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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00066578-protein ID=TCONS_00066578-protein|Name=TCONS_00066578-protein|organism=Clytia hemisphaerica|type=polypeptide|length=735bp MAGTGFDQSEVYFTDPFGTEDSGPDPNANVNEIKKHFRDFIREFHESNFV FPYRDQLKRNYNLGQYYLEVSLDDLRSYDELLVDKLLKNPTEHIAIFEEA AKEIADEVTKPRPLGDEEVQDIQVTLRSEANPVGLRDLKSENVSKLVKIP GIIISASTIRVKATKITIQCRGCKNTLPNIGLKPGLEGYAMPRSCPTDQT GKPAPCPLDPFFILPDKCKCVDFQVLKLQESPDAVPNGEMPRHLQLYCDR YLTENVVPGNRLTVTGIYSIKKTGPQKKKDNSGGGVGIRKPYIRVLGIHV ETDGPGRSSGSIHFTPQDEEEFRRLASRPDAFDVISRSIAPSIYGSEDIK KSIACLLFGGSRKRLPDGLTRRGDINVLLLGDPGTAKSQLLKFVEKVSPI GVYTSGKGSSAAGLTASVIRDPVSRNFIMEGGAMVLADGGVVCIDEFDKM RQDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKG DQNIDFMPTILSRFDTIFIVKDEHDQQKDIRLAKHVMQVHLNAAQASSDG VEADLSLNFLKKYIDYCRRKCGPRLSQSAAEKLQNQYVLMRTGARTQEQQ SNKRNSIPITVRQLEAIVRISESLAKMRLQPFALEADVDEALRLFQVSTL DAALSGGLSGAEGFTPEEDIEEVRRLETLLKKRFAIGSQVSEQRIISDFQ RQKFSEKAISTVIHIMLRRGELEHKYQRKVLYRVR Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term | Definition |
GO:0006270 | DNA replication initiation |
GO:0006260 | DNA replication |
Vocabulary: Molecular Function
Term | Definition |
GO:0003677 | DNA binding |
GO:0005524 | ATP binding |
GO:0003688 | DNA replication origin binding |
GO:0003678 | DNA helicase activity |
GO:0003682 | chromatin binding |
Vocabulary: Cellular Component
Term | Definition |
GO:0005634 | nucleus |
GO:0042555 | MCM complex |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
biological_process |
GO:0006260 |
DNA replication |
biological_process |
GO:0006270 |
DNA replication initiation |
cellular_component |
GO:0042555 |
MCM complex |
cellular_component |
GO:0005634 |
nucleus |
molecular_function |
GO:0005524 |
ATP binding |
molecular_function |
GO:0003682 |
chromatin binding |
molecular_function |
GO:0003677 |
DNA binding |
molecular_function |
GO:0003678 |
DNA helicase activity |
molecular_function |
GO:0003688 |
DNA replication origin binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
IPR001208 | MCM domain | PRINTS | PR01657 | MCMFAMILY | coord: 432..446 score: 77.92 coord: 372..387 score: 76.41 coord: 484..496 score: 61.79 coord: 510..518 score: 69.53 coord: 460..473 score: 85.02 |
IPR001208 | MCM domain | PFAM | PF00493 | MCM | coord: 318..648 e-value: 3.7E-137 score: 456.8 |
IPR001208 | MCM domain | PROSITE | PS50051 | MCM_2 | coord: 331..536 score: 92.498 |
IPR008048 | DNA replication licensing factor Mcm | PRINTS | PR01661 | MCMPROTEIN5 | coord: 136..151 score: 65.91 coord: 643..660 score: 75.76 coord: 289..301 score: 64.34 coord: 567..582 score: 72.16 coord: 162..174 score: 60.84 |
IPR031327 | Mini-chromosome maintenance protein | SMART | SM00350 | mcm | coord: 131..650 e-value: 4.0E-281 score: 949.9 |
None | No IPR available | GENE3D | 3.30.1640.10 | | coord: 19..129 e-value: 3.2E-23 score: 81.5 |
None | No IPR available | GENE3D | 3.40.50.300 | | coord: 315..544 e-value: 1.9E-16 score: 59.4 |
None | No IPR available | GENE3D | 2.40.50.140 | | coord: 133..302 e-value: 1.5E-39 score: 134.8 |
None | No IPR available | CDD | cd00009 | AAA | coord: 376..520 e-value: 1.47848E-4 score: 40.2071 |
IPR033762 | MCM OB domain | PFAM | PF17207 | MCM_OB | coord: 135..271 e-value: 1.1E-37 score: 128.5 |
IPR027925 | MCM N-terminal domain | PFAM | PF14551 | MCM_N | coord: 34..125 e-value: 4.9E-18 score: 65.5 |
IPR018525 | Mini-chromosome maintenance, conserved site | PROSITE | PS00847 | MCM_1 | coord: 440..448 |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | SUPERFAMILY | 52540 | P-loop containing nucleoside triphosphate hydrolases | coord: 341..650 |
IPR012340 | Nucleic acid-binding, OB-fold | SUPERFAMILY | 50249 | Nucleic acid-binding proteins | coord: 36..295 |
Blast
BLAST of TCONS_00066578-protein vs. Swiss-Prot (Human)
Match: MCM5 (DNA replication licensing factor MCM5 OS=Homo sapiens GN=MCM5 PE=1 SV=5) HSP 1 Score: 1063.14 bits (2748), Expect = 0.000e+0 Identity = 503/737 (68.25%), Postives = 618/737 (83.85%), Query Frame = 0 Query: 4 TGFDQSEVYFTDPFGTEDSGPDPNANVNEIKKHFRDFIREFH----ESNFVFPYRDQLKRNYNLGQYYLEVSLDDLRSYDELLVDKLLKNPTEHIAIFEEAAKEIADEVTKPRPLGDEEVQDIQVTLRSEANPVGLRDLKSENVSKLVKIPGIIISASTIRVKATKITIQCRGCKNTLPNIGLKPGLEGYAMPRSCPTDQTGKPAPCPLDPFFILPDKCKCVDFQVLKLQESPDAVPNGEMPRHLQLYCDRYLTENVVPGNRLTVTGIYSIKKTGPQKKKDNSGGGVGIRKPYIRVLGIHVETDGPGRS-SGSIHFTPQDEEEFRRLASRPDAFDVISRSIAPSIYGSEDIKKSIACLLFGGSRKRLPDGLTRRGDINVLLLGDPGTAKSQLLKFVEKVSPIGVYTSGKGSSAAGLTASVIRDPVSRNFIMEGGAMVLADGGVVCIDEFDKMRQDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKGDQNIDFMPTILSRFDTIFIVKDEHDQQKDIRLAKHVMQVHLNAAQASSDGVEADLSLNFLKKYIDYCRRKCGPRLSQSAAEKLQNQYVLMRTGARTQEQQSNKRNSIPITVRQLEAIVRISESLAKMRLQPFALEADVDEALRLFQVSTLDAALSGGLSGAEGFTPEEDIEEVRRLETLLKKRFAIGSQVSEQRIISDFQRQKFSEKAISTVIHIMLRRGELEHKYQRKVLYRVR 735
+GFD ++++D FG + + A +++++ F++F+R++ + F F YRD+LKR+YNLG+Y++EV ++DL S+DE L D L K P EH+ + EEAAKE+ADEVT+PRP G+E +QDIQV L+S+A+P +R LKS+ +S LVKIPGIII+AS +R KAT+I+IQCR C+NTL NI ++PGLEGYA+PR C TDQ G+P CPLDP+FI+PDKCKCVDFQ LKLQE PDAVP+GEMPRH+QLYCDRYL + VVPGNR+T+ GIYSIKK G + GVGIR YIRVLGI V+TDG GRS +G++ +PQ+EEEFRRLA+ P+ ++VIS+SIAPSI+G D+KK+IACLLFGGSRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK SPIGVYTSGKGSSAAGLTASV+RDP SRNFIMEGGAMVLADGGVVCIDEFDKMR+DDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWD+TKG+ NIDFMPTILSRFD IFIVKDEH++++D+ LAKHV+ +H++A + VE ++ L LKK+I YCR KCGPRLS AAEKL+N+Y++MR+GAR E+ S++R+SIPITVRQLEAIVRI+E+L+KM+LQPFA EADV+EALRLFQVSTLDAALSG LSG EGFT +ED E + R+E LK+RFAIGSQVSE II DF +QK+ E AI V+ +MLRRGE++H+ QRKVLYR++
Sbjct: 2 SGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRP-KCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAV--SPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSAL-TQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK 734
The following BLAST results are available for this feature:
BLAST of TCONS_00066578-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 ( Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match Name | E-value | Identity | Description | |
MCM5 | 0.000e+0 | 68.25 | DNA replication licensing factor MCM5 OS=Homo sapi... | [more] |
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