TCONS_00050025-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00050025-protein
Unique NameTCONS_00050025-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length666

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00050025-protein ID=TCONS_00050025-protein|Name=TCONS_00050025-protein|organism=Clytia hemisphaerica|type=polypeptide|length=666bp
SKVMLSGKILLYLVAVDTLSSVDGLTSRIPMKKLLNSGHNIVNTERFYLV
AFVPIRMKRFNRSGFVWREVLKYAYYEMIETFEKEGLYLNLDLLILDSEN
RLDITTSHIMDVLSKQMRDFHSPCCSAGAFNDHIIGFIGPASSSTSNHVL
NLLAFDHYPVISYSATSVRFHDKKEYPNFMRTLPSDDVQVKLILDILLRY
NWTYVAVIAQDDEYGRTGMDELKRLFSEHRICTAVERTIAIHNKTLMVKE
TKEVLKLIQNDLLANVVILWMDGVKLPTFFETAEKIKFYNKTFILSESAN
ETPSILSYDSNIIRGLLSIVPKSGQYNAFEDYFRRMMYRKDAKDDCLLRS
FFEESVGIDPTSDASINDYWGDLPMTKNGFVYDSLHAYGQAVKTFVNKHN
GTCNHTHTNVCLRSITSNRSDFIQNYLKKVAFINLHNEKVSFDSKGNVNC
TQFWISTIQPSTKHEGSLFWKRIGNWSNDQGLEMNFENFTWNNGLTIPPS
SKCGARCEPGYEHSNGSTECCWTCIPCQGNTIKQNVGHGLCMTCQPGSYT
NKQHTKCVIYLEKRFDFKSSMGIILLSFSITNLIVIISFTIVFIVYRKTP
VVLSSQLSISLAXILFDHQFDCHHIFHHRFYRLPENPRRFILATINQSSS
VFLFGTLESNSTVKYQ
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031691XLOC_031691Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00050025TCONS_00050025Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000337GPCR_3
IPR001828ANF_lig-bd_rcpt
IPR011500GPCR_3_9-Cys_dom
IPR028082Peripla_BP_I
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004930 G-protein coupled receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000337GPCR, family 3PRINTSPR00248GPCRMGRcoord: 189..205
score: 38.05
coord: 205..222
score: 33.33
coord: 137..163
score: 39.7
coord: 170..189
score: 42.5
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 90..459
e-value: 1.7E-46
score: 158.9
IPR011500GPCR, family 3, nine cysteines domainPFAMPF07562NCD3Gcoord: 499..549
e-value: 1.6E-7
score: 31.1
NoneNo IPR availableGENE3D3.40.50.2300coord: 89..449
e-value: 1.4E-41
score: 142.2
NoneNo IPR availableCDDcd06350PBP1_GPCR_family_C_likecoord: 97..335
e-value: 7.23203E-45
score: 162.54
IPR028082Periplasmic binding protein-like ISUPERFAMILY53822Periplasmic binding protein-like Icoord: 78..491

Blast
BLAST of TCONS_00050025-protein vs. Swiss-Prot (Human)
Match: GRM1 (Metabotropic glutamate receptor 1 OS=Homo sapiens GN=GRM1 PE=1 SV=3)

HSP 1 Score: 160.614 bits (405), Expect = 5.745e-41
Identity = 131/497 (26.36%), Postives = 231/497 (46.48%), Query Frame = 0
Query:  128 GAFNDHIIGFIGPASSSTSNHVLNLLAFDHYPVISYSATSVRFHDKKEYPNFMRTLPSDDVQVKLILDILLRYNWTYVAVIAQDDEYGRTGMDELKRLFSEHRICTAVERTIAIHNKTLMVKETKEVLKLIQNDLLANVVILWMDGVKLPTFFETAEKIKFYNK-TFILSESANETPSILSYDSNIIRGLLSIVPKSGQYNAFEDYFRRMMYRKDAKD-----------DCLLRSFFEESVGIDP--TSDASIND-YWGDLPMTKNGFVYDSLHAYGQAVKTFVNKHNGTCNHTHTNVC--LRSITSNRSDFIQNYLKKVAFINLHNEKVSFDSKGNVNCTQFWISTIQPSTKHEGSLFWKRIGNWSNDQGLEMNFENFTWNNGLTIPPSSKCGARCEPGYEH--SNGSTECCWTCIPCQGNTIKQNVGHGLCMTCQPGSYTNKQHTKCVIYLEKRFDFKSSMGIILLSFSITNLIVIISFTIVFIVYRKTPVVLSS 605
            G     I G IGP SSS +  V NLL     P I+YSATS+   DK  Y  F+R +PSD +Q + +LDI+ RYNWTYV+ +  +  YG +GMD  K L ++  +C A   +  I++        + + KL +    A VV+ + +G+ +        ++    + + I S+   +   ++        G ++I  +S +  +F+DYF ++    + ++            C L     E+       T + S+ + Y  D   +K GFV ++++A    ++   N H+  C   H  +C  ++ I  ++   + ++L K +FI +  E+V FD KG+    ++ I  +Q +  +     +  +G W   +G+ +N +++      +    S C   C  G       G   CCW C  C+ N   Q+     C  C  G + N   T C     +  ++ +   II ++FS   ++V +  T++F++YR TPVV SS
Sbjct:  150 GRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIA--HSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRICTGNESLEENYVQD---SKMGFVINAIYAMAHGLQ---NMHHALC-PGHVGLCDAMKPIDGSK---LLDFLIKSSFIGVSGEEVWFDEKGDAP-GRYDIMNLQYTEANRYD--YVHVGTW--HEGV-LNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQD--EFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSS 626          
The following BLAST results are available for this feature:
BLAST of TCONS_00050025-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GRM15.745e-4126.36Metabotropic glutamate receptor 1 OS=Homo sapiens ... [more]
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