TCONS_00056209-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00056209-protein
Unique Name	TCONS_00056209-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	478

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00056209-protein ID=TCONS_00056209-protein|Name=TCONS_00056209-protein|organism=Clytia hemisphaerica|type=polypeptide|length=478bp
MKSQLTFFSIITLLSTTSDAINFDDAESRLHEDLTKGYNTIIRPVKHPSD
KIEVKFDLALQQIVEVNEKSESLVVSVFLRQYWTDVKLKWNVSDYGNISS
TKFKPDSIWVPDLMLYNNAEKDDNFGGSLDQLPTRVMVNHEGSVTWLAPA
IITGKCPMNIRYFPFDTQSCRFKFGSWAYHGDEIDLQAARDENTFDLGSY
SEHSEWTIKDAYLKRNVLRYGCCPEPYPDVTVELKLKRKPLFYVLNLLLP
MIFIGVLTLLAFFLPAESGERISFAVTLMLALTVFMLIVAEMIPASSESV
PMLGIFFTCVMIEMVLMVFAMCYTLNLHFKEPNSENRIGKWTRAIVYNRL
AIYLGVRKREKKFANVNGHVKANGHVNGNAGYVKDEVEDVALKENNTVRF
KESNHNHDEPDSELESTAARLMKKSIKMAEDKAREEDIEKIIKKELVACA
KTFDVLCLIMFAFMFGMILLIYLLNTDV

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_035391	XLOC_035391	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00056209	TCONS_00056209	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 107..118 score: 50.45 coord: 234..246 score: 39.26 coord: 156..170 score: 51.43 coord: 74..90 score: 37.98
IPR006201	Neurotransmitter-gated ion-channel	TIGRFAM	TIGR00860	TIGR00860	coord: 5..473 e-value: 1.4E-95 score: 318.6
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 247..472 e-value: 6.7E-32 score: 111.4
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 240..474
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 27..240 e-value: 3.8E-65 score: 219.3
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 22..243 e-value: 1.2E-71 score: 240.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 26..240
None	No IPR available	GENE3D	1.20.58.390		coord: 244..476 e-value: 2.8E-36 score: 124.0
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 156..170

Blast

[Close]

BLAST of TCONS_00056209-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 285.804 bits (730), Expect = 4.318e-91
Identity = 166/474 (35.02%), Postives = 262/474 (55.27%), Query Frame = 0

Query:   27 ESRLHEDLTKGYNTIIRPVKHPSDKIEVKFDLALQQIVEVNEKSESLVVSVFLRQYWTDVKLKWNVSDYGNISSTKFKPDSIWVPDLMLYNNAEKDDNFGGSLDQLPTRVMVNHEGSVTWLAPAIITGKCPMNIRYFPFDTQSCRFKFGSWAYHGDEIDLQAARDENTFDLGSYSEHSEWTIKDAYLKRNVLRYGCCPEPYPDVTVELKLKRKPLFYVLNLLLPMIFIGVLTLLAFFLPAESGERISFAVTLMLALTVFMLIVAEMIPASSESVPMLGIFFTCVMIEMVLMVFAMCYTLNLHFKEPNSENRIGKWTRAIVYNRLAIYLGVRK--------------REKKFANVN-GHVKANGHVNGNAGYVK----DEVEDVALKENNTVRFK-ESNHNHDE------PDSELESTAARLMKKSIKMAEDKAREEDIEKIIKKELVACAKTFDVLCLIMFAFMFGMILLIYLL 474
            + +L+++L K YN + RPV + S  + V F L+L QI++V+EK++ L  +++L+  WTD  L+WNVS+Y  + + +F    IW PD++LYN+A  D+ F  +     T V+VN  G   +L P I    C +++R+FPFD Q C+ KFGSW+Y G  +DLQ        D+  Y  + EW +     KR+   Y CC EPYPDVT  + ++R+ L+Y LNLL+P + I  L LL F LPA+SGE+IS  +T++L+LTVFML+VAE++PA+S+SVP++  +F   MI + L V      L  H  +P+   ++ KWTR I+ N  A +L +++              R    A+V    V      NGN  Y+     D V  V   ++  V  +   +  HDE         E +   A+++++ ++   ++ R +D  + +  E    A   D LCL+ F+ +F +I  I +L
Sbjct:   26 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSA--DERFDATFH---TNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEA----DISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDG-GKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEE-VRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFS-VFTIICTIGIL 487

The following BLAST results are available for this feature:

BLAST of TCONS_00056209-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00056209-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA7	4.318e-91	35.02	Neuronal acetylcholine receptor subunit alpha-7 OS...	[more]

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TCONS_00056209-protein (polypeptide) - C. hemisphaerica