TCONS_00050053-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00050053-protein
Unique NameTCONS_00050053-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1403

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00050053-protein ID=TCONS_00050053-protein|Name=TCONS_00050053-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1403bp
MSFYILLEKLLYFWLVIELTDIDFSIDDFQFRALHKYQLECNNNTQVKLD
TESLENMSTRSGFYSVSSSSYEDEDERFLSEESKTTKSNVVEQEKSPPSK
PGHSYTRKYSKYGKNKRNKSGEECIKEGYLMKQNGSFQRWKQTYFKIYPQ
QIYYAKNPSSSLFHEINVTEISIAETSVNNVNNSFKVITGQISLSLSAET
RREMEEWVSSFKLASQREGRNLNELSETLSGDHHWYSCTHSRPTFCNVCR
DTLPGVTIKGLSCEVCRYKVHKKCAAKAPKSCKWTTLDCIPPEERLVGVG
NDEYAMPHQWLEGNITPGQKCIVCGKLCGSKRRMQDFMCLWCDTVVHGGS
CKLQFQKRCSLGLNCLSVIPATTIKRAEHLGPGVWEAIYHNRSPLIVFVN
SKSGDNQGVKFMRRFKQLLNPAQVFDLSVAGPTLGVSMCKNFKQFRILVC
GGDGSVGWVMTELDKQKLTNKCQIGVLPLGTGNDLARVFGWGSACYDVGV
IPLVLQQLERARPSMLDRWAIMCKEFPSGRPEGDDISGYEDSIVMHITRM
LASNQYEIVIQSAKFLCETIRNFVELVGVASGSEASNVASGSEASNVADL
KLTSKCEVLQDKLTLLLRTLQIESEASSFLKSLDLTRRSSTMENLDIMAT
LDGKKLKWHSDSELNTSMDSSRAKASGLGPGTDNAGFGQTKKTSKQKVFI
PKEHLWSRANSLKKAMREIIDHTEKAVDEQNQQTSEAIAQCAAAVRSSNI
STKGTHQPLSHILDDLPETIIDADEKDDTMEKGSLETESVKKDRVSATSP
DGSPQHRNISAQDESDVMSDKAISKAKQDTKPISDKPNYPEYLSAPSSPF
FNLKPDVFFAKNQKSSNTVVYPGTVIARAFQKPAVSDGFISKVLLANANA
FCATALPGNEDEQDKLNNFKEKCVMNNYFGVGIDAKISLDFHNKREEHPE
KCRSRTRNFIWYGVLGGMELINRTYRNLEQNVHLEVDGHKIHLPSLQGIV
VLNIPSYMGGSNFWGTKKEVDGFVSPSFDDRMLEVVAVLGASQMGMSKVF
GGMQHHRIAQCHTVKITITDEAVPVQVDGEAWMQPPGIVQIVHKNRAPML
MRDREFEETLRSWHERQVHKVDRMAEPVSTPEMCLIKPLAESVTSLVRSI
KAASMINSVVQQELYQAASNLSALAEKVRNQEVINRGEATEFIALSKGFI
SDVNEKLWTLKPQLSQELETRIVSSLSQADQEMSKFLDNDDNKDSKDDIS
LLQVDTHATAATTSTTNTVTPSNTKSSSLGNTGGASSSGSGRSWLMFGRK
SHSCRERAPEATTIDFLEKKAVHEWDVNEVGLWLDTIGCSEYKDNFKQHD
ITGPELIKLERHDLNDLGVKKVGHSKRILEKSKQLARYRKVPKPSKWTRK
TVS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031700XLOC_031700Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00050053TCONS_00050053Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002219PE/DAG-bd
IPR000756Diacylglycerol_kin_accessory
IPR001660SAM
IPR001849PH_domain
IPR001206Diacylglycerol_kinase_cat_dom
IPR017438ATP-NAD_kinase_dom_1
IPR011993PH_dom-like
IPR013761SAM/pointed
IPR016064NAD/diacylglycerol_kinase
Vocabulary: Biological Process
TermDefinition
GO:0035556intracellular signal transduction
GO:0007205protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008152metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0004143diacylglycerol kinase activity
GO:0005515protein binding
GO:0016301kinase activity
GO:0003951NAD+ kinase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0008152 metabolic process
biological_process GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
molecular_function GO:0004143 diacylglycerol kinase activity
molecular_function GO:0016301 kinase activity
molecular_function GO:0003951 NAD+ kinase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 712..733
NoneNo IPR availableGENE3D3.30.60.20coord: 305..360
e-value: 7.8E-14
score: 51.0
NoneNo IPR availableGENE3D3.30.60.20coord: 239..288
e-value: 3.5E-15
score: 55.1
NoneNo IPR availableGENE3D1.10.150.50coord: 1321..1392
e-value: 2.9E-21
score: 74.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1262..1292
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 77..118
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 667..695
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 774..839
NoneNo IPR availableSUPERFAMILY57889Cysteine-rich domaincoord: 300..362
NoneNo IPR availableSUPERFAMILY57889Cysteine-rich domaincoord: 226..285
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainSMARTSM00109c1_12coord: 233..282
e-value: 4.0E-15
score: 66.2
coord: 308..359
e-value: 0.012
score: 23.8
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainPFAMPF00130C1_1coord: 233..283
e-value: 2.3E-10
score: 40.1
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainPROSITEPS00479ZF_DAG_PE_1coord: 233..282
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainPROSITEPS50081ZF_DAG_PE_2coord: 232..282
score: 13.607
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainCDDcd00029C1coord: 308..360
e-value: 1.12916E-5
score: 43.6348
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domainCDDcd00029C1coord: 233..282
e-value: 9.44738E-17
score: 75.9915
IPR000756Diacylglycerol kinase, accessory domainSMARTSM00045dagk_c4b_2coord: 924..1081
e-value: 5.3E-88
score: 308.3
IPR000756Diacylglycerol kinase, accessory domainPFAMPF00609DAGK_acccoord: 924..1080
e-value: 1.6E-49
score: 168.2
IPR001660Sterile alpha motif domainSMARTSM00454SAM_4coord: 1322..1388
e-value: 2.8E-19
score: 80.1
IPR001660Sterile alpha motif domainPFAMPF00536SAM_1coord: 1324..1380
e-value: 8.8E-17
score: 61.2
IPR001660Sterile alpha motif domainPROSITEPS50105SAM_DOMAINcoord: 1325..1388
score: 18.428
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 124..218
e-value: 1.4E-16
score: 71.1
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 125..215
e-value: 1.7E-12
score: 47.7
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 123..216
score: 14.595
IPR001206Diacylglycerol kinase, catalytic domainSMARTSM00046dagk_c4a_7coord: 394..519
e-value: 1.5E-49
score: 180.6
IPR001206Diacylglycerol kinase, catalytic domainPFAMPF00781DAGK_catcoord: 394..495
e-value: 6.3E-25
score: 87.1
IPR001206Diacylglycerol kinase, catalytic domainPROSITEPS50146DAGKcoord: 390..525
score: 36.674
IPR017438Inorganic polyphosphate/ATP-NAD kinase, domain 1GENE3D3.40.50.10330coord: 388..528
e-value: 2.7E-29
score: 101.0
IPR011993PH domain-likeGENE3D2.30.29.30coord: 122..238
e-value: 1.4E-19
score: 69.5
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 121..238
IPR013761Sterile alpha motif/pointed domainSUPERFAMILY47769SAM/Pointed domaincoord: 1320..1387
IPR016064NAD kinase/diacylglycerol kinase-like domainSUPERFAMILY111331NAD kinase/diacylglycerol kinase-likecoord: 392..521
coord: 921..1099

Blast
BLAST of TCONS_00050053-protein vs. Swiss-Prot (Human)
Match: DGKD (Diacylglycerol kinase delta OS=Homo sapiens GN=DGKD PE=1 SV=4)

HSP 1 Score: 911.753 bits (2355), Expect = 0.000e+0
Identity = 552/1319 (41.85%), Postives = 730/1319 (55.34%), Query Frame = 0
Query:   98 PSKPGHSYTRKYSKYGKNKRNKSGEECIKEGYLMKQNGSFQRWKQTYFKIYPQQIYYAKNPSSSLFHEINVTEISIAETSVNNVNNSFKVITGQISLSLSAETRREMEEWVSSFKLASQREGRNLNELS-ETLSGDHHWYSCTHSRPTFCNVCRDTLPGVTIKGLSCEVCRYKVHKKCAAKAPKSCKWTTLDCIPPEERLVGVGNDEYAMPHQWLEGNITPGQKCIVCGKLCGSKRRMQDFMCLWCDTVVHGGSCKLQFQKRCSLGLNCLSVIPATTIKRAEHLGPGVWEAIY--HNRSPLIVFVNSKSGDNQGVKFMRRFKQLLNPAQVFDLSVAGPTLGVSMCKNFKQFRILVCGGDGSVGWVMTELDKQKLTNKCQIGVLPLGTGNDLARVFGWGSACYDVGVIPLVLQQLERARPSMLDRWAIMCKEFPSGR--------------PEGDDISGYEDSIVMHITRMLASNQYEIVIQSAKFLCETIRNFVELVGVASGSEASNVASGSEASNVADLKLTSKCEVLQDKLTLLLRTLQIESEASSFLKSLDLTRRSSTMENLDIMATLDGKKLKWHSDSELNTSMDSSRAKASGLGPGTDNAGFGQTKKTSKQKVFIPKEHLWSRANSLKKAMREIIDHTEKAVDEQNQQTSEAIAQCAAAVRSSNISTKGTHQPLSHILDDLPETIIDADEKDDTMEKGSLETESVKKDRVSATSPDGSPQHRNISAQDESDVMSDKAISKAKQDTKPISDKPNYPEYLSAPSSPFFNLKPDVFFAKNQKSSNTVVYPGTVIARAFQKPAVSDGFISKVLLANANAFCATALPGNEDEQDKLNNFKEKCVMNNYFGVGIDAKISLDFHNKREEHPEKCRSRTRNFIWYGVLGGMELINRTYRNLEQNVHLEVDGHKIHLPSLQGIVVLNIPSYMGGSNFWGTKKEVDGFVSPSFDDRMLEVVAVLGASQMGMSKVFGGMQHHRIAQCHTVKITIT-DEAVPVQVDGEAWMQPPGIVQIVHKNRAPMLMRDREFEETLRSWHERQVHKVDR------MAEPVSTPEMCLIKPLAESVTSLVRSIKAASMINSVVQQELYQAASNLSALAEKVRNQEVINRGEATEFI-ALSKGFISDVNEKLWTLKPQLSQELET----RIVSSLSQADQEMSKFLDNDDNKDSKDDISLLQVDTHATAATTSTTNTVTPSNTKSSSLGNTGGASSSGSGRSWLMFGRKSHSCRERAPEATTIDFLEKKAVHEWDVNEVGLWLDTIGCSEYKDNFKQHDITGPELIKLERHDLNDLGVKKVGHSKRILEKSKQLAR 1387
            P  P     RK S  G+ ++    +  IKEG L KQN SFQR K+ YFK+  + +YYAK   S +F E+++T+ S+AE+S  NVNNSF VIT    L L A+ R+EME+W+++ K    RE     + S +  SG H+WY+C+H+RPT+CNVCR+ L GVT  GLSCEVC++K HK+CA +A  +CKWTTL  I  +   +    D  AMPHQWLEGN+    KC VC K CGS  R+QD+ CLWC  +VH  SCK     +C LGL  +SVIP T +   +    G W+A       SPL+VFVNSKSGDNQGVKF+RRFKQLLNPAQVFDL   GP LG+ + + F  FRILVCGGDGSVGWV++E+D   L  +CQ+GVLPLGTGNDLARV GWGSAC D   +P +L++LERA   MLDRW++M  E    R               E   I  YEDS+  H++++L S+Q+ +VI SAK LCET+++FV  VG A           SE S V    +  KC VL++KL  LL+TL  ES+ASS L +   T                              + ++     SG   G+       +   ++ ++F P+E L  RANSLKKA+R+II+HTEKAVDEQN QT E          S          PLSH                         +ES            G P+ R  S +  S    +K ISK        +  P  P+  S    P  N K              ++YP     RA    ++  G +   LL NA+ F          E + L  + EKCVMNNYFG+G+DAKISLDF+NKR+EHPEKCRSRT+N +WYGVLG  EL++RTY+NLEQ V LE DG  I LPSLQGI VLNIPSY GG+NFWG  KE D F +PSFDD++LEVVAV G+ QM +S+V   +QHHRIAQC TVKI+I  DE VPVQVDGEAW+QPPG ++IVHKNRA  L RDR FE TL+SW ++Q  ++ R        E +S  E   +    ++   L+ SI+  +  +  ++QEL  A +  S   ++V  +     G    F+  +   F +  +E    L  +++ +L+     ++ S+L++ D+++ +  D                       T     +  P + +S  L     A  S SG+  L+   K     +     +++       VH W   EV  WL+ +   EYKD F +HDI G EL+ LER DL DLGV KVGH KRIL   K+L+R
Sbjct:   33 PGSP-QKLIRKVSTSGQIRQ----KTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKD---IIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHT-SCKESLLTKCPLGLCKVSVIPPTALNSID--SDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKA----YEKTTESSEESEV----MAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPT-----------------------------IAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSH-------------------------SESF-----------GVPKGR--SQRKVSKSPCEKLISKGSLSLGSSASLP--PQPGSRDGLPALNTK--------------ILYPNV---RAGMSGSLPGGSVISRLLINADPF--------NSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVI-RLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLAD-----------------------TPWLCQSAEPGDEESVMLDL---AKRSRSGKFRLVTKFKKEKNNKNKEAHSSLG----APVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSR 1207          
The following BLAST results are available for this feature:
BLAST of TCONS_00050053-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
DGKD0.000e+041.85Diacylglycerol kinase delta OS=Homo sapiens GN=DGK... [more]
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