TCONS_00066578-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00066578-protein
Unique NameTCONS_00066578-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length735

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00066578-protein ID=TCONS_00066578-protein|Name=TCONS_00066578-protein|organism=Clytia hemisphaerica|type=polypeptide|length=735bp
MAGTGFDQSEVYFTDPFGTEDSGPDPNANVNEIKKHFRDFIREFHESNFV
FPYRDQLKRNYNLGQYYLEVSLDDLRSYDELLVDKLLKNPTEHIAIFEEA
AKEIADEVTKPRPLGDEEVQDIQVTLRSEANPVGLRDLKSENVSKLVKIP
GIIISASTIRVKATKITIQCRGCKNTLPNIGLKPGLEGYAMPRSCPTDQT
GKPAPCPLDPFFILPDKCKCVDFQVLKLQESPDAVPNGEMPRHLQLYCDR
YLTENVVPGNRLTVTGIYSIKKTGPQKKKDNSGGGVGIRKPYIRVLGIHV
ETDGPGRSSGSIHFTPQDEEEFRRLASRPDAFDVISRSIAPSIYGSEDIK
KSIACLLFGGSRKRLPDGLTRRGDINVLLLGDPGTAKSQLLKFVEKVSPI
GVYTSGKGSSAAGLTASVIRDPVSRNFIMEGGAMVLADGGVVCIDEFDKM
RQDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKG
DQNIDFMPTILSRFDTIFIVKDEHDQQKDIRLAKHVMQVHLNAAQASSDG
VEADLSLNFLKKYIDYCRRKCGPRLSQSAAEKLQNQYVLMRTGARTQEQQ
SNKRNSIPITVRQLEAIVRISESLAKMRLQPFALEADVDEALRLFQVSTL
DAALSGGLSGAEGFTPEEDIEEVRRLETLLKKRFAIGSQVSEQRIISDFQ
RQKFSEKAISTVIHIMLRRGELEHKYQRKVLYRVR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_041635XLOC_041635Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00066578TCONS_00066578Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001208MCM_dom
IPR008048MCM5
IPR031327MCM
IPR033762MCM_OB
IPR027925MCM_N
IPR018525MCM_CS
IPR027417P-loop_NTPase
IPR012340NA-bd_OB-fold
Vocabulary: Biological Process
TermDefinition
GO:0006270DNA replication initiation
GO:0006260DNA replication
Vocabulary: Molecular Function
TermDefinition
GO:0003677DNA binding
GO:0005524ATP binding
GO:0003688DNA replication origin binding
GO:0003678DNA helicase activity
GO:0003682chromatin binding
Vocabulary: Cellular Component
TermDefinition
GO:0005634nucleus
GO:0042555MCM complex
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006260 DNA replication
biological_process GO:0006270 DNA replication initiation
cellular_component GO:0042555 MCM complex
cellular_component GO:0005634 nucleus
molecular_function GO:0005524 ATP binding
molecular_function GO:0003682 chromatin binding
molecular_function GO:0003677 DNA binding
molecular_function GO:0003678 DNA helicase activity
molecular_function GO:0003688 DNA replication origin binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001208MCM domainPRINTSPR01657MCMFAMILYcoord: 432..446
score: 77.92
coord: 372..387
score: 76.41
coord: 484..496
score: 61.79
coord: 510..518
score: 69.53
coord: 460..473
score: 85.02
IPR001208MCM domainPFAMPF00493MCMcoord: 318..648
e-value: 3.7E-137
score: 456.8
IPR001208MCM domainPROSITEPS50051MCM_2coord: 331..536
score: 92.498
IPR008048DNA replication licensing factor McmPRINTSPR01661MCMPROTEIN5coord: 136..151
score: 65.91
coord: 643..660
score: 75.76
coord: 289..301
score: 64.34
coord: 567..582
score: 72.16
coord: 162..174
score: 60.84
IPR031327Mini-chromosome maintenance proteinSMARTSM00350mcmcoord: 131..650
e-value: 4.0E-281
score: 949.9
NoneNo IPR availableGENE3D3.30.1640.10coord: 19..129
e-value: 3.2E-23
score: 81.5
NoneNo IPR availableGENE3D3.40.50.300coord: 315..544
e-value: 1.9E-16
score: 59.4
NoneNo IPR availableGENE3D2.40.50.140coord: 133..302
e-value: 1.5E-39
score: 134.8
NoneNo IPR availableCDDcd00009AAAcoord: 376..520
e-value: 1.47848E-4
score: 40.2071
IPR033762MCM OB domainPFAMPF17207MCM_OBcoord: 135..271
e-value: 1.1E-37
score: 128.5
IPR027925MCM N-terminal domainPFAMPF14551MCM_Ncoord: 34..125
e-value: 4.9E-18
score: 65.5
IPR018525Mini-chromosome maintenance, conserved sitePROSITEPS00847MCM_1coord: 440..448
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 341..650
IPR012340Nucleic acid-binding, OB-foldSUPERFAMILY50249Nucleic acid-binding proteinscoord: 36..295

Blast
BLAST of TCONS_00066578-protein vs. Swiss-Prot (Human)
Match: MCM5 (DNA replication licensing factor MCM5 OS=Homo sapiens GN=MCM5 PE=1 SV=5)

HSP 1 Score: 1063.14 bits (2748), Expect = 0.000e+0
Identity = 503/737 (68.25%), Postives = 618/737 (83.85%), Query Frame = 0
Query:    4 TGFDQSEVYFTDPFGTEDSGPDPNANVNEIKKHFRDFIREFH----ESNFVFPYRDQLKRNYNLGQYYLEVSLDDLRSYDELLVDKLLKNPTEHIAIFEEAAKEIADEVTKPRPLGDEEVQDIQVTLRSEANPVGLRDLKSENVSKLVKIPGIIISASTIRVKATKITIQCRGCKNTLPNIGLKPGLEGYAMPRSCPTDQTGKPAPCPLDPFFILPDKCKCVDFQVLKLQESPDAVPNGEMPRHLQLYCDRYLTENVVPGNRLTVTGIYSIKKTGPQKKKDNSGGGVGIRKPYIRVLGIHVETDGPGRS-SGSIHFTPQDEEEFRRLASRPDAFDVISRSIAPSIYGSEDIKKSIACLLFGGSRKRLPDGLTRRGDINVLLLGDPGTAKSQLLKFVEKVSPIGVYTSGKGSSAAGLTASVIRDPVSRNFIMEGGAMVLADGGVVCIDEFDKMRQDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKGDQNIDFMPTILSRFDTIFIVKDEHDQQKDIRLAKHVMQVHLNAAQASSDGVEADLSLNFLKKYIDYCRRKCGPRLSQSAAEKLQNQYVLMRTGARTQEQQSNKRNSIPITVRQLEAIVRISESLAKMRLQPFALEADVDEALRLFQVSTLDAALSGGLSGAEGFTPEEDIEEVRRLETLLKKRFAIGSQVSEQRIISDFQRQKFSEKAISTVIHIMLRRGELEHKYQRKVLYRVR 735
            +GFD   ++++D FG +    +  A  +++++ F++F+R++      + F F YRD+LKR+YNLG+Y++EV ++DL S+DE L D L K P EH+ + EEAAKE+ADEVT+PRP G+E +QDIQV L+S+A+P  +R LKS+ +S LVKIPGIII+AS +R KAT+I+IQCR C+NTL NI ++PGLEGYA+PR C TDQ G+P  CPLDP+FI+PDKCKCVDFQ LKLQE PDAVP+GEMPRH+QLYCDRYL + VVPGNR+T+ GIYSIKK G    +     GVGIR  YIRVLGI V+TDG GRS +G++  +PQ+EEEFRRLA+ P+ ++VIS+SIAPSI+G  D+KK+IACLLFGGSRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK SPIGVYTSGKGSSAAGLTASV+RDP SRNFIMEGGAMVLADGGVVCIDEFDKMR+DDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWD+TKG+ NIDFMPTILSRFD IFIVKDEH++++D+ LAKHV+ +H++A    +  VE ++ L  LKK+I YCR KCGPRLS  AAEKL+N+Y++MR+GAR  E+ S++R+SIPITVRQLEAIVRI+E+L+KM+LQPFA EADV+EALRLFQVSTLDAALSG LSG EGFT +ED E + R+E  LK+RFAIGSQVSE  II DF +QK+ E AI  V+ +MLRRGE++H+ QRKVLYR++
Sbjct:    2 SGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRP-KCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAV--SPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSAL-TQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK 734          
The following BLAST results are available for this feature:
BLAST of TCONS_00066578-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MCM50.000e+068.25DNA replication licensing factor MCM5 OS=Homo sapi... [more]
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