TCONS_00052343-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00052343-protein
Unique Name	TCONS_00052343-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	841

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00052343-protein ID=TCONS_00052343-protein|Name=TCONS_00052343-protein|organism=Clytia hemisphaerica|type=polypeptide|length=841bp
MSCPSCQVAGRRLPSLPLAYITKSQNRMLCKGVDPTGSEMVCKDSMVQQS
SRLKTPSTEINIQEEVMKYLEAHPEKIEEYIEKKATREQLERWLIRKAKS
QQRTRDSSAQLGKLRTFSNWKFCVHKDKRKLLEKLTSEINKNKNRSYIIN
ELAESISHAIKANRFNLYLMDQTRMNLMCYTDSSPETWAHQSLATSKTIA
AHVGRENILVYVTEILGDDRFPEGTGRDGLDKSVICYPLSSSHGELYGVV
EFIREVTSPTFCEEDLEIACSYLTWGSIAVHYADISIKLEMHSGVLDFVN
KCARSIPSISTNCHELLKSVTVFCKERTKSDHFILYLSNDEGSELTSELT
DFFILNPSTNENTGKQRSFKQAITEGIPGYVTKTKKLWNVRDAYTDPYFS
RVIDKDLGYTTKTILAAPILLNDRCLGVLQFFNKSQGVYNKQDEEMVNLC
TSFYSLAIHYVQRNESQRRSENEIAVLKELYCHHTKPRRKELKDVYNSAV
LVEIPDDFYKFSFDFYQSANQASKLSFILAKDILEKCQVPYCEKVLVRFL
ATAKKHYRDMPYHNWCHAFSVAHFAYMILQGCYQNFSRAEVLALFFGSLC
HDLDHRGRNNAFYILTDHPISRLYETSTLENHHSYITTQIFAQQECDVFS
SLDKDERQEVMNVINHVIIATDLMEYFKNRNILGPIVESGTYDWSNKEHR
KLACALIMTNSDLCGSCKPYEISKISAIKVFEEFYSQGDEELKLGFTPIP
MFTRKDEMALNQAGFLNAVVMPCVKILKKIIPTLNEVEEDLKTLLDQWED
YAKEEVEQEISAEDIQQLRIPGSKVQENSLSFVRYNKSNLS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_033094	XLOC_033094	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00052343	TCONS_00052343	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR023088	PDEase
IPR003607	HD/PDEase_dom
IPR003018	GAF
IPR029016	GAF_dom-like
IPR002073	PDEase_catalytic_dom
IPR023174	PDEase_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0005515	protein binding
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
molecular_function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function	GO:0008081	phosphoric diester hydrolase activity
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 125..145
None	No IPR available	COILS	Coil	Coil	coord: 784..804
None	No IPR available	CDD	cd00077	HDc	coord: 562..735 e-value: 8.47831E-11 score: 59.6605
None	No IPR available	SUPERFAMILY	109604	HD-domain/PDEase-like	coord: 505..811
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 601..616 score: 52.88 coord: 587..600 score: 31.57 coord: 558..571 score: 54.57 coord: 627..643 score: 33.06 coord: 725..741 score: 43.29 coord: 708..721 score: 34.57
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 560..661 e-value: 2.3E-5 score: 33.8
IPR003018	GAF domain	SMART	SM00065	gaf_1	coord: 144..290 e-value: 0.0052 score: 21.9 coord: 312..468 e-value: 3.7E-9 score: 46.4
IPR003018	GAF domain	PFAM	PF01590	GAF	coord: 314..457 e-value: 3.6E-8 score: 34.0
IPR029016	GAF domain-like	GENE3D	3.30.450.40		coord: 124..285 e-value: 7.2E-14 score: 51.4
IPR029016	GAF domain-like	GENE3D	3.30.450.40		coord: 298..480 e-value: 4.2E-21 score: 75.0
IPR029016	GAF domain-like	SUPERFAMILY	55781	GAF domain-like	coord: 127..285
IPR029016	GAF domain-like	SUPERFAMILY	55781	GAF domain-like	coord: 296..482
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 562..789 e-value: 3.8E-62 score: 210.0
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	GENE3D	1.10.1300.10		coord: 497..839 e-value: 1.1E-81 score: 274.1
IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site	PROSITE	PS00126	PDEASE_I	coord: 601..612

Blast

[Close]

BLAST of TCONS_00052343-protein vs. Swiss-Prot (Human)
Match: PDE10 (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens GN=PDE10A PE=1 SV=1)

HSP 1 Score: 391.734 bits (1005), Expect = 5.691e-124
Identity = 243/773 (31.44%), Postives = 392/773 (50.71%), Query Frame = 0

Query:   64 EEVMKYLEAHPEKIEEYIEKKATREQLERWLIRKAKSQQRTRDSSA--QLGKLRTFSNWKFCVHKDKRKLLEKLTSEINKNKNRSYIINELAESISHAIKANRFNLYLMDQTRMNLMCYT-----DSSPETWAHQSLATSKTIAAHVGRENILVYVTEILGDDRFPEGTGRDGLDK--SVICYPLSSSHGELYGVVEFIREVTSPTFCEEDLEIACSYLTWGSIAVHYADISIKLEMHSGVLDFVNKCARSIPSISTNCHELLKSVTVFCKERTKSDHFILYLSNDEGSELTSELTDFFILNPSTNENTGK-----QRSFKQAITEGIPGYVTKTKKLWNVRDAYTDPYFSRVIDKDLGYTTKTILAAPILLNDRCLGVLQFFNKSQG-VYNKQDEEMVNLCTSFYSLAIHYVQRNESQRRSENEIAVLKELYCHHTKPRRKELKDVYNSAVLVEIPDDFYKFSFDFYQSANQASKLSFILAKDILEKCQVPYCE-KVLVRFLATAKKHYRDMPYHNWCHAFSVAHFAYMILQGCYQNFSRAEVLALFFGSLCHDLDHRGRNNAFYILTDHPISRLYETSTLENHHSYITTQIFAQQECDVFSSLDKDERQEVMNVINHVIIATDLMEYFKNRNILGPIVESGTYDWSNKEHRKLACALIMTNSDLCGSCKPYEISKISAIKVFEEFYSQGDEELKLGFTPIPMFTR--KDEMALNQAGFLNAVVMPCVKILKKIIPTLNEVEEDLKTLLDQWEDYAK-EEVEQEISAEDIQQ 817
            E+V  YL  HP+ ++E++ +  + E +E+WL RK     ++ D SA  ++ + +  +N +  V++    + ++L    +   +   ++ EL+  I  A KA+ F LY + +   +L  +T     +  P       +    T++A+V +    + V +ILGD+RFP GTG +   +  SV+C P+ ++ G+L G++E  R      FC    E+A + L W S+A+H   +   L   + + DF+   +++          LL+ + ++ K    +D   L+  + +  EL S+L D         E  GK      +  + +I +GI G V +T ++ N+ DAY DP F+R +D   GYTT+ IL  PI+     +GV+Q  NK  G  ++K DE    +   F +LA+H        R SE    V  E   +H+    +E + +    + V +  +   F FD     N       I    +   C     E + L RF+ + KK+YR +PYHNW HA +VAH  Y ILQ  +  F+  E   L    LCHDLDHRG +N++    DHP++ LY TST+E HH   T  I   +  ++FS+L   E ++V+ +I   IIATDL  YF NR  L  + ++G+ + +N+ HR     L+MT  DLC   K + ++K++A  ++ EF+++GDE  KLG  PIPM  R  KDE+   Q GF NAV +PC   L +I+P    + +  +  L QWE   + EE    IS+  + Q
Sbjct:   17 EKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRK---NNKSEDESAPKEVSRYQD-TNMQGVVYELNSYIEQRL----DTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTVSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDI------GEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPG---IFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQ 772

The following BLAST results are available for this feature:

BLAST of TCONS_00052343-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00052343-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
PDE10	5.691e-124	31.44	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphod...	[more]

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TCONS_00052343-protein (polypeptide) - C. hemisphaerica