TCONS_00053449-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00053449-protein
Unique Name	TCONS_00053449-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1011

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00053449-protein ID=TCONS_00053449-protein|Name=TCONS_00053449-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1011bp
STGKYMVTFPYPYMNGKLHLGHTFTISKCEFAVGYQRLKGKKCLFPFGFH
CTGMPIKACADKLKREMELFGCPPTFPSGDEKKDTTNMKSKVAAKTGGLT
YQWQIMQALDIPDEEIKSFADTAHWLKYFPPIATDDLKAMGLKVDWRRSF
ITTDANPYYDSFARWHFKKLKEAGKVKFGKRYTIFSAKDGQPCMDHDRLS
GEGVAPQEYTLIKMKVAAPLPEKLSSLEGKDIYLIAATLRPETMYGQTNC
WVHPDLPYIAFESSKENEILISTRRAAKNMAYQGLTKEENKVNIVLELVG
QDIMGVALNAPLTAHNVIYTLPMLTIKEDKGTGVVTSVPSDAPDDYAALR
DLKNKQPFRAKYNIADEMVLPYEPIPIIDVPELGNLPAIVACDKFKVNSQ
NDKIQLADAKELTYKKGFYEGVMLVEELKGLKVQDVKKQVQDKMVAEGQA
IIYMEPEKKVVSRSGDECIVSKCDQWYLDYGEESWKAEAKKLLGMMETYG
DETRHNFLATLDWLQEHACSRSFGLGSKIPWDEKYLIESLSDSTIYMAYY
TIAHFLQGSIYGRDTGLANASAAQMTDEVWDYIFLKEVDEIPTTDIDHEI
LRKMKAEFEFWYPLDLRVSGKDLIPNHLTYFLYNHVAVWNNKEEKWPKGV
RANGHLLLNSMKMSKSTGNFLTLKSAIGKFSADGMRLALADAGDTIEDAN
FVEKTADSGLLRLYTLIEWVKEMIESKESLRSGPMNDFNDQVFLSEINLT
INKTEEAFEKMQFREGLKSGLYEFQTVRDKYRELSIDGMHIDVVMKYIEV
QALLLSPICPHVSEHIWSLLGKPGSIMNASWPVSGDIDHGLLTCSQYLME
CARDFRLRLKNMIAAANKKKGKNPSVEVGKPTQGVVYVAKEYPPWQQVVL
KTLREMYTQNNNTFPENKEIMNALKTNADVKKHMKKLMPFVAHLKTRVAT
EGVSAMDLSVSFDETTVLMDNLTYLLKSIELENIEIKPSTEAEAKVQEEC
APGKPYSIFKS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_033743	XLOC_033743	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00053449	TCONS_00053449	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR004493	Leu-tRNA-synth_Ia_arc/euk
IPR002300	aa-tRNA-synth_Ia
IPR014729	Rossmann-like_a/b/a_fold
IPR013155	M/V/L/I-tRNA-synth_anticd-bd
IPR009080	tRNAsynth_Ia_anticodon-bd
IPR001412	aa-tRNA-synth_I_CS
IPR009008	Val/Leu/Ile-tRNA-synth_edit

Vocabulary: **Molecular Function**
Term	Definition
GO:0005524	ATP binding
GO:0004823	leucine-tRNA ligase activity
GO:0000166	nucleotide binding
GO:0004812	aminoacyl-tRNA ligase activity
GO:0002161	aminoacyl-tRNA editing activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006429	leucyl-tRNA aminoacylation
GO:0006418	tRNA aminoacylation for protein translation

Vocabulary: **Cellular Component**
Term	Definition
GO:0005737	cytoplasm

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006429	leucyl-tRNA aminoacylation
biological_process	GO:0006418	tRNA aminoacylation for protein translation
cellular_component	GO:0005737	cytoplasm
molecular_function	GO:0002161	aminoacyl-tRNA editing activity
molecular_function	GO:0004812	aminoacyl-tRNA ligase activity
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004823	leucine-tRNA ligase activity
molecular_function	GO:0000166	nucleotide binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR004493	Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic	TIGRFAM	TIGR00395	TIGR00395	coord: 3..1006 e-value: 7.9E-285 score: 945.4
IPR002300	Aminoacyl-tRNA synthetase, class Ia	PFAM	PF00133	tRNA-synt_1	coord: 3..62 e-value: 2.2E-8 score: 32.7 coord: 123..701 e-value: 7.1E-27 score: 93.8
IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	GENE3D	3.40.50.620		coord: 2..696 e-value: 3.7E-93 score: 311.8
IPR013155	Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding	PFAM	PF08264	Anticodon_1	coord: 740..869 e-value: 5.0E-19 score: 68.7
IPR009080	Aminoacyl-tRNA synthetase, class Ia, anticodon-binding	GENE3D	1.10.730.10		coord: 697..836 e-value: 5.5E-22 score: 78.0
IPR009080	Aminoacyl-tRNA synthetase, class Ia, anticodon-binding	SUPERFAMILY	47323	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	coord: 711..834
IPR001412	Aminoacyl-tRNA synthetase, class I, conserved site	PROSITE	PS00178	AA_TRNA_LIGASE_I	coord: 12..23
None	No IPR available	CDD	cd07959	Anticodon_Ia_Leu_AEc	coord: 701..820 e-value: 4.29584E-43 score: 152.745
None	No IPR available	CDD	cd00812	LeuRS_core	coord: 449..703 e-value: 6.39843E-68 score: 229.056
None	No IPR available	SUPERFAMILY	52374	Nucleotidylyl transferase	coord: 118..199 coord: 3..62 coord: 458..706
IPR009008	Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain	SUPERFAMILY	50677	ValRS/IleRS/LeuRS editing domain	coord: 419..457 coord: 226..379

Blast

[Close]

BLAST of TCONS_00053449-protein vs. Swiss-Prot (Human)
Match: SYLC (Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens GN=LARS PE=1 SV=2)

HSP 1 Score: 1367.44 bits (3538), Expect = 0.000e+0
Identity = 641/1026 (62.48%), Postives = 799/1026 (77.88%), Query Frame = 0

Query:    1 STGKYMVTFPYPYMNGKLHLGHTFTISKCEFAVGYQRLKGKKCLFPFGFHCTGMPIKACADKLKREMELFGCPPTFPSGDEKKDTTNMKSK--------------VAAKTGGLTYQWQIMQALDIPDEEIKSFADTAHWLKYFPPIATDDLKAMGLKVDWRRSFITTDANPYYDSFARWHFKKLKEAGKVKFGKRYTIFSAKDGQPCMDHDRLSGEGVAPQEYTLIKMKVAAPLPEKLSSLEGKDIYLIAATLRPETMYGQTNCWVHPDLPYIAFESSKENEILISTRRAAKNMAYQGLTKEENKVNIVLELVGQDIMGVALNAPLTAHNVIYTLPMLTIKEDKGTGVVTSVPSDAPDDYAALRDLKNKQPFRAKYNIADEMVLPYEPIPIIDVPELGNLPAIVACDKFKVNSQNDKIQLADAKELTYKKGFYEGVMLVEELKGLKVQDVKKQVQDKMVAEGQAIIYMEPEKKVVSRSGDECIVSKCDQWYLDYGEESWKAEAKKLLGMMETYGDETRHNFLATLDWLQEHACSRSFGLGSKIPWDEKYLIESLSDSTIYMAYYTIAHFLQ-GSIYGRDTGLANASAAQMTDEVWDYIFLKEVDEIPTTDIDHEILRKMKAEFEFWYPLDLRVSGKDLIPNHLTYFLYNHVAVWNNKEEKWPKGVRANGHLLLNSMKMSKSTGNFLTLKSAIGKFSADGMRLALADAGDTIEDANFVEKTADSGLLRLYTLIEWVKEMIESKESLRSGPMNDFNDQVFLSEINLTINKTEEAFEKMQFREGLKSGLYEFQTVRDKYRELSIDGMHIDVVMKYIEVQALLLSPICPHVSEHIWSLLGKPGSIMNASWPVSGDIDHGLLTCSQYLMECARDFRLRLKN-MIAAANKKKGKNPSVEVGKPTQGVVYVAKEYPPWQQVVLKTLREMYTQNNNTFPENKEIMNALKTNADVKKHMKKLMPFVAHLKTRVATEGVSAMDLSVSFDETTVLMDNLTYLLKSIELENIEIKPSTEAEAKVQEECAPGKPYSIFK 1010
            S GKY VTFPYPYMNG+LHLGHTF++SKCEFAVGYQRLKGK CLFPFG HCTGMPIKACADKLKRE+EL+GCPP FP  +E+++ T++K++               AAK G   YQW IM++L + DEEI  F++  HWL YFPP+A  DLK MGLKVDWRRSFITTD NPYYDSF RW F  L+E  K+KFGKRYTI+S KDGQPCMDHDR +GEGV PQEYTL+K+KV  P P KLS L+GK+I+L+AATLRPETM+GQTNCWV PD+ YI FE+    +I I T++AA+NM+YQG TK+   V +V EL+G++I+G +L+APLT++ VIY LPMLTIKEDKGTGVVTSVPSD+PDD AALRDLK KQ  RAKY I D+MVLP+EP+P+I++P  GNL A+  CD+ K+ SQND+ +LA+AKE  Y KGFYEG+MLV+  KG KVQDVKK +Q KM+  G A+IYMEPEK+V+SRS DEC+V+ CDQWYLDYGEE+WK +  + L  +ET+ +ETR NF ATL WLQEHACSR++GLG+ +PWDE++LIESLSDSTIYMA+YT+AH LQ G+++G+          QMT EVWDY+F KE    P T I  E L ++K EFEFWYP+DLRVSGKDL+PNHL+Y+LYNHVA+W  + +KWP  VRANGHLLLNS KMSKSTGNFLTL  AI KFSADGMRLALADAGDT+EDANFVE  AD+G+LRLYT +EWVKEM+ + +SLRSGP + FND+VF SE+N  I KT++ +EKM F+E LK+G +EFQ  +DKYREL+++GMH ++V ++IEVQ LLL+P CPH+ EHIW+LLGKP SIMNASWPV+G ++  L+  SQYLME   D RLRLKN M+ A  KK  K P   + KP+   +YVAK YPPWQ   L  LR+ +  NN   P+NK I + L +  ++KK+MKK+MPFVA +K  +   G   +DL + FDE  VLM+N+ YL  S+ELE+IE+K ++EAE K++E+C PGKP ++F+
Sbjct:   42 SKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVN-GDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAESPLGIRPQQMTKEVWDYVFFKEA-PFPKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQP---LQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVLMENIVYLTNSLELEHIEVKFASEAEDKIREDCCPGKPLNVFR 1062

The following BLAST results are available for this feature:

BLAST of TCONS_00053449-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00053449-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
SYLC	0.000e+0	62.48	Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens ...	[more]

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TCONS_00053449-protein (polypeptide) - C. hemisphaerica