TCONS_00049936-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049936-protein
Unique NameTCONS_00049936-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length754

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049936-protein ID=TCONS_00049936-protein|Name=TCONS_00049936-protein|organism=Clytia hemisphaerica|type=polypeptide|length=754bp
MPVFAFESAMACLSAEITANNQLFIQEDQKKAWVLNEELYDQLRRQLQEL
KVEICKQCKKNFELEKEVKFFDQRIALLINHKISVEEFPDNISYGEHRLD
TLKDDIQKQCFGNLFFLLQTEPKYIAKLTRSVDTTEIDELLQIVMFSLYG
NQYGEREEHLLLKMFELALNMEFDETDEFGSLMRQNTAISRMMTTYTRRG
PGQEYLKDTLQELVEQTNLTGLSEDLNLEVNPVKVYCALHSVVDDERNNV
TMEKALKDKDVKATINARLVKLENITKYFFDAIIQSLNSVPYGIRWLCKA
IYQLCQEKFPHVSIENITGLIGGFFLLRFINPAIVFPHNYMLLNSQPRSQ
MRRNFVLIAKLLQAISNKGASQILKEVYMKPLEAFVESRQQILQDFLMKL
CNVDDFHSNLEMEQYLSLPKDMNIRITLKEMYRLHDLLCKYQDFLTVEDN
EKLTVLLLELGDPSAKYRDQQVENVSVDINLLSRWDVSSNLKNDMINDYE
RTSERGIKALRKRCQNLLTRLLTTAPYLMQELTLKNVFAHAYKTGDDEIE
RITQLVKSHLDSLKESDPNYKEEEFYVHVKDSVSKQEIHYDKMSKELKSL
KNVQETLIWHGEFLSQQLDAYKEYLQDARNKAAVREGRASPGKMTKQNSG
PYKFSYTALEKEGVIFECKSISYKKKQNIAFTVFCKEPGIYTIQLHYKIP
LPGQQTLMELDLHLEDLLNLQHFDDPVYNINEYVVLDVRRTLSFLHKYFG
PKKL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031651XLOC_031651Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049936TCONS_00049936Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001936RasGAP_dom
IPR000593RasGAP_C
IPR008936Rho_GTPase_activation_prot
Vocabulary: Biological Process
TermDefinition
GO:0043087regulation of GTPase activity
GO:0007165signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0043087 regulation of GTPase activity
biological_process GO:0007165 signal transduction
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001936Ras GTPase-activating proteinSMARTSM00323RasGAP_2coord: 131..471
e-value: 8.5E-50
score: 181.4
IPR001936Ras GTPase-activating proteinPFAMPF00616RasGAPcoord: 165..367
e-value: 5.5E-52
score: 176.4
IPR001936Ras GTPase-activating proteinPROSITEPS50018RAS_GTPASE_ACTIV_2coord: 156..367
score: 38.861
NoneNo IPR availableGENE3D1.10.506.10coord: 161..402
e-value: 7.6E-47
score: 159.1
NoneNo IPR availableSUPERFAMILY143885RGC domain-likecoord: 650..750
IPR000593RasGAP protein, C-terminalPFAMPF03836RasGAP_Ccoord: 567..669
e-value: 2.9E-13
score: 50.0
IPR008936Rho GTPase activation proteinSUPERFAMILY48350GTPase activation domain, GAPcoord: 109..470

Blast
[Close]
BLAST of TCONS_00049936-protein vs. Swiss-Prot (Human)
Match: IQGA1 (Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens GN=IQGAP1 PE=1 SV=1)

HSP 1 Score: 189.889 bits (481), Expect = 5.796e-50
Identity = 192/783 (24.52%), Postives = 356/783 (45.47%), Query Frame = 0 
Query:   47 LQELKVEICKQCKKNFELEKEVKFFDQRIALLINHKISVEEFPDNISYG--------EHRLDTLKDDIQK--------------QCFGNLFFLLQTEPKYIAKLTRSVDTTEIDELLQIVMFSLYGNQYGEREEHLLLKMFELALNMEF-DETDEFGSLMRQNTAISRMMTTYTRRGPGQEYLKDTLQELVEQTNLTGLSED--LNLEVNPVKVYCALHSVVDDERN-------NVTMEKALKDKDVKATINARLVKLENITKYFFDAIIQSLNSVPYGIRWLCKAIYQLCQEKFPHVSIENITGLIGGFFLLRFINPAIVFPHNYMLLNSQPRSQM----RRNFVLIAKLLQ-AISNKGASQILKEVYMKPLEAFVESRQQILQDFLMKLCNVDDFHSNLEMEQY---LSLPKDMNIRITLKEMYRLHDLLCKYQDFLTVEDNEKLTVLLLEL----------GDPSAKYRDQQVENVS---VDINLLSRWDVSS--NLKNDMINDYERTSERGIKALRKRCQNLLTRLLTTAPYLMQEL----TLKNVFAHAYKTGD-----------------DEIERITQLVKSHLDSLKESDPNYKEEEFYVHVKDSVSKQEIHYDKMSKELKSLKNVQETLIWHGEFLSQQLDAYKEYLQDARNKAAVREGRAS--PGKMTKQNSGPYKFSYTA--LEKEGVIFECKSISYKKKQNIAFTVFCKEPGIYTIQLHYKIPLPGQQTLMELDLHLEDLLNLQHFDDPVYNINEYVVLDVRRTLSFLHKYF 749
            L +++ E+    + N +LE ++   D +I LL+ +KI+++   D +S+         E   D +  + QK              + + +LF+LLQT P Y+AKL   +   +  + +  V+F+LY     +REE+LLL++F+ AL  E   + D+   ++  N  + +M+ ++ R   GQ  L+  L  +V++     + +D  LN++ +PV +Y +  + ++ +         +VT E+AL  ++VK  +++ +  +  +T  F  AI+ S++ +PYG+R++ K +     EKFP    + +  +IG     R++NPAIV P  + +++     Q+    RRN   IAK+LQ A SNK    +    ++  +  ++    Q  + F    C+V +      +++Y   ++L K + I I++ E+   H LL  +QD +  E N+ +  LL +L          G+ S    D   E ++   V + L +++DV    N + D       T    +  +R +    LT +L T     QE      ++       KT D                 ++ E+I   +K  L  L   DP  K +E    +   +  Q  +  +   EL  L+     L     F  +Q+D YK Y++   +  A + G+ S  P +M  + S      YTA  L ++GV+ E + +   + +N+ F +   E  +   ++  K      +T M   LH +DLL LQ+    V  + +   ++V   +  L+K F
Sbjct:  889 LMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQ---DVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKE-----IMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMF--LGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPV-IYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKK-LTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDNLASK-GKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEE-VGDFEVKAKFMGVQMETFM---LHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKF 1654
The following BLAST results are available for this feature:
BLAST of TCONS_00049936-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
IQGA15.796e-5024.52Ras GTPase-activating-like protein IQGAP1 OS=Homo ... [more]
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