TCONS_00065259-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00065259-protein
Unique NameTCONS_00065259-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length726

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00065259-protein ID=TCONS_00065259-protein|Name=TCONS_00065259-protein|organism=Clytia hemisphaerica|type=polypeptide|length=726bp
MLAARRSSKQLYQAALACRYCHQLPGEWSKKASKEMKGAEPKEKLIWKTP
EGINIKPLYTKDDTTDVENETPGSFPFTRGPYATMYTYRPWTIRQYAGFS
TVEESNKFYKKNIAAGQQGLSVAFDLPTHRGYDSDNPRVPGDVGMAGVAV
DTVEDMKTLFDGIPLDKMSVSMTMNGAVLPVLAMFIVAGEEQGVPAAKLS
GTIQNDILKEFMVRNTYIYPPEPSMRIIGDIFQYTSQNMPKFNSISISGY
HIQEAGANAVQEMAYTIADGLQYCNTGLKAGMTIDQFAPRLSFFWGVGMN
FYMEIAKFRAARRLWAHYIKEKFDAQNPKSLLLRTHSQTSGWSLTEQDPY
NNIVRTTIEGMAAVFGALALPTEFSARIARNTQIILQEESGIPNVADPWG
GSYMMESLTDEVYNSAKKIIDEIEEMGGMAKAVASGIPKLEIEKSAAKRQ
ARIDSGQETIVGVNKHKLAQEEEVDVLFIENSKVLESQINKLGQIKSSRD
AAKAKAALEAITECARSGEGNLLDLAVKASRERCSVGEISDAMEEVFKRH
VASDLSLTGAYKSEFGEDSEISQVIDRVENFSQQVGRRPRLMVAKMGQDG
HDRGAKVIATGFADLGFDVDVSPLFQTPMEVAQLAVDADVHAIGASTLAA
GHKTLVPELVACLKQLGRDDILVICGGVIPPQDYQYLYDRGVSSIFGPGT
RVPQAALTLLENIEDSLGLSPDQQAS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_040918XLOC_040918Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00065259TCONS_00065259Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR016176Cbl-dep_enz_cat
IPR006098MMCoA_mutase_a_cat
IPR006159Acid_CoA_mut_C
IPR006158Cobalamin-bd
IPR006099MeMalonylCoA_mutase_a/b_cat
Vocabulary: Biological Process
TermDefinition
GO:0008152metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0031419cobalamin binding
GO:0004494methylmalonyl-CoA mutase activity
GO:0016853isomerase activity
GO:0046872metal ion binding
GO:0016866intramolecular transferase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0008152 metabolic process
molecular_function GO:0003824 catalytic activity
molecular_function GO:0031419 cobalamin binding
molecular_function GO:0016866 intramolecular transferase activity
molecular_function GO:0016853 isomerase activity
molecular_function GO:0046872 metal ion binding
molecular_function GO:0004494 methylmalonyl-CoA mutase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D3.40.50.280coord: 571..723
e-value: 3.0E-36
score: 123.8
NoneNo IPR availableCDDcd02071MM_CoA_mut_B12_BDcoord: 590..706
e-value: 2.05653E-59
score: 196.274
NoneNo IPR availableCDDcd03679MM_CoA_mutase_alpha_likecoord: 27..547
e-value: 0.0
score: 1064.28
IPR016176Cobalamin (vitamin B12)-dependent enzyme, catalyticGENE3D3.20.20.240coord: 47..550
e-value: 1.3E-233
score: 775.6
IPR016176Cobalamin (vitamin B12)-dependent enzyme, catalyticSUPERFAMILY51703Cobalamin (vitamin B12)-dependent enzymescoord: 26..550
IPR006098Methylmalonyl-CoA mutase, alpha chain, catalyticTIGRFAMTIGR00641TIGR00641coord: 47..553
e-value: 2.6E-256
score: 848.9
IPR006159Methylmalonyl-CoA mutase, C-terminalTIGRFAMTIGR00640TIGR00640coord: 587..716
e-value: 3.8E-59
score: 196.4
IPR006158Cobalamin (vitamin B12)-binding domainPFAMPF02310B12-bindingcoord: 591..701
e-value: 6.4E-11
score: 42.2
IPR006158Cobalamin (vitamin B12)-binding domainPROSITEPS51332B12_BINDINGcoord: 588..720
score: 32.783
IPR006158Cobalamin (vitamin B12)-binding domainSUPERFAMILY52242Cobalamin (vitamin B12)-binding domaincoord: 557..717
IPR006099Methylmalonyl-CoA mutase, alpha/beta chain, catalyticPFAMPF01642MM_CoA_mutasecoord: 48..547
e-value: 3.1E-224
score: 745.2
IPR006099Methylmalonyl-CoA mutase, alpha/beta chain, catalyticPROSITEPS00544METMALONYL_COA_MUTASEcoord: 377..402

Blast
[Close]
BLAST of TCONS_00065259-protein vs. Swiss-Prot (Human)
Match: MUTA (Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens GN=MUT PE=1 SV=4)

HSP 1 Score: 1080.09 bits (2792), Expect = 0.000e+0
Identity = 517/714 (72.41%), Postives = 597/714 (83.61%), Query Frame = 0 
Query:   19 RYCHQ---LPGEWSKKASKEMKGAEPKEKLIWKTPEGINIKPLYTKDDTTDVENETPGSFPFTRGPYATMYTYRPWTIRQYAGFSTVEESNKFYKKNIAAGQQGLSVAFDLPTHRGYDSDNPRVPGDVGMAGVAVDTVEDMKTLFDGIPLDKMSVSMTMNGAVLPVLAMFIVAGEEQGVPAAKLSGTIQNDILKEFMVRNTYIYPPEPSMRIIGDIFQYTSQNMPKFNSISISGYHIQEAGANAVQEMAYTIADGLQYCNTGLKAGMTIDQFAPRLSFFWGVGMNFYMEIAKFRAARRLWAHYIKEKFDAQNPKSLLLRTHSQTSGWSLTEQDPYNNIVRTTIEGMAAVFG------------ALALPTEFSARIARNTQIILQEESGIPNVADPWGGSYMMESLTDEVYNSAKKIIDEIEEMGGMAKAVASGIPKLEIEKSAAKRQARIDSGQETIVGVNKHKLAQEEEVDVLFIENSKVLESQINKLGQIKSSRDAAKAKAALEAITECARSGEGNLLDLAVKASRERCSVGEISDAMEEVFKRHVASDLSLTGAYKSEFGEDSEISQVIDRVENFSQQVGRRPRLMVAKMGQDGHDRGAKVIATGFADLGFDVDVSPLFQTPMEVAQLAVDADVHAIGASTLAAGHKTLVPELVACLKQLGRDDILVICGGVIPPQDYQYLYDRGVSSIFGPGTRVPQAALTLLENIEDSL 717
            R  HQ   L  EW+  A K++KG  P E LIW TPEGI+IKPLY+K DT D+  E PG  PFTRGPY TMYT+RPWTIRQYAGFSTVEESNKFYK NI AGQQGLSVAFDL THRGYDSDNPRV GDVGMAGVA+DTVED K LFDGIPL+KMSVSMTMNGAV+PVLA FIV GEEQGVP  KL+GTIQNDILKEFMVRNTYI+PPEPSM+II DIF+YT+++MPKFNSISISGYH+QEAGA+A+ E+AYT+ADGL+Y  TGL+AG+TID+FAPRLSFFWG+GMNFYMEIAK RA RRLWAH I++ F  +N KSLLLR H QTSGWSLTEQDPYNNIVRT IE MAAVFG            AL LPT  SARIARNTQII+QEESGIP VADPWGGSYMME LT++VY++A K+I+EIEEMGGMAKAVA GIPKL IE+ AA+RQARIDSG E IVGVNK++L +E+ V+VL I+N+ V   QI KL +IKSSRD A A+  L A+TECA SG+GN+L LAV ASR RC+VGEI+DA+++VF  H A+D  ++GAY+ EFGE  EI+  I RV  F ++ GRRPRL+VAKMGQDGHDRGAKVIATGFADLGFDVD+ PLFQTP EVAQ AVDADVHA+G STLAAGHKTLVPEL+  L  LGR DILV+CGGVIPPQDY++L++ GVS++FGPGTR+P+AA+ +L++IE  L
Sbjct:   31 RLLHQQQPLHPEWAALAKKQLKGKNP-EDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCL 743
The following BLAST results are available for this feature:
BLAST of TCONS_00065259-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MUTA0.000e+072.41Methylmalonyl-CoA mutase, mitochondrial OS=Homo sa... [more]
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