TCONS_00059751-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00059751-protein
Unique NameTCONS_00059751-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length155

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00059751-protein ID=TCONS_00059751-protein|Name=TCONS_00059751-protein|organism=Clytia hemisphaerica|type=polypeptide|length=155bp
MTMIEESGIELQGKRAVVVGRSKIVGMPMSMLLTWANATVTICHSRTQNL
EDIVREADVLVAACGRPKMIKGSWIKQGAVVIDCGINSIEDASRKSGRRL
VGDVDYDEAKRRASYITPVPGGVGPMTVCMLMKNTLESAKRHLNLQDEKR
EEAAK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_037580XLOC_037580Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00059751TCONS_00059751Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000672THF_DH/CycHdrlase
IPR020631THF_DH/CycHdrlase_NAD-bd_dom
IPR020867THF_DH/CycHdrlase_CS
IPR016040NAD(P)-bd_dom
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
Vocabulary: Molecular Function
TermDefinition
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0003824catalytic activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0003824 catalytic activity
molecular_function GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000672Tetrahydrofolate dehydrogenase/cyclohydrolasePRINTSPR00085THFDHDRGNASEcoord: 99..115
score: 50.0
coord: 9..29
score: 59.52
coord: 58..87
score: 54.74
coord: 116..134
score: 82.19
NoneNo IPR availableGENE3D3.40.50.720coord: 1..124
e-value: 4.4E-38
score: 129.9
NoneNo IPR availableCDDcd01080NAD_bind_m-THF_DH_Cyclohydcoord: 1..140
e-value: 8.96932E-82
score: 240.15
IPR020631Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domainPFAMPF02882THF_DHG_CYH_Ccoord: 1..142
e-value: 6.7E-63
score: 210.7
IPR020867Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved sitePROSITEPS00767THF_DHG_CYH_2coord: 120..128
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 1..142

Blast
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BLAST of TCONS_00059751-protein vs. Swiss-Prot (Human)
Match: C1TC (C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3)

HSP 1 Score: 196.052 bits (497), Expect = 6.044e-59
Identity = 90/143 (62.94%), Postives = 116/143 (81.12%), Query Frame = 0 
Query:    1 MTMIEESGIELQGKRAVVVGRSKIVGMPMSMLLTWANATVTICHSRTQNLEDIVREADVLVAACGRPKMIKGSWIKQGAVVIDCGINSIEDASRKSGRRLVGDVDYDEAKRRASYITPVPGGVGPMTVCMLMKNTLESAKRHL 143
            + +I+E+G+ + G+ AVVVGRSKIVG PM  LL W NATVT CHS+T +L++ V + D+LV A G+P+M+KG WIK GA+VIDCGIN + D  + +GR++VGDV YDEAK RAS+ITPVPGGVGPMTV MLM++T+ESAKR L
Sbjct:  153 LELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFL 295
The following BLAST results are available for this feature:
BLAST of TCONS_00059751-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
C1TC6.044e-5962.94C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo... [more]
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