TCONS_00066421-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00066421-protein
Unique NameTCONS_00066421-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length622

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00066421-protein ID=TCONS_00066421-protein|Name=TCONS_00066421-protein|organism=Clytia hemisphaerica|type=polypeptide|length=622bp
MELCNSGFLFLYSQSKVQSLLITKDSPIDKDLQKLKEVASVDINIEQLLV
VPAYSEVGDDVIALFCLFNKIGAKTGFTKLDEELMQMVVKNCRHIVCNAL
DWKSQLIIQRQNESLLEISKTLFSHLDDVSILLHKIMEEARNLTNAERCS
LFLVDHNRGELIAKVFDGIESENSSEIRIPITNGIAGYVATTGETLNIKD
AYSHPLFYKEVDQKTGFKTRHILCFPIRSVSEQIIGVAQLCNKLNGNCFT
KFDEERTLGFAIFVGLSLVQSLLYKKATDAKQRSKLANELMLYHMMVSQE
EIDSYVKVAMPTKDSLHPDMDKFSFMPRISFAETDSIKVVLSMFNDLNVI
KRWKVSESTLVRFILTVRRGYRDVPYHNWTHAWTVAHFSYTLLKKTNALD
YLSDLEVFVLLVSCLCHDIDHRGTNNSFQISSQSVLASLYSSAGSVLERH
HFAQAMCIVQTEHNNVFESLSSTDYKRALDLMQKMILATDLANHFKISKQ
LDELASTGIQKDEAAHRELLLSLFMTTSDLSDQTKPWESAVKVSDLLYQE
FFSQGEMEKSLGYQPVKMMDKDLASIPDLQYSFLNNIAYPIYEKLSHFFP
ETNCILGNIKENQKQWSKIKEG
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_041561XLOC_041561Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00066421TCONS_00066421Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR023088PDEase
IPR003607HD/PDEase_dom
IPR003018GAF
IPR029016GAF_dom-like
IPR002073PDEase_catalytic_dom
IPR023174PDEase_CS
Vocabulary: Molecular Function
TermDefinition
GO:0008081phosphoric diester hydrolase activity
GO:0005515protein binding
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activity
Vocabulary: Biological Process
TermDefinition
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007165 signal transduction
molecular_function GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function GO:0008081 phosphoric diester hydrolase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR0230883'5'-cyclic nucleotide phosphodiesterasePRINTSPR00387PDIESTERASE1coord: 542..558
score: 42.59
coord: 403..416
score: 32.29
coord: 417..432
score: 61.0
coord: 372..385
score: 54.0
coord: 525..538
score: 53.71
coord: 445..461
score: 45.06
IPR003607HD/PDEase domainSMARTSM00471hd_13coord: 374..543
e-value: 3.1E-9
score: 46.7
IPR003018GAF domainSMARTSM00065gaf_1coord: 128..278
e-value: 1.7E-34
score: 130.6
IPR003018GAF domainPFAMPF01590GAFcoord: 130..266
e-value: 4.9E-14
score: 53.0
IPR029016GAF domain-likeGENE3D3.30.450.40coord: 18..92
e-value: 0.086
score: 12.3
IPR029016GAF domain-likeGENE3D3.30.450.40coord: 108..292
e-value: 1.8E-35
score: 121.8
IPR029016GAF domain-likeSUPERFAMILY55781GAF domain-likecoord: 42..127
IPR029016GAF domain-likeSUPERFAMILY55781GAF domain-likecoord: 109..294
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainPFAMPF00233PDEase_Icoord: 376..609
e-value: 7.8E-76
score: 254.8
IPR0020733'5'-cyclic nucleotide phosphodiesterase, catalytic domainGENE3D1.10.1300.10coord: 295..622
e-value: 2.0E-102
score: 342.1
IPR0231743'5'-cyclic nucleotide phosphodiesterase, conserved sitePROSITEPS00126PDEASE_Icoord: 417..428
NoneNo IPR availableCDDcd00077HDccoord: 376..552
e-value: 3.18329E-14
score: 69.2905
NoneNo IPR availableSUPERFAMILY109604HD-domain/PDEase-likecoord: 313..621

Blast
[Close]
BLAST of TCONS_00066421-protein vs. Swiss-Prot (Human)
Match: PDE2A (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Homo sapiens GN=PDE2A PE=1 SV=1)

HSP 1 Score: 603.208 bits (1554), Expect = 0.000e+0
Identity = 285/591 (48.22%), Postives = 416/591 (70.39%), Query Frame = 0 
Query:   30 KDLQKLKEVASVDINIEQLLVVPAYSEVGDDVIALFCLFNKIGAKTGFTKLDEELMQMVVKNCRHIVCNALDWKSQLIIQRQNESLLEISKTLFSHLDDVSILLHKIMEEARNLTNAERCSLFLVDHNRGELIAKVFDG-IESENSSEIRIPITNGIAGYVATTGETLNIKDAYSHPLFYKEVDQKTGFKTRHILCFPIRSVSEQIIGVAQLCNKLNGNCFTKFDEERTLGFAIFVGLSLVQSLLYKKATDAKQRSKLANELMLYHMMVSQEEIDSYVKVAMPTKDSLHPDMDKFSFMPRISFAETDSIKVVLSMFNDLNVIKRWKVSESTLVRFILTVRRGYRDVPYHNWTHAWTVAHFSYTLLKKTNALDYLSDLEVFVLLVSCLCHDIDHRGTNNSFQISSQSVLASLYSSAGSVLERHHFAQAMCIVQTEHNNVFESLSSTDYKRALDLMQKMILATDLANHFKISKQLDELASTGIQKDEAAHRELLLSLFMTTSDLSDQTKPWESAVKVSDLLYQEFFSQGEMEKSLGYQPVKMMDKDLASIPDLQYSFLNNIAYPIYEKLSHFFPETNCILGNIKENQKQWSKI 619
            +D+Q+L+ +   ++  + +L VP  S   D V+AL C FNK+     FT  DE ++Q        ++ + L ++ +  ++ + ++LL+++K LF+HLDDVS+LL +I+ EARNL+NAE CS+FL+D N  EL+AKVFDG +  + S EIRIP   GIAG+VATTG+ LNI DAY+HPLFY+ VD  TGF+TR+ILCFPI++ ++++IGVA+L NK+NG  F+KFDE+    F+I+ G+S+  SLLYKK  +A+ RS LANE+M+YHM VS +E    +   +    ++  +   F++ PR S  E D+   +LSM  D+N I  +K+   TL RF L V++GYRD PYHNW HA++V+HF Y L K     +YL D+E+F L +SC+CHD+DHRGTNNSFQ++S+SVLA+LYSS GSV+ERHHFAQA+ I+ T   N+F+  S  DY+R LDLM+ +ILATDLA+H +I K L ++A  G  ++   H  LLL L MT+ DLSDQTK W++  K+++L+Y+EFFSQG++EK++G +P++MMD++ A IP+LQ SF+ +IA PIY+ L   FP+   +   +  N++ W+K+
Sbjct:  314 EDVQQLQSMLGCEL--QAMLCVPVISRATDQVVALACAFNKLEGDL-FTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQN--ELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPR-SLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKV 898
The following BLAST results are available for this feature:
BLAST of TCONS_00066421-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PDE2A0.000e+048.22cGMP-dependent 3',5'-cyclic phosphodiesterase OS=H... [more]
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