIAREANLTLL
QLSPLEIAKELSLQDFDLFKNVDSREYIYNLFEEKNERKSKNLRSVEQTT
NVEMYWVISEICNEHNITKRVKLLKYFIKVAKFCKDFKNYNSMYALISGL
ENTAVSRLKNTWERLPQKHDKIFEELKDLMDPSRNMSKYRNMFTGERCYP
PLIPWFPIVKKDITFLHLGNKTHVDGLVNFEKLRMIAKEVRRVCKFCAIG
YDPYKMDSMQDNVGDTSNVAQSVVSIMGNSPNPSRRGRGSLAMKDPKKAY
EEFQTSRRIRQYLEKLSGKSYNEKEMMEMSYNCEPPVSSQNSLARQKKPS
SPLPSAGDLKRKEERSSKSSTDSTRSVEYSEPKQADSSTPRKKQAPHQWN
DDHHPTGRGPLYSESSNSISSRNGSLKSITSIGSRSLPPSYQEFRSESPL
NYDDDDHHGQVSMV

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_036304	XLOC_036304	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00057574	TCONS_00057574	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000159	RA_dom
IPR001478	PDZ
IPR000651	Ras-like_Gua-exchang_fac_N
IPR001895	RASGEF_cat_dom
IPR014710	RmlC-like_jellyroll
IPR019804	Ras_G-nucl-exch_fac_CS
IPR000595	cNMP-bd_dom
IPR023578	Ras_GEF_dom
IPR018490	cNMP-bd-like
IPR029071	Ubiquitin-rel_dom

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding
GO:0005085	guanyl-nucleotide exchange factor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
biological_process	GO:0007264	small GTPase mediated signal transduction
molecular_function	GO:0005085	guanyl-nucleotide exchange factor activity
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 879..899
None	No IPR available	GENE3D	3.10.20.90		coord: 740..822 e-value: 2.8E-8 score: 33.8
None	No IPR available	GENE3D	2.30.42.10		coord: 502..593 e-value: 3.4E-14 score: 52.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 604..670
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1132..1264
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1076..1099
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 176..204
None	No IPR available	CDD	cd00038	CAP_ED	coord: 261..363 e-value: 3.2641E-6 score: 45.7798
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 508..589 e-value: 6.45832E-16 score: 74.1402
None	No IPR available	CDD	cd00038	CAP_ED	coord: 47..136 e-value: 1.9384E-6 score: 46.5502
IPR000159	Ras-associating (RA) domain	SMART	SM00314	RA_5	coord: 742..829 e-value: 2.9E-6 score: 36.8
IPR000159	Ras-associating (RA) domain	PFAM	PF00788	RA	coord: 743..818 e-value: 9.6E-6 score: 26.1
IPR000159	Ras-associating (RA) domain	PROSITE	PS50200	RA	coord: 742..829 score: 17.81
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 520..592 e-value: 7.7E-10 score: 48.7
IPR001478	PDZ domain	PFAM	PF00595	PDZ	coord: 512..581 e-value: 5.1E-8 score: 33.1
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 510..578 score: 14.375
IPR001478	PDZ domain	SUPERFAMILY	50156	PDZ domain-like	coord: 505..585
IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal	SMART	SM00229	rasgefn_5	coord: 392..505 e-value: 4.2E-21 score: 86.1
IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal	PFAM	PF00618	RasGEF_N	coord: 396..473 e-value: 4.1E-9 score: 36.5
IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal	PROSITE	PS50212	RASGEF_NTER	coord: 392..506 score: 17.63
IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal	CDD	cd06224	REM	coord: 400..499 e-value: 1.45548E-14 score: 71.2895
IPR001895	Ras guanine-nucleotide exchange factors catalytic domain	SMART	SM00147	RasGEF_3	coord: 849..1137 e-value: 9.7E-69 score: 244.4
IPR001895	Ras guanine-nucleotide exchange factors catalytic domain	PFAM	PF00617	RasGEF	coord: 856..1034 e-value: 3.7E-49 score: 167.2
IPR001895	Ras guanine-nucleotide exchange factors catalytic domain	GENE3D	1.10.840.10		coord: 841..1162 e-value: 1.9E-78 score: 263.0
IPR001895	Ras guanine-nucleotide exchange factors catalytic domain	PROSITE	PS50009	RASGEF_CAT	coord: 853..1084 score: 59.755
IPR001895	Ras guanine-nucleotide exchange factors catalytic domain	CDD	cd00155	RasGEF	coord: 849..1069 e-value: 3.09305E-62 score: 212.498
IPR014710	RmlC-like jelly roll fold	GENE3D	2.60.120.10		coord: 176..383 e-value: 6.8E-19 score: 67.4 coord: 10..175 e-value: 4.5E-14 score: 51.7
IPR019804	Ras guanine-nucleotide exchange factor, conserved site	PROSITE	PS00720	RASGEF	coord: 1003..1032
IPR000595	Cyclic nucleotide-binding domain	PROSITE	PS50042	CNMP_BINDING_3	coord: 261..326 score: 9.924
IPR023578	Ras guanine nucleotide exchange factor domain	SUPERFAMILY	48366	Ras GEF	coord: 835..1053 coord: 363..526 coord: 1104..1147
IPR018490	Cyclic nucleotide-binding-like	SUPERFAMILY	51206	cAMP-binding domain-like	coord: 18..127
IPR018490	Cyclic nucleotide-binding-like	SUPERFAMILY	51206	cAMP-binding domain-like	coord: 239..363
IPR029071	Ubiquitin-related domain	SUPERFAMILY	54236	Ubiquitin-like	coord: 743..807

Blast

[Close]

BLAST of TCONS_00057574-protein vs. Swiss-Prot (Human)
Match: RPGF2 (Rap guanine nucleotide exchange factor 2 OS=Homo sapiens GN=RAPGEF2 PE=1 SV=1)

HSP 1 Score: 807.749 bits (2085), Expect = 0.000e+0
Identity = 438/989 (44.29%), Postives = 650/989 (65.72%), Query Frame = 0

Query:  200 DLDLSGMKETIVDLDSDDEDDVM--PSESAVVRDIVRDCLEKEPSERTENDIHILMDFMQHLPAFNSLSHNIKLEMCKVMVFAVVEKAGATVMSDKEEMDSWSVILNGSVDILI-EGEAPVSLHLGDAFGVHTEKKKMYHKGTMRTRVDDCQFVCIAQEDYWRIFSQGEASCRKVEEEGEVVMVTEHRVTD-GGSRQGQVVIKGTPDRLLDHLMEDHSVIDPTYVEDFLLTYVVFFNKPHDIASKLLKWFERPQLKDKVTRVMLLWVNNHYADFEGDVYMETSMQRFEYLLEAKKMVGQLRLLNMACSAKSKPRIITLQRPSKDSRLDFSICGGKDRGFPIFVSKVDTVSKASDLGLKRGDQILEVNGHSFENITGPKAIDVLMSHAHLCVIVKTNTIGFKEVIQPSIKKTKSNSSLTKSNGTLEVPKGQASVQRSSSAVSSSNSKQSGKSMTMEDHHHQSHRGSKGHDWTDFSGSQTLPKKAFKRFKLNPFQRSPSN-TDLTRTQFQSEAGEEIIRYAKSGQEKVNQSNQMFGQLPNAYGED--------SLDLNSQVIKVYRGDHTSRFFVLTKDTSAREVVQTAIDAFGITDHSTKSYFLCQVTVTEDGLIKQRRLNDALNNLANRISLNGRYYIKSSI-SEGPLPDEVAQEIAREANLTLLQLSPLEIAKELSLQDFDLFKNVDSREYIYNLFEEKNERKSKNLRSVEQTTNVEMYWVISEICNEHNITKRVKLLKYFIKVAKFCKDFKNYNSMYALISGLENTAVSRLKNTWERLPQKHDKIFEELKDLMDPSRNMSKYRNMFTGERCYPPLIPWFPIVKKDITFLHLGNKTHVDGLVNFEKLRMIAKEVRRVCKFCAIGYDPYKMDSMQD----NVGDTS--NVAQSVVSIMGNSPNPSRRGRGSLAMKDPKKAYEEFQTSRRIRQYLEKLSGKSYNEKEMMEMSYNCEPPVSSQNSLARQKKP----SSPL-PSAGDLKRKE 1163
            D+DLSG+ ET VD + DD+++ +   S+  + RDIVRDCLEK+P +RT++DI  L++FM  LPAF +++ +++ E+C VMVFAVVE+AG  V++D EE+DSWSVILNGSV++   +G+A + L +G++FGV     K Y KG MRT+VDDCQFVCIAQ+DY RI +Q E + +KVEEEGE+VMV EHR  D  G+R+G +VIKGT +RL  HL+E+HSV+DPT++EDFLLTY  F + P ++  KLL+WF  P L+DKVTRV+LLWVNNH+ DFEGD  M   ++ FE  LE +KM G LRLLN+AC+AK+K R++TL +PS+++ L F + GG ++GF IFV  VD+ SKA++ GLKRGDQILEVNG +FENI   KA+++L ++ HL + VKTN   FKE++        +  S  K NG   +PK    ++++S       +    + + +E  + +S   + G       G   L KK   + +++   + P N   + ++Q  S  G   +R  K     +  S  +    P+             + DL  QV++V++ D  SR+ +++KDT+A+EVV  AI  F +T  +   Y LC+V+VT +G+IKQRRL D L+ LA+RI L+GRYY+K+++ +E    DE AQE+ RE+ ++LLQLS +E+A +LS+++F+LF+N++  EYI +LF+ +++    NL+  E+  N E +WV SEI  E N  KR+K++K+FIK+A  C++ KN+NSM+A+ISGL    V+RL+ TWE+LP K++K+F++L+DL DPSRNM+KYRN+   +   PP+IP FP++KKD+TFLH GN + VDGLVNFEKLRMIAKE+R V +  ++  DP  M   +     ++G  S  +   +V+ +     +  R  R S    + KK YE+ Q +R+++QYL  L  +  +E+ +  +S  CEP  ++       KKP    +SP+ P AG  ++ +
Sbjct:   72 DMDLSGLPETAVDSEDDDDEEDIERASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQLPAFANMTMSVRRELCAVMVFAVVERAGTIVLNDGEELDSWSVILNGSVEVTYPDGKAEI-LCMGNSFGVSPTMDKEYMKGVMRTKVDDCQFVCIAQQDYCRILNQVEKNMQKVEEEGEIVMVKEHRELDRTGTRKGHIVIKGTSERLTMHLVEEHSVVDPTFIEDFLLTYRTFLSSPMEVGKKLLEWFNDPSLRDKVTRVVLLWVNNHFNDFEGDPAMTRFLEEFENNLEREKMGGHLRLLNIACAAKAKRRLMTLTKPSREAPLPFILLGGSEKGFGIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFVFKELL--------TRLSEEKRNGAPHLPK-IGDIKKASRYSIPDLAVDVEQVIGLEKVNKKSKANTVG-------GRNKL-KKILDKTRISILPQKPYNDIGIGQSQDDSIVG---LRQTKHIPTALPVSGTLSSSNPDLLQSHHRILDFSATPDLPDQVLRVFKADQQSRYIMISKDTTAKEVVIQAIREFAVT-ATPDQYSLCEVSVTPEGVIKQRRLPDQLSKLADRIQLSGRYYLKNNMETETLCSDEDAQELLRESQISLLQLSTVEVATQLSMRNFELFRNIEPTEYIDDLFKLRSKTSCANLKRFEEVINQETFWVASEILRETNQLKRMKIIKHFIKIALHCRECKNFNSMFAIISGLNLAPVARLRTTWEKLPNKYEKLFQDLQDLFDPSRNMAKYRNVLNSQNLQPPIIPLFPVIKKDLTFLHEGNDSKVDGLVNFEKLRMIAKEIRHVGRMASVNMDPALMFRTRKKKWRSLGSLSQGSTNATVLDVAQTGGHKKRVRRSSFL--NAKKLYEDAQMARKVKQYLSNLELE-MDEESLQTLSLQCEPATNTLPKNPGDKKPVKSETSPVAPRAGSQQKAQ 1035

The following BLAST results are available for this feature:

BLAST of TCONS_00057574-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00057574-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
RPGF2	0.000e+0	44.29	Rap guanine nucleotide exchange factor 2 OS=Homo s...	[more]

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TCONS_00057574-protein (polypeptide) - C. hemisphaerica