TCONS_00065116-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00065116-protein
Unique NameTCONS_00065116-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length962

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00065116-protein ID=TCONS_00065116-protein|Name=TCONS_00065116-protein|organism=Clytia hemisphaerica|type=polypeptide|length=962bp
DYPYEPSLNLQRKFQPPSSSVNQNNTYEQADPAAMRDFVSAMETKKQQQN
GQVSYDSQHSSDDNYDLPPDDLYQDPETANFNQAPPPIPRHLSTTQNKDS
DSDSDIYDEPPDELYQDPESVNFHKAPIPKPPKNNNNNDNKKNNKKKGLF
NFNKKTKPTKQPSIDDMDDGAYQDPDEASFHTQPPSTSAAQQKPSYSTCQ
STDDDMDDLYQDPEEIDFNTAALLNSKNTKPQLQRCDSNYDSPLEDYDEP
PLDARCPVAPSHRNQNAADSSDDDDVYDFPDSEPPQIPNHKKSSEIPPVI
PHHKKSSGIPPAIPIHKKSTSQEPDHSENNLHSSSSDEDDSLDYNDPETF
FAKPPALTNLKNGGRLASLRRGSNALQPLEYMPASEFTSSMDDADDDLYC
DPETSLTVKPPSFYGRNSDGEEIYSDEPLYQVYNKEVINAAHRESKKKDD
EVAINHLKQLTEDLMHKGSTMRILWSELPSVRNSGFLDNISPDDRKRQEA
MFEVITSEASYLKSLDILISHFMLNRDLLPNPNHPSHEGDELPQLLDRQQ
YHFLFSGLSAIKGVSERFLKDLRKRQQSSILMDSISDILLDYASNHLTCY
VKYCSNQVFQDRTFQHLLDTSPAFVNKLSELEKDPITQGLSLQSFLTLPM
QRITRLPLLVDAICRRCTPASEEFEKTDTALKALNAVVKESNEGARQMVR
TEEMYFIQKNLIWKTKPIPLISTSRWLVKKGDLMCLHEEGRFSQFKNQLR
QIFKGKFKPIYIFLFTDIVLVTKMKGEDKYKVIDVCQRSSLRCEIMKNIP
DPEPPKMGTLATMNVNPLKYAFTLILLENANGKTVDYHFFLSTETDKTRW
MEALSPPKSNTPTVEGESIYEEWDCPQVQAIHQYVAQQPDELTLMEGDVI
SVLRKLPDGWAEGMLLRDDTRGWFPINHTDEIDSRHMRAKNLMQRYRLIT
ASKNVINEILGK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_040823XLOC_040823Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00065116TCONS_00065116Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001452SH3_domain
IPR000219DH-domain
IPR001849PH_domain
IPR011993PH_dom-like
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0005089Rho guanyl-nucleotide exchange factor activity
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0005515 protein binding
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001452SH3 domainSMARTSM00326SH3_2coord: 876..933
e-value: 4.6E-18
score: 76.0
IPR001452SH3 domainPFAMPF00018SH3_1coord: 879..925
e-value: 1.4E-12
score: 46.9
IPR001452SH3 domainPROSITEPS50002SH3coord: 878..934
score: 13.63
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 873..938
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 500..693
e-value: 3.2E-34
score: 129.7
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 501..692
e-value: 3.8E-32
score: 111.9
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 496..694
score: 28.844
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 478..711
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 727..861
e-value: 3.6E-4
score: 29.8
IPR011993PH domain-likeGENE3D2.30.29.30coord: 718..863
e-value: 2.5E-15
score: 55.9
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 702..859
NoneNo IPR availableGENE3D2.30.30.40coord: 864..901
e-value: 3.1E-9
score: 35.7
NoneNo IPR availableGENE3D1.20.900.10coord: 494..717
e-value: 1.5E-43
score: 148.3
NoneNo IPR availableGENE3D2.30.30.40coord: 902..949
e-value: 1.5E-11
score: 43.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..357
NoneNo IPR availableCDDcd00160RhoGEFcoord: 497..692
e-value: 2.70859E-27
score: 109.31
NoneNo IPR availableCDDcd01221PH_ephexincoord: 714..861
e-value: 1.31571E-37
score: 137.387
NoneNo IPR availableCDDcd11793SH3_ephexin1_likecoord: 877..931
e-value: 1.56749E-27
score: 106.266

Blast
[Close]
BLAST of TCONS_00065116-protein vs. Swiss-Prot (Human)
Match: NGEF (Ephexin-1 OS=Homo sapiens GN=NGEF PE=1 SV=2)

HSP 1 Score: 343.969 bits (881), Expect = 1.632e-105
Identity = 194/475 (40.84%), Postives = 278/475 (58.53%), Query Frame = 0 
Query:  474 LWSELPSVRNSGFLDNISPDDRKRQEAMFEVITSEASYLKSLDILISHFMLNRDLLPNPNHPSHEGDELPQLLDRQQYHFLFSGLSAIKGVSERFLKDLRKRQQSSILMDSISDILLDYASNHLTCYVKYCSNQVFQDRTFQHLLDTSPAFVNKLSELEKDPITQGLSLQSFLTLPMQRITRLPLLVDAICRRCTPASEEFEKTDTALKALNAVVKESNEGARQMVRTEEMYFIQKNLIWKTKPIPLISTSRWLVKKGDLMCLHEEGRFSQFKNQLRQIFKGKFKPIYIFLFTDIVLVTKMKGEDKYKVIDVCQRSSLRCEIMKNIPDPEPPKMGTLATMNVNPLKYAFTLILLENANGKTVDYHFFLSTETDKTRWMEALSPPKSNTPTVEGESIYEEWDCPQVQAIHQYVAQQPDELTLMEGDVISVLRKLPDGWAEGMLLRDDTRGWFPINHTDEIDSRHMRAKNLMQRYRL 948
            LW +LP +R+SG L+ + P++ K QEAMFE++TSEASY KSL++L+SHFM              E + + ++L   + H LFS +  +  VSERFL +L  R + +I++  + DI+  YA++H + Y+ Y SNQ +Q+RT++ LL    AF   +++LE DP  +GL   SFL LP QRITRL LLV  I +R    SE       A K L  VVK  NEG R+M RTE+M  IQK + +K K +P+IS SRWL+K+G+L       + S  K       K  F  IY+FLF D++++ +    DKY+V D   R  LR E +++       +  TLA +        F L LLENA+ +   Y    S++++  RWM +L+P +  T  V   S     DCPQVQ +H YVAQQPDELTL   D++++L K  DGW  G  L D  RGWFP + T+EI +  +R++NL + +R+
Sbjct:  251 LWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYKSLNLLVSHFM--------------ENERIRKILHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILKRVEERSERECTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQ------QMSGPKTSRTLRTKKLFHEIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELED-------QGQTLANV--------FILRLLENADDREATYMLKASSQSEMKRWMTSLAPNR-RTKFVSFTSRL--LDCPQVQCVHPYVAQQPDELTLELADILNILDKTDDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRV 687
The following BLAST results are available for this feature:
BLAST of TCONS_00065116-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NGEF1.632e-10540.84Ephexin-1 OS=Homo sapiens GN=NGEF PE=1 SV=2[more]
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