TCONS_00063185-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00063185-protein
Unique NameTCONS_00063185-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1040

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00063185-protein ID=TCONS_00063185-protein|Name=TCONS_00063185-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1040bp
MPEEQDFTQVSSYTNWMKKMSDKIKKHNELKNTQMTATINNDIKKNENSS
KMNNENRSRSEKKGKEEIYEKSWAVCQCHIEGEEDFADEKRRNITSSLQE
DRQKRIRRHINSTTSVEETESIADDFSSSPSTSLCCNICLNSSSNLTTKT
TSTSTSSSKKHRKRKGRNAHRVLLNNHPSQKQVYSSYSTGQQKINKRSSA
PGDTRFNGGSRTHERIIENSFDNDVFEDCFVENKFAVKKSFSYDNAILKN
SFAREKENLRKTLSGEKPIRDGDGPFVIDNFTSLNHLQKQQEKRDFIVYK
NGAQNDNRNSSVPIDRRPQSEYGRRKHVTYDVKTLYRVNSDAPPRSWTLD
ISRSSDSDDNMLFPKLRKNFKFGTKPNGRAASDGCTTQGSRKGSQRRTTS
AEFIQEFLGPADTPVNARLFGGKKGVQYEIERAKSYGYVIHPCSKLRQYW
DLLIMTMLVLNMMVLPLDIAFFDDNSLISFHVISDTLCMVDIILNFRTGY
HLRKEKHEFELGHKKIAIHYLKTWFTLDLISSLPLHYILLAVSGQNVTLG
LKGASRALKFLKVAKLLNLLKLLRLSRIIRGIAQYEEVYCVTTGFIRYIK
LVCMMLMVAHWNGCLHFLVPMLQDFPEKCWVQECKIVNEPWYVQYGWALF
KTLSHMLCIGYGRYIPALLDEALITIFSMVTGATFYALFIAHSMAFIIQR
DSSKSTYQEKIKQIEEYMHHRNVPPEIKKRISNYFEHKYHQGRFFDEQAI
MSVIGKPLREEIVHHTCKDLVESVPFLKAASPHFVTAVLDRLTFDVYLSG
DAVIKEGTTGDEMFFVRKGCLDVSVKGRLIYQLKGGEYFGDICMLTDDTK
HIITVEARTTCDLFSLSYKTLATLLIQYPEVRPILEQAALNQLMNITQTI
ELLNAAREKQKEKNGSNGPYGSNNNSPVVKKRSTLSRQSSLNQLKELING
TVETLAAKIKTFKEENDVIAERFEDSMTSQEMMPSQDNTPCKQKKDESAI
IVENELEEGTHKNKDSDPTTGSDHGLDDPTKDDFHVSTSF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_039592XLOC_039592Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00063185TCONS_00063185Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000595cNMP-bd_dom
IPR005821Ion_trans_dom
IPR014710RmlC-like_jellyroll
IPR013621Ion_trans_N
IPR018488cNMP-bd_CS
IPR018490cNMP-bd-like
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
Vocabulary: Biological Process
TermDefinition
GO:0055085transmembrane transport
GO:0006811ion transport
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
biological_process GO:0055085 transmembrane transport
cellular_component GO:0016020 membrane
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 893..913
NoneNo IPR availableGENE3D1.10.287.70coord: 595..704
e-value: 5.3E-10
score: 38.4
NoneNo IPR availableGENE3D1.20.120.350coord: 446..589
e-value: 1.5E-10
score: 40.4
NoneNo IPR availableGENE3D1.10.287.630coord: 705..762
e-value: 1.4E-21
score: 76.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 147..211
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 908..936
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 373..397
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 974..1040
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 37..64
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 99..130
NoneNo IPR availableCDDcd00038CAP_EDcoord: 776..882
e-value: 1.87094E-18
score: 81.9885
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 442..697
IPR000595Cyclic nucleotide-binding domainSMARTSM00100cnmp_10coord: 776..893
e-value: 1.2E-14
score: 64.7
IPR000595Cyclic nucleotide-binding domainPFAMPF00027cNMP_bindingcoord: 797..877
e-value: 1.8E-11
score: 43.8
IPR000595Cyclic nucleotide-binding domainPROSITEPS50042CNMP_BINDING_3coord: 776..892
score: 21.719
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 448..692
e-value: 4.1E-18
score: 65.4
IPR014710RmlC-like jelly roll foldGENE3D2.60.120.10coord: 763..906
e-value: 2.6E-26
score: 91.5
IPR013621Ion transport N-terminalPFAMPF08412Ion_trans_Ncoord: 405..445
e-value: 1.4E-8
score: 34.1
IPR018488Cyclic nucleotide-binding, conserved sitePROSITEPS00888CNMP_BINDING_1coord: 803..819
IPR018490Cyclic nucleotide-binding-likeSUPERFAMILY51206cAMP-binding domain-likecoord: 702..892

Blast
BLAST of TCONS_00063185-protein vs. Swiss-Prot (Human)
Match: HCN3 (Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 OS=Homo sapiens GN=HCN3 PE=2 SV=2)

HSP 1 Score: 421.394 bits (1082), Expect = 2.612e-133
Identity = 227/521 (43.57%), Postives = 336/521 (64.49%), Query Frame = 0
Query:  407 FLGPADTPVNARLFGGKKGVQYEIERAKSYG-YVIHPCSKLRQYWDLLIMTMLVLNMMVLPLDIAFF-DDNS--LISFHVISDTLCMVDIILNFRTGYHLRKEKHEFELGHKKIAIHYLKTWFTLDLISSLPLHYILLAVSGQ-NVTLGLKGASRALKFLKVAKLLNLLKLLRLSRIIRGIAQYEEVYCVT----TGFIRYIKLVCMMLMVAHWNGCLHFLVPMLQDFPEKCWVQECKIVNEPWYVQYGWALFKTLSHMLCIGYGRYIPALLDEALITIFSMVTGATFYALFIAHSMAFIIQRDSSKSTYQEKIKQIEEYMHHRNVPPEIKKRISNYFEHKYHQGRFFDEQAIMSVIGKPLREEIVHHTCKDLVESVPFLKAASPHFVTAVLDRLTFDVYLSGDAVIKEGTTGDEMFFVRKGCLDVSVKGRLIYQLKGGEYFGDICMLTDDTKHIITVEARTTCDLFSLSYKTLATLLIQYPEVRPILEQAALNQLMNITQTIELLNAAREKQKEKNGSNG 918
             L P     + R+FG  K V+ E ER KS G ++IHP S  R YWDL+++ ++V N++VLP+ I FF ++NS   I F+V+SDT  ++D++LNFRTG  + +E  E  L  + I   YL+TWF +DLISS+P+ YI L V  +  +   +   +RAL+ ++  K+L+LL+LLRLSR+IR I Q+EE++ +T    +  +R   L+ MML++ HW+GCL FLVPMLQDFP  CWV    +VN  W  QY  ALFK +SHMLCIGYG+  P  + +  +T+ SM+ GAT YA+FI H+ A I   DSS+  YQEK KQ+E+YM    +P + ++RI  Y+EH+Y QG+ FDE++I+  + +PLREEI++ TC+ LV  +P    A P FVTAVL +L F+V+  GD V++EG+ G +M+F++ G L V  +G    +L  G YFG+IC+LT   +   +V A T C L+SLS      +L ++P +R   E  A+++L+ I +   +L   R++ +   GS+G
Sbjct:   52 LLQPTVNKFSLRVFGSHKAVEIEQERVKSAGAWIIHPYSDFRFYWDLIMLLLMVGNLIVLPVGITFFKEENSPPWIVFNVLSDTFFLLDLVLNFRTGI-VVEEGAEILLAPRAIRTRYLRTWFLVDLISSIPVDYIFLVVELEPRLDAEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPMLQDFPPDCWVSINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRY-QGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLARGARDTRLTDGSYFGEICLLTRG-RRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAFETVAMDRLLRIGKKNSILQ--RKRSEPSPGSSG 567          
The following BLAST results are available for this feature:
BLAST of TCONS_00063185-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
HCN32.612e-13343.57Potassium/sodium hyperpolarization-activated cycli... [more]
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