TCONS_00050513-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00050513-protein
Unique NameTCONS_00050513-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length762

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00050513-protein ID=TCONS_00050513-protein|Name=TCONS_00050513-protein|organism=Clytia hemisphaerica|type=polypeptide|length=762bp
MGVRRDFLLVFLLFGLVHSRGLQDDGIITKTAFISNIDSVNIATNHPKAT
EQTNVDENAETRSTIKNRKSSETTDETPVCDTQECRNVAKEIHLKMNETI
SPCDDFYEFACGRWINEKKIPSCENEITSFTVLTKTIENQIRKLIEQEPK
KEESKALQKARDFYQSCNNTKEIERLGAKPALDFIDSIGGWSLCNKDKWK
NEQSKKWNATEVLKKIQREFYPAPPFLSFEVTNDHLNSTKHLIKIDQSGL
SLQREIYCKHGKKKNILGDYKKYMTKVAQHLGYTCDTVEEEIGEILEFEK
KLAKLTTPAEAKQAGTFRRININILGKCISQFPWYEHIKAIFPKSANIKR
DDVVLATSPQYLYNVASLITSVDKRLLSKYIVWQMLRDKISFLSQPFRDA
RAAFNKKMTGVEDTEDRWRWCTSVTNDNMGVPIGTLYVNKYFSDETKNKT
QVMVDEVIDAFIRRIKNNHTWIDNTTKEHVIAKANAMVAKLGHATYIKNI
TALNIRFKDLNISSKEFFKNNLNVDRWIRLRLFNKLRKTVDKSKWPMFPQ
TINAMYQFYENEIVIPAGILQAPFYYNGSIPMPLSYGAIGSIIGHEITHG
FDNTGRKFDKNGDIKDEQWTQKSISNFCDKSHCLIKQYDKFKVRGKFPVH
GKLTLGENIADNGGVKLAYYAYRDWADQQDQETAALPRPLKYDNDQLFFI
GFAQQYCAKIREETEELATMSEIHSPSKFRVKGSLSNMKEFASTFKCPVG
SPMNPVKKCEVW
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031991XLOC_031991Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00050513TCONS_00050513Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR018497Peptidase_M13_C
IPR008753Peptidase_M13_N
IPR024079MetalloPept_cat_dom
IPR000718Peptidase_M13
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR018497Peptidase M13, C-terminal domainPRINTSPR00786NEPRILYSINcoord: 563..575
score: 74.54
coord: 585..601
score: 64.5
coord: 657..668
score: 75.0
coord: 545..557
score: 40.58
IPR018497Peptidase M13, C-terminal domainPFAMPF01431Peptidase_M13coord: 553..761
e-value: 3.9E-62
score: 209.4
IPR008753Peptidase M13, N-terminal domainPFAMPF05649Peptidase_M13_Ncoord: 102..492
e-value: 3.1E-97
score: 326.6
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 412..762
e-value: 3.3E-109
score: 364.7
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 78..263
e-value: 7.6E-20
score: 70.7
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 48..78
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 78..762
IPR000718Peptidase M13CDDcd08662M13coord: 100..760
e-value: 0.0
score: 648.209

Blast
BLAST of TCONS_00050513-protein vs. Swiss-Prot (Human)
Match: ECE1 (Endothelin-converting enzyme 1 OS=Homo sapiens GN=ECE1 PE=1 SV=2)

HSP 1 Score: 439.499 bits (1129), Expect = 2.041e-143
Identity = 241/694 (34.73%), Postives = 390/694 (56.20%), Query Frame = 0
Query:   74 TDETPVCDTQECRNVAKEIHLKMNETISPCDDFYEFACGRWINEKKIPSCENEITSFTVLTKTIENQIRKLIEQEPKKEESKALQKARDFYQSCNNTKEIERLGAKPALDFIDSIGGWSLCNKDKWKNEQSKKWNATEVLKKIQREFYPAPPFLSFEVTNDHLNSTKHLIKIDQSGLSL-QREIYCKHGKKKNILGDYKKYMTKVAQHLGYTCD-TVEEEIGEILEFEKKLAKLTTPAEAK--QAGTFRRININILGKCISQFPWYEHIKAIFPKSANIKRDDVVLATSPQYLYNVASLITSVDKRLLSKYIVWQMLRDKISFLSQPFRDARAAFNKKMTGVEDT-EDRWRWCTSVTNDNMGVPIGTLYVNKYFSDETKNKTQVMVDEVIDAFIRRIKNNHTWIDNTTKEHVIAKANAMVAKLGHATYIKNITALNIRFKDLNISSKEFFKNNLNVDRWIRLRLFNKLRKTVDKSKWPMFPQTINAMYQFYENEIVIPAGILQAPFYYNGSIPMPLSYGAIGSIIGHEITHGFDNTGRKFDKNGDIKDEQWTQKSISNFCDKSHCLIKQYDKFKVRGKFPVHGKLTLGENIADNGGVKLAYYAYRDWADQQDQETAALPRPLKYDNDQLFFIGFAQQYCAKIREETEELATMSEIHSPSKFRVKGSLSNMKEFASTFKCPVGSPMNPVKKCEVW 762
            T    VC ++ C +V   I   M+ T+ PC DF+ +ACG WI    +P   +   +F+ L +  +  I+ L+E       S+A +KA+ +Y++C N   IE L AKP ++ I+ +GGW++     W  +     N  + L+ +    Y   PF S  V+ D  NS  ++I++DQSGL L  R+ Y    + + +L  Y  YM ++ + LG   +  +  ++ +IL+FE  LA +T P E +  +   + ++    L        W   +  IF     I   + ++    +YL  +++LI + D+ LL+ Y++W ++R   SFL Q F+DA   F + M G + T   RW++C S T +N+G  +G ++V   F++++K+    ++ E+  AF   + +   W+D  T++    KA+A+   +G+  +I +   L+  F D       +F+N +    +      ++LRK  ++ +W M P  +NA Y   +NEIV PAGILQAPFY   S P  L++G IG ++GHE+TH FD+ GR++DK+G+++   W   S+  F  ++ C+++QY  + V G+ PV+G+ TLGENIADNGG+K AY AY++W  +   E  +LP  L   N+QLFF+GFAQ +C+    E+     +++ HSPS+FRV GSLSN KEF+  F+CP GSPMNP  KCEVW
Sbjct:   93 TRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENS-TASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWNITGP--WAKD-----NFQDTLQVVTAH-YRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIF-YPVEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESL-STLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSS-PKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLR-PWWKNSSVEAFKRQTECMVEQYSNYSVNGE-PVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAE-HSLPT-LGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770          
The following BLAST results are available for this feature:
BLAST of TCONS_00050513-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ECE12.041e-14334.73Endothelin-converting enzyme 1 OS=Homo sapiens GN=... [more]
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