TCONS_00058879-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00058879-protein
Unique Name	TCONS_00058879-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	448

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00058879-protein ID=TCONS_00058879-protein|Name=TCONS_00058879-protein|organism=Clytia hemisphaerica|type=polypeptide|length=448bp
MQLWMKMKIGFLYLWMNMCWISLVNGVDESELSPILKKILDPLIYEKSSI
PIKDDQKPIQATVSIFTNDMIPRENLDMHFTYDFFFTIEWNDYRLKHNLS
SSNDTVLPFDYTILKDIWAPNLYFAQTKDGLVPDFPQPNVMVTIAKDGDV
RLNYKIILTLFCAMDLTFYPFDIQKCNLNLESYSYGLHFLNISWGYFIYD
KERVRTQDFNKVEIKTDQTVSTYHTIGQWKGLIIEFTFYRNAPLYLIRDF
LPCTLIVMLSWVNFWINFRSTPARTALGITTVLTIVTMTNNVRNNSPSSS
GLFRSIDFYMLVCNMFVFAALVEGALVGMTAPNEKYVKSTFKNQVKKVLR
NTRNKSKKLDMADVVKRRLKEESEKEKEEEEDEEKITSTIIQRVRPITTE
TFKLGPFHFYKGEIHIIDRICRFLFPFLFLVFNFTFFIFHMLKDESVL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_037088	XLOC_037088	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00058879	TCONS_00058879	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006028	GABAA/Glycine_rcpt
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 359..386
None	No IPR available	GENE3D	1.20.58.390		coord: 246..448 e-value: 1.1E-33 score: 115.5
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha	PRINTS	PR00253	GABAARECEPTR	coord: 271..292 score: 50.88 coord: 306..327 score: 49.12 coord: 420..440 score: 32.03 coord: 245..265 score: 48.42
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 116..127 score: 28.88 coord: 162..176 score: 49.53 coord: 81..97 score: 34.68 coord: 236..248 score: 24.75
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 251..383 e-value: 2.2E-22 score: 80.2
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 245..442
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 35..222 e-value: 3.0E-33 score: 115.0
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 27..245 e-value: 1.9E-36 score: 125.0
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 35..241
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 162..176

Blast

[Close]

BLAST of TCONS_00058879-protein vs. Swiss-Prot (Human)
Match: GLRA2 (Glycine receptor subunit alpha-2 OS=Homo sapiens GN=GLRA2 PE=1 SV=1)

HSP 1 Score: 176.022 bits (445), Expect = 4.501e-50
Identity = 121/403 (30.02%), Postives = 191/403 (47.39%), Query Frame = 0

Query:   58 PIQATVSIFTNDMIPRENLDMHFTYDFFFTIEWNDYRLKHNLSSSNDTVLPFDYTILKDIWAPNLYFAQTKDGLVPDFPQPNVMVTIAKDGDVRLNYKIILTLFCAMDLTFYPFDIQKCNLNLESYSYGLHFLNISW--GYFIYDKERVRTQDFNKVEIKTDQTVSTYHTIGQWKGLIIEFTFYRNAPLYLIRDFLPCTLIVMLSWVNFWINFRSTPARTALGITTVLTIVTMTNNVRNNSPSSSGLFRSIDFYMLVCNMFVFAALVEGALVGMTAPNEK-----YVKSTFKNQVKKVLRNTRNKSKKLDMADVVKRR-----LKEESEKEKEEEEDEEKITSTIIQRVRPITTETFKLGPFHFYKGEIHIIDRICRFLFPFLFLVFNFTFFI-FHMLKDESV 447
            P+  T +IF N         M +  + F   +WND RL +  S   D  L  D ++L  IW P+L+FA  K     D    N ++ I+K+G V  + ++ LTL C MDL  +P D+Q C + LES+ Y ++ L   W     +   E +    F   E K     + ++  G++  + ++F   R    YLI+ ++P  LIV+LSWV+FWIN  + PAR ALGITTVLT+ T ++  R + P  S   ++ID +M VC +FVFAAL+E A V   +   K       +   +N+ + V R +R       M   ++ +         +    +  +D + I    + R +                     ID I R  FP  FL+FN  ++I + +++ E V
Sbjct:   70 PVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAY--SEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVS-YVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKR--------------------IDTISRAAFPLAFLIFNIFYWITYKIIRHEDV 449

The following BLAST results are available for this feature:

BLAST of TCONS_00058879-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00058879-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
GLRA2	4.501e-50	30.02	Glycine receptor subunit alpha-2 OS=Homo sapiens G...	[more]

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TCONS_00058879-protein (polypeptide) - C. hemisphaerica