TCONS_00069409-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00069409-protein
Unique NameTCONS_00069409-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length913

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00069409-protein ID=TCONS_00069409-protein|Name=TCONS_00069409-protein|organism=Clytia hemisphaerica|type=polypeptide|length=913bp
MVKEKEASYKRSLLASITSNETVDGDTQESCKDEMLDDDCDDSRFSFNSF
CQEWVDFCLALNGFFEKLFYKLGFLLASNPTLTVIFGVIVPLFLTGGFFR
FKMLQRTEDLYIPEKSQAFEDLRRAEKFFPVRVKAEQFIVKPHNRDRIFH
QDTFRILLQIHQNITRLPNFHQVCIKNHFQHCTVLSPLEIFKYDATNFIH
IKPTLDIVFNNKSIILSNGRQAFTSFPYYFGQFQFDHQRGLISGAESIHS
VYLVKDPIDEDIYNDLDKFDRYYTQYMEKTKTELKSKGFDLMYTSALGIE
TSISESAMQEVMLIPVAFILMTIFCAITLLRFKNQVGGHFMVAFSGIICL
FLGIGSAFGLIMMFGQPYIAFAGVLPFLVLGVGIDNIFIIIHAIDRQDPE
IRGPYRVAKALSQIGASITMATMTTIVAFFVSMFTYFPAIRYFCFYAGLS
ILFCYIQVLTVFISLLSFDVRRIENKRRDVIFCFTEKLEGDVWERAKDRV
SLKLMKIYSRFLLKTPVKYTLFTLSLVMTGLGVIGAMHIDQSFDKVVLCA
PESPYVEFYNYFNRAFPIGDEVSVIVDTPLNYGDPQIQHQYSSLSQICQE
NRHVKHASMNWMSALRDWSTKTQTNITGPHFIPALHGFLKMNPFFYPDVI
FDNRGNIKASRMIMYLKDNTDSDFLKKAMLTLRSDLREKNDLPVYAISYA
FIFYEQYAVILQNTIRNIAICATAILVITLPYLVNPKVTLLVFYGFISLM
FELFGIMYVWGVSLNALSMIILVMGIGFSVDYSAHIAHAFVKSKKRTARE
RVYEALETMGSSVAMGGVSTFIGVMVKAFAVNEIFKIFFKMVFGIVILGL
VHGLIILPIHLELFCRGDVILSHHVSYRAGKETNTKKDQEKQMLNGNGLL
HHEEQNGNIDQPV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_043259XLOC_043259Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00069409TCONS_00069409Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR003392Ptc/Disp
IPR000731SSD
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016021 integral component of membrane
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D1.20.1640.10coord: 266..480
e-value: 1.5E-37
score: 128.4
NoneNo IPR availableGENE3D1.20.1640.10coord: 666..866
e-value: 5.5E-30
score: 103.7
NoneNo IPR availableSUPERFAMILY82866Multidrug efflux transporter AcrB transmembrane domaincoord: 292..468
NoneNo IPR availableSUPERFAMILY82866Multidrug efflux transporter AcrB transmembrane domaincoord: 682..865
IPR003392Protein patched/dispatchedPFAMPF02460Patchedcoord: 113..865
e-value: 1.0E-102
score: 344.6
IPR000731Sterol-sensing domainPROSITEPS50156SSDcoord: 310..468
score: 35.424

Blast
BLAST of TCONS_00069409-protein vs. Swiss-Prot (Human)
Match: NPC1 (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 222.631 bits (566), Expect = 5.976e-60
Identity = 228/974 (23.41%), Postives = 413/974 (42.40%), Query Frame = 0
Query:   60 ALNGFFEKLFYKLGFLLASNPTLTVIFGVIVPLFLTGGFFRFKMLQRTEDLYIPEKSQAFEDLRRAEKFFPVRVKAEQFIVKPHNRDRIFHQD-------------TFRILLQIH------QNITRLPNFHQVCIKNHFQHCTVLSPLEIFKYDATNFIHIKPTLDIVFNNKSIILSNGRQAFTSFPYYFGQFQFDHQRGLISGAESIHSVYLVKDPI------------------DEDI---------------YNDLDKFDRYYTQYMEKT----KTELKSKGFDLMYTSALGIETSISESAMQEVMLIPVAFILMTIFCAITLLRFKNQ----VGGHFMVAFSGIICLFLGIGSAFGLIMMFGQPY-IAFAGVLPFLVLGVGIDNIFIIIHAIDRQDPEIRGP---YRVAKALSQIGASITMATMTTIVAFFVSMFTYFPAIRYFCFYAGLSILFCYIQVLTVFISLLSFDVRRIENKRRDVIFCFTEKLEGDVWERAKDRVSLKLMK-IYSRFLLKTPVKYTLFTLSLVMTGLGVIGAMHIDQSFDKVVLCAPESPYVEFYNYFNRAFPIGDEVSVIVDTPLNYGDPQIQHQYSSLSQICQENRHVKH---------------ASMNWMSALRDWSTKTQT------NITG---------PHFI------------PALHGFLKMNPFFYPD-------------------VIFDNRGNIKASRMIMY---LKDNTD-SDFLKKAMLTLRSDLREKNDLP-----VYAISYAFIFYEQYAVILQNTIRNIAICATAILVITLPYLVNPKVTLLVFYGFISL-MFELFGIMYVWGVSLNALSMIILVMGIGFSVDYSAHIAHAFVKSKKRTARERVYEALETMGSSVAMG-GVSTFIGVMVKAFAVNEIFKIF-FKMVFGIVILGLVHGLIILPIHLELFCRGDVILSHHVSYRAGKETNTKKDQEKQMLN 895
            A  G   +LF + G     NP   + F ++     + G    ++     DL+    SQA  +    ++ F    + EQ I++    D+  +Q                +IL Q+       +NIT   +   V +++       L+PL  +  + T    I   L+   N+ S++       F  +  Y   F +      +    S++   L+ DP                   D++                YND +K  R   Q  EK         K+    + +T+   IE  ++  +  +V  + +++ +M ++ ++ L   K+     V     +  +GI+ +   +  + G+    G P  +    V+PFLVL VG+DNIFI++ A  R D  ++G     ++ + L ++  S+ +++ +  VAFF+   +  PA+  F  +AGL++   ++  +T F+SLL  D++R E  R D IFC     E     +A +    +  K  YS  LLK  ++  +  + + +    +     +D   D+ +    +S  V+++   ++    G  V  +++   +Y   + Q+        C  +  V+                A  +W+    DW  K Q+      NIT          P  +            P    F++  P F  D                   ++  +   + A+  + Y   L+ + D  D LKKA L + S++ E   +      V+  S  ++FYEQY  I+ +TI N+ +   AI ++T+  L     + ++    I++ +  +FG+M++WG+SLNA+S++ LVM  G SV++ +HI  AF  S K +  ER  EAL  MGSSV  G  ++ F G++V AFA ++IF+IF F+M   +V+LG  HGLI LP+ L       +  S + +     E   K  + +++LN
Sbjct:  330 AFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQD-----ICLAPLSPYNTNCT----ILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLY-----CVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQR--AQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQR-DERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLD-IFCCVRGAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCG-GMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDW-VKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARL-IASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSY-----IGPSVNKAKSCATEERYKGTERERLLN 1277          
The following BLAST results are available for this feature:
BLAST of TCONS_00069409-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NPC15.976e-6023.41Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE... [more]
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