TCONS_00003866-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00003866-protein
Unique NameTCONS_00003866-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length961

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00003866-protein ID=TCONS_00003866-protein|Name=TCONS_00003866-protein|organism=Clytia hemisphaerica|type=polypeptide|length=961bp
HFRQKRTKLYRNMAPQFNDSVAMPTTPEHAPQQQNGVKVVNSKEQEKSES
DGCCKNFTNKINAGLENFFASVGLKVAMNPVKVILISLLVSFLCIAGITE
LEEENRGEKNWVSQSSDPIKHKEWIDDVFPLATRSSGLLLESTGQSNLLT
RDGLIKLYEVDQKVRLMHNGTDKLQWNDICYTPGGSVCIPSSVLELWSYN
LTLISSLTETDIKNTINTPGVVSPMTGRSIVMERIIGGPVQRDSTGNITG
APVLKVDYRLKKQDVFDKATGRNVDELANTWEEELEKTFQNNAPSGFNVY
TFSLWSNNEASRNASSGDLKFFVFGYIMVIIYLSIMLGSFSRIDHKIFLA
LSGIGIIGISIGIAYGLGSAFQLKYTSVHNVLPFLMLGIGVDDIFVIVQS
WYNVGGPNPDDRPIPEKVSLAMRHAGVSVLVTSVTDICAFAIGAATILPA
LRSFSIWCAIGILAIFLLTITLFTALLTLDAKRQRNRRDACLCCLKLSED
YEPFRCSESNILTDVLKKLYAPMILSVPGKVIVLTIVVGLLGAGCYGLTE
LEQNFDFIWFLPSDSRPRMFVEKDRIAFPGNGIPGNVYIGQIDYYNSKEQ
LDKMKRVLESDDYISQGTMNSWFHHYEEWLVGNYINELTPVNCTIETCKL
PNEARFYQLLNVFLTTKDGGNYRRMMVFNNDNKIRASKIGYSHKQLVGSK
EQVKAMDSITEIIKPGFMSDGGEEVLPFAFSQRYINWSTNKVIGIELIRN
LSLAGGCVLIVTLFLLSNFLASLMVVACVAFSLIEIAAFMGFWGLTIDTV
TTIILVIAIGLTVDYSVHIAHGFMASRAGDRNQRMTDALHEVGPAVIHGG
FSTFQAFALLAASKSYVFMTFFKVFFLVVGFGLFHGMVFLPVILSLIGPA
PYADHTGSMYSANRKKIADSGQKKEEGRQPHEMQKKVDDQNNEMSIVIDK
GGKQNKAYVPE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002172XLOC_002172Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00003866TCONS_00003866Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR003392Ptc/Disp
IPR000731SSD
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016021 integral component of membrane
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D1.20.1640.10coord: 262..491
e-value: 9.1E-38
score: 129.1
NoneNo IPR availableGENE3D1.20.1640.10coord: 686..900
e-value: 2.8E-32
score: 111.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 16..44
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 915..944
NoneNo IPR availableSUPERFAMILY82866Multidrug efflux transporter AcrB transmembrane domaincoord: 729..898
NoneNo IPR availableSUPERFAMILY82866Multidrug efflux transporter AcrB transmembrane domaincoord: 271..479
IPR003392Protein patched/dispatchedPFAMPF02460Patchedcoord: 139..897
e-value: 1.2E-94
score: 317.9
IPR000731Sterol-sensing domainPROSITEPS50156SSDcoord: 318..479
score: 32.733
IPR000731Sterol-sensing domainPROSITEPS50156SSDcoord: 770..896
score: 10.441

Blast
[Close]
BLAST of TCONS_00003866-protein vs. Swiss-Prot (Human)
Match: NPC1 (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 204.912 bits (520), Expect = 5.286e-54
Identity = 180/691 (26.05%), Postives = 321/691 (46.45%), Query Frame = 0 
Query:  276 ELANTWEEELEKTFQNNAPSGFNV-YTFSLWSNNEASRNASSGDLKFFVFGYIMVIIYLSIMLGSFSR-----IDHKIFLALSGIGIIGISIGIAYGLGSAFQLKYTS-VHNVLPFLMLGIGVDDIFVIVQSWYNVGGPNPDDR----PIPEKVSLAMRHAGVSVLVTSVTDICAFAIGAATILPALRSFSIWCAIGILAIFLLTITLFTALLTLDAKRQRNRRDACLCCLKLSEDYEPFRCSESNILTDVLKKLYAPMILSVPGKVIVLTIVVGLLGAGCYGLTELEQNFDFIWFLPSDSRPRMFVEKDRIAFPGNGIPGNVYIGQ-IDYYNSKEQ--------------LDKMKRVLESDDYISQG-TMNSWFHHYEEWL--------VGNYINELTPVNCTIETC-----------KLPNEARFYQLLNVFLTTK------DGGNYRRMMVFN----NDNKIRASKIGYSHKQLVGSKEQVKAM-------DSITEIIKPGFMSDGGEEVLPFAFSQRYINWSTNKVIGIELIRNLSLAGGCVLIVTLFLL-SNFLASLMVVACVAFSLIEIAAFMGFWGLTIDTVTTIILVIAIGLTVDYSVHIAHGFMASRAGDRNQRMTDALHEVGPAVIHG-GFSTFQAFALLAASKSYVFMTF-FKVFFLVVGFGLFHGMVFLPVILSLIGPA 900
            + A  WE+E     +N       + +T      +E +R + S D+   V  Y ++ +Y+S+ LG         +D K+ L ++GI I+  S+  + G+ S   L  T  V  V+PFL+L +GVD+IF++VQ++        D+R     + +++   +     S+ ++S ++  AF +GA +++PA+ +FS++  + +   FLL IT F +LL LD KRQ   R    CC++ +ED    + SES  L    K  Y+P++L    + IV+ I VG+L      L +++   D    +P DS    +  K    +   G P    + +  DY +SK Q              + ++    + D+Y   G   +SW   Y +W+        V N  ++    +     C           + P    F + L +FL+         GG+       N    +  ++ A+     H  L  S + + A+        ++TE      M   G     F +S  Y+ +     I  + I NL ++ G + +VT+ LL     +++++ A +A  L+ +   M  WG++++ V+ + LV++ G++V++  HI   F  S  G R +R  +AL  +G +V  G   + F    +LA +KS +F  F F+++  +V  G  HG++FLPV+LS IGP+
Sbjct:  578 QRAQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDS-DVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQR------DERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASES-CLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYF-KSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTET-----MGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPS 1254
The following BLAST results are available for this feature:
BLAST of TCONS_00003866-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NPC15.286e-5426.05Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE... [more]
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