TCONS_00058495-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00058495-protein
Unique NameTCONS_00058495-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length438

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00058495-protein ID=TCONS_00058495-protein|Name=TCONS_00058495-protein|organism=Clytia hemisphaerica|type=polypeptide|length=438bp
MPEGPEHFKAAAFINKHCQDRSFTGKIVKSEVNHRNPEIDCQYETYTVSA
KARGKEVMVTVTNLTLDEKKQQSIKKKGIVKLEPVENKSEHFSIVFRFGM
SGCFRFTDADNLPKHSHLRFFSIDGMVLSFEDVRRFGKWKLTDTFSADRG
PDPVYEYIDFRKNVLNNIKNRIFQKSICELLHNQKYFNGIGNYLRAEILY
RCKIPPFTKSFDVFENLAIEKEEPKRKAKGNDGDFDILEYCSLVPFEVMV
LEGGGYDKSEKDSDYSLFENWLQCYYNKDMNNLVDHDGRTMWFQGEPGPL
VPTGEKAKARHNAKVIVPTEDNKKKTKEKSKKNTKKKAESKRSLTKGHVQ
PKKKLAHGRKKGNIKKEENADLVEECDNKDSSKTPTSLKSTKKKGPGNRK
RSIKHERGKIEATDVEVKDEKVIKIDDSHLRRSSRLKK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_036853XLOC_036853Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00058495TCONS_00058495Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR012319FPG_cat
IPR015371Endonuclease-VIII_DNA-bd
IPR015886DNA_glyclase/AP_lyase_DNA-bd
IPR010979Ribosomal_S13-like_H2TH
Vocabulary: Molecular Function
TermDefinition
GO:0003906DNA-(apurinic or apyrimidinic site) lyase activity
GO:0003684damaged DNA binding
GO:0016799hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0008270zinc ion binding
GO:0003676nucleic acid binding
Vocabulary: Biological Process
TermDefinition
GO:0006284base-excision repair
GO:0006289nucleotide-excision repair
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006284 base-excision repair
biological_process GO:0006289 nucleotide-excision repair
molecular_function GO:0003684 damaged DNA binding
molecular_function GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity
molecular_function GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
molecular_function GO:0003676 nucleic acid binding
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR012319Formamidopyrimidine-DNA glycosylase, catalytic domainSMARTSM00898Fapy_DNA_glyco_2coord: 2..140
e-value: 1.4E-7
score: 37.0
IPR012319Formamidopyrimidine-DNA glycosylase, catalytic domainPFAMPF01149Fapy_DNA_glycocoord: 1..139
e-value: 5.0E-17
score: 62.5
IPR012319Formamidopyrimidine-DNA glycosylase, catalytic domainPROSITEPS51068FPG_CATcoord: 2..137
score: 14.382
IPR012319Formamidopyrimidine-DNA glycosylase, catalytic domainSUPERFAMILY81624N-terminal domain of MutM-like DNA repair proteinscoord: 2..144
NoneNo IPR availableGENE3D3.20.190.10coord: 2..150
e-value: 1.2E-17
score: 63.7
NoneNo IPR availableGENE3D1.10.8.50coord: 221..294
e-value: 5.5E-4
score: 19.4
coord: 151..220
e-value: 6.2E-16
score: 58.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 295..414
NoneNo IPR availableSUPERFAMILY57716Glucocorticoid receptor-like (DNA-binding domain)coord: 261..302
IPR015371Endonuclease VIII-like 1, DNA bindingPFAMPF09292Neil1-DNA_bindcoord: 264..302
e-value: 1.4E-23
score: 82.3
IPR015886DNA glycosylase/AP lyase, H2TH DNA-bindingPFAMPF06831H2THcoord: 150..209
e-value: 6.0E-7
score: 29.3
IPR010979Ribosomal protein S13-like, H2THSUPERFAMILY46946S13-like H2TH domaincoord: 149..215

Blast
[Close]
BLAST of TCONS_00058495-protein vs. Swiss-Prot (Human)
Match: NEIL1 (Endonuclease 8-like 1 OS=Homo sapiens GN=NEIL1 PE=1 SV=3)

HSP 1 Score: 268.47 bits (685), Expect = 2.889e-86
Identity = 141/353 (39.94%), Postives = 203/353 (57.51%), Query Frame = 0 
Query:    1 MPEGPEHFKAAAFINKHCQDRSFTGKIVKSEVNHRNPEIDCQYETYTVSAKARGKEVMVTVTNLTLDEKKQQSIKKKGIVKLEPVENKSEHFSIVFRFGMSGCFRFTDADNLPKHSHLRFFSIDG---MVLSFEDVRRFGKWKLTDTFSADRGPDPVYEYIDFRKNVLNNIKNRIFQKSICELLHNQKYFNGIGNYLRAEILYRCKIPPFTKSFDVFENLAIEKEEPK----RKAKGNDGDFDILEYCSLVPFEVMVLEGGGYDKSEKDSDYSLFENWLQCYYNKDMNNLVDHDGRTMWFQGEPGPLVPTGEKAKARHNAKVIVPTEDNKKKTKEKSKKNTKKKAESKRSLTK 346
            MPEGPE   A+ F+N+ C+   F G + KS V+ RNPE+  +   Y +SA ARGKE+ + ++ L   + +Q                  E  ++VFRFGMSG F+    + LP+H+HLRF++      + L F D+RRFG+W L   +   RGP  + EY  FR+NVL N+ ++ F + ICE L +Q++FNGIGNYLRAEILYR KIPPF K+  V E L   +  P+    +K +    + D+LE C  VP EV+ L G GY     + D++ F  WL+CY    M++L D  GRT+WFQG+PGPL P G K++ + +    +  ED  +     SK  ++ +  +KR L K
Sbjct:    1 MPEGPELHLASQFVNEACRALVFGGCVEKSSVS-RNPEVPFESSAYRISASARGKELRLILSPLPGAQPQQ------------------EPLALVFRFGMSGSFQLVPREELPRHAHLRFYTAPPGPRLALCFVDIRRFGRWDLGGKWQPGRGPCVLQEYQQFRENVLRNLADKAFDRPICEALLDQRFFNGIGNYLRAEILYRLKIPPFEKARSVLEALQQHRPSPELTLSQKIRTKLQNPDLLELCHSVPKEVVQLGGKGYGSESGEEDFAAFRAWLRCYGMPGMSSLQDRHGRTIWFQGDPGPLAPKGRKSRKKKSKATQLSPEDRVEDALPPSKAPSRTR-RAKRDLPK 333
The following BLAST results are available for this feature:
BLAST of TCONS_00058495-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NEIL12.889e-8639.94Endonuclease 8-like 1 OS=Homo sapiens GN=NEIL1 PE=... [more]
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