TCONS_00068759-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00068759-protein
Unique Name	TCONS_00068759-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	552

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00068759-protein ID=TCONS_00068759-protein|Name=TCONS_00068759-protein|organism=Clytia hemisphaerica|type=polypeptide|length=552bp
MNQKNLLFIIRSILFDYSFVWISVFCFGKKMQIFVLIAFVLLKEVLSDTH
EDIYKILSESEMTIDEDLVRRSTTTRNTRAVDPYLLTMTPHNQDDDEMRL
VSHLLNNYNKEVRPVQNKSDAVQVIFGMAYTQLLDLEEKNQVLVSNVWIR
MRWFNHLLKWDPSDYGGIKSINLPPQLIWVPDIVLYNNAEETLGAGQMDQ
FKTKIILQHDGLNKWFAPTILRSRCSINVEFFPFDDQKCDLKFLSWTYDG
LRINITNSSPTADLATYLPSGEFELISAEAVRKITKYPCCDEPYPHVTFT
IHIRRKTLFYFNNLIVPCFLITALGLLTFVLPPATGERVTLVITTLLAMT
VFMLMIAEKTPTTSKVTPLIGKFFIASMVIIGLSLIATCIVLNLYECTRA
VESVPKPIRIIVLEYLAPFLRVDPPIQRKLARPRSNQQVDTAVHEKHGTT
EVTTGNGAWRFHDNFHPAHHHHHHHREETSRQRNVAVLPKEISEGIAVLS
ERAKQQEKFDELTEEWQAVAKVADRLFLIIFLLTIAITTVYIFVNRPDPD
SI

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_042881	XLOC_042881	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00068759	TCONS_00068759	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR002394	Nicotinic_acetylcholine_rcpt
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0022848	acetylcholine-gated cation-selective channel activity
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Cellular Component**
Term	Definition
GO:0045211	postsynaptic membrane
GO:0016021	integral component of membrane

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
cellular_component	GO:0045211	postsynaptic membrane
molecular_function	GO:0022848	acetylcholine-gated cation-selective channel activity
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002394	Nicotinic acetylcholine receptor	PRINTS	PR00254	NICOTINICR	coord: 205..223 score: 31.58 coord: 131..147 score: 43.2 coord: 165..179 score: 40.52
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 144..160 score: 27.63 coord: 177..188 score: 54.64 coord: 225..239 score: 49.53 coord: 301..313 score: 35.47
IPR006201	Neurotransmitter-gated ion-channel	TIGRFAM	TIGR00860	TIGR00860	coord: 94..543 e-value: 2.3E-93 score: 311.4
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 314..543 e-value: 1.6E-43 score: 149.4
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 307..544
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 84..312 e-value: 7.2E-72 score: 241.0
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 98..307 e-value: 7.5E-61 score: 205.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 96..306
None	No IPR available	GENE3D	1.20.58.390		coord: 313..551 e-value: 3.0E-43 score: 146.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 431..483
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 225..239

Blast

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BLAST of TCONS_00068759-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 323.168 bits (827), Expect = 1.408e-104
Identity = 174/481 (36.17%), Postives = 272/481 (56.55%), Query Frame = 0

Query:   93 QDDDEMRLVSHLLNNYNKEVRPVQNKSDAVQVIFGMAYTQLLDLEEKNQVLVSNVWIRMRWFNHLLKWDPSDYGGIKSINLPPQLIWVPDIVLYNNAEETLGAGQMDQFKTKIILQHDGLNKWFAPTILRSRCSINVEFFPFDDQKCDLKFLSWTYDGLRINITNSSPTADLATYLPSGEFELISAEAVRKITKYPCCDEPYPHVTFTIHIRRKTLFYFNNLIVPCFLITALGLLTFVLPPATGERVTLVITTLLAMTVFMLMIAEKTPTTSKVTPLIGKFFIASMVIIGLSLIATCIVLNLYECTRAVESVPKPIRIIVLEYLAPFLRVDPPIQRKL--ARPRSNQQVDTAVHEKHGTTEVTTGNG-----AWRFHDNFH-----------------PAHHHH-HHHREETSRQRNVAVLPKEISEGIAVLSERAKQQEKFDELTEEWQAVAKVADRLFLIIFLLTIAITTVYIFVNRPD 548
            Q + + +L   L+ NYN   RPV N S  + V F ++  Q++D++EKNQVL +N+W++M W +H L+W+ S+Y G+K++  P   IW PDI+LYN+A+E   A     F T +++   G  ++  P I +S C I+V +FPFD Q C LKF SW+Y G  +++      AD++ Y+P+GE++L+     R    Y CC EPYP VTFT+ +RR+TL+Y  NL++PC LI+AL LL F+LP  +GE+++L IT LL++TVFML++AE  P TS   PLI ++F ++M+I+GLS++ T IVL  +        +PK  R+I+L + A FLR+  P + K+  A     ++   A  E          NG      +R  D  H                 P H  H  H  +      ++A    +I E +  ++ R + Q++ + +  EW+  A V DRL L+ F +   I T+ I ++ P+
Sbjct:   22 QGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDA----TFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQE--ADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLA----KILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPN 492

The following BLAST results are available for this feature:

BLAST of TCONS_00068759-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00068759-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA7	1.408e-104	36.17	Neuronal acetylcholine receptor subunit alpha-7 OS...	[more]

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TCONS_00068759-protein (polypeptide) - C. hemisphaerica