TCONS_00049933-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049933-protein
Unique NameTCONS_00049933-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length370

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049933-protein ID=TCONS_00049933-protein|Name=TCONS_00049933-protein|organism=Clytia hemisphaerica|type=polypeptide|length=370bp
MDETPPVFPTKKPEKPVEEMLSTIDIPFDNDKFQLEEIRPESPGADATDA
PASSQTDGPFTSTFFKPAQPIQQLVQHRSERKNREGITIKHTTYHPKPLE
KNSKMSDHASNIYSDSFYKMDCFPRGKLTLINVKHFTRASGMGDYPREGT
NRDAEGLTDLFLDLGFVVDRFDNPSKKEILAIVKAAANEDYSKQACCACA
ILSHGEEGIIYGNDDFVKIRDITKMFRTRGLAGKPKFFLFQACQGSEYMN
PYDAVDGKPGQRLSEEEMALTLPSEADFLYAYSTVPGYYSWRNSRRGSWF
MEALVQVFRENAHRMDVMRMLVRVNDIISYRKSRTDEIKTDNKRQIASLI
TQMRKDFFLFPPYGPLKHAQ
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031649XLOC_031649Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049933TCONS_00049933Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR015917Pept_C14A
IPR033139Caspase_cys_AS
IPR001309Pept_C14_p20
IPR002138Pept_C14_p10
IPR029030Caspase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0004197cysteine-type endopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004197 cysteine-type endopeptidase activity
molecular_function GO:0008234 cysteine-type peptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015917Peptidase C14A, caspase catalytic domainPRINTSPR00376IL1BCENZYMEcoord: 197..205
score: 53.54
coord: 290..301
score: 58.84
coord: 228..246
score: 49.92
coord: 351..360
score: 23.33
coord: 124..137
score: 31.17
coord: 165..183
score: 21.85
IPR015917Peptidase C14A, caspase catalytic domainSMARTSM00115caspase_2coord: 117..361
e-value: 2.3E-71
score: 253.0
IPR015917Peptidase C14A, caspase catalytic domainCDDcd00032CASccoord: 117..360
e-value: 1.22397E-84
score: 258.685
NoneNo IPR availableGENE3D3.30.70.1470coord: 263..366
e-value: 4.8E-30
score: 102.9
NoneNo IPR availableGENE3D3.40.50.1460coord: 83..252
e-value: 9.6E-23
score: 80.3
NoneNo IPR availablePFAMPF00656Peptidase_C14coord: 130..358
e-value: 2.3E-37
score: 129.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 29..62
IPR033139Peptidase family C14A, cysteine active sitePROSITEPS01122CASPASE_CYScoord: 234..245
IPR001309Peptidase C14, p20 domainPROSITEPS50208CASPASE_P20coord: 124..247
score: 30.431
IPR002138Peptidase C14, caspase non-catalytic subunit p10PROSITEPS50207CASPASE_P10coord: 268..361
score: 35.72
IPR029030Caspase-like domainSUPERFAMILY52129Caspase-likecoord: 115..362

Blast
BLAST of TCONS_00049933-protein vs. Swiss-Prot (Human)
Match: CASP7 (Caspase-7 OS=Homo sapiens GN=CASP7 PE=1 SV=1)

HSP 1 Score: 186.808 bits (473), Expect = 1.355e-56
Identity = 97/246 (39.43%), Postives = 150/246 (60.98%), Query Frame = 0
Query:  118 YKMDCFPRGKLTLINVKHFTRASGMGDYPREGTNRDAEGLTDLFLDLGFVVDRFDNPSKKEILAIVKAAANEDYSKQACCACAILSHGEEGIIYGNDDFVKIRDITKMFR---TRGLAGKPKFFLFQACQGSEYMNPYDAVDGKPGQRLSEEEMALTLPSEADFLYAYSTVPGYYSWRNSRRGSWFMEALVQVFRENAHRMDVMRMLVRVNDIIS-YRKSRTDEIKTDNKRQIASLITQMRKDFFL 359
            Y M+    GK  +IN K+F + +GMG   R GT++DAE L   F  LGF V  +++ S  ++  ++K A+ ED++  AC AC +LSHGEE +IYG D    I+D+T  FR    + L  KPK F  QAC+G+E  +   A  G      ++      +P EADFL+AYSTVPGYYSWR+  RGSWF++AL  +  E+   +++M++L RVND ++ + +S++D+     K+QI  +++ + K+ + 
Sbjct:   60 YNMNFEKLGKCIIINNKNFDKVTGMG--VRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPIND--TDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 301          
The following BLAST results are available for this feature:
BLAST of TCONS_00049933-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CASP71.355e-5639.43Caspase-7 OS=Homo sapiens GN=CASP7 PE=1 SV=1[more]
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