TCONS_00054849-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00054849-protein
Unique NameTCONS_00054849-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1318

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00054849-protein ID=TCONS_00054849-protein|Name=TCONS_00054849-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1318bp
MMNLSNKLSTLLLCLALITPSFSVTPNGEAFKFTAKAWTRQFFKPRAYSH
PGDSFIFDCSTNDPEATVTLQRAELRGGSLYKDALTDFGNRITVMPGKQK
FSLGNVIEEDYANYRCKAVDQSNKEILLTLGRLIVNKVPRTIEPEIIPQE
AVYKIETNGNDKISCKAQGAIGVSESYLNWYREDSSGQRTLLSGDRVERK
EETTTTAYIDVEVLLFKNFQKADIGKYVCVRKVLNNPATEKSITIELEEN
VSPKITLPNNPNGIQIANIGDQIFLSCDVTGSPKPKKYWRRNGVNIHDCP
NTQEPRCTYTIRKTSFPENNGIYECVGENIVMKNAKELRVEVQVPPKLKK
PTTTIVANTKEDRELLCELSEGNPLPTFKWEQQAHSCTTDDCDPLDDQWK
PVSQQYPPASTTTKESSTIATATTATFFYRCSITNNAGSDQHVITVYRKE
EAVPQFFIESNANVINRDDELSVKCVADLYIYKDITIKRNGDEIQGLQAL
EANQTRVKSLSKKAALADNGDYTCVGSLKRGGQKTKELKIKINEITKPVI
VSLKDITVSQDAKNNQILTCQVTGNPRPEIKWSKGNKALTSLDIADESSC
DRLVSGIYRMTSQPNALVICSLDYQQHAGSYECTASNKLGSVKQTMKLTI
TAKPRIVNWFNETVIGVIEDEKENPALTCTAEGYPTPKVIWRRNSSSVLA
EGSGEAVYQIVNIDAETAGKYECFAENTMGSDLKIKSVLVLGQSPAAATN
FIENKTTLTGIIVAFVAVLIIIFILVLLYKRHLKKQYALFLEPNKNFVID
PNKTLFDQSSELPYDMVWEFPRERVTLGENLGSGAFGVVKMAEAEGIAGF
RPRDNSAQAKKRRKAIQKSRRYHQIKDKKEINGGYKQSNIDTVAVKTLKD
ETSESEYKDLASELKILIHLGEHKNIVNLLGACTTGNAKLLVILEYCSNG
NLLSYLRERREIFQPQWSPRSKDVSVTFTYTDLVHIACQISDGMEFLQAK
KCVHRDLAARNILVDENHNMKIADFGLARDIYKDEFYLKNTTGLLPIKWM
APESLFDRVFTTSSDVWSFGILLWETFTLGGSPYPGLPTDDLYGYLENGG
RMKRPDICPKDVYSVMMECWEKSPYRRPMFSQISTKLNYILTNHVPNGSY
MDMTQAQNALSTTPDEETEEDQPQDTTTKPLLEDTDDHNSDNKSTSNTNE
DKKSSLSRADSFNSTEYLEAMSNGKTPQKYGKVASDGEDDDDYVDPLNST
SIFNSPKGETYVPPPDDSEYENSNIGSPKTPLLSTNDYGDDNEYIPMTPA
DHYQNPTSFSYNGLEAVV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_034548XLOC_034548Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00054849TCONS_00054849Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR003599Ig_sub
IPR020635Tyr_kinase_cat_dom
IPR003598Ig_sub2
IPR013783Ig-like_fold
IPR013098Ig_I-set
IPR001824Tyr_kinase_rcpt_3_CS
IPR008266Tyr_kinase_AS
IPR007110Ig-like_dom
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
molecular_function GO:0004714 transmembrane receptor protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 1064..1086
score: 68.85
coord: 996..1014
score: 61.69
coord: 1108..1130
score: 43.3
coord: 1045..1055
score: 66.7
coord: 944..957
score: 47.77
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 826..1137
e-value: 2.2E-90
score: 302.3
IPR003599Immunoglobulin subtypeSMARTSM00409IG_3ccoord: 460..543
e-value: 40.0
score: 6.3
coord: 150..248
e-value: 4.4
score: 14.5
coord: 664..741
e-value: 5.1
score: 14.0
coord: 262..343
e-value: 0.004
score: 26.4
coord: 44..131
e-value: 0.45
score: 19.6
coord: 553..651
e-value: 0.034
score: 23.3
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 825..1137
e-value: 9.4E-130
score: 447.0
IPR003598Immunoglobulin subtype 2SMARTSM00408igc2_5coord: 466..531
e-value: 0.6
score: 9.2
coord: 50..123
e-value: 9.4E-4
score: 28.5
coord: 670..730
e-value: 2.2E-6
score: 37.2
coord: 561..640
e-value: 2.4E-5
score: 33.8
coord: 268..332
e-value: 2.1E-4
score: 30.7
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 343..447
e-value: 5.9E-8
score: 32.3
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 450..516
e-value: 0.028
score: 14.1
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 44..155
e-value: 1.1E-5
score: 24.7
coord: 601..690
e-value: 5.9E-13
score: 48.4
coord: 517..598
e-value: 3.2E-9
score: 36.3
coord: 691..764
e-value: 3.9E-7
score: 29.5
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 261..342
e-value: 3.1E-13
score: 49.1
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 156..260
e-value: 7.3E-6
score: 25.2
NoneNo IPR availableGENE3D3.30.200.20coord: 807..946
e-value: 2.1E-20
score: 72.1
NoneNo IPR availableGENE3D1.10.510.10coord: 947..1227
e-value: 2.2E-48
score: 164.2
NoneNo IPR availablePFAMPF13927Ig_3coord: 653..727
e-value: 6.6E-11
score: 42.6
coord: 253..329
e-value: 3.7E-9
score: 37.0
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 438..850
e-value: 4.7E-34
score: 115.6
coord: 34..451
e-value: 5.6E-15
score: 52.5
coord: 882..972
e-value: 2.9E-27
score: 93.1
coord: 965..1214
e-value: 3.1E-79
score: 265.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1157..1302
NoneNo IPR availableCDDcd00096Igcoord: 567..647
e-value: 2.03317E-9
score: 55.1879
IPR013098Immunoglobulin I-setPFAMPF07679I-setcoord: 553..650
e-value: 1.3E-11
score: 44.3
IPR001824Tyrosine-protein kinase, receptor class III, conserved sitePROSITEPS00240RECEPTOR_TYR_KIN_IIIcoord: 921..934
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 1002..1014
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 253..343
score: 10.117
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 346..445
score: 7.685
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 20..127
score: 6.687
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 548..649
score: 11.569
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 654..739
score: 10.88
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 144..244
score: 10.263
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 667..741
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 570..650
coord: 249..325
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 342..451
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 144..236
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 825..1140
score: 41.644
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 887..1134
coord: 802..849

Blast
[Close]
BLAST of TCONS_00054849-protein vs. Swiss-Prot (Human)
Match: FGFR3 (Fibroblast growth factor receptor 3 OS=Homo sapiens GN=FGFR3 PE=1 SV=1)

HSP 1 Score: 339.732 bits (870), Expect = 1.499e-100
Identity = 224/639 (35.05%), Postives = 313/639 (48.98%), Query Frame = 0 
Query:  562 AKNNQILTCQVTGNPRPEIKWSKGNKALTSLDIADESSCDRLVSGIYRMTSQPNALVICSLDYQQHAGSYECTASNKLGSVKQTMKLTIT----AKPRIVNWFNETVIGVIEDEKENPALTCTAEGYPTPKVIWRR----NSSSVLAEGSGEA----------------VYQIVNIDAETAGKYECFAENTMGSDLKIKSVLVLGQSPAA--ATNFIENKTTLTGII---VAFVAVLIIIFILVLLYKRH------------------LKKQYAL----FLEPNKNFV------IDPNKTLFDQSS-ELPYDMVWEFPRERVTLGENLGSGAFGVVKMAEAEGIAGFRPRDNSAQAKKRRKAIQKSRRYHQIKDKKEINGGYKQSNIDTVAVKTLKDETSESEYKDLASELKILIHLGEHKNIVNLLGACTTGNAKLLVILEYCSNGNLLSYLRERREIFQPQWSPRSKDVSVTFTYTDLVHIACQISDGMEFLQAKKCVHRDLAARNILVDENHNMKIADFGLARDIYKDEFYLKNTTGLLPIKWMAPESLFDRVFTTSSDVWSFGILLWETFTLGGSPYPGLPTDDLYGYLENGGRMKRPDICPKDVYSVMMECWEKSPYRRPMFSQISTKLNYILT 1142
            A N     C   GNP P I W K  +         E   +  + GI ++  Q  +LV+ S+      G+Y C   NK GS++QT  L +      +P +          V+  + E     C       P + W +    N S V  +G+                   V  + N+  E AG+Y C A N++G       ++VL   PA        E  +   GI+   V F   ++++  + L   R                   LK+Q +L     +  N   V           TL + S  ELP D  WE  R R+TLG+ LG G FG V MAEA GI     +D +A+                                 TVAVK LKD+ ++ +  DL SE++++  +G+HKNI+NLLGACT G   L V++EY + GNL  +LR RR           K      T+ DLV  A Q++ GME+L ++KC+HRDLAARN+LV E++ MKIADFGLARD++  ++Y K T G LP+KWMAPE+LFDRV+T  SDVWSFG+LLWE FTLGGSPYPG+P ++L+  L+ G RM +P  C  D+Y +M ECW  +P +RP F Q+   L+ +LT
Sbjct:  168 AANTVRFRCPAAGNPTPSISWLKNGR---------EFRGEHRIGGI-KLRHQQWSLVMESV-VPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVE---FHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVL---PAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGID----KDRAAKPV-------------------------------TVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGG-PLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLT 753
The following BLAST results are available for this feature:
BLAST of TCONS_00054849-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FGFR31.499e-10035.05Fibroblast growth factor receptor 3 OS=Homo sapien... [more]
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