TCONS_00004560-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004560-protein
Unique NameTCONS_00004560-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length843

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004560-protein ID=TCONS_00004560-protein|Name=TCONS_00004560-protein|organism=Clytia hemisphaerica|type=polypeptide|length=843bp
MDFITEQDADNQNSLMNFSSSRLNIVADSDEEDHHHQQSPGEEMENMNEN
HYTDDSLIRIERFESDKESKDFMLLLATTYINEARHGRNGYFIPEPKQLR
IYSWYNHRGYRLGLFIILLLNLSLVLFEQPAVHGFALPYWATMSMELICI
TIYCLRLAQAWKFMPLKRHWKDRKIIIVLLCILITLVDMAVFIILYQMKI
TTFNIRWSRILRPAFIVNFSESRQVRRTVRNIRRTLPEISSVLVLFLLVI
TLYALLGVKLFENRGIVNIATGKPFFTNFWDAYFDLYVLTTTANNPDIMI
PAYNRSNWYSLFFIIFTIICMYIFVSIFLAVVYKNYRTHLKNEVKTVVYR
KRRNMKSAFDQVKVKKGGKWVVTFQRWKQLIHYMKPTMSPVQVILFWRVL
DENDQGFIEFKQFLHISDLLHVKMDTISSRGHLFERTLSSFYFSKVSTFI
RDCVNHKLFVIFFDLVIIVNAFCIALNLESTDMIFIVLFNIEILLKLYTV
GPSEFASKFWNIFDTLVIEAATLVYILEAIFQVLRYSQFILDFLLILRVI
RLFKIIGNIKRFRVIINTIMEIGPAILTYGGIMFVLYYVYAIIGMELFHA
RVQDYGNVDFNNLTDMQRWCGTTKLNGSEFSRLFYCEKNFNNIIKSYMVL
FDLTVVNQWHVITDGFVRVTHKAARFYFFSFHMLCVIVVLNIFVAFILEA
FMLQYSLSKGNFEAAFEKKIQEKGRASSSMQGTGQENHQNTEDCDIISNP
LATSNSLQRLDLNFSINEYMTQSGMKFRLRKTRTKKAELLLQQMFEDELD
EKDLGPDLLDDENELDDVIERQNEEEADVRSPRKLTLNTIALI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002563XLOC_002563Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004560TCONS_00004560Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR005821Ion_trans_dom
IPR011992EF-hand-dom_pair
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
Vocabulary: Biological Process
TermDefinition
GO:0055085transmembrane transport
GO:0006811ion transport
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
biological_process GO:0055085 transmembrane transport
cellular_component GO:0016020 membrane
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D1.10.287.70coord: 455..706
e-value: 5.4E-23
score: 81.0
coord: 106..336
e-value: 1.6E-16
score: 59.9
NoneNo IPR availableGENE3D1.10.238.10coord: 337..418
e-value: 3.2E-4
score: 20.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 29..48
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 677..702
coord: 456..601
NoneNo IPR availableSUPERFAMILY81324Voltage-gated potassium channelscoord: 109..337
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 115..336
e-value: 2.8E-16
score: 59.4
coord: 456..706
e-value: 6.0E-29
score: 100.9
IPR011992EF-hand domain pairSUPERFAMILY47473EF-handcoord: 347..416

Blast
BLAST of TCONS_00004560-protein vs. Swiss-Prot (Human)
Match: TPC1 (Two pore calcium channel protein 1 OS=Homo sapiens GN=TPCN1 PE=1 SV=3)

HSP 1 Score: 244.202 bits (622), Expect = 5.082e-69
Identity = 183/690 (26.52%), Postives = 355/690 (51.45%), Query Frame = 0
Query:  128 EQPAVHGFALPYWATMSMELICITIYCLRLAQAWKFMPLKRHWKDRKIIIVLLCILITLVDMAVFIILYQMKITTFNIRWSRILRPAFIVNFSESRQVRRTVRNIRRTLPEISSVLVLFLLVITLYALLGVKLFENRGIVNIATGKPFFTNFWDAYFDLYVLTTTANNPDIMIPAYNRSNWYSLFFIIFTIICMYIFVSIFLAVVYKNYRTHLKNEVKTVVYRKRRNMKSAFDQVKVKKGGKWVVTFQRWKQLIHYMKPTMSPVQVILFWRVLDENDQGFIEFKQFLHISDLLHVKMDTISSRGHLFERTLSS--FYFSKVSTFIRDCVNHKLFVIFFDLVIIVNAFCIAL-------------NLESTDMIFIVLFNIEILLKLYTVGPSEFASKFWNIFDTLVIEAATLVYILEAIFQVLRYSQFILDFLLILRVIRLFKIIGNIKRFRVIINTIMEIGPAILTYGGIMFVLYYVYAIIGMELFHARVQDYGN-VDFNNLTDMQRWCGTTKLNGSEFSRLFYCEKNFNNIIKSYMVLFDLTVVNQWHVITDGFVRVTHKAARFYFFSFHMLCVIVVLNIFVAFILEAFMLQYSLSKGNFEAAFEKKIQEKGRASSSMQGTGQENHQNTEDCDIISNPLATSNSLQRLDLNFSINEYMTQSGMKFRLRKTRTKKAELLLQQMFEDELDE 801
            E PAV    L  +   ++EL  + +    L    +++ L    + ++ ++    +++  V+ A+ +++ QM     ++R +R LR  F+V+      VRR +R I ++LP    +L+L L  + ++A+LG  LF            P+F+   ++   L+VL TTAN PD+M+P+Y+R+ W  +FFI++  I +Y  +++ LAVV+  +    K + K+++  KR  ++ A+ ++ + +     +++++++ L+ + KP MS  +  L ++ L++N+   +  K F  I ++  +K     +R H F+    +    F  ++  ++     K F  F  LV+ VN   I +             ++  + ++F+ ++ +E+ LK+  +GP E+ S  WN+FD  V    T+   L  +   L    F   F+++LR ++L ++    +R+R +++T+ E+ P + + G  + + YY +AI+GME F   V  + N  + + + D  RW   T  N +     +Y   NF+NI+ S++ LF+LTVVN W++I +G    T   +R YF +F+++  +VV+ I VAFILEAF+ + + S+ N ++  +  I  +   S           +     ++       S+ + RL    S  E   Q  M F  R++RT K++L L +M+++E+ E
Sbjct:  126 EAPAVPALRLGIYVHATLELFALMVVVFELCMKLRWLGLHTFIRHKRTMVKTSVLVVQFVE-AIVVLVRQMS----HVRVTRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLLFFMIIFAILGFYLFSPN------PSDPYFSTLENSIVSLFVLLTTANFPDVMMPSYSRNPWSCVFFIVYLSIELYFIMNLLLAVVFDTFNDIEKRKFKSLLLHKRTAIQHAY-RLLISQRRPAGISYRQFEGLMRFYKPRMSARERYLTFKALNQNNTPLLSLKDFYDIYEVAALKWKAKKNREHWFDELPRTALLIFKGINILVKS----KAFQYFMYLVVAVNGVWILVETFMLKGGNFFSKHVPWSYLVFLTIYGVELFLKVAGLGPVEYLSSGWNLFDFSV----TVFAFLGLLALALNMEPFY--FIVVLRPLQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIV--FPNCCNTSTVADAYRWRNHTVGNRTVVEEGYYYLNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQTSHWSRLYFMTFYIV-TMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEIS---------KEELVAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRT-KSDLSL-KMYQEEIQE 779          
The following BLAST results are available for this feature:
BLAST of TCONS_00004560-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TPC15.082e-6926.52Two pore calcium channel protein 1 OS=Homo sapiens... [more]
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