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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00050053-protein ID=TCONS_00050053-protein|Name=TCONS_00050053-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1403bp MSFYILLEKLLYFWLVIELTDIDFSIDDFQFRALHKYQLECNNNTQVKLD TESLENMSTRSGFYSVSSSSYEDEDERFLSEESKTTKSNVVEQEKSPPSK PGHSYTRKYSKYGKNKRNKSGEECIKEGYLMKQNGSFQRWKQTYFKIYPQ QIYYAKNPSSSLFHEINVTEISIAETSVNNVNNSFKVITGQISLSLSAET RREMEEWVSSFKLASQREGRNLNELSETLSGDHHWYSCTHSRPTFCNVCR DTLPGVTIKGLSCEVCRYKVHKKCAAKAPKSCKWTTLDCIPPEERLVGVG NDEYAMPHQWLEGNITPGQKCIVCGKLCGSKRRMQDFMCLWCDTVVHGGS CKLQFQKRCSLGLNCLSVIPATTIKRAEHLGPGVWEAIYHNRSPLIVFVN SKSGDNQGVKFMRRFKQLLNPAQVFDLSVAGPTLGVSMCKNFKQFRILVC GGDGSVGWVMTELDKQKLTNKCQIGVLPLGTGNDLARVFGWGSACYDVGV IPLVLQQLERARPSMLDRWAIMCKEFPSGRPEGDDISGYEDSIVMHITRM LASNQYEIVIQSAKFLCETIRNFVELVGVASGSEASNVASGSEASNVADL KLTSKCEVLQDKLTLLLRTLQIESEASSFLKSLDLTRRSSTMENLDIMAT LDGKKLKWHSDSELNTSMDSSRAKASGLGPGTDNAGFGQTKKTSKQKVFI PKEHLWSRANSLKKAMREIIDHTEKAVDEQNQQTSEAIAQCAAAVRSSNI STKGTHQPLSHILDDLPETIIDADEKDDTMEKGSLETESVKKDRVSATSP DGSPQHRNISAQDESDVMSDKAISKAKQDTKPISDKPNYPEYLSAPSSPF FNLKPDVFFAKNQKSSNTVVYPGTVIARAFQKPAVSDGFISKVLLANANA FCATALPGNEDEQDKLNNFKEKCVMNNYFGVGIDAKISLDFHNKREEHPE KCRSRTRNFIWYGVLGGMELINRTYRNLEQNVHLEVDGHKIHLPSLQGIV VLNIPSYMGGSNFWGTKKEVDGFVSPSFDDRMLEVVAVLGASQMGMSKVF GGMQHHRIAQCHTVKITITDEAVPVQVDGEAWMQPPGIVQIVHKNRAPML MRDREFEETLRSWHERQVHKVDRMAEPVSTPEMCLIKPLAESVTSLVRSI KAASMINSVVQQELYQAASNLSALAEKVRNQEVINRGEATEFIALSKGFI SDVNEKLWTLKPQLSQELETRIVSSLSQADQEMSKFLDNDDNKDSKDDIS LLQVDTHATAATTSTTNTVTPSNTKSSSLGNTGGASSSGSGRSWLMFGRK SHSCRERAPEATTIDFLEKKAVHEWDVNEVGLWLDTIGCSEYKDNFKQHD ITGPELIKLERHDLNDLGVKKVGHSKRILEKSKQLARYRKVPKPSKWTRK TVS Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term | Definition |
GO:0035556 | intracellular signal transduction |
GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway |
GO:0008152 | metabolic process |
Vocabulary: Molecular Function
Term | Definition |
GO:0004143 | diacylglycerol kinase activity |
GO:0005515 | protein binding |
GO:0016301 | kinase activity |
GO:0003951 | NAD+ kinase activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
biological_process |
GO:0035556 |
intracellular signal transduction |
biological_process |
GO:0008152 |
metabolic process |
biological_process |
GO:0007205 |
protein kinase C-activating G-protein coupled receptor signaling pathway |
molecular_function |
GO:0004143 |
diacylglycerol kinase activity |
molecular_function |
GO:0016301 |
kinase activity |
molecular_function |
GO:0003951 |
NAD+ kinase activity |
molecular_function |
GO:0005515 |
protein binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
None | No IPR available | COILS | Coil | Coil | coord: 712..733 |
None | No IPR available | GENE3D | 3.30.60.20 | | coord: 305..360 e-value: 7.8E-14 score: 51.0 |
None | No IPR available | GENE3D | 3.30.60.20 | | coord: 239..288 e-value: 3.5E-15 score: 55.1 |
None | No IPR available | GENE3D | 1.10.150.50 | | coord: 1321..1392 e-value: 2.9E-21 score: 74.9 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1262..1292 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 77..118 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 667..695 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 774..839 |
None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 300..362 |
None | No IPR available | SUPERFAMILY | 57889 | Cysteine-rich domain | coord: 226..285 |
IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | SMART | SM00109 | c1_12 | coord: 233..282 e-value: 4.0E-15 score: 66.2 coord: 308..359 e-value: 0.012 score: 23.8 |
IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PFAM | PF00130 | C1_1 | coord: 233..283 e-value: 2.3E-10 score: 40.1 |
IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS00479 | ZF_DAG_PE_1 | coord: 233..282 |
IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | PROSITE | PS50081 | ZF_DAG_PE_2 | coord: 232..282 score: 13.607 |
IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 308..360 e-value: 1.12916E-5 score: 43.6348 |
IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | CDD | cd00029 | C1 | coord: 233..282 e-value: 9.44738E-17 score: 75.9915 |
IPR000756 | Diacylglycerol kinase, accessory domain | SMART | SM00045 | dagk_c4b_2 | coord: 924..1081 e-value: 5.3E-88 score: 308.3 |
IPR000756 | Diacylglycerol kinase, accessory domain | PFAM | PF00609 | DAGK_acc | coord: 924..1080 e-value: 1.6E-49 score: 168.2 |
IPR001660 | Sterile alpha motif domain | SMART | SM00454 | SAM_4 | coord: 1322..1388 e-value: 2.8E-19 score: 80.1 |
IPR001660 | Sterile alpha motif domain | PFAM | PF00536 | SAM_1 | coord: 1324..1380 e-value: 8.8E-17 score: 61.2 |
IPR001660 | Sterile alpha motif domain | PROSITE | PS50105 | SAM_DOMAIN | coord: 1325..1388 score: 18.428 |
IPR001849 | Pleckstrin homology domain | SMART | SM00233 | PH_update | coord: 124..218 e-value: 1.4E-16 score: 71.1 |
IPR001849 | Pleckstrin homology domain | PFAM | PF00169 | PH | coord: 125..215 e-value: 1.7E-12 score: 47.7 |
IPR001849 | Pleckstrin homology domain | PROSITE | PS50003 | PH_DOMAIN | coord: 123..216 score: 14.595 |
IPR001206 | Diacylglycerol kinase, catalytic domain | SMART | SM00046 | dagk_c4a_7 | coord: 394..519 e-value: 1.5E-49 score: 180.6 |
IPR001206 | Diacylglycerol kinase, catalytic domain | PFAM | PF00781 | DAGK_cat | coord: 394..495 e-value: 6.3E-25 score: 87.1 |
IPR001206 | Diacylglycerol kinase, catalytic domain | PROSITE | PS50146 | DAGK | coord: 390..525 score: 36.674 |
IPR017438 | Inorganic polyphosphate/ATP-NAD kinase, domain 1 | GENE3D | 3.40.50.10330 | | coord: 388..528 e-value: 2.7E-29 score: 101.0 |
IPR011993 | PH domain-like | GENE3D | 2.30.29.30 | | coord: 122..238 e-value: 1.4E-19 score: 69.5 |
IPR011993 | PH domain-like | SUPERFAMILY | 50729 | PH domain-like | coord: 121..238 |
IPR013761 | Sterile alpha motif/pointed domain | SUPERFAMILY | 47769 | SAM/Pointed domain | coord: 1320..1387 |
IPR016064 | NAD kinase/diacylglycerol kinase-like domain | SUPERFAMILY | 111331 | NAD kinase/diacylglycerol kinase-like | coord: 392..521 coord: 921..1099 |
Blast
BLAST of TCONS_00050053-protein vs. Swiss-Prot (Human)
Match: DGKD (Diacylglycerol kinase delta OS=Homo sapiens GN=DGKD PE=1 SV=4) HSP 1 Score: 911.753 bits (2355), Expect = 0.000e+0 Identity = 552/1319 (41.85%), Postives = 730/1319 (55.34%), Query Frame = 0
Query: 98 PSKPGHSYTRKYSKYGKNKRNKSGEECIKEGYLMKQNGSFQRWKQTYFKIYPQQIYYAKNPSSSLFHEINVTEISIAETSVNNVNNSFKVITGQISLSLSAETRREMEEWVSSFKLASQREGRNLNELS-ETLSGDHHWYSCTHSRPTFCNVCRDTLPGVTIKGLSCEVCRYKVHKKCAAKAPKSCKWTTLDCIPPEERLVGVGNDEYAMPHQWLEGNITPGQKCIVCGKLCGSKRRMQDFMCLWCDTVVHGGSCKLQFQKRCSLGLNCLSVIPATTIKRAEHLGPGVWEAIY--HNRSPLIVFVNSKSGDNQGVKFMRRFKQLLNPAQVFDLSVAGPTLGVSMCKNFKQFRILVCGGDGSVGWVMTELDKQKLTNKCQIGVLPLGTGNDLARVFGWGSACYDVGVIPLVLQQLERARPSMLDRWAIMCKEFPSGR--------------PEGDDISGYEDSIVMHITRMLASNQYEIVIQSAKFLCETIRNFVELVGVASGSEASNVASGSEASNVADLKLTSKCEVLQDKLTLLLRTLQIESEASSFLKSLDLTRRSSTMENLDIMATLDGKKLKWHSDSELNTSMDSSRAKASGLGPGTDNAGFGQTKKTSKQKVFIPKEHLWSRANSLKKAMREIIDHTEKAVDEQNQQTSEAIAQCAAAVRSSNISTKGTHQPLSHILDDLPETIIDADEKDDTMEKGSLETESVKKDRVSATSPDGSPQHRNISAQDESDVMSDKAISKAKQDTKPISDKPNYPEYLSAPSSPFFNLKPDVFFAKNQKSSNTVVYPGTVIARAFQKPAVSDGFISKVLLANANAFCATALPGNEDEQDKLNNFKEKCVMNNYFGVGIDAKISLDFHNKREEHPEKCRSRTRNFIWYGVLGGMELINRTYRNLEQNVHLEVDGHKIHLPSLQGIVVLNIPSYMGGSNFWGTKKEVDGFVSPSFDDRMLEVVAVLGASQMGMSKVFGGMQHHRIAQCHTVKITIT-DEAVPVQVDGEAWMQPPGIVQIVHKNRAPMLMRDREFEETLRSWHERQVHKVDR------MAEPVSTPEMCLIKPLAESVTSLVRSIKAASMINSVVQQELYQAASNLSALAEKVRNQEVINRGEATEFI-ALSKGFISDVNEKLWTLKPQLSQELET----RIVSSLSQADQEMSKFLDNDDNKDSKDDISLLQVDTHATAATTSTTNTVTPSNTKSSSLGNTGGASSSGSGRSWLMFGRKSHSCRERAPEATTIDFLEKKAVHEWDVNEVGLWLDTIGCSEYKDNFKQHDITGPELIKLERHDLNDLGVKKVGHSKRILEKSKQLAR 1387
P P RK S G+ ++ + IKEG L KQN SFQR K+ YFK+ + +YYAK S +F E+++T+ S+AE+S NVNNSF VIT L L A+ R+EME+W+++ K RE + S + SG H+WY+C+H+RPT+CNVCR+ L GVT GLSCEVC++K HK+CA +A +CKWTTL I + + D AMPHQWLEGN+ KC VC K CGS R+QD+ CLWC +VH SCK +C LGL +SVIP T + + G W+A SPL+VFVNSKSGDNQGVKF+RRFKQLLNPAQVFDL GP LG+ + + F FRILVCGGDGSVGWV++E+D L +CQ+GVLPLGTGNDLARV GWGSAC D +P +L++LERA MLDRW++M E R E I YEDS+ H++++L S+Q+ +VI SAK LCET+++FV VG A SE S V + KC VL++KL LL+TL ES+ASS L + T + ++ SG G+ + ++ ++F P+E L RANSLKKA+R+II+HTEKAVDEQN QT E S PLSH +ES G P+ R S + S +K ISK + P P+ S P N K ++YP RA ++ G + LL NA+ F E + L + EKCVMNNYFG+G+DAKISLDF+NKR+EHPEKCRSRT+N +WYGVLG EL++RTY+NLEQ V LE DG I LPSLQGI VLNIPSY GG+NFWG KE D F +PSFDD++LEVVAV G+ QM +S+V +QHHRIAQC TVKI+I DE VPVQVDGEAW+QPPG ++IVHKNRA L RDR FE TL+SW ++Q ++ R E +S E + ++ L+ SI+ + + ++QEL A + S ++V + G F+ + F + +E L +++ +L+ ++ S+L++ D+++ + D T + P + +S L A S SG+ L+ K + +++ VH W EV WL+ + EYKD F +HDI G EL+ LER DL DLGV KVGH KRIL K+L+R
Sbjct: 33 PGSP-QKLIRKVSTSGQIRQ----KTIIKEGMLTKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITPCRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKD---IIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHT-SCKESLLTKCPLGLCKVSVIPPTALNSID--SDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFYEDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKA----YEKTTESSEESEV----MAKKCSVLKEKLDSLLKTLDDESQASSSLPNPPPT-----------------------------IAEEAEDGDGSGSICGSTGDRLVASACPARPQIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVCPPLSH-------------------------SESF-----------GVPKGR--SQRKVSKSPCEKLISKGSLSLGSSASLP--PQPGSRDGLPALNTK--------------ILYPNV---RAGMSGSLPGGSVISRLLINADPF--------NSEPETLEYYTEKCVMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVI-RLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCELPRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSMDRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMDRQLRRLAD-----------------------TPWLCQSAEPGDEESVMLDL---AKRSRSGKFRLVTKFKKEKNNKNKEAHSSLG----APVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILCGIKELSR 1207
The following BLAST results are available for this feature:
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