TCONS_00052949 (transcript) - C. hemisphaerica

BLAST of TCONS_00052949 vs. Swiss-Prot (Human)
Match: NOTC1 (Neurogenic locus notch homolog protein 1 OS=Homo sapiens GN=NOTCH1 PE=1 SV=4)

HSP 1 Score: 218.009 bits (554), Expect = 3.861e-60
Identity = 187/490 (38.16%), Postives = 250/490 (51.02%), Query Frame = 2

Query:   32 QINLA-CNINPCQSGGICSPSSLVAAGYTCTCPTGFSGQTCTES--SCSGNPCATGSTCVPDASANGFSCTCTAGQSNPLC-NVADGCGTVSGENPCLNGGDCSLSNTLYAGYSCQCNGGFSGPMCKIS--ACSKNPCQNGGSCTAKPSSPGFECACVAPYTGAICQESICS-LQQPCKNGGSCAVASGTPGYQCTCANNGYTGPTCEA--SACDVNPCANGAQCNPSAAYPGYTCTCPVGFSGPTCSAS--ACDANPCKNGATCTPDGTALGYSCACVGGYSGSTCTASA--CDALPCFNGGTCIVDSSNDGFTCNCQPGYSGATCSQS--ACGPNPCQNGGSCQPDNSADGYTCTCEEGYFGVNCM--ASNCDMQPCQNGGSCEPDGSADGFTCTCEVGYFGVHCT--ASACTSHPCKYGGSCQPDGSDDG---YTCSCLTGFFGNQCE-LRSCVGSNPCQNGGLCFQQGISQACICNNGFTGSNCEV 1432
            +INL  C  +PC SG           GY C C  G++G  C  +   C+GNPC  G TC  +   NGF+C C  G  +P C +  + C +    NPC++G  C  S     GY C C+ G+SG  C I+   C  NPC NGG+C  K  + G+ C C   ++G  CQ +I      PC N G+C       GY+C C    YTG TCE   + C  +PC NG +C  S  Y  ++C CP G+ G TC      C  +PC++GA+C    T  GY C C  GYSG  C      C   PC NGG+C  D  N  F C+C PG+ G  C +    C  +PC+NG +C   +  D YTCTC  G+ G++C     +C    C NGG+C  DG  + FTC C  G+ G +C    + C S PC +GG+CQ     DG   Y C+C  G+ G  C+ L     S+PC+NGG C+Q      C C +G+TG  C+V
Sbjct:  639 EINLDDCASSPCDSGTCLDKID----GYECACEPGYTGSMCNINIDECAGNPCHNGGTC--EDGINGFTCRCPEGYHDPTCLSEVNECNS----NPCVHGA-CRDS---LNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTC--KDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCI--DDVAGYKCNCLL-PYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQ--NTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSC-TDGINTAF-CDCLPGFRGTFCEEDINECASDPCRNGANCT--DCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCV-DG-INSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQ-----DGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDV 1096          

HSP 2 Score: 209.92 bits (533), Expect = 1.945e-57
Identity = 182/496 (36.69%), Postives = 244/496 (49.19%), Query Frame = 2

Query:   35 INL-ACNINPCQSGGICSPSSLVAAGYTCTCPTGFSGQTCTES--SCSGNPCATGSTCVPDASANGFSCTCTAGQSNPLCNVADGCGTVSGENPCLNGGDCSLSNTLYAGYSCQCNGGFSGPMCK--ISACSKNPCQNGGSCTAKPSSPGFECACVAPYTGAICQESICS-LQQPCKNGGSCAVASGTPGYQCTCANNGYTGPTCEAS--ACDVNPCANGAQCNPSAAYPGYTCTCPVGFSGPTCSASA--CDANPCKNGATCTPDGTALGYSCACVGGYSGSTCTAS--ACDALPCFNGGTCI--VDSSNDGFTCNCQPGYSGATCSQSA--CGPNPCQNGGSCQPDNSADGYTCTCEEGYFGVNCM--ASNCDMQPCQNGGSCEPDGSADGFTCTCEVGYFGVHC--TASACTSHPCKYGGSCQPDGSDDGYTCSCLTGFFGNQCEL----------RSCVG-SNPCQNGGLCFQQGISQACICNNGFTGSNCE 1429
            IN+  C  NPC +GG C        G+TC CP G+   TC      C+ NPC  G+      S NG+ C C  G S   C++ +        NPC+NGG C     + +GY C C  GFSGP C+  I+ C+ NPC N G+C    +  G++C C+ PYTGA C+  +      PC+NGG C  +     + C C   G+ G TCE     C ++PC +GA C     + GY C C  G+SG  C      C  NPC NG +CT DG    + C C+ G+ G+ C      C + PC NG  C   VDS    +TC C  G+SG  C  +   C  + C NGG+C   +  + +TC C  G+ G  C    + CD QPC +GG+C+ DG    + CTC  GY G +C      C S PCK GG C    +   Y C C +G+ G  C++          R  V  +  CQ+GGLC   G +  C C  G+TGS CE
Sbjct:  677 INIDECAGNPCHNGGTCEDG---INGFTCRCPEGYHDPTCLSEVNECNSNPCVHGAC---RDSLNGYKCDCDPGWSGTNCDINN---NECESNPCVNGGTCK---DMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVA--GYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPT-GWQGQTCEVDINECVLSPCRHGASC--QNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCT-DGINTAF-CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDS----YTCTCPAGFSGIHCENNTPDCTESSCFNGGTCV--DGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQ-DGCG-SYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ--YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCE 1143          

HSP 3 Score: 186.422 bits (472), Expect = 1.449e-49
Identity = 173/489 (35.38%), Postives = 236/489 (48.26%), Query Frame = 2

Query:   35 INLACNINPCQSGGICSPSSLVAAGYTCTCPTGFSGQTCTESS-CSGNPCATGSTCVPDASANGFSCTCTAGQSNPLCNV-ADGCGTVSGENPCLNGGDCSLSNTLYAGYSCQCNGGFSGPMCK--ISACSKNPCQNGGSCTAKPS-SPGFECACVAPYTGAICQESICSLQ-QPCKNGGSCAVASGTPGYQCTCANNGYTGPTC--EASACDVNP--CANGAQCNPSAAYPGYTCTCPVGFSGPTCSASA--CDANPCKNGATCTPDGTALGYSCACVGGYSGSTCTA-SACDALPCFNGGTCIVDSSNDGFTCNCQPGYSGATCSQSA----CGPNPCQNGGSCQPDNSADGYTCTCEEGYFGVNCM--ASNCDMQPCQNGGSCEPDGSADGFTCTCEVGYFGVHCTA--SACTSHPCKYGGSCQPDGSDDGYTCSCLTGFFGNQCE--LRSCVGSNPCQNGGLCFQQGISQACICNNGFTGSNCEV 1432
            ++ AC  NPC++GG C   +L    Y C CP G+SG++C ++  C+ NPCA G  C+P  ++  + C C      P C    + CG   G   C +GG C   +     Y C C    +GP C+     CS +PCQNGG+C  +P+     ECAC+  +TG  C+E+I       CKNGG+C    G   Y C C    +TG  C  +   C + P  C NG  C+    + GY C C  G++G  CS +   C +  C +GATC  D  A  Y C C  G +G  C    AC + PC  G  C  +  N    C C  GY+G  CSQ       G NPC++ G C   N+   + C C +GY G  C    + C   PCQN  +C        F C C  GY GVHC      C S PC + G C    ++  + C C TGF G+ C+  +  C  S PC+NG  C     +  C+C  G+TG++CEV
Sbjct:  102 LDNACLTNPCRNGGTCDLLTLTE--YKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEAS--YICHCPPSFHGPTCRQDVNECGQKPGL--CRHGGTC---HNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTC--RPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGAC--VDGVNTYNCRCPPE-WTGQYCTEDVDECQLMPNACQNGGTCH--NTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCH-DRVASFY-CECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCI--NTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCL--DQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINE--FQCECPTGFTGHLCQYDVDEC-ASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEV 565          

HSP 4 Score: 162.925 bits (411), Expect = 6.899e-42
Identity = 184/587 (31.35%), Postives = 246/587 (41.91%), Query Frame = 2

Query:   32 QINLA-CNINPCQSGGICSPSSLVAAGYTCTCPTGFSGQTCTES--SCSGNPCATGSTCVPDASANGFSCTCTAGQSNPLCNV-ADGCGTVSGENPCLNGGDCSL-SNTLYAGYSCQCNGGFSGPMCK--ISACSKNPCQNGGSCTA------------------KPSSPG------------------FECACVAPYTGAICQESICS-LQQPCKNGGSCAVASGTPGYQCTCANNGYTGPTCE--ASACDVNPCANGAQCNPSAAYPGYTCTCPVGFSGPTCSA--------------------------------------------------SACDANPCKNGATCTPDGTALGYSCACVGGYSGSTCTAS--ACDALPCFNGGTCIVDSSNDGFTCNCQPGYSGATCSQSACGPNP----------CQNGGSCQPDNSADGYTCTCEEGYFGVNCM--ASNCDMQPCQNGGSCEPDGSADGFTCTCEVGYFGVHC--TASACTSHPCKYGGSCQ-PDGSDDGYTCSCLTGFFGNQCE--LRSCVGSNPCQNGGLCFQQGISQACICNNGFTGSNCEVQPTQP 1447
            ++ LA C  +PC++GG C  S    + ++C CPTG+ GQTC      C  +PC  G++C    +  G+ C C AG S   C    D C      NPC NGG C+   NT +    C C  GF G  C+  I+ C+ +PC+NG +CT                   + ++P                   F C C   +TG+ CQ  +     QPC +GG+C    G+  Y+CTC   GYTGP C+     CD +PC NG +C     +  Y C CP G++G  C                                                      C  +PC+NGATCT      GYSC CV GY G  C+     C + PC NGGTC+ D  N  + C+C  G  G  C  +    NP          C N G+C   +   GY+CTC  G+ G  C    + C   PC   G+       + F C C  G+ G  C    + C   PCK GG+C     +  G+ C C  GF G  CE   R+C GS  C NGG C     S  C+C   FTG  C+   + P
Sbjct:  827 EVVLAPCAPSPCRNGGECRQSEDYES-FSCVCPTGWQGQTCEVDINECVLSPCRHGASC--QNTHGGYRCHCQAGYSGRNCETDIDDCRP----NPCHNGGSCTDGINTAF----CDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGS--YRCTCPQ-GYTGPNCQNLVHWCDSSPCKNGGKC--WQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCT--DYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCL-DLPNT-YKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCV--DQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTC-GSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSP 1390          

HSP 5 Score: 162.54 bits (410), Expect = 1.070e-41
Identity = 161/483 (33.33%), Postives = 226/483 (46.79%), Query Frame = 2

Query:   62 CQSGGICSPSSLVAAGYTCTCPTGFSGQTCTESS-CSGNPCATGSTC--VPDASANGFSCTCTAGQSNPLCN--VADGCGTVSGENPCLNGGDCSLSNTLYAGYSCQCNGGFSGPMCK-ISACSKNPCQNGGSCTAKPSSPGFECACVAPYTGAICQESICSL-QQP--CKNGGSCAVASGTPGYQCTCANNGYTGPTCEA--SACDVNPCANGAQCNPSAAYPGYTCTCPVGFSGPTCSASA--CDANPCKNGATCTPDGTALGYSCACVGGYSGSTCTASA--CDALP--CFNGGTCIVDSSNDGFTCNCQPGYSGATCSQSA--CGPNPCQNGGSCQPDNSADGYTCTCEEGYFGVNCMASN-CDMQPCQNGGSCEPDGSADGFTCTCEVGYFGVHCTASA----CTSHPCKYGGSCQPDGSDDGYTCSCLTGFFGNQCEL--RSCVGSNPCQNGGLCFQQGISQACICNNGFTGSNCEV 1432
            C +GG C  ++   A   C C   F G  C + + C   PC    TC  V       ++C+C  G S PLC   + + C T    NPC NGG C L       Y C+C  G+SG  C+    C+ NPC NGG C   P    + C C   + G  C++ +    Q+P  C++GG+C    G+  Y+C C    +TGP CE     C  +PC NG  C P+     + C C  GF+G  C  +   C  N CKNG  C  DG    Y+C C   ++G  CT     C  +P  C NGGTC   +++ G+ C C  G++G  CS++   C    C +G +C   +    + C C  G  G+ C  ++ C   PC  G +C+ +       CTC  GY G  C+         ++PC++ G C    +   + C CL G+ G +CE+    CV SNPCQN   C  Q     CIC  G+ G +CEV
Sbjct:   31 CLNGGKCEAANGTEA---CVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLT----NPCRNGGTCDL--LTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCL--PFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS--YRCVCRAT-HTGPNCERPYVPCSPSPCQNGGTCRPTGDV-THECACLPGFTGQNCEENIDDCPGNNCKNGGACV-DGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTC--HNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCH--DRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCI--NTLGSFECQCLQGYTGPRCEIDVNECV-SNPCQNDATCLDQIGEFQCICMPGYEGVHCEV 489          

HSP 6 Score: 142.124 bits (357), Expect = 3.246e-35
Identity = 137/417 (32.85%), Postives = 182/417 (43.65%), Query Frame = 2

Query:   47 CNINPCQSGGICSPSSLVAAGYTCTCPTGFSGQTCTE--SSCSGNPCATGSTCVPDASANGFSCTCTAGQSNPLCNVADGCGTVSGENP-------CLNGGDC-SLSNTLYAGYSCQCNGGFSGPMCK--ISACSKNPCQNGGSCTAKPSSPGFECACVAPYTGAICQESICS-LQQPCKNGGSCAVASGTPGYQCTCANNGYTGPTCEASACDVNPCANGAQCNPS--------AAYPGYTCTCPVGFSGPTCS--ASACDANPCKNGATCTPDGTALGYSCACVGGYSGSTC--TASACDALPCFNGGTCIVDSSN-DGFTCNCQPGYSGATCSQSA--CGPNPCQNGGSCQPDNSADGYTCTCEEGYFGVNCMASNCDM----QPCQNGGSCEPDGSADGFTCTCEVGYFGVHC 1201
            C+  PC  GG C         Y CTCP G++G  C      C  +PC  G  C    +   + C C +G +   C+V      V+ +         C +GG C    NT    + C+C  G++G  C+  +  CS +PCQNG +CT      G+ C CVA Y G  C E I   L  PC+NGG+C     T  Y+C+C   G  G  CE +  D NP  +    +P             GY+CTCP GF G  C    + C +NPC    T         + C C  G++G  C    + C   PC NGGTC V S+   GF C C  G+ GATC   A  CG   C NGG+C   +     TC C   + G  C            PC N G+CEP   +  + C C   + G+ C
Sbjct: 1025 CDSQPCLHGGTCQDG---CGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCW--QTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNT----HHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLG--GYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNT--YKCSCP-RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCI--SGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLC 1425          

HSP 7 Score: 129.798 bits (325), Expect = 1.943e-31
Identity = 116/315 (36.83%), Postives = 153/315 (48.57%), Query Frame = 2

Query:  536 QPCKNGGSCAVASGTPGYQCTCANNGYTGPTCE-ASACDVNPCANGAQCN--PSAAYPGYTCTCPVGFSGPTCSA---SACDANPCKNGATCTPDGTALGYSCACVGGYSGSTC-TASACDALPCFNGGTCIVDSSNDGFTCNCQPGYSGATCSQSA--CGPNP--CQNGGSCQPDNSADGYTCTCEEGYFGVNCMASN--CDMQPCQNGGSCEPDGSADGFTCTCEVGYFGVHCTASA--CTSHPCKYGGSCQPDGSDDGYTCSCLTGFFGNQC--ELRSC-VGSNPCQNGGLCFQQGISQACICNNGFTGSNC 1426
            + C NGG C  A+GT    C C    + GP C+  + C   PC N   C+         Y C+C +GFSGP C     +AC  NPC+NG TC    T   Y C C  G+SG +C  A  C + PC NGG C+   ++  + C+C P + G TC Q    CG  P  C++GG+C   N    Y C C   + G NC      C   PCQNGG+C P G      C C  G+ G +C  +   C  + CK GG+C  DG +  Y C C   + G  C  ++  C +  N CQNGG C        C+C NG+TG +C
Sbjct:   29 ETCLNGGKCEAANGTEA--CVCG-GAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDL-LTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEAS--YICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCH--NEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVT-HECACLPGFTGQNCEENIDDCPGNNCKNGGACV-DGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDC 332