TCONS_00003498-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00003498-protein
Unique Name	TCONS_00003498-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	658

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00003498-protein ID=TCONS_00003498-protein|Name=TCONS_00003498-protein|organism=Clytia hemisphaerica|type=polypeptide|length=658bp
METKIIYFTVSDQEEQAEFSSDALSEDIKDCFRCAAEAGPYDILKLYNHK
GNLVNISKSLPENRPNEPYKLEVVAAHCGHCGKDLHGVDVENLDTRLEKL
EKRVYVEEGYLPPEINGLKNRIEKFKTKLENVEHLSWLGLFKDMSIGPSA
LPYKSTTNNNRKCNKRTDREYKDVLESFLKMGSGLTSEETLEHLRRPTFD
NWQWEDAEMMFLVQQMFLDLGLVETFHIEVPVLQQFIFEVYKHYNLVPFH
NFRHCFCVTQMMYGMICLSEVNQRITPHEVLIMLVSAFCHDLDHPGYNNI
YQVNARTELAIRYNDISPLENHHAAVAFDILSQPRCNIFKNIKSDIYKKI
REGIIKLILATDMAKHSELVNEFKTTMEKKFDWLSPDHKESMMKMFIKAA
DVSNETRPMDVAEPWLECLLQEFFQQSDAEKLEGLPTAPFMDREKVTKSS
AQIGFIKFVLIPLYQSLSELFPAFEDFLLNPILRAFEYYVEMGRKMEEEK
QRTQEKQEKKFTPDFERKLDRDISRKLSREFDKRLHQEIHKKIVEDKERK
LSGDFRHIHPPTSGNNSRKTSFDNNRNENRNSGTTPPNSTTTLGSSPLNN
RTNIGQNSLETRSNHSKGQANNTTGVLISSFKNSGSRNNSIEEKPPVIAN
GSINHDHT

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_001944	XLOC_001944	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00003498	TCONS_00003498	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR023088	PDEase
IPR003607	HD/PDEase_dom
IPR002073	PDEase_catalytic_dom
IPR023174	PDEase_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
molecular_function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function	GO:0008081	phosphoric diester hydrolase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 115..135
None	No IPR available	COILS	Coil	Coil	coord: 489..509
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 550..658
None	No IPR available	CDD	cd00077	HDc	coord: 250..424 e-value: 1.76647E-11 score: 61.2013
None	No IPR available	SUPERFAMILY	109604	HD-domain/PDEase-like	coord: 196..512
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 317..333 score: 45.06 coord: 414..430 score: 40.71 coord: 245..258 score: 39.43 coord: 276..289 score: 33.43 coord: 290..305 score: 48.88 coord: 397..410 score: 34.71
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 247..415 e-value: 1.9E-6 score: 37.4
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	GENE3D	1.10.1300.10		coord: 171..512 e-value: 2.3E-124 score: 414.2
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 249..478 e-value: 6.2E-86 score: 287.9
IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site	PROSITE	PS00126	PDEASE_I	coord: 290..301

Blast

[Close]

BLAST of TCONS_00003498-protein vs. Swiss-Prot (Human)
Match: PDE9A (High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A OS=Homo sapiens GN=PDE9A PE=1 SV=1)

HSP 1 Score: 394.43 bits (1012), Expect = 1.404e-129
Identity = 178/322 (55.28%), Postives = 244/322 (75.78%), Query Frame = 0

Query:  185 LTSEETLEHLRRPTFDNWQWEDAEMMFLVQQMFLDLGLVETFHIEVPVLQQFIFEVYKHYNLVPFHNFRHCFCVTQMMYGMICLSEVNQRITPHEVLIMLVSAFCHDLDHPGYNNIYQVNARTELAIRYNDISPLENHHAAVAFDILSQPRCNIFKNIKSDIYKKIREGIIKLILATDMAKHSELVNEFKTTMEKKFDWLSPDHKESMMKMFIKAADVSNETRPMDVAEPWLECLLQEFFQQSDAEKLEGLPTAPFMDREKVTKSSAQIGFIKFVLIPLYQSLSELFPAFEDFLLNPILRAFEYYVEMGR---KMEEEKQRT 503
            L S ET+E LR+PTFD W WE  EM+  ++ M+ DLGLV  F I    L++++F V+ +Y   PFHNFRHCFCV QMMY M+ L  + ++ +  ++LI++ +A CHDLDHPGYNN YQ+NARTELA+RYNDISPLENHH AVAF IL++P CNIF NI  D +K+IR+G+I LILATDMA+H+E+++ FK  ME  FD+ + +H   +  + IK  D+SNE RPM+VAEPW++CLL+E+F QSD EK EGLP APFMDR+KVTK++AQIGFIKFVLIP+++++++LFP  E+ +L P+  + + Y E+ R    M+E +++T
Sbjct:  247 LLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKME-NFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567

The following BLAST results are available for this feature:

BLAST of TCONS_00003498-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00003498-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
PDE9A	1.404e-129	55.28	High affinity cGMP-specific 3',5'-cyclic phosphodi...	[more]

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TCONS_00003498-protein (polypeptide) - C. hemisphaerica