TCONS_00056553-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00056553-protein
Unique NameTCONS_00056553-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length453

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00056553-protein ID=TCONS_00056553-protein|Name=TCONS_00056553-protein|organism=Clytia hemisphaerica|type=polypeptide|length=453bp
MSLVFILVLIAAIQNHAEIIEPQNKKTFERKINTTPSYGVPYAYKINTTS
SDDAPNSNKSNVILNGGPCQRKPPSAKDSVFITIFSLIFIVGVTGNIVAI
VIIVLSKRLNSMPTNLFVVALAVCDIGAITFVIPIRIDNLFHSHNFCFNA
HVCRMFTFTELLFHSASISHLFVIAIERFVAVNYPFVYQRVMNRTFTIML
SLYTWCYALVWACLSQFNWEDPSNRSTWFYEDSRTKLCLVRNRIYFNVSL
IMVYILPLAVMGGLYLSILRVALKQARIIESLSVHRDQSVKKQRREVRAT
KTLAIIYGAFTVCWLPVSLISLTVQWVPHKYREFRTDFPKLSEVIFALFI
EVLPTLNSSLNPFLYLFFNKKVRQEMQSYYERFRNISPTFQMDSDSSIGQ
VAIRSKYLGDNSKLSTNFESNSNHNQSTTKPTEEQNRQNIDELNPGRTSS
VRL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_035633XLOC_035633Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00056553TCONS_00056553Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: Biological Process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0004930G-protein coupled receptor activity
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007186 G-protein coupled receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004930 G-protein coupled receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 347..373
score: 30.48
coord: 114..135
score: 28.46
coord: 160..182
score: 28.88
coord: 299..323
score: 31.5
coord: 246..269
score: 24.66
coord: 80..104
score: 23.53
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 95..365
e-value: 1.3E-39
score: 136.0
IPR000276G protein-coupled receptor, rhodopsin-likePROSITEPS00237G_PROTEIN_RECEP_F1_1coord: 166..182
NoneNo IPR availableGENE3D1.20.1070.10coord: 45..445
e-value: 2.2E-66
score: 223.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 414..453
NoneNo IPR availableSUPERFAMILY81321Family A G protein-coupled receptor-likecoord: 74..388
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 95..365
score: 36.962

Blast
BLAST of TCONS_00056553-protein vs. Swiss-Prot (Human)
Match: HRH2 (Histamine H2 receptor OS=Homo sapiens GN=HRH2 PE=2 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 2.040e-27
Identity = 92/330 (27.88%), Postives = 164/330 (49.70%), Query Frame = 0
Query:   54 APNSNKSNVILNGGPCQRKPPSAKDSVFITI-FSLIFIVGVTGNIVAIVIIVLSKRLNSMPTNLFVVALAVCDIGAITFVIPIRIDNLFH-SHNFCFNAHVCRMFTFTELLFHSASISHLFVIAIERFVAVNYPFVYQRVMNRTFTIMLSLYTWCYALVWACLS-QFNWEDPSNRSTWFYEDSRTKLCLVRNRIYFNVSLIMVYILPLAVMGGLYLSILRVALKQARIIESLSVHRDQSVKKQRREVRATKTLAIIYGAFTVCWLPVSLISLTVQWVPHKYREFRTDFPKLSEVIFALFIEVLPTLNSSLNPFLYLFFNKKVRQEMQSYY 380
            APN   S+  L+   C+         + IT+  +++ ++ V GN+V  + + L++RL ++ TN F+V+LA+ D+     V+P     ++  S  + F    C ++T  +++  +ASI +LF+I+++R+ AV  P  Y  ++      +  +  W  ++  + LS    W   +  S   +  S+ K+ +  N +Y  V  ++ + LPL +M   Y  I +VA  QA+ I  +S  +  ++    RE +AT TLA + GAF +CW P         +    YR  R D   ++EV+ A+ +  L   NS+LNP LY   N+  R   Q  +
Sbjct:    2 APNGTASSFCLDSTACK---------ITITVVLAVLILITVAGNVVVCLAVGLNRRLRNL-TNCFIVSLAITDLLLGLLVLPF--SAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQV--NEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATI----REHKATVTLAAVMGAFIICWFP--------YFTAFVYRGLRGD-DAINEVLEAIVLW-LGYANSALNPILYAALNRDFRTGYQQLF 303          
The following BLAST results are available for this feature:
BLAST of TCONS_00056553-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
HRH22.040e-2727.88Histamine H2 receptor OS=Homo sapiens GN=HRH2 PE=2... [more]
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