TCONS_00070167-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00070167-protein
Unique Name	TCONS_00070167-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	339

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00070167-protein ID=TCONS_00070167-protein|Name=TCONS_00070167-protein|organism=Clytia hemisphaerica|type=polypeptide|length=339bp
MMKLTLTFALACLVANVLCEHHTTVSTNTCVPECQNGGTCVNGECVCGPC
MQGALCEIETCKKFTLRYEKTGECIGVNAQSNLFLTNNCDTLFTIDDDGK
IRDLEGKRCFNGPAFNFRMNFLVAVDCGNPGTAYSTTKNGALIQKATQTC
VTPFVGILLVLDRACQDVFKFDQARCDKHNPCENGAECMQEGDKYTCKCK
PGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDI
NECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQTKKECHIKCSRYARR
NFNPVCSSDGRVFRNKCDFQEYKCFKHGKVSSVACHKKW

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_043698	XLOC_043698	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00070167	TCONS_00070167	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000742	EGF-like_dom
IPR001881	EGF-like_Ca-bd_dom
IPR013032	EGF-like_CS
IPR018097	EGF_Ca-bd_CS
IPR000152	EGF-type_Asp/Asn_hydroxyl_site
IPR002350	Kazal_dom
IPR000772	Ricin_B_lectin

Vocabulary: **Molecular Function**
Term	Definition
GO:0005509	calcium ion binding
GO:0005515	protein binding

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
molecular_function	GO:0005509	calcium ion binding
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00010	EGFBLOOD	coord: 211..222 score: 56.27 coord: 223..230 score: 51.91 coord: 231..241 score: 47.27 coord: 242..248 score: 54.62
None	No IPR available	GENE3D	2.10.25.10		coord: 251..288 e-value: 9.5E-12 score: 44.1
None	No IPR available	GENE3D	2.10.25.10		coord: 27..61 e-value: 1.3E-4 score: 21.5
None	No IPR available	GENE3D	2.10.25.10		coord: 168..213 e-value: 4.3E-12 score: 45.4 coord: 214..250 e-value: 2.4E-19 score: 68.6
None	No IPR available	PRODOM	PD936484		coord: 184..339 e-value: 3.0E-4 score: 106.0
None	No IPR available	CDD	cd00054	EGF_CA	coord: 176..209 e-value: 0.00102595 score: 35.305
None	No IPR available	CDD	cd00054	EGF_CA	coord: 249..285 e-value: 2.53318E-6 score: 43.009
None	No IPR available	CDD	cd00054	EGF_CA	coord: 211..247 e-value: 5.67426E-9 score: 50.3278
None	No IPR available	SUPERFAMILY	57196	EGF/Laminin	coord: 178..215
None	No IPR available	SUPERFAMILY	57196	EGF/Laminin	coord: 211..253
None	No IPR available	SUPERFAMILY	57196	EGF/Laminin	coord: 249..287
IPR000742	EGF-like domain	SMART	SM00181	egf_5	coord: 29..57 e-value: 60.0 score: 7.1 coord: 252..285 e-value: 3.3E-4 score: 30.0 coord: 175..209 e-value: 2.0E-5 score: 34.0 coord: 214..247 e-value: 7.3E-10 score: 48.8
IPR000742	EGF-like domain	PFAM	PF00008	EGF	coord: 176..205 e-value: 1.5E-7 score: 31.5 coord: 215..244 e-value: 1.4E-10 score: 41.1
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 249..285 score: 17.937
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 172..209 score: 15.992
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 211..247 score: 26.457
IPR001881	EGF-like calcium-binding domain	SMART	SM00179	egfca_6	coord: 249..285 e-value: 5.6E-9 score: 45.8 coord: 211..247 e-value: 1.0E-13 score: 61.5 coord: 176..209 e-value: 0.27 score: 6.4
IPR013032	EGF-like, conserved site	PROSITE	PS00022	EGF_1	coord: 235..246
IPR013032	EGF-like, conserved site	PROSITE	PS01186	EGF_2	coord: 235..246
IPR013032	EGF-like, conserved site	PROSITE	PS01186	EGF_2	coord: 273..284
IPR013032	EGF-like, conserved site	PROSITE	PS01186	EGF_2	coord: 197..208
IPR013032	EGF-like, conserved site	PROSITE	PS00022	EGF_1	coord: 273..284
IPR018097	EGF-like calcium-binding, conserved site	PROSITE	PS01187	EGF_CA	coord: 249..273
IPR018097	EGF-like calcium-binding, conserved site	PROSITE	PS01187	EGF_CA	coord: 211..235
IPR000152	EGF-type aspartate/asparagine hydroxylation site	PROSITE	PS00010	ASX_HYDROXYL	coord: 226..237
IPR000152	EGF-type aspartate/asparagine hydroxylation site	PROSITE	PS00010	ASX_HYDROXYL	coord: 264..275
IPR002350	Kazal domain	PROSITE	PS51465	KAZAL_2	coord: 291..337 score: 8.226
IPR002350	Kazal domain	SUPERFAMILY	100895	Kazal-type serine protease inhibitors	coord: 285..330
IPR000772	Ricin B, lectin domain	SUPERFAMILY	50370	Ricin B-like lectins	coord: 64..151

Blast

[Close]

BLAST of TCONS_00070167-protein vs. Swiss-Prot (Human)
Match: NOTC2 (Neurogenic locus notch homolog protein 2 OS=Homo sapiens GN=NOTCH2 PE=1 SV=3)

HSP 1 Score: 121.324 bits (303), Expect = 3.468e-30
Identity = 58/106 (54.72%), Postives = 73/106 (68.87%), Query Frame = 0

Query:  181 PCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQT 286
            PC+NG  C    + YTCKC+ GF G +CE NI+EC  + C NG TC+DGINSF+C C  G+TG  C  +INEC+ HPC   GTCVD L  ++C C LGY+G+ CQT
Sbjct:  957 PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQT 1062

HSP 2 Score: 115.931 bits (289), Expect = 2.637e-28
Identity = 51/105 (48.57%), Postives = 70/105 (66.67%), Query Frame = 0

Query:  181 PCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQ 285
            PC N   C      Y C+C PGF G +CE +ID+C +NPC+NG +C+DG+N+F+C C+PG+TGD C+TD+NEC   PC   GTC D +N + C C  G+ G  C+
Sbjct:  881 PCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE 985

HSP 3 Score: 109.768 bits (273), Expect = 2.938e-26
Identity = 50/106 (47.17%), Postives = 72/106 (67.92%), Query Frame = 0

Query:  180 NPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQ 285
            NPCE+  +C+     + C+C  G+ G  CE++I+EC S+PC+N ATC+D I  FTC C+PG+ G  CE +INEC  +PC  +G CVD +N F+C+C  G++G  CQ
Sbjct:  425 NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ 530

HSP 4 Score: 108.997 bits (271), Expect = 5.505e-26
Identity = 52/105 (49.52%), Postives = 69/105 (65.71%), Query Frame = 0

Query:  180 NPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETC 284
            NPC+NG  CM   + ++C C PGF G  C+ +++EC S PCKNG TC D +NS+TCKC  G+ G  CE +INEC    C   GTCVD +N F C+C +G++G  C
Sbjct:  918 NPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFC 1022

HSP 5 Score: 107.071 bits (266), Expect = 2.654e-25
Identity = 51/108 (47.22%), Postives = 71/108 (65.74%), Query Frame = 0

Query:  180 NPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQTK 287
            +PC N   C+   + Y C C+PG  G NCEIN D+CASNPC +G  C+DGIN ++C C PG+TG  C  DI+ECA +PC K  TC++ +N F+C+C  G    +C ++
Sbjct:  614 SPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQ 720

HSP 6 Score: 105.531 bits (262), Expect = 8.625e-25
Identity = 47/106 (44.34%), Postives = 69/106 (65.09%), Query Frame = 0

Query:  180 NPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQ 285
            +PC+N A C+ +   +TC C PGFKG +CE+ I+EC SNPC N   C+D +N F C C PG+TG +C+ DI++C+  PC     C+D  N ++C C  G++G  C+
Sbjct:  463 DPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCE 568

HSP 7 Score: 103.219 bits (256), Expect = 4.262e-24
Identity = 50/115 (43.48%), Postives = 73/115 (63.48%), Query Frame = 0

Query:  178 KHNPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQTK-KECH 291
            + NPC N  +C+ + +++ C C PGF G  C+I+ID+C+S PC NGA CID  N + C+C  G+TG LCE +I+ C   PC  HG C D ++ + C+C+ GY G  C  +  EC+
Sbjct:  499 QSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECY 612

HSP 8 Score: 102.449 bits (254), Expect = 8.744e-24
Identity = 48/104 (46.15%), Postives = 66/104 (63.46%), Query Frame = 0

Query:  182 CENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQ 285
            C++   C+  G+ + C+C  G+ G  CE  +DECASNPC++GATC D I  + C+CVPGY G  CE +++EC   PC   GTC+D +N FKC C  G  G  C+
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCE 1223

HSP 9 Score: 102.449 bits (254), Expect = 9.335e-24
Identity = 53/109 (48.62%), Postives = 69/109 (63.30%), Query Frame = 0

Query:  180 NPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQTKK 288
            NPC +G  CM   ++Y+C C PGF G  C I+IDECASNPC+ GATCI+G+N F C C  G     C + +NEC  +PC  HG C   L+ +KC+CD G+ G  C+  K
Sbjct:  652 NPCIHGI-CMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPC-IHGNCTGGLSGYKCLCDAGWVGINCEVDK 758

HSP 10 Score: 100.908 bits (250), Expect = 2.604e-23
Identity = 50/107 (46.73%), Postives = 68/107 (63.55%), Query Frame = 0

Query:  180 NPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHP-CGKHGTCVDCLNEFKCVCDLGYSGETCQ 285
            NPC++GA C      Y C+C PG++G NCE  +DEC + PC+NG TCID +N F C C PG  G LCE +I++CA  P C   G C+D +  + C C  G++GE C+
Sbjct: 1156 NPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262

HSP 11 Score: 100.138 bits (248), Expect = 5.539e-23
Identity = 47/112 (41.96%), Postives = 70/112 (62.50%), Query Frame = 0

Query:  178 KHNPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNP-CKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGT--CVDCLNEFKCVCDLGYSGETCQT 286
            ++ PC+NG  C+   + + C C PG +G  CE NID+CA  P C NG  C+D I  ++C+C+PG+ G+ CE DINEC  +PC   G+  C+   N++ CVC   ++G  C+T
Sbjct: 1192 QNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCET 1303

HSP 12 Score: 96.6709 bits (239), Expect = 7.155e-22
Identity = 48/108 (44.44%), Postives = 67/108 (62.04%), Query Frame = 0

Query:  180 NPCENGAECMQEGD-KYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHP--CGKHGTCVDCLNEFKCVCDLGYSGETC 284
            +PC NG  C Q GD  + C C PGF+G  CE NID+C ++ C+NG  C+DG+N++ C+C P +TG  C  D++EC   P  C   GTC +    + CVC  G+SG+ C
Sbjct:  228 SPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDC 335

HSP 13 Score: 89.7373 bits (221), Expect = 1.474e-19
Identity = 47/107 (43.93%), Postives = 66/107 (61.68%), Query Frame = 0

Query:  180 NPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQT 286
            NPC +G  C      Y C C  G+ G NCE++ +EC SNPC+NG TC + +N + C C  G+ G  C+ +I+ECA +PC   GTC D ++ + C C L Y+G+ CQT
Sbjct:  727 NPCIHG-NCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQT 832

HSP 14 Score: 89.3521 bits (220), Expect = 2.427e-19
Identity = 58/149 (38.93%), Postives = 78/149 (52.35%), Query Frame = 0

Query:  141 ALIQKATQTCVTPFVGILLVLDRACQDVFKFDQARCDKHNPCENGAEC-MQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCIDGINSFTCKCVPGYTGDLCETDINEC--AGHPCGKHGTCVDCLNEFKCVCDLGYSGETCQT 286
            A++ KAT  C + F G         +D        C    PC NG  C M   D Y C C+ GF G  C+   D C S+PC NG+TC    N F+CKC+ G+TG  CETD+NEC   GH C   GTC++    ++C C  G++G+ C +
Sbjct:   83 AMLGKATCRCASGFTG---------EDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQW-TDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGH-CQHGGTCLNLPGSYQCQCPQGFTGQYCDS 220

HSP 15 Score: 79.7221 bits (195), Expect = 2.977e-16
Identity = 43/114 (37.72%), Postives = 60/114 (52.63%), Query Frame = 0

Query:  172 DQARCDKHNPCENGAECMQEGDKYTCKCKPGFKGCNCEINIDECASNPCKNGATCID-GINSFTCKCVPGYTGDLCETDINECAGHPCGKHGTCVDCLNEFKCVCDLGYSGETC 284
            D   CD    C++G  C+     Y C+C  GF G  C+     CA +PC NG TC   G  +F C C+PG+ G  CE +I++C  H C   G CVD +N + C C   ++G+ C
Sbjct:  182 DVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFC 295

The following BLAST results are available for this feature:

BLAST of TCONS_00070167-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00070167-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
NOTC2	3.468e-30	54.72	Neurogenic locus notch homolog protein 2 OS=Homo s...	[more]

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TCONS_00070167-protein (polypeptide) - C. hemisphaerica