TCONS_00003449-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00003449-protein
Unique NameTCONS_00003449-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length885

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00003449-protein ID=TCONS_00003449-protein|Name=TCONS_00003449-protein|organism=Clytia hemisphaerica|type=polypeptide|length=885bp
MSLSSEQQQLQDFLNKIQLIQFYEIISNKLHITRLEHFEYATESDFTCIG
MSMPEIRRLFDSLKKNKKKFFLTKLKKSFRLSSSSNNLQDVSLQDNATQS
IQNTNIPSVPEDQKSPRQEAKCLIQEKDIRFLEVIGKGAFGSVRSAEWIT
VDNEKIFVAVKCIRRTTGNGITDIQNEVVKEASAMSCLNHPNLIRLFGVL
ISTPMMLVTELAPLGTLLKRLRQERHKFQISILSSFLVQISAGMKYLERN
KIVHRDLAARNILLVSYEKIKIGDFGLARPLDDDVEHYVMHPDGLIPFAW
CAPECLKYKRFSHASDVWAFGITAYEIFTYGAEPWAGLNGGQILEKIEEP
NNERLSCPEHCPREIYSTLYACCWNYREGERSNFQNLEKRLLETLPIEVR
ATTNSTIGTLTDGLHFIAGDIVTVFNLDSADGIWKGQNRRTGQVGFILSQ
NVDIHVGIISGAANVGQDEGVRRCSLNGLSVPAEGFVNKLWTSSQWLTET
DSTGSELRSTTPKDVSFECTNSFGSGYGGGMSSIEGGYCEDCLSQSSIDS
GCLCRCSTYSSDSSTHRCNTADLNAQTSTIGILQLTKPITIPGRARHRSR
GYNITNRGRCSSCSSSNRHSVFSDTLDRDESPSFSSNSPVCLDLVNKSMS
SLKLQDSGISTKSKLSTSEGTKSSKTLTERRRSLPDLANPRKRSLLRRSL
RFRKKKEELTSKELTVSAPIPNTESSAKFYIPGQDAMIPGGTANSSLESK
LQCNLYDLVPIRDHSKTKVLEDLAIADTRDLESRYDTPPPPKAINSNTHN
LLGNGPTNVEDSQIYENVQELKSPSPVAPPRRKKRNSIASKRYSMIELGS
DSSKYTDMSSIVNVSPNARQCIILDQKNYDILKSL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_001923XLOC_001923Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00003449TCONS_00003449Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR011511SH3_2
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR000719Prot_kinase_dom
IPR001452SH3_domain
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
GO:0005515protein binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 246..264
score: 63.19
coord: 315..337
score: 51.59
coord: 362..384
score: 23.49
coord: 296..306
score: 49.02
coord: 209..222
score: 42.46
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 130..391
e-value: 2.0E-75
score: 253.3
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 129..391
e-value: 4.5E-102
score: 355.1
IPR011511Variant SH3 domainPFAMPF07653SH3_2coord: 411..452
e-value: 9.8E-5
score: 21.9
NoneNo IPR availableGENE3D2.30.30.40coord: 408..452
e-value: 5.2E-5
score: 22.2
NoneNo IPR availableGENE3D3.30.200.20coord: 79..199
e-value: 1.5E-18
score: 66.5
NoneNo IPR availableGENE3D1.10.510.10coord: 200..407
e-value: 1.1E-43
score: 149.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 782..809
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 655..692
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 820..839
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 252..264
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 135..161
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 129..395
score: 35.354
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 410..453
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 123..395

Blast
[Close]
BLAST of TCONS_00003449-protein vs. Swiss-Prot (Human)
Match: ACK1 (Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3)

HSP 1 Score: 361.303 bits (926), Expect = 1.187e-109
Identity = 192/464 (41.38%), Postives = 279/464 (60.13%), Query Frame = 0 
Query:   10 LQDFLNKIQLIQFYEIISNKLHITRLEHFEYATESDFTCIGMSMPEIRRLFDSLKKNK----KKFFLTKLKKSFRLSSSSNNLQDVSLQDNATQSI--QNTNIPSVPEDQKSPRQEAKCLIQEKDIRFLEVIGKGAFGSVRSAEWITVDNEKIFVAVKCIRRTTGNGITDIQNEVVKEASAMSCLNHPNLIRLFGVLISTPMMLVTELAPLGTLLKRLRQERHKFQISILSSFLVQISAGMKYLERNKIVHRDLAARNILLVSYEKIKIGDFGLARPLDDDVEHYVMHPDGLIPFAWCAPECLKYKRFSHASDVWAFGITAYEIFTYGAEPWAGLNGGQILEKIEEPNNERLSCPEHCPREIYSTLYACCWNYREGERSNFQNLEKRLLETLPIEVRATTNSTIGTLTDGLHFIAGDIVTVFNLDSADGIWKGQNRRTGQVGFILSQNVDIHVGIISGAANVGQ 467
            L + L+++QL Q++  + + L++TRL HFEY    D   IGM  P  RRL++++K+ K    +K +++K+    RL        +     + +QS   + +  P  P  +  P Q   CLI EKD+R LE +G G+FG VR  EW     + + VAVKC++    +   +  ++ ++E +AM  L+H NLIRL+GV+++ PM +VTELAPLG+LL RLR+ +  F +  LS + VQ++ GM YLE  + +HRDLAARN+LL + + +KIGDFGL R L  + +HYVM     +PFAWCAPE LK + FSHASD W FG+T +E+FTYG EPW GLNG QIL KI++   ERL  PE CP++IY+ +   CW ++  +R  F  L   LLE  P ++RA  +       D LH    D++TV    + +  W+GQN RT  VG    +NV   V  +S A ++ Q
Sbjct:   10 LLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRL--------EAEFPPHHSQSTFRKTSPAPGGPAGE-GPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQ-PEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDK-EGERLPRPEDCPQDIYNVMVQ-CWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEE---PDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVG-PFPRNVVTSVAGLS-AQDISQ 456
The following BLAST results are available for this feature:
BLAST of TCONS_00003449-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACK11.187e-10941.38Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 P... [more]
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