TCONS_00049584-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00049584-protein
Unique NameTCONS_00049584-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length939

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00049584-protein ID=TCONS_00049584-protein|Name=TCONS_00049584-protein|organism=Clytia hemisphaerica|type=polypeptide|length=939bp
KMLRGAMSSTIPGIPWYRLTVIFLLVVSVYSFKYVKSDSKFYHTKNGEVE
YERDGKIYRIGRIDFNSVKIKGRPTATDDFKIPPNKMKNGKRHRRSASST
AESVKEKEQKRRSEYINKDGLEECLPMEYEDQPTNKAFVMNHDDKILWLG
VVIPIMETDFKINPRRGMTNFQSLRYAVELANAGMKSLLMMGGWTIRLRR
LYPSVNLGDPSLIRYGFKCRTSNVTAFYGPFYQDNYDVLAAMTHIYPITF
MSQSSSKENDDRLRYQFGKSKNQIHKYTLQTNPSTLFRNQVILDIILKFG
WNFVAVFHSSFYIGESTSDVIFLLDKSGICIPSTRLKGGIEGNTDENIKA
RIIELRENHPTLRVLLLLTDVADTRSVLKAIKELDLQNHFTLLFADRGVN
DIEVVRGYEDIAVGAITIEPVNFHEKHLEQLADFEQWMLKANPTNTRNLY
FHWYWEQTFECELNSHILDRMLTPDQRGTYQKKCTGDEQFQIGKGVYPDR
NLFRGAMDTVEAIVFTLYRMELISTQSCEWVTSNKDLINIWSKDGCDKCP
WNTTLCFNRFFEGVFPSINMLNYQRLLPDIGWSLKYNHPRDIPNASYEIS
NFIFTNGRYQSVPIGNWTIKVPAHETKVYFPTDVLKMNKPHMVIDTDRIF
WRNGSAPEGKCALDCAPGYTRLYYLSKREVRKCCWKCEKCDTHDIVVENK
CHRCDRFQTPNIIKNVCEPLPIYHITLFSNSFATVLGIASMLGIIIVIAF
GFILIYNNNKHVIKAAGRELSYCMLSGIFFLFISTILFLVYPSKSICIAR
FALPPMAQVVVYSSFLLKNIRLYRIFERYDRKVTQPYLISPKSQVIILLI
IMSFQIGFAFIWTYDGLPDVTRVLTSNEKQVMLMCTKTHKVRFVLNYFPA
IFIIAACCIYCYKIRGLPKTYNETKFYIFTAFCSFTLLR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031443XLOC_031443Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00049584TCONS_00049584Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000337GPCR_3
IPR001828ANF_lig-bd_rcpt
IPR011500GPCR_3_9-Cys_dom
IPR017978GPCR_3_C
IPR028082Peripla_BP_I
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004930 G-protein coupled receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000337GPCR, family 3PRINTSPR00248GPCRMGRcoord: 844..867
score: 22.4
coord: 899..922
score: 29.04
coord: 167..182
score: 22.85
coord: 760..782
score: 40.49
coord: 805..826
score: 31.25
coord: 288..304
score: 31.99
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 221..445
e-value: 6.7E-15
score: 55.0
IPR011500GPCR, family 3, nine cysteines domainPFAMPF07562NCD3Gcoord: 657..710
e-value: 2.4E-6
score: 27.3
IPR017978GPCR family 3, C-terminalPFAMPF000037tm_3coord: 744..936
e-value: 1.1E-31
score: 110.4
IPR017978GPCR family 3, C-terminalPROSITEPS50259G_PROTEIN_RECEP_F3_4coord: 732..939
score: 27.449
NoneNo IPR availableGENE3D3.40.50.2300coord: 284..471
e-value: 2.1E-20
score: 72.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 76..113
IPR028082Periplasmic binding protein-like ISUPERFAMILY53822Periplasmic binding protein-like Icoord: 164..618

Blast
BLAST of TCONS_00049584-protein vs. Swiss-Prot (Human)
Match: GRM8 (Metabotropic glutamate receptor 8 OS=Homo sapiens GN=GRM8 PE=2 SV=2)

HSP 1 Score: 234.572 bits (597), Expect = 1.410e-64
Identity = 193/747 (25.84%), Postives = 324/747 (43.37%), Query Frame = 0
Query:  208 GDPSLIRYGFKCRTSNVTAFYGPFYQDNYDVLAAMTHIYPITFMS-QSSSKENDDRLRYQFGKSKNQIHKYTLQTNPSTLFRNQVILDIILKFGWNFVAVFHSSFYIGESTSDVIFLLDK--SGICIP-STRLKGGIEGNTDENIKARIIELRENHPTLRVLLLLTDVADTRSVLKAIKELDLQNHFTLLFADRGVNDIEVVRGYEDIAVGAITIEPVNFHEKHLEQLADFEQWMLKANPTNTRNLYFHWYWEQTFECELNSHILDRMLTPDQRGTYQKKCTGDEQFQIGKGVYPDRNLFRGAMDTVEAIVFTLYRMELISTQSCEWVTSNKDLINIWSKDGCDKCPWNTTLCFNRFFEGVFPSINMLNYQRLLPDI---------GWSLKYNHPRDIPNASYEISNFIFTNGRYQSVPIGNWTIKVPAHETKVYFPTDVLKMNKPHMVIDTDRIFWRNGSAPEGKCALDCAPGYTRLYYLSKREVRK--CCWKCEKCDTHDIVV-ENKCHRCDRFQTPNIIKNVCEPLPIYHITLFSNSFATVLGIASMLGIIIVIAFGFILIYNNNKHVIKAAGRELSYCMLSGIFFLFISTILFLVYPSKSICIARFALPPMAQVVVYSSFLLKNIRLYRIFERYDRKVTQPYLISPKSQVIILLIIMSFQIGFAFIWTYDGLPDV------TRVLTSNEKQVMLMCTKTHKVRFVLNYFPAIFIIAACCIYCYKIRGLPKTYNETKFYIFTAF 932
            GDP +       +   ++   G        ++A +  ++ I  +S  S++ E  D  RY F            +  P   ++ Q ++DI+   GWN+V+   S    GES  +    + +   G+CI  S ++         E I  R++E     P  R +++  +  D R +L+A K+L+   HF  + +D   + I  V   E+IA GA+TI P       ++    + +    AN  N RN++F  +WE+ F C+L SH         +R ++ KKCTG E+       Y      +  +D V ++ + L+ M             +KDL           CP    LC         P ++ ++ + LL  I         G  + +N   D P   Y+I  +  TN   +   IG+WT                   N+ H+ ++  +   R  + P   C+L C PG        K+ V+   CCW CE+C+ ++  V E  C  C   Q PN+ +  C+ +PI  +   S  +A V    ++LGII         +  N+  +++A+GRELSY +L+GIF  +  T L +  P   IC  R     +     Y++ L K  R++RIFE+  + VT P  ISP SQ++I   ++S Q+   F+W     P +       R L   + + +L C     +  + +   +I ++  C +Y  K RG+P+T+NE K   FT +
Sbjct:  136 GDPPIFT-----KPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFS----------RVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET----PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILP---KRASIDGFDRYFRSRTLAN--NRRNVWFAEFWEENFGCKLGSH--------GKRNSHIKKCTGLERIARDSS-YEQEGKVQFVIDAVYSMAYALHNM-------------HKDL-----------CPGYIGLC---------PRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWT-------------------NQLHLKVEDMQWAHREHTHPASVCSLPCKPGE------RKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHS-PWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKC-DISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMY 788          
The following BLAST results are available for this feature:
BLAST of TCONS_00049584-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GRM81.410e-6425.84Metabotropic glutamate receptor 8 OS=Homo sapiens ... [more]
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