TCONS_00059178-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00059178-protein
Unique NameTCONS_00059178-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length634

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00059178-protein ID=TCONS_00059178-protein|Name=TCONS_00059178-protein|organism=Clytia hemisphaerica|type=polypeptide|length=634bp
MWDIEYLPLILENPVPSDISISRSQKPKYIGKLAEELKIQPEEVDYYGKT
KAKVGLSILERLKDQKDGKYVVVAGITPTPLGEGKSTTTIGLAQSLSSAL
KKQCFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITA
ANNLLAAAIDARIFHESTQSDKALFNRLCPKKKGIREFTPIMLRRLKKLG
IEKSNPDDLTDEEKGKFARLDFDTSTITWQRVLDTNDRYLRKITVGQSPT
EKGRTRECQFDITVASEIMAVLALTTDLRDMRDRLGNMVVASNKEGMPIT
ADDLGVGGALTVLMKDAIKPNLMQTLEGSPVFVHAGPFANIAHGNSSILA
DKIALKLVGQDGFVVTECGFGADIGMEKFFNIKCRYSGLLPSCVVLVATV
RALKMHGGGPKVVAGSPLPEAYTTENIELVEKGFCNLRKQIENALCFGVP
VVVAVNKFHTDTDGEINKMISLSKEAGAFDAVLCTHYAEGGQGAVNLSQA
VIKASEEKTNFRFLYDLKLPLEEKIEIIAKRIYGADGVSFSDQAKESLAR
YTKQGFSELPICMAKTHLSLSDNPELKGAPTGFTLPIRDVRASVGAGFVF
PLVGTMSTMPGLPTRPCFYDIDLDPDTEEVQGLM
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_037271XLOC_037271Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00059178TCONS_00059178Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000559Formate_THF_ligase
IPR020628Formate_THF_ligase_CS
IPR027417P-loop_NTPase
Vocabulary: Molecular Function
TermDefinition
GO:0004329formate-tetrahydrofolate ligase activity
GO:0005524ATP binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005524 ATP binding
molecular_function GO:0004329 formate-tetrahydrofolate ligase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000559Formate-tetrahydrofolate ligase, FTHFSPFAMPF01268FTHFScoord: 17..634
e-value: 5.1E-260
score: 863.3
IPR000559Formate-tetrahydrofolate ligase, FTHFSHAMAPMF_01543FTHFScoord: 15..634
score: 41.599
IPR000559Formate-tetrahydrofolate ligase, FTHFSCDDcd00477FTHFScoord: 32..617
e-value: 0.0
score: 915.39
NoneNo IPR availableGENE3D3.40.50.300coord: 305..519
e-value: 4.3E-81
score: 271.7
coord: 27..304
e-value: 6.4E-92
score: 307.2
NoneNo IPR availableGENE3D3.10.410.10coord: 521..609
e-value: 6.1E-39
score: 131.5
IPR020628Formate-tetrahydrofolate ligase, FTHFS, conserved sitePROSITEPS00722FTHFS_2coord: 397..408
IPR020628Formate-tetrahydrofolate ligase, FTHFS, conserved sitePROSITEPS00721FTHFS_1coord: 118..128
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 18..165
coord: 217..627

Blast
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BLAST of TCONS_00059178-protein vs. Swiss-Prot (Human)
Match: C1TC (C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3)

HSP 1 Score: 957.977 bits (2475), Expect = 0.000e+0
Identity = 477/633 (75.36%), Postives = 541/633 (85.47%), Query Frame = 0 
Query:    2 WDIEYLPLILENPVPSDISISRSQKPKYIGKLAEELKIQPEEVDYYGKTKAKVGLSILERLKDQKDGKYVVVAGITPTPLGEGKSTTTIGLAQSLSSALKKQCFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLLAAAIDARIFHESTQSDKALFNRLCPKKKGIREFTPIMLRRLKKLGIEKSNPDDLTDEEKGKFARLDFDTSTITWQRVLDTNDRYLRKITVGQSPTEKGRTRECQFDITVASEIMAVLALTTDLRDMRDRLGNMVVASNKEGMPITADDLGVGGALTVLMKDAIKPNLMQTLEGSPVFVHAGPFANIAHGNSSILADKIALKLVGQDGFVVTECGFGADIGMEKFFNIKCRYSGLLPSCVVLVATVRALKMHGGGPKVVAGSPLPEAYTTENIELVEKGFCNLRKQIENALCFGVPVVVAVNKFHTDTDGEINKMISLSKEAGAFDAVLCTHYAEGGQGAVNLSQAVIKASEEKTNFRFLYDLKLPLEEKIEIIAKRIYGADGVSFSDQAKESLARYTKQGFSELPICMAKTHLSLSDNPELKGAPTGFTLPIRDVRASVGAGFVFPLVGTMSTMPGLPTRPCFYDIDLDPDTEEVQGLM 634
            W I+Y  L L+ PVPSDI ISRS KPK IGKLA E+ +  EEV+ YG+TKAKV LS LERLK + DGKYVVV GITPTPLGEGKSTTTIGL Q+L + L +  FACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNL+AAAIDARIFHE TQ+DKALFNRL P   G+R F+ I +RRLK+LGIEK++P  LTDEE  +FARLD D  TITWQRVLDTNDR+LRKIT+GQ+PTEKG TR  QFDI+VASEIMAVLALTT L DMR+RLG MVVAS+K+G P++A+DLGV GALTVLMKDAIKPNLMQTLEG+PVFVHAGPFANIAHGNSSI+AD+IALKLVG +GFVVTE GFGADIGMEKFFNIKCRYSGL P  VVLVATVRALKMHGGGP V AG PLP+AY  EN+ELVEKGF NL+KQIENA  FG+PVVVAVN F TDT+ E++ +  LS+E GAFDAV CTH+AEGG+GA+ L+QAV +A++  ++F+ LYDLKLP+E+KI IIA++IYGAD +    +A+     YTKQGF  LPICMAKTHLSLS NPE KG PTGF LPIRD+RASVGAGF++PLVGTMSTMPGLPTRPCFYDIDLDP+TE+V GL 
Sbjct:  303 WMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPVSAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAFDAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF 935
The following BLAST results are available for this feature:
BLAST of TCONS_00059178-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
C1TC0.000e+075.36C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo... [more]
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