TCONS_00061961-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00061961-protein
Unique Name	TCONS_00061961-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1159

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00061961-protein ID=TCONS_00061961-protein|Name=TCONS_00061961-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1159bp
MSSTLLAKRSISPESVSVNGTALPPHYHPRDEFSDNELSGAKSTVDIEQM
FRARSSLDEAEKNYSVEIKDLNAEIPSNQNVDINKVAADKMHPHLHPVEE
KFNLKYAISLFKTIPFPSPKIEELYRRYFFHLNQHFINWFLVILIVTCIC
EIGLHFHFNRTGSFRYTRGIFLVVQVTVFAALLSIINWNGSSGRLLVLVS
YIIVFFNCLMTIFNSVPLEGDIHGVTKSMNFVIFAIYMTYVMLPLQFRMS
ICCGMLITTTHLITSVASQASTQKDVWWLIATNILIYIAVNLAGIFSHYP
AEQAQREAFLETRGFVETRLKLQRENQEQERLLLSVLPRHVAMEMKADIE
GELEESMFSKIYIQRHANVSILFADIEGFTQLASQCTAHELVKTLNELFA
RFDQLAVKNHCMRIKILGDCYYCVSGLPEPRPDHAHCCINMGLDVIEAIG
IVREAVGVKLNMRVGIHTGKVHCGVLGLKKWQYDVWSNDVTIASHMESGG
KPGLIHVTEAVCEEIKEEYSIEDGEGYKRDVYLKEHNIKSFFIVPSADKQ
KERQLSRNTKRSTTVANQYNVTPQGTQQAPNNGSARPEGVPNGVNNQNSQ
PFAKRFFEGVEEDDGSQELKEKKMRERLGLTMTTMSSEDEVNEFLERAID
ARNVEHLKEENVRPVILKFRKQEYENKYCEEVDSLFIPHMMFIFVVFLFI
IIIVVLVFPRTTKTLLLFTSVFCLLLPTILFSIFHKMEKISRLFSPKIVK
NQSLYRVLSITVIFLLYISATGTLFICPEQPPSIHSCIYNSSTTTPVELH
RDAIPGLADEYCVYPQYITYIISLAMITAANSLNCLSTSKFLIILAVALF
YSIAIPLKFKPLYDWHDSLAHCLSEGMSNQQFVPLYIHSISSVIYLFVGL
VSHTYMHENISRLDFLWKAQATQERDEMNDKRKYNKKLLYNILPVHVAEH
FLKDNNEDLYAQACSSVAVLFSNICNFSEFYMELEATGDGMECLRVLNQI
IVDFDNILQDPKFKTIEKIKTIGETYMAASGLNLQSAEELQNCDHVEELA
AFAMKMDDTLDEMNKNAFNNFKLKSGLSFGPVVAGVIGAKKPQYDIWGDT
VNVASRMYSTGKPNCIQVTQSVYNLLSKRGFTFECRGLVAVKGKGKMVTY
WLLKGKEGS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_038843	XLOC_038843	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00061961	TCONS_00061961	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001054	A/G_cyclase
IPR032628	AC_N
IPR009398	Adcy_conserved_dom
IPR030672	Adcy
IPR018297	A/G_cyclase_CS
IPR029787	Nucleotide_cyclase

Vocabulary: **Biological Process**
Term	Definition
GO:0009190	cyclic nucleotide biosynthetic process
GO:0035556	intracellular signal transduction
GO:0006171	cAMP biosynthetic process

Vocabulary: **Molecular Function**
Term	Definition
GO:0016849	phosphorus-oxygen lyase activity
GO:0004016	adenylate cyclase activity

Vocabulary: **Cellular Component**
Term	Definition
GO:0005886	plasma membrane

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006171	cAMP biosynthetic process
biological_process	GO:0009190	cyclic nucleotide biosynthetic process
biological_process	GO:0035556	intracellular signal transduction
cellular_component	GO:0005886	plasma membrane
molecular_function	GO:0004016	adenylate cyclase activity
molecular_function	GO:0016849	phosphorus-oxygen lyase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	SMART	SM00044	cyc_6	coord: 930..1137 e-value: 1.7E-41 score: 153.9 coord: 324..523 e-value: 1.6E-67 score: 240.3
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	GENE3D	3.30.70.1230		coord: 952..1158 e-value: 2.7E-58 score: 196.2
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	PFAM	PF00211	Guanylate_cyc	coord: 362..522 e-value: 4.2E-57 score: 192.6 coord: 960..1152 e-value: 9.8E-56 score: 188.2
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	GENE3D	3.30.70.1230		coord: 355..554 e-value: 9.3E-66 score: 220.5
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	PROSITE	PS50125	GUANYLATE_CYCLASE_2	coord: 370..497 score: 41.672
IPR001054	Adenylyl cyclase class-3/4/guanylyl cyclase	PROSITE	PS50125	GUANYLATE_CYCLASE_2	coord: 968..1108 score: 36.581
IPR032628	Adenylate cyclase, N-terminal	PFAM	PF16214	AC_N	coord: 108..358 e-value: 6.5E-49 score: 167.1
IPR009398	Adenylate cyclase, conserved domain	PFAM	PF06327	DUF1053	coord: 632..686 e-value: 4.9E-8 score: 33.4
IPR030672	Adenylate cyclase	PIRSF	PIRSF039050	Ade_cyc	coord: 74..1159 e-value: 0.0 score: 1132.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 552..598
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..39
None	No IPR available	CDD	cd07302	CHD	coord: 368..517 e-value: 1.53824E-52 score: 182.394
None	No IPR available	CDD	cd07302	CHD	coord: 967..1152 e-value: 8.38698E-51 score: 177.386
IPR018297	Adenylyl cyclase class-4/guanylyl cyclase, conserved site	PROSITE	PS00452	GUANYLATE_CYCLASE_1	coord: 474..497
IPR029787	Nucleotide cyclase	SUPERFAMILY	55073	Nucleotide cyclase	coord: 965..1153
IPR029787	Nucleotide cyclase	SUPERFAMILY	55073	Nucleotide cyclase	coord: 359..524

Blast

[Close]

BLAST of TCONS_00061961-protein vs. Swiss-Prot (Human)
Match: ADCY6 (Adenylate cyclase type 6 OS=Homo sapiens GN=ADCY6 PE=1 SV=2)

HSP 1 Score: 830.861 bits (2145), Expect = 0.000e+0
Identity = 455/1100 (41.36%), Postives = 681/1100 (61.91%), Query Frame = 0

Query:   93 PHLHPVEEKFNLKYAISLFKTIPFPSPKIEELYRRYFFHLNQHFINWFLVILIVTCICEIGLHFHFNRTGSFRYTRGIFLVVQVTVFAALLSIINWNGSSGRLLVLVSYIIVFFNCLMTIFNSVPLEGDIHGVTKSMNFVIFAIYMTYVMLPLQFRMSICCGMLITTTHLITSVASQASTQKD-VWWLIATNILIYIAVNLAGIFSHYPAEQAQREAFLETRGFVETRLKLQRENQEQERLLLSVLPRHVAMEMKADIEGELEESMFSKIYIQRHANVSILFADIEGFTQLASQCTAHELVKTLNELFARFDQLAVKNHCMRIKILGDCYYCVSGLPEPRPDHAHCCINMGLDVIEAIGIVREAVGVKLNMRVGIHTGKVHCGVLGLKKWQYDVWSNDVTIASHMESGGKPGLIHVTEAVCEEIKEEYSIEDGEGYKRDVYLKEHNIKSFFIVPSADKQKERQLSRNTKRSTTVANQYNVTPQGTQQAPNNGSARPEGVPNGVNNQNSQPFAKRFFEGVEEDDGSQELKEKKMRERLGLTMTTMSSEDEVNEFLERAIDARNVEHLKEENVRPVILKFRKQEYENKYCEEVDSLFIPHMMFIFVVFLFIIIIVVLVFPRTTKTLLLFTSVFCLLLPTILF-------SIFHK-MEKISRLFSPKIVKNQSLYRVLSITVIFLLYISATGTLFICPEQPPSIHSCIYNSSTTTPVELHRDAIPGL-------------ADEYCVYPQYITYIISLAMITAANSLNCLSTSKF-LIILAVALFYSIAIPLKFKPLYDWHDSLAHCLSEGMSNQQFVPL--------YIHSISSVIYLFVGLVSHTYMH----ENISRLDFLWKAQATQERDEMNDKRKYNKKLLYNILPVHVAEHFL--KDNNEDLYAQACSSVAVLFSNICNFSEFYMELEATGDGMECLRVLNQIIVDFDNILQDPKFKTIEKIKTIGETYMAASGLNLQSAEELQNCDHVEELAAFAMKMDDTLDEMNKNAFNNFKLKSGLSFGPVVAGVIGAKKPQYDIWGDTVNVASRMYSTGKPNCIQVTQSVYNLLSKRGFTFECRGLVAVKGKGKMVTYWLLKG 1155
            P   P   +   +  + +F++  F S K+E LY+RYFF +NQ  +   + +L++     +  H    R    +      L     +F  L+ + N +      + +VSY+++    L  +     L  D    +  +   +F +Y+ Y +LP++ R ++  G+ ++T HLI  +A Q +     +W  +  N+L+++  N+ GI +HYPAE +QR+AF ETRG+++ RL LQ EN++QERLLLSVLP+HVAMEMK DI  + E+ MF KIYIQ+H NVSILFADIEGFT LASQCTA ELV TLNELFARFD+LA +NHC+RIKILGDCYYCVSGLPE R DHAHCC+ MG+D+IEAI +VRE  GV +NMRVGIH+G+VHCGVLGL+KWQ+DVWSNDVT+A+HME+GG+ G IH+T A  + +  +Y +E G G +R+ YLKE +I++F I+ ++ K+KE +      + T   +   + P   +  P+   +R          ++S+ F +    G+  DD S++ +          T   ++ EDEV+EFL RAIDAR+++ L++++VR  +L F++++ E KY  +VD  F  ++    +VF FI  I +L+FP +T  L ++ S+F LLL T+L        S+F K ++++SR     IV++++    + I  + L++ SA   +F C   P  I SC       TP ++    +  L                 C +P+Y    + L+++ ++  L+  S  K  +I +   ++  + +      ++D +D L        SN+ F  L         +  ++ VI L   L    Y+H    E+ +RLDFLWK QAT E++EM + + YN++LL+NILP  VA HFL  +  N++LY Q+C  VAV+F++I NFSEFY+ELEA  +G+ECLR+LN+II DFD I+ + +F+ +EKIKTIG TYMAASGLN  + +++    H+  LA +AM++ + +  +N+++FNNF++K GL+ GPVVAGVIGA+KPQYDIWG+TVNV+SRM STG P+ IQVT  +Y +L+ +G+  ECRG+V VKGKG+M TY+L  G
Sbjct:  108 PDAVPRSGRSCWRRLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARP---QPAYVALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVL--GILAAVQVGGALAADPRSPSAGLWCPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLI--LAWQLNRGDAFLWKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMP---RWVPDRAFSR---------TKDSKAFRQM---GI--DDSSKDNRG---------TQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSCGSLFPKALQRLSR----SIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTP--IRSCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPVILLVFALA--LYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGR-SHITALADYAMRLMEQMKHINEHSFNNFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNGG 1165

The following BLAST results are available for this feature:

BLAST of TCONS_00061961-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00061961-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ADCY6	0.000e+0	41.36	Adenylate cyclase type 6 OS=Homo sapiens GN=ADCY6 ...	[more]

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TCONS_00061961-protein (polypeptide) - C. hemisphaerica