TCONS_00057961-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00057961-protein
Unique NameTCONS_00057961-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length763

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00057961-protein ID=TCONS_00057961-protein|Name=TCONS_00057961-protein|organism=Clytia hemisphaerica|type=polypeptide|length=763bp
VAGDSLELEDIIGQGQFGDVYKGMYTSPKTKTTTSVAIKTYREDREKENE
DATRSEKFLEEAYLMKQFDHPHIIKLIGIVSSNPIRIIMELAPHGELRSY
LQHYRLQTDIEKLVTYIFQLCTALSYLESRNFVHRDVAARNILVSDINTI
KLGDFGLSRSIEDHHSYYKASKGKLPIKWMAPESINFRRFSSASDVWMFG
VCCWEILMYGVKPFQGVPNEKVIGKIENGERLPLPQTCPINLYHIMTDAW
NYEPSKRPTFQELKTKLGSIVHEERFSGQQKKKKHDERRAKLPGQDESLA
PPKPSRPTPFNTDAKSVTLPRSLNQSPQAFDTTKTICTSSLPRPFNKNLL
DPHKQRMSWASSRFNNIQEKQKRDAEEKVKQIRKTLQEQEHLQERLRQQK
EESDADNEWLKSEDEKAYVETASQGDPSSPTDPSTTEPSTTDEVDSKTRL
SKRHSYNGEKTEYDKDRLSEVWDRKMEQTKNAKSLNLRQSTNHLRRNTPF
RASMPLWAPMASTDEQRPKTQEGRPLPPVPSSPTEVERPTQPAPPLKTKN
DNPPPPKPERSLSSEAKASNSDDEYARPQKHKNDDMDPAAMRRSKTISAV
DRPKSRDSPGMLRRNTETARSSRAKEVLPANDIVYQHTTSVVKSVIEFNT
GVQHAQPEEFVDLVKVVGLNLRDLLAEVDNGVQNIPESAQKEIEMAHKVL
SSDMAELVAKMKLAQKYAETTLGQENKRLMLAAAHALAIDAKNLYDTYSK
VRENSLNNENNLS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_036536XLOC_036536Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00057961TCONS_00057961Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR020635Tyr_kinase_cat_dom
IPR005189Focal_adhesion_kin_target_dom
IPR017441Protein_kinase_ATP_BS
IPR008266Tyr_kinase_AS
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004871signal transducer activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007172signal complex assembly
Vocabulary: Cellular Component
TermDefinition
GO:0005925focal adhesion
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007172 signal complex assembly
cellular_component GO:0005925 focal adhesion
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
molecular_function GO:0004871 signal transducer activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 365..406
NoneNo IPR availableCOILSCoilCoilcoord: 42..62
NoneNo IPR availableGENE3D3.30.200.20coord: 1..91
e-value: 5.5E-21
score: 74.0
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 2..108
e-value: 0.033
score: 10.2
coord: 102..417
e-value: 6.4E-50
score: 168.1
NoneNo IPR availableGENE3D1.20.120.330coord: 631..754
e-value: 7.0E-46
score: 154.8
NoneNo IPR availableGENE3D1.10.510.10coord: 92..429
e-value: 1.8E-51
score: 174.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 390..624
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 271..350
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 89..102
score: 38.64
coord: 175..185
score: 65.7
coord: 126..144
score: 65.58
coord: 238..260
score: 44.3
coord: 194..216
score: 50.34
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 6..267
e-value: 8.7E-90
score: 300.4
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 6..267
e-value: 5.2E-120
score: 414.7
IPR005189Focal adhesion kinase, targeting (FAT) domainPFAMPF03623Focal_ATcoord: 630..753
e-value: 4.1E-44
score: 149.6
IPR005189Focal adhesion kinase, targeting (FAT) domainPRODOMPD006413coord: 630..728
e-value: 2.0E-22
score: 266.0
IPR005189Focal adhesion kinase, targeting (FAT) domainSUPERFAMILY68993FAT domain of focal adhesion kinasecoord: 630..753
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 12..39
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 132..144
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 6..275
score: 39.806
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 4..270

Blast
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BLAST of TCONS_00057961-protein vs. Swiss-Prot (Human)
Match: FAK1 (Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE=1 SV=2)

HSP 1 Score: 385.185 bits (988), Expect = 1.084e-119
Identity = 213/430 (49.53%), Postives = 271/430 (63.02%), Query Frame = 0 
Query:    6 LELEDIIGQGQFGDVYKGMYTSPKTKTTTSVAIKTYREDREKENEDATRSEKFLEEAYLMKQFDHPHIIKLIGIVSSNPIRIIMELAPHGELRSYLQHYRLQTDIEKLVTYIFQLCTALSYLESRNFVHRDVAARNILVSDINTIKLGDFGLSRSIEDHHSYYKASKGKLPIKWMAPESINFRRFSSASDVWMFGVCCWEILMYGVKPFQGVPNEKVIGKIENGERLPLPQTCPINLYHIMTDAWNYEPSKRPTFQELKTKLGSIVHEERFSGQQKKKKHDERRAKLP----GQDESLAPPKPSRPTPFNTDAKSVTLPRS---LNQSPQAFDTTKTICTSSLP------------RPFNKNLLDPHKQRMSWASSRFNNIQEKQKRDAEEKVKQIRKTLQE--QEHLQERLRQQKEESDADNEWLKSED 414
            +EL   IG+GQFGDV++G+Y SP+     +VAIKT +        D+ R EKFL+EA  M+QFDHPHI+KLIG+++ NP+ IIMEL   GELRS+LQ  +   D+  L+ Y +QL TAL+YLES+ FVHRD+AARN+LVS  + +KLGDFGLSR +ED  +YYKASKGKLPIKWMAPESINFRRF+SASDVWMFGVC WEILM+GVKPFQGV N  VIG+IENGERLP+P  CP  LY +MT  W Y+PS+RP F ELK +L +I+ EE+   +++ +    R+A +     G DE  APPKPSRP            PRS      SPQ    T     S  P             P   +LLD   Q  SW + R   I   Q    +  V  +R   Q      ++ERL +Q++E + D  WL+ E+
Sbjct:  422 IELGRCIGEGQFGDVHQGIYMSPENPAL-AVAIKTCKNC----TSDSVR-EKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS-TYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDE--APPKPSRP--------GYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLD---QTDSW-NHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEE 830

HSP 2 Score: 135.961 bits (341), Expect = 1.094e-32
Identity = 69/128 (53.91%), Postives = 91/128 (71.09%), Query Frame = 0 
Query:  630 ANDIVYQHTTSVVKSVIEFNTGVQHAQPEEFVDLVKVVGLNLRDLLAEVDNGVQNIPESAQKEIEMAHKVLSSDMAELVAKMKLAQKYAETTLGQENKRLMLAAAHALAIDAKNLYDTYSKVRENSLN 757
            +ND VY++ T +VK+VIE ++ +Q A PEE+V +VK VGL LR LLA VD  +  +P S  +EIEMA K+L+SD+ EL+ KMKLAQ+Y  T+L QE K+ ML AAHALA+DAKNL D   + R   L 
Sbjct:  920 SNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLG 1047
The following BLAST results are available for this feature:
BLAST of TCONS_00057961-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FAK11.084e-11949.53Focal adhesion kinase 1 OS=Homo sapiens GN=PTK2 PE... [more]
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